1.Changes in HO-1, HSP70 and iNOS Expressions in the Rat Liver after Remote Ischemic Preconditioning.
Su Kyung JEON ; Youn Kyoung SEO ; Doo Jin PAIK
Korean Journal of Physical Anthropology 2012;25(4):167-175
Ischemic preconditioning (IP), short pre-treatment sublethal ischemia, induces a state of protection against subsequent prolonged ischemia-reperfusion. The purpose of this study was to investigate the expression of HO-1, HSP70, and iNOS proteins in the liver subjected to the courses of reperfusion after repetitive cycles of remote IP in the rat. Using thirty five week-old rats, the remote preconditioning was undertaken by vascular clamp occlusion of blood flow to one hindlimb, with 3 and 10 cycles of 5 minutes occlusion followed by 5 minutes reperfusion. The liver was removed 0, 3, 6, 24, and 72 hours of reperfusion after remote IP and assayed by immunohistochemical staining and Western blotting analyses for anti-HO-1, anti-HSP70, and anti-iNOS antibodies. The expression of HO-1 in rat liver increased at 72 hours of reperfusion groups after 3 and 10 cycles of remote IP, compared with normal control groups. The expression of HSP70 in rat liver increased at 6 hours of reperfusion groups after 3 cycles of remote IP, compared with normal control groups. The expression of HSP70 in rat liver increased at 0 hour of reperfusion groups after 10 cycles of remote IP, compared with normal control groups and decreased at 24 and 72 hours of reperfusion groups. The expression of iNOS in rat liver increased at 24 hours of reperfusion groups, but decreased at 72 hours of reperfusion groups after 3 and 10 cycles of remote IP, compared with normal control groups. In summary, these results showed that at early phase of reperfusion after remote IP, HSP70 expression was increased in rat liver. However, at 72 hrs of reperfusion after remote IP, HO-1 expression was increased and iNOS expression was decreased in rat liver.
Animals
;
Blotting, Western
;
Hindlimb
;
Ischemia
;
Ischemic Preconditioning
;
Liver
;
Proteins
;
Rats
;
Reperfusion
2.A Case of an Anesthesia for an Emergency Cesarean Section in a Patient with an Aortic Dissection.
Korean Journal of Anesthesiology 2002;43(4):511-514
We experienced a case of a cesarean section of a 32-year-old female with an thoracic aortic dissection under general anesthesia. An aortic dissection in pregnancy is rare but a potentially catastrophic occurrence. There is a poor prognosis if an aortic dissection occurs in pregnancy in the third trimester. The importance in anesthetic management of these patients should prevent any hypertension in response to intubation and surgery with appropriate preoperative care and monitoring.
Adult
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Anesthesia*
;
Anesthesia, General
;
Cesarean Section*
;
Emergencies*
;
Female
;
Humans
;
Hypertension
;
Intubation
;
Pregnancy
;
Pregnancy Trimester, Third
;
Preoperative Care
;
Prognosis
3.A Clinical Significance of Ultrasonography in Transient Synovitis of the Hip
Hyung Ku YOON ; Kwang Pyo JEON ; Kuk Hwan OH ; Dong Jun KIM ; Kyung Su CHA ; Sang Kyu HAN
The Journal of the Korean Orthopaedic Association 1990;25(6):1644-1650
Transient synovitis of the hip is non-specific inflammation and self limited condition, which is most common cause of painful limping in children under 10 years of age. Ultrasonography presents some merits, simple, rapid, non-invasive, low cost, repetitive to assess soft structures in and around the hip joint compared to other diagnostic methods. We prospectively studied 32 cases of unilateral transient synovitis at OPD from Jan. 1988 to Oct. 1989 using 5-7.5 MH, probe ultrasonography. 2-times serial check up in symptomatic and asymptomatic stage about capsule thickness and bone-capsule distance in 3 different positions of the both hips were performed for comparision. The following results were obtained; 1. Boys were 25 cases (78%) and 26 cases (83%) were between 3 and 7 years old of age. 2. Bone-capsule distance in ultrasonography revealed abnormal increase in 72%. 3. External rotation position showed wider bone-capsule distance than other position. 4. Capsule thickness was 3.3mm in diseased and 3.0mm in sound, 0.3mm decrease after treatment. 5. Bone-capsule distance was 4.5mm in symptomatic stage, 2.7mm in asymptomatic stage, 1.8mm decrease after treatment in averge.
