Objective To investigate the resistance and infection case for the Multidrug-Resistant Acinetobacter baumanii (MDRAb) strains.Methods Retrospective study.Thirty-eight MDRAb strains were collected in Beijing Friendship Hospital from February to August 2008.VITEK2-compact system was used to detect the MDRAb.PCR was carried out to detect their resistance related genes and look up the medical records those who were infected by MDRAb.Results The resistance rate of the MDRAb is the highest in ICU.PCR confirmed that OXA-23 and OXA-51 were 100％ related with the MDRAb.Combination drug therapy such as sulbactam combined with β-lactam antibiotics was more effective than β-lactam antibiotics only to treat the infection with MDRAb.Cases analysis showed that a number of patients infected by MDRAb were the aged with basic diseases,low immunity,received a variety of antibiotic therapy even traumatic operation,and they had a poor prognosis finally.Conclusions The resistance rate of the MDRAb is the highest in ICU,OXA-23 is closely related to multidrug-resistance.Combination drug therapy is necessary and sulbactam can play a great role in curing the inpatients infected with MDRAb.

Objective of electroacupuncture(EA) of Alzheimer′s disease(AD) rat learning and memory ability and plasma SOD , MDA content in brain P53 ,P21 expression .Methods The normal 36 SD rats ,were randomly divided into sham operation group , model group and EA group .EA group acupuncture “Baihui” ,“Taixi” ,“Zusanli” treatment ,through the Morris water maze test in rats behavioral changes ,spectrophotometric observation of SOD and MDA in rat plasma levels ;observation of rat brain P53 ,P21 ex-pression by immunofluorescence .Results Compared With the model group ,group EA escape latency ,longer in the third quadrant of the activities of the time ,the number of crossing platform position increased ,decreased the elevated plasma SOD level ,MDA lev-el ,reduce the expression of brain P53 ,P21 ,and the difference was statistically significant (P<0 .01) .Conclusion electro-acupunc-ture treatment can improve the Aβ1-42-induced AD rat spatial learning and memory ability ,may be lowered P53 ,P21 protein ex-pression increase SOD activity and MDA .

The traditional Najiafa (day-prescription of acupoints) can be classified into two schools of YAN Ming-guang and XU Feng. The author studied the YAN Ming-guang and XU Feng Najia fa from the aspects of the academic source, selection of points, existing researches and current application. When compared between the two schools, it is held that Najia fa of YAN Ming-guang school more accords with the law of point selection according to Ziwu Liuzhu Zhenfa (acupuncture based on the midnight-noon and ebb-flow doctrine) in following the original doctrine, selection of points on the base of day-prescription, and time-meridian relation of Sanjiao (triple energizer) and Pericardium meridians. Therefore, it is concluded that the YAN's Najia fa should not be neglected and forgotten. Its inheritage and further study should be carried out so as to enrich the ways of study as well as the prevention and treating methods in clinic.
Acupuncture Points ; Acupuncture Therapy ; history ; China ; History, Ancient ; Humans ; Medicine in Literature ; Meridians

Atomoxetine as a nonstimulant medicine was approved by the Chinese Food an Drug Administration and provide a new selection of treatment drugs for attention deficit hyperactivity disorder (ADHD). Tomoxetine is a noradrenaline transmitter reuptake inhibitor which can selectively inhibit synapsis noradrenaline transport protein, strengthen noradrenaline's resupination effect, and increase noradrenaline's activity released by synaptic cleft to improve the symptoms of the ADHD patients. Compared with methylphenidate, atomoxetine does not affect the concentration of the neurotransmitter dopamine and does not induce or increase the Tourettes' syndrome, therefore atomoxetine is more suitable to treat ADHD together with Tourettes syndrome. In this article the treatment of atomoxetine for ADHD, including the indications, dosage as well as adverse reactions and efficacy assessment are reviewed.

Physical constitution theory is an important part of traditional Chinese medicine theory. Physical constitution is associated with the incidence, development and prognosis of diseases. Gene polymorphism is a result of the interaction between internal and external environments during the human evolution, and it is the reason for differences in biological characteristics and disease susceptibility of individuals. Current status of the research on physical constitution theory, lung cancer syndromes and gene polymorphism are summarized in this paper. Exploring lung cancer syndromes from the point of view of gene polymorphism may reveal the scientific connotation of lung cancer syndromes, and provide new evidence and method for diagnosis of lung cancer.

