1.Changes in Knowledge about AIDS, Attitude toward AIDS Patients and Intention to Use Condoms after AIDS Education.
Soon Bok CHANG ; Hee Sun KANG ; Su Rin SHIN ; Hyun Ju CHAE
Journal of Korean Academy of Community Health Nursing 2006;17(3):397-406
No abstract available.
Condoms*
;
Education*
;
Humans
;
Intention*
2.Two Cases of Acute Renal Failure Associated with Non-fulminant Acute Hepatitis A.
Sung Eun KIM ; Soo Jin KIM ; Hyoung Su KIM ; Hee Sun KIM ; Eun Sook NAM ; Sang Kyu LEE ; Su Rin SHIN ; Hak Yang KIM
The Korean Journal of Gastroenterology 2006;48(6):421-426
Hepatitis A is generally regarded as a mild, self-limiting disease of the liver. Acute renal failure has rarely been reported in association with non-fulminant acute hepatitis A. Acute tubular necrosis is the most common form of renal injury in such patients. We recently experienced two cases of hepatitis A in which acute renal failure occurred early in the course of the illness and had a clinical course suggestive of acute tubular necrosis. In both patients, the clinical course of renal dysfunction was almost parallel to that of hepatic dysfunction. Hemodialysis was performed in patient 1 because of severe uremia despite maintaining urine output more than 2,000 mL per day. On the other hand, hemodialysis was not performed in patient 2 who showed a rapid recovery of renal dysfunction. The renal biopsy of patient 1 demonstrated typical findings of acute tubular necrosis on microscopy.
Acute Disease
;
Adult
;
Hepatitis A/complications/*diagnosis/pathology
;
Humans
;
Kidney Failure, Acute/complications/*diagnosis/pathology
;
Male
;
Renal Dialysis/methods
3.A Case of Breast Cancer in a Male Patient with Cryptogenic Cirrhosis.
Su Rin SHIN ; Myung Seok LEE ; Sang Hoon PARK ; Jong Soo CHOI ; Kyung Min LEE ; Jin Bae KIM ; Hyeong Su KIM ; Jeong Won KIM
The Korean Journal of Gastroenterology 2012;60(3):182-185
Breast cancer is a rare disease in men. We report a case of 53-year-old obese male, with known cryptogenic cirrhosis and hepatocellular carcinoma, presenting a tender mass on left breast. He was diagnosed with invasive intraductal carcinoma, which was consistent with a sporadic lesion. On the basis of previous literatures, obesity can be regarded as a cause for breast cancer even in men. However, there has been inconsistent data about link between liver cirrhosis and male breast cancer, which can be due to heterogenity in the etiology of cirrhosis. Through this case, it can be postulated that the risk for male breast cancer may vary according to the etiology of cirrhosis.
Breast Neoplasms, Male/*etiology/secondary/ultrasonography
;
Carcinoma, Hepatocellular/diagnosis/pathology
;
Humans
;
Immunohistochemistry
;
Liver Cirrhosis/complications/*diagnosis/pathology
;
Liver Neoplasms/diagnosis/pathology
;
Male
;
Middle Aged
;
Receptors, Estrogen/metabolism
;
Tomography, X-Ray Computed
4.A Case of Nonpolypoid Cancer Arising from Colonic Muco-submucosal Elongated Polyp.
Yunho SHIN ; Jin Bae KIM ; Jong Soo CHOI ; Kyung Min LEE ; Su Rin SHIN ; Sang Hoon PARK ; Jeong Won KIM ; Myung Seok LEE
The Korean Journal of Gastroenterology 2012;59(3):257-259
A colonic muco-submucosal elongated polyp (CMSEP) was identified at colonoscopy in a 53-year-old male patient with lower gastrointestinal bleeding. Non-polypoid depressed type of early cancer was noted at the tip of the colonic polyp. The CMSEP is very rare and incidentally found in most cases. Moreover, its association with colonic neoplasia is extremely rare. To our knowledge, this is the second case report of CMSEP associated with a cancerous transformation.
Colonic Neoplasms/*diagnosis/pathology
;
Colonic Polyps/*pathology
;
Colonoscopy
;
Gastrointestinal Hemorrhage
;
Humans
;
Intestinal Mucosa/*pathology
;
Male
;
Middle Aged
5.A Case of Intraperitoneal Immunoglobulin G4-related Inflammatory Pseudotumor.
