No abstract available.
Appendicitis* ; Humans

The purpose of this study was to investigate the gaps of bone-acetabular component interface, the initial mechanical stability and the effects of adjuvant screw fixation in the press-fitted two different shaped porous-coated acetabular components. Semi-hemispherical Harris-Galante II cup and full hemispherical Trilogy cup were press-fitted with or without adjuvant screw fixation in 40 bovine femur. The gaps of bone-implant interface were measured in each radiography of all specimen and axial compression tests and rotational stability tests were performed using servohydraulic tension-compression machine. There was significantly smaller gap at polar 1/3 region in the specimen implanted with Trilogy cup. But the adjuvant screw fixation did not affect the amount of gap. There was no significant statistical difference in axial load and rotational stability test in each situations of fixation. This study demonstrates that the initial mechanical stability is not influenced by the shape of semi-hemispherical Harris-Galante II cup and full hemispherical Trilogy cup and also independent of adjuvant screw fixation. But smaller gap of Trilogy cup at the polar 1/3 region indicates the possibility that less amout of wear debris of polyethylene or metal will be deposited and therefore less osteolysis or cup loosening will occur, but this hypothesis should be confirmed by the long-term clinical follow-up.
Acetabulum* ; Arthroplasty, Replacement, Hip* ; Femur ; Follow-Up Studies ; Osteolysis ; Polyethylene ; Radiography

No abstract available.
Constriction, Pathologic* ; Neurologic Manifestations* ; Spinal Canal*

PURPOSE: Upper urinary tract diseases are major factors increasing morbidity and mortality in patients with spinal cord injuries. A video urodynamic study is one of the best methods for detecting neuro-urologic functional impairment in such patients. Therefore, the risk factors of upper urinary tract diseases were evaluated in patients with a spinal cord injury undergoing video urodynamics. MATERIALS AND METHODS: The subjects were 161 spinal cord injured patients with voiding difficulty. The patients were divided into 2 groups, on the basis of the presence of upper urinary tract diseases, and compared according to various objective factors. In addition, the neurogenic bladder dysfunction was classified according to the anatomical level of the spinal cord injury. RESULTS: Of the 161 patients, 13 developed upper urinary tract diseases. When those patients with and without upper urinary tract diseases (complicated and normal groups, respectively) were compared, the rates of patients with chronic urethral or suprapubic catheterization, upper motor neuron injury, quadriplegia, complete injury and low compliance were higher in the complicated than the normal group. There was also an increasing rate of the prevalence of detrusor areflexia in lower motor neuron lesions. The patients with detrusor hyperreflexia, accompanied by detrusor-sphincter dyssynergia, mostly had a cervical cord injury. CONCLUSIONS: Chronic urethral or suprapubic catheterization, upper motor neuron injury, complete injury with quadriplegia, and low compliance are thought to be risk factors for inducing upper tract diseases in spinal cord injury patients. Thus, patients exposed to these factors should be monitored through video urodynamics and radiologic evaluation for the prevention and early detection of upper urinary tract diseases.
Ataxia ; Catheterization ; Catheters ; Compliance ; Humans ; Mortality ; Motor Neurons ; Prevalence ; Quadriplegia ; Reflex, Abnormal ; Risk Factors* ; Spinal Cord Injuries ; Spinal Cord* ; Urinary Bladder, Neurogenic ; Urinary Tract* ; Urodynamics* ; Urologic Diseases*

No abstract available.
Lung Neoplasms* ; Lung* ; Muscle, Skeletal* ; Neoplasm Metastasis*

PURPOSE: To determine the prognostic and predictive value of liver volume in colorectal cancer patients with unresectable liver metastases. MATERIALS AND METHODS: Sixteen patients received whole liver radiotherapy (WLRT) between January 1997 and June 2013. A total dose of 21 Gy was delivered in 7 fractions. RESULTS: The median survival time after WLRT was 9 weeks. In univariate analysis, performance status, serum albumin and total bilirubin level, liver volume and extrahepatic metastases were associated with survival. The mean liver volume was significantly different between subgroups with and without pain relief (3,097 and 4,739 mL, respectively; p = 0.002). CONCLUSION: A larger liver volume is a poor prognostic factor for survival and also a negative predictive factor for response to WLRT. If patients who are referred for WLRT have large liver volume, they should be informed of the poor prognosis and should be closely observed during and after WLRT.
Bilirubin ; Colorectal Neoplasms* ; Humans ; Liver* ; Neoplasm Metastasis* ; Prognosis ; Radiotherapy ; Serum Albumin ; Tumor Burden

Mitochondrial DNA (mt DNA) and the non-recombining region of the Y chromosome are passed down, unaltered, from generation to generation, matrilineally and patrilineally, respectively. Therefore, the Y-chromosome DNA and mtDNA are known as lineage markers, and they play important roles in studies based on human migration and evolutionary history. Y-chromosome DNA is used in forensic analysis to identify individuals involved in cases of sexual assault. In this paper, we review the methods of statistical evaluation of lineage markers used in forensic identification. We also review the combined approach of autosomal and lineage marker evidence.
DNA ; DNA, Mitochondrial ; Human Migration ; Y Chromosome

Avulsion injury of the flexor digitorum profundus tendon from distal phalanx is considered as a rare injury. Accrording to the classification by Leddy and Pacter, this case is Type III, which is a large bony fragment retained by the tendon. The distal pulley prevents retraction beyond the middle phalanx. We are reporting a case with brief review of literatures.
Classification ; Tendon Injuries ; Tendons

BACKGROUND: EGF and TGF-a are ligands for the EGF-receptor and act as mitogens for a variety of tissues. TGF-a, in particular, has been implicated as an autocrine growth factor for several cancer cell lines. TGF-B exerts an inhibitory effect on the growth of most epithelial cell types, and the loss of responsiveness to this growth inhibition has been implicated in the development of a variety of human cancers. In the present study, we evaluate whether EGF, TGF-a and TGF-B modulate apoptosis and cell cycle progression in cervical cancer cell lines. MATERIALS & METHODS: The effect of EGF, TGF-a and TGF-B on apoptosis and cell cycle such as CaSki and HeLa cell lines was analysed by flow cytometry RESULTS: 1. TGF-B did not induce apoptosis in CaSki and HeLa cell lines. 2. TGF-B as well as EGF, TGF-a, did not affect the process of apoptosis significantly. 3. The time to occur apoptosis was different between CaSki and HeLa cells treated by growth factots. 4. G1 phase was the checkpoint in CaSki and HeLa cells treated with TGF-B. CONCLUSION: These results suggest that TGF-B as well as EGF, TGF-a does not induce apoptosis and cell growth inhibition.
Apoptosis* ; Cell Cycle Checkpoints* ; Cell Cycle* ; Cell Line* ; Epidermal Growth Factor* ; Epithelial Cells ; Flow Cytometry ; G1 Phase ; HeLa Cells ; Humans ; Ligands ; Mitogens ; Uterine Cervical Neoplasms*

Cryptococcus is native to the environment and thrives in any type of environment inhabited by birds. Cryptococcal genito-urinary infection has been reported in immunnocompromised patients and can involve the adrenal gland, kidney, prostate, or penis. To our knowledge, there have been no reports of cases where cryptococcal epididymo-orchitis infects an uncompromised healthy host. Here, we report a case of primary cryptococcal epididymo-orchitis in a healthy male.
Adrenal Glands ; Birds ; Cryptococcus ; Humans ; Kidney ; Male ; Orchitis ; Penis ; Prostate