No abstract available.
Cholangiocarcinoma*

No abstract available.
Transplants*

PURPOSE: To evaluate the characteristic CT findings of neuroblastoma, we studied neurobalstomas. METHODS AND MATERIALS: We analysed CT findings of available 25 cases among pathologically proved 51 neurobalstomas from Jan. 1983 to Sept. 1990. RESULTS: The most frequent site of origin is adrenl gland (40%) and the second is retroperitoneum (32%) and the third ismediastinum (16%). Characteristic CT findings are as follows:Calcifications within the tumor is detected in 86% of abdominal neuroblastomas and 50% of mediastinal origin. Hemorrhagic and necrotic changes within the tumor is noted at 86% in the tumor of abdominal origin and 25% in mediastinal neuroblastomas. Contrast enhanced study showed frequently septated enhanced appearance with/without solid contrast enhancement. Encasements of major great vessels such as aorta and IVC with/without displacement by metastatic lymphnodes or tumor are frequently seen in 90% of abdominal neuroblastomas. Multiple lymphadenopathy are detected in 95% of abdominal neurobalstomas and 25% of mediastinal neuroblastomas. The most common organ of contiguous direct invasion is kidney in 6 cases and the next one is liver but intraspinal canal invasion is also noted in 2 cases. CONCLUSION: We concluded that diagnosis of neuroblastoma would be easily obtained in masses of pediatric group from recognition of above characteristic findings.
Aorta ; Diagnosis ; Kidney ; Liver ; Lymphatic Diseases ; Neuroblastoma*

No abstract available.
Dopaminergic Neurons* ; Retina*

No abstract available.
Dopaminergic Neurons* ; Retina* ; Rodentia*

We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief review of the related literature was made on this subject.
Anemia ; Animals ; Cats ; Child, Preschool ; Cough ; Diagnosis ; Dyspnea ; Hemangioma ; Humans ; Kasabach-Merritt Syndrome* ; Male ; Teratoma ; Thorax ; Thrombocytopenia

We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief of the related literature was made on this subject.
Animals ; Cats ; Child, Preschool ; Cough ; Diagnosis ; Dyspnea ; Humans ; Male ; Teratoma* ; Thorax

OBJECTIVE: To evaluate factor XII deficiency in patients with recurrent spontaneous abortion and its relation to aPTT. MATERIAL AND METHOD: Factor XII was analyzed by clotting method. RESULTS: Of 70 patients with recurrent spontaneous abortion, there were 35 cases of factor XII deficiency. Among them, there were only 3 cases of prolonged aPTT. CONCLUSIONS: It is still unclear whether factor XII deficiency is related to recurrent spontaneous abortion. Molecular approaches should be used to understand further the causal relationship. But based on this result, in the workup of patients with recurrent spontaneous abortion, factor XII should be included. aPTT is not likely to represent the abnormality of factor XII.
Abortion, Spontaneous* ; Factor XII Deficiency* ; Factor XII* ; Female ; Humans ; Pregnancy

Diabetic retinopathy is characterized by the pericyte loss, microaneurysms and neovascularization eventually leads to blindness. The present study was examined changes of the microvasculature histochemically and immunochemically in the diabetic rat retina previously documented neuronal alterations, in order to verify the usefulness of the animal model of diabetes for the pathophysiology of angiogenesis. Diabetic condition was induced by a single intravenous injection of streptozotocin in Sprague-Dawley rats aged of 8weeks. The animals showing high blood glucose levels (above 300 mg/dL) were cared for 1, 4, 8, and 12 weeks, respectively. The retinas were processed for Griffonia simplicifolia isolection (GSI) B4 histochmistry, and anti-alpha-smooth muscle actin (alpha-SMA) and anti-NG2 immunochemical techniques. The retinal vasculature was well demarcated by endothelial profiles with GSIB4 histochemistry. alpha-SMA immunoreactivity appeared in the arterioles and the primary capillaries, and NG2 in the arterioles and the whole capillary beds. Changes evoked by diabetes were largely occurred in the capillary. Compared to the retina at normal state, the capillary networks were more complicated, enlarged, and dense. NG2 reactivity was reduced especially under the cytoplasmic processes of the pericytes. In the near periphery of the capillary mainly in the ganglion cell layer of the diabetes, GSIB4 reactive microglia were distributed. These results suggest that the retinal microvasculature showed the precedent events of neovascularization due to diabetes and rat model of diabetes is useful for study of neovascularization mechanism of the diabetic retinopathy.
Actins ; Aged ; Animals ; Arterioles ; Blindness ; Blood Glucose ; Capillaries ; Cytoplasm ; Diabetic Retinopathy ; Ganglion Cysts ; Griffonia ; Humans ; Immunochemistry ; Injections, Intravenous ; Microglia ; Microvessels ; Models, Animal ; Muscles ; Neurons ; Pericytes ; Rats ; Rats, Sprague-Dawley ; Retina ; Retinaldehyde ; Streptozocin

An attempt has been made to discriminate synaptic diversity in the neostriatum of the cat with emphasis on the characteristic structures of axon terminals and postsynaptic profiles. The differentiation of the axon terminals was based on the size and shape of synaptic vesicles in the axoplasm. Three types of axon terminals could be differentiated: Type I, the terminals contained small round (45 nm in diameter) vesicles; type II, the terminals with large pleomorphic (50 nm) vesicles; and type III, the terminals contained flattened (45 x 25 nm) vesicles. The type I terminals were making asymmetrical or symmetrical synapses in contact with the somata, dendrites and dendritic spines of neurons in the neostriatum, and a few type I terminals making asymmetrical or symmetrical contact with axons were also observed. The type II and III terminals were making symmetrical contact with the somata and dendrites of neostriatal neurons. A few type II terminals formed at the node of Ranvier of myelinated nerve fibers were making symmetrical contact with large dendrites. Additionally, dendro-dendritic and serial syanpses were rarely found in the neostriatum. In the serial synapses composed of axo-dendritic and dendro-dendritic synapses, the type I terminals making asymmetrical contact and the type II making symmetrical contact were identified.
Animals ; Axons ; Cats* ; Dendrites ; Dendritic Spines ; Neostriatum* ; Nerve Fibers, Myelinated ; Neurons ; Presynaptic Terminals ; Synapses ; Synaptic Vesicles