In Ho MOH ; Jin Bae KIM ; Su Rin SHIN ; Sung Won JUNG ; Sang Hoon PARK ; Jeong Won KIM ; Mi Kyung SHIN ; Myung Seok LEE
The Korean Journal of Gastroenterology 2012;60(4):258-261
The term inflammatory pseudotumor (IPT) has been used to describe inflammatory and fibrosing tumoral processes of an undetermined cause that may involve a variety of organ system. IgG4-related disease is a newly recognized fibroinflammatory condition characterized by IgG4-producing plasma cell expansion in affected organs and, often but not always, elevated serum IgG4 concentrations. IgG4-related IPTs, a subtype of IPT, are characterized by dense infiltration of IgG4-positive plasma cells and stromal fibrosis. The association between inflammatory pseudotumor and IgG4 was first reported with a regard to sclerosing pancreatitis. Despite there are many reports on intraperitoneal IPTs including both cellular and lymphoplasmacytic type, only a few cases have been confirmed to be IgG4-related. We experienced a case of intraperitoneal IgG4-related inflammatory pseudotumor in an 83-year-old woman presenting with epigastric pain and malaise. Surgical specimens revealed an IgG4-related inflammatory pseudotumor.
Aged, 80 and over
;
C-Reactive Protein/analysis
;
Female
;
Granuloma, Plasma Cell/*diagnosis/pathology/surgery
;
Humans
;
Immunoglobulin G/*blood
;
Plasma Cells/metabolism
;
Positron-Emission Tomography
;
Tomography, X-Ray Computed
6.A Case of Intraperitoneal Immunoglobulin G4-related Inflammatory Pseudotumor.
In Ho MOH ; Jin Bae KIM ; Su Rin SHIN ; Sung Won JUNG ; Sang Hoon PARK ; Jeong Won KIM ; Mi Kyung SHIN ; Myung Seok LEE
The Korean Journal of Gastroenterology 2012;60(4):258-261
The term inflammatory pseudotumor (IPT) has been used to describe inflammatory and fibrosing tumoral processes of an undetermined cause that may involve a variety of organ system. IgG4-related disease is a newly recognized fibroinflammatory condition characterized by IgG4-producing plasma cell expansion in affected organs and, often but not always, elevated serum IgG4 concentrations. IgG4-related IPTs, a subtype of IPT, are characterized by dense infiltration of IgG4-positive plasma cells and stromal fibrosis. The association between inflammatory pseudotumor and IgG4 was first reported with a regard to sclerosing pancreatitis. Despite there are many reports on intraperitoneal IPTs including both cellular and lymphoplasmacytic type, only a few cases have been confirmed to be IgG4-related. We experienced a case of intraperitoneal IgG4-related inflammatory pseudotumor in an 83-year-old woman presenting with epigastric pain and malaise. Surgical specimens revealed an IgG4-related inflammatory pseudotumor.
Aged, 80 and over
;
C-Reactive Protein/analysis
;
Female
;
Granuloma, Plasma Cell/*diagnosis/pathology/surgery
;
Humans
;
Immunoglobulin G/*blood
;
Plasma Cells/metabolism
;
Positron-Emission Tomography
;
Tomography, X-Ray Computed
7.PCL/β-TCP Composite Scaffolds Exhibit Positive Osteogenic Differentiation with Mechanical Stimulation.
So Hee PARK ; Su A PARK ; Yun Gyeong KANG ; Ji Won SHIN ; Young Shik PARK ; Seo Rin GU ; Yan Ru WU ; Jie WEI ; Jung Woog SHIN
Tissue Engineering and Regenerative Medicine 2017;14(4):349-358
We investigated the use of Polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) composites with applied mechanical stimulation as scaffold for bone tissue engineering. PCL-based three-dimensional (3D) structures were fabricated in a solvent-free process using a 3D-printing technique. The mass fraction of β-TCP was varied in the range 0–30%, and the structure and compressive modulus of the specimens was characterized. The shape and interconnectivity of the pores was found to be satisfactory, and the compressive modulus of the specimens was comparable with that of human trabecular bone. Human mesenchymal stem cells were seeded on the composites, and various biological evaluations were performed over 9 days. With a mass fraction of β-TCP of 30%, differentiation began earlier; however, the cell proliferation rate was lower. Through the use of mechanical stimulation, however, the proliferation rate recovered, and was comparable with that of the other groups. This stimulation effect was also observed in ECM generation and other biological assays. With mechanical stimulation, expression of osteogenic markers was lower on samples with a β-TCP content of 10 wt% than without β-TCP; however, with mechanical stimulation, the sample with a β-TCP content of 30 wt% exhibited significantly greater expression of those markers than the other samples. We found that mechanical stimulation and the addition of β-TCP interacted closely, and that a mass fraction of β-TCP of 30% was particularly useful as a bone tissue scaffold when accompanied by mechanical stimulation.
Biological Assay
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Bone and Bones
;
Cell Proliferation
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Humans
;
Mesenchymal Stromal Cells
8.A bleeding by colonic invasion of chest wall metastasis of hepatocellular carcinoma after RFA.