Child
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Hip Joint
;
Hip
;
Humans
;
Inflammation
;
Prospective Studies
;
Synovitis
;
Ultrasonography
4.Clinical Study for Lateral Condyle Fracture of Humerus in Children
Hyung Ku YON ; Kwang Pyo JEON ; Kuk Whan OH ; Dae Eun JUNG ; Kyung Hoon KANG ; Min Su YOON
The Journal of the Korean Orthopaedic Association 1994;29(2):415-422
From January 1988 to December 1991, 39 fractures of the lateral condyle of humerus in children were treated at the Department of Orthopaedic Surgery, Sung-Ac General Hospital. It was possible to follow up from one year to four years and eleven months. The authors have analyzed the method of treatment on the basis of the degree of displacement in the change of Carrying angle and Baumann's angle. The results were as follows; 1. Of the 39 cases, the age incidence was confined to 2 to 12 years of age and the average age of the patients were 5 years. 2. Most fractures were Milch type II (29 cases) in contrast to Milch type I (10 cases). 3. According to the initial displacement of the fracture, 8 cases were Jokob's stage I, 21 cases of stage II & 10 cases of stage III. 4. There were no significant difference in the range of change of Carrying angle and Baumann's angle according to initial displacement of fracture site. However, significant difference in outcome were noticed from open reduction and internal fixation in comparison to closed reduction and percutaneous pinning. 5. In all 39 cases, lateral condylar overgrowth (10 cases), cubitus varus (1 cases) and cubitus valgus (3 cases) were noticed as complications but clinical significance was not noted. 6. The above results suggest that internal fixation is recommended for firm fixation although displacement is not severe. In case of Jakob's stage III, anatomical reduction is required in order to reduce additional damage on articular surface and epiphyseal plate caused by excessive manipulation.
Child
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Clinical Study
;
Follow-Up Studies
;
Growth Plate
;
Hospitals, General
;
Humans
;
Humerus
;
Incidence
;
Methods
5.Neonatal Congenital Fibrosarcoma: A Case Report
Hyung Ku YOON ; Kuk Hwan OH ; Kyung Hoon KANG ; Kwang Pyo JEON ; Dae Eun JUNG ; Min Su YOON
The Journal of the Korean Orthopaedic Association 1994;29(5):1357-1361
Congenital fibrosarcoma of neonate is a very rare malignant tumor prone to behave aggressively with a tendency to local recurrence without metastasis. It is characteristically composed of collagenous fibroblasts and herringbone pattern in histology. We experienced a case of congenital fibrosarcoma on the left thigh and report this case with some review in literature with 1½ year follow up.
Collagen
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Fibroblasts
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Fibrosarcoma
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Follow-Up Studies
;
Humans
;
Infant, Newborn
;
Neoplasm Metastasis
;
Recurrence
;
Thigh
6.Relationship of Sexual Attitude, Sexual Identity and Sexual Permissiveness in Junior High School Girls.
Kyung Hee KIM ; Mi Soon JEON ; Su Kang KIM
Journal of Korean Academy of Fundamental Nursing 2004;11(3):353-360
PURPOSE: This study was to identify the relationship betweem sexual attitude, sexual identity, sexual permissiveness in girls in junior high school. METHOD: The participants were 587 female students in Chungnam Province. Data were collected by questionnaire surveys using convenience sampling. The instruments were the Sexual Attitude Scale by Kim (1997), the Sexual Identity Scale by Jung (1990), and the Sexual Permissiveness Scale developed by Reiss (1964). Data were analyzed by the SPSS 11.0 program, using descriptive statistics, Pearson correlation coefficients, t-test, ANOVA and Tukey's multiple comparison. RESULTS: The relationship between sexual attitude and sexual permissiveness had a positive correlation (r=.440, p-0.000). Sexual identity was positively correlated (r=.180, p=.036; r=.222, p=.014) with both sexual attitude and sexual permissiveness, but maleness was the only positive correlation (r=.258, p=.014) with sexual permissiveness, no sexual specialization was the only characteristic that had a positive correlation (r=.188, p=.046) with sexual attitude. CONCLUSION: These results suggest assessment of these factors and treatment fitted to individual needs are important for correct sexual culture. There should be repeated research on various population groups. Moreover, it is considered necessary to carry out factor-related theoretical researches on several variables related to sex through multilateral literature reviews.
Chungcheongnam-do
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Female*
;
Humans
;
Male
;
Permissiveness*
;
Population Groups
;
Surveys and Questionnaires
7.Diagnosis and treatment of calcaneal fractures by computed tomography.
Seung Gyun CHA ; Won Suck LEE ; Kyung Hoon KIM ; Eung Ju KIM ; Su Young JEON ; Sung Ho KOO
The Journal of the Korean Orthopaedic Association 1993;28(7):2610-2617
No abstract available.
Diagnosis*
8.Effective factor of vaginal birth after cesarean.
