Congresses as Topic ; Humans ; Hypersensitivity, Immediate ; immunology ; Rhinitis ; immunology

Thyroid hormones (TH) play an imp or tant role in the development and maturity of the mammalian brain. Maternal TH de ficiency, even subclinical hypothyroidism, leads to poor neurodevelopment of the fetus. Screening of pregnant women for hypothyroidism is recommended. Identific ation of the TH-responsive genes in the developing brain and investigation on t heir functions are helpful to provide insights into the molecular mechanisms by which TH influence brain development.

Objective To observe any changes in spinal cord hemodynamics after spinal cord injury and to investigate their mechanism. Methods Twenty female Sprague-Dawley rats were divided into a control group and a moderate injury group,10 rats in each group.A rat model of spinal cord injury caused by moderate compression was established using Nystrom's method.Changes in the velocity and volume of blood flow and in the diameters of vessels of the spinal cord were monitored for 6 hours using laser speckle imaging. Results No changes in the velocity or volume of blood flow or in the diameter of vessels were observed in the control group,but all of these indices diminished significantly in the injury group. Conclusions Laser speckle imaging can be used to monitor changes in spinal cord hemodynamics.Such changes after acute spinal cord injury indicate progressive post-injury ischemia.The occlusion of veins may be an important contributor to post-injury ischemia.

Objective To know about the state of the elderly' health and their family function and their relationship in the pension institutions so as to provide the basis of promoting the eldedy' health status for the nurses in the pension institutions.Methods Two hundred and sixty elderly were investigated according to their perceived health status and family function with self-rated health measurement scale and APGER in the pension institutions in Hengyang city,and data were analyzed.Results The average selfrated health score of the elderly in pension institutions was (243.95±64.13),accounted for 55.44% of the total.The score of family function was (5.64±2.57),accounted for 56.40% of the total.The score of dimensions of family function was positively correlated with the total score of self-rated health score,mental health and social health.Conclusions The total score of self-rated health score of the elderly in pension institutions is a little lower.A majority of the elderly has different levels of family function disorder,the effect of family function on the elderly' s mental health and social health is bigger than that of the elderly' s physical health.

Objective:To assess the proportion of genotypes of osteocalcin gene polymorphism, and to investigate if the polymorphism of osteocalcin gene is associated with BMD in Chinese premenarche girls. Methods: 152 healthy premenarche girls of Han ethic (9-11.5y) were recruited. BMD and BMC at the lumber spine (L1-L4), proximal femur, and total body were measured by DXA; PCR-RFLP was used to amplify the polymorphisms of the osteocalcin gene. Results:The proportion of genotype of OC gene polymorphism were 5.26% HH,, 36.84% Hh, and 58.90% hh, respectively. Significant differences were observed in BMD and BMC at the total body, and BMD at the L1-L4 lumber spine and femur neck among subjects with different genotypes (P

Objective To determine the changes of coagulation indexes of rabbits struck at different levels and sieve the traditional coagulation indexes, such as activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT) and fibrinogen (FIB). Methods We used correlation analysis to precondition the data to reject indexes, and used stepwise discriminatory analysis to choose indexes and made the diagnosis by multiple linear discrimination analysis. Then, by random sampling we compared the correct diagnostic rate by 4 indexes with that by 3 indexes. Results The correct discrimination rate of blood coagulation function diagnosis in rabbits was up to 87.60% by the four indexes and 96.12% with the three indexes (APTT, PT and TT). The average correct discrimination rate of blood coagulation function diagnosis in 1 000-time random sampling was up to 83.07% by the four indexes and 85.16% by the three indexes. Conclusion Stepwise discriminatory analysis can be used to discriminate hemorrhage from thromboxane. The correct diagnostic rate gets higher when FIB was rejected.

Objective:To investigate the characteristics of calcium metabolism and identify the calcium intake that produces plateau retention in premenarche Chinese girls. Method:Forty-nine healthy premenarche Chinese girls (9-11.5 y) were recruited, and divided into four groups respectively receiving one of four different doses of calcium intakes for 6 d, 600 mg (usual diet),900 mg (containing 250 ml milk),1 200 mg (containing 250 ml milk and 750 mg CaCO3) and 1 500 mg calcium (250 ml milk and 1500 mg CaCO3) per day. Calium in 3-day urine and stool,and 3-d duplicated food samples were collected to assess the calcium equilibrium during the treatment period. Results: There were no significant differences in apparent calcium absorption among the four groups (55%, 53%, 52% and 52%). The relationship between calcium intake and calcium retention was fitted into a non-liner regression model which showed that the calcium retention was approaching the plateau when calcium intake reached 1100mg/d. Conclusion: The apparent calcium absorption was 53%?0.12% in Chinese premenarche girls with dietary calcium intakes ranged between 600 to 1500 mg/d. Calcium retention approached its plateau when calcium intake reached 1 100 mg/d in Chinese premenarche girls.

Objective:To explore the clinical features of subtyp es of ADHD in DSM-Ⅳ.Method:126 children fulfilled ADHD criteria of D S M-Ⅳ were further divided into 3 subtypes:predominantly inattentive(PI,61 cases) , predominantly hyperactive-impulsive(HI,9 cases)and combined type(CT,56 cases).C om orbid mental disorders were compared among the three groups.Parents and teacher s of children in each group completed CBCL(child behavior checklist)and TRF(teach er's report form).CWISC(Wechsler intelligence scale for children,Chinese versio n )and attention tests were also applied in each group.Results:Childr e n in CT group had more conduct disorder,more externalizing,delinquent and aggres sive behaviors rating by parents and teachers,and more inattentive than children in PI group.School performance of children in PI group was better than that of the other two groups evaluated by teachers.Conclusion:ADHD CT subty pe had highest rate of comorbid conduct disorder.They have more externalizing b ehavior,more academic problems and more inattentive.This subtype may be the mos t impaired subtype.

Objective: To develop the norm of Piers-Harris Children's Self-concept Scale (PHCSS) in Chinese urban children and test the reliability and validity. Method: A total of 1698 children with the mean age 12?3 year-old (846 boys and 852 girls) from 20 cities in China completed the scale. Results: The test-retest reliability, split-half and Crobach were in 0.695～0.858, the correlation between each item score and total score were in 0.078～0.467, showed better item differentiation except for 3 items. The validity was perfect, represented by significant correlation (r=0.051～0.353) between the score and Conners Parent Symptom Questionnaire and Teacher Rating Scale. Conclusion: The results demonstrate the scale are suitable for demands of psychometrics and applicable in Chinese children.