Su Rin SHIN ; Myoung Kuk JANG ; Jung Hye KWON ; Eun Sook NAM ; Ji Sun JANG ; Sang Kyu LEE ; Hwan Chang KIM
Korean Journal of Medicine 2006;70(5):559-563
Radiofrequency ablation (RFA) has been widely used for treating localized hepatocellular carcinoma (HCC). Metastasis to the chest wall through the tract during performing RFA may occur uncommonly. However, it is extremely rare that massive hematochezia occurs by colonic invasion of metastatic focus on chest wall. A 48-year-old man was presented with approximately 500 cc of hematochezia. He was diagnosed as having HCC 6 years ago, and underwent RFA 3 times over a period of 5 years. Twelve months ago, right lobectomy was done on recurred lesion. 5 months ago, HCC recurred through invasion to the chest wall involving the right 5th rib, but there have been no recurrent tumor masses on the liver on CT until admission. Emergent colonoscopy demonstrated a 3 x 3 cm sized extrinsic mass on proximal transverse colon that had a blood clot. Pathology from colonic mass revealed pseudoglandular type of HCC.
Carcinoma, Hepatocellular*
;
Catheter Ablation
;
Colon*
;
Colon, Transverse
;
Colonoscopy
;
Gastrointestinal Hemorrhage
;
Hemorrhage*
;
Humans
;
Liver
;
Middle Aged
;
Neoplasm Metastasis*
;
Pathology
;
Ribs
;
Thoracic Wall*
;
Thorax*
9.Two cases of acute fulminant myocarditis supported by extracorporeal membrane oxygenation.
Su Bum PARK ; Hong Ryul JUNG ; Ha Rin RHEE ; Tae Kyung KIM ; Han Cheol LEE ; Taek Jong HONG ; Yung Woo SHIN
Korean Journal of Medicine 2009;77(Suppl 1):S87-S92
Myocarditis is defined as inflammation of the myocardium caused by viral, richettsial, bacterial, or protozoal infection, or drug toxicity. The clinical course of patients with myocarditis varies from subclinical disease to fulminant myocarditis (FM). FM occurs rapidly and causes heart failure or lethal arrhythmia, often leading to death by cardiogenic shock due to severe left ventricular dysfunction. For some critical patients who have difficulty maintaining hemodynamic status, percutaneous cardiopulmonary support, extracorporeal membrane oxygenation (ECMO), and/or a mechanical ventricular assist device are available alternative choices. Here we report cases of patients with FM who were treated using ECMO during the acute stages of the illness.
Arrhythmias, Cardiac
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Drug Toxicity
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Extracorporeal Membrane Oxygenation
;
Heart Failure
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Heart-Assist Devices
;
Hemodynamics
;
Humans
;
Inflammation
;
Myocarditis
;
Myocardium
;
Shock, Cardiogenic
;
Ventricular Dysfunction, Left
10.Antiviral Therapy in Patients after Treatment for Hepatitis C-Related Hepatocellular Carcinoma.
Su Rin SHIN ; Seung Woon PAIK ; Geum Youn GWAK ; Moon Seok CHOI ; Joon Hyoek LEE ; Kwang Cheol KOH ; Byung Chul YOO
Gut and Liver 2011;5(1):77-81
BACKGROUND/AIMS: Despite great progress, antiviral treatment for chronic hepatitis C in patients with prior hepatocellular carcinoma (HCC) has been rarely investigated. We evaluated the efficacy and safety of antiviral therapy following treatment for hepatitis C-related HCC. METHODS: Thirteen patients (age 34 to 60 years) who were treated with peginterferon plus ribavirin after treatment for HCC were reviewed. RESULTS: There were 6 patients with genotype 1 and 7 patients with genotype 2. All patients showed advanced fibrosis (> or =F3) but belonged to the Child-Pugh class A. Treatment was stopped in 2 patients because of recurrent HCC and in 1 patient due to a lack of early virologic response. Seven patients achieved sustained virologic response and three patients relapsed. The sustained virologic response rate was 54% overall, 17% in genotype 1, and 86% in genotype 2. No significant adverse events were reported. CONCLUSIONS: Antiviral therapy should not be excluded in patients who were previously treated with HCC with genotype 2 chronic hepatitis C, in which an efficacious antiviral treatment for chronic hepatitis C was feasible. Additional study is needed to prove the validity of antiviral therapy in patients with genotype 1 hepatitis C-related HCC.
Carcinoma, Hepatocellular
;
Fibrosis
;
Genotype
;
Hepatitis
;
Hepatitis C, Chronic
;
Humans
;
Ribavirin