As a kind of new technology, ethical issues are inevitable in medical and non-medical gene en-hancement application. It is unrealistic to unilaterally support or object to the research and application of medical and non -medical gene enhancement. Based on standardizing the ethical principle of gene enhancement tech-niques, we should build management measures of the research, development and application that adapted to ethi-cal, social and legal standards, so that we can draw on the advantages and avoid the disadvantages, and use gene enhancement reasonably and bring benefits to mankind and society.

Objective To explore the MRI characteristics of saddle transverse carpal ligament (TCL)of patients with idiopathic carpal tunnel syndrome (CTS). Methods The clinical diagnosis of 21 cases of idiopathic CTS patients (22 wrists) were retrospectively analyzed and as the idiopathic CTS group. Thirty two patients without CTS symptoms or TCL and volar soft tissue lesions (33 wrist joints) were selected as the control group. Patients in two groups were both conducted with sagittal and axial MRI scan of wrist joint to observe the form of the TCL, determine whether the TCL saddle and calculate the TCL palmar concave curvature and the median nerve compression rate. The differences of the morphology of the TCL of patients in two groups were compared by Chi?square criterion, and the difference of the TCL palmar concave curvature were compared by non parametric test. The relativity of TCL palmar correlation concave curvature and compression ratio of the median nerve of patients with idiopathic CTS was evaluated by the Pearson correlation analysis.Results The sagittal plane of patients with idiopathic CTS was upper, saddle shaped TCL was dented to the palmar and the concave point most frequently located in the hamate hook. Thirty one patients were with saddle shaped TCL (20 patients with idiopathic CTS and 11 patients in the control group) and 24 patients were with non saddle shaped TCL (2 patients with idiopathic CTS and 22 patients in the control group) as the standard of saddle shaped TCL concave 0.25 mm and the difference of the morphology of the TCL of patients in two groups had statistical significance (χ2= 17.791, P<0.01). The median of TCL palmar concave curvature of patients with idiopathic CTS and patients in the control group was 8.49%and 0.00%, respectively, the difference of which was statistically significant (Z=-4.79, P<0.01). The level of the median nerve, the TCL palmar concave curvature [(7.88+4.28)%] and the median nerve compression rate [(39.36 + 19.43)% ] of patients with idiopathic CTS were positively correlated (r=0.714, P<0.01). Conclusions Saddle shaped TCL is the characteristic manifestation of patients with idiopathic CTS. The TCL sagittal concave palm and median nerve compression percentage rate are both helpful to the accurate diagnosis.

Relevant projects carried out within the Yangtze River economic belt on the impact of schistosomiasis epidemic and transmission are important issues for ecological priority in the process of implementing the strategy. The key problems of schistosomiasis epidemic risk,epidemic happening repeatedly,difficulty of rehabilitating Oncomelania hupensis snail control and schistosomiasis prevention forest,lag of evaluation system and platform construction,lack of basic research,et al. were ana-lyzed in the Yangtze River economic belt taking ecological priority as the basis in this paper. Then corresponding countermea-sures to these challenges were put forward so as to provide the reference for the national forestry schistosomiasis control pro-grams,which include:execution of the comprehensive prevention and control strategy,scheming of the new round of forestry schistosomiasis control programs,strengthening schistosomiasis prevention and control,promoting productivity in existing forest-ry to consolidate and improve the achievements of previous forestry schistosomiasis control programs,and promoting the intensi-ty of technological innovation to improve the technological level of forestry schistosomiasis control programs.

To observe the patients with type 2 diabetes who were injected premixed insulin analogues after short time continuous subcutaneous insulin infusion( CSII ) treatment.It was found that the patients needed premixed insulin analogue injection 2 times daily when the dosage of CSII was less than 45 U/d,and 3 times daily when the dosage was greater than 45 U/d.The relationship of dosages between premixed insulin analogue treatment ( Y ) and CSII treatment(X) was calculated by following equations:2 times daily premixed insulin analogue treatment:Y =13.093 +0.395X,3 times daily premixed insulin analogue treatment:Y =23.114+0.405X.

Objective: In order to implement effectively on-scene medical response to a nuclear or radiological emergency, and also keep track of relevant on-scene audio and video information and monitoring data, we have designed and developed a monitoring platform for medical response to nuclear or radiological emergency. Methods:Based on relevant national standards for emergency response and the features of nuclear or radiological emergency, exploiting modern information technology and monitoring equipments, we formulate the design idea, characteristics, functions and framework of the platform. This platform takes treatment centers for nuclear or radiological injuries, designated medical institutions and medical response teams as main users. Results:We have developed the monitoring platform for medical response to nuclear or radiological emergency. Conclusion:Through the application of this platform, we hope to enhance the preparedness and on-scene response capability for nuclear or radiological emergency, and also provide information support for disposal of nuclear or radiological emergency in the future.