Su Jin PARK ; Yong Ho LEE ; Kyoung A KIM ; Sang Ki HONG ; Su Kyung BAEK ; Ho Jun LEE
Korean Journal of Obstetrics and Gynecology 2009;52(1):23-29
OBJECTIVE: The aim of this study is to determine prognostic factor affecting the mode of delivery in women with one previous low transverse cesarean section by comparing success group with failure group in Vaginal birth after cesarean (VBAC). METHODS: In this retrospective study, 79 patients with one previous low transverse cesarean section who attempted vaginal birth at Jeon-Ju Jesus Presbyterian hospital from January 1, 1997 to December 31, 2007. Information was collected and analyzed to see if there is significant difference between success group and failure group in VBAC. and the significance was set at P<0.05. RESULTS: The VBAC success rate turned out to 88.6%. There was one case of uterine rupture which was associated with hypoxic -ischemic encephalopathy in neonate. But, there was no case of the fetal death or mother death. There were significant difference between two groups in gestational age, expected fetal body weight, cervical dilation, Bishop score, thickness of lower uterine segment. CONCLUSION: The prognostic factors on success of VBAC can be aid in deciding the mode of delivery after cesarean section. Patient being chosen under strict indication, can enhance the VBAC trial and success rate.
Cesarean Section
;
Female
;
Fetal Death
;
Fetal Weight
;
Gestational Age
;
Humans
;
Infant, Newborn
;
Lipids
;
Mothers
;
Parturition
;
Pregnancy
;
Protestantism
;
Quaternary Ammonium Compounds
;
Retrospective Studies
;
Uterine Rupture
;
Vaginal Birth after Cesarean
9.CT and MR Findings in Patients with Mild Head Injury.
Mi Sun JUNG ; Won Kyung BAE ; Young Tae JEON ; Young Hwa KIM ; Won Su CHO ; Il Young KIM ; Kyung Suk LEE
Journal of the Korean Radiological Society 1996;35(6):847-853
PURPOSE: To assess the prevalence, lesion sites and characteristics of MR findings in patients with mild head injury and the relationship between MR findings and the postconcussion syndrome. MATERIALS AND METHODS: Our study involved 26 patients with mild head injury (Glasgow Coma Scale, 13 to 15 ; no subsequent deterioration ; loss ofconsciousness < 30 minutes). Prospective CT and MR Imaging was performed and the prevalence rate of abnormalities, sites and characteristics of lesions were evaluated, as well as the relationship between MR findings and the postconcussion syndrome. RESULTS: In 17 of 26 patients(65%) there were abnormal findings on MR, and in 8 of the 26(31%), abnormal findings were seen on CT. Abnormalities consisted of cerebral contusion in nine patients, diffuse axonal injury in six and small thin extracerebral hematomas in nine. MR is more sensitive than CT, especially when the lesion is non-hemorrhagic and is closer to the cranial vault. In 16 patients who wereclinically followed up, the prevalence rate of postconcussion syndrome was higher in those with abnormal MR than in those with normal MRI. CONCLUSION: The greater sensitivity of MR makes it a better indicator than CT for the presence and extent of injuries and thus potentially a better predictor of outcome, even in patients with mildhead injuries. Positive MR findings are an objective predictors for the evaluation of patients with postconcussion syndrome after mild head injury.
Axons
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Coma
;
Contusions
;
Craniocerebral Trauma*
;
Head*
;
Hematoma
;
Humans
;
Magnetic Resonance Imaging
;
Prevalence
;
Prospective Studies
10.A Case of Subacute Infective Endocarditis Caused by Arcanobacterium haemolyticum in a Patient with Mitral Valve Prolapse.
Su Mi CHOI ; Hae Kyung LEE ; Yang Ree KIM ; Kyung Su PARK ; Hui Kyung JEON ; Seok Whan MOON ; Yeon Joon PARK ; Wan Shik SHIN
Infection and Chemotherapy 2007;39(2):104-107
Recently, we experienced a case of subacute infective endocarditis caused by A. haemolyticum on mitral valve prolapse complicated with systemic emboli, which was successfully treated with antibiotics and valve replacement surgery. To our knowledge, this is the first report to address infective endocarditis caused by A. haemolyticum in a immunocompetent patient who had mitral valve prolapse and survived with successful treatment. Greater awareness of this uncommon organism is needed to make an accurate diagnosis and perform a better clinical management in the early stage of the disease. Recommendation for the treatment of septic A. haemolyticum infections has not been established. Therefore, the treatment should be based on clinical experiences and in vitro susceptibility profiles of the individual strain. The site of infection as well as antimicrobial susceptibility profiles should be considered for appropriate antibiotics choice and decision to perform a surgical intervention.
Anti-Bacterial Agents
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Arcanobacterium*
;
Diagnosis
;
Endocarditis*
;
Humans
;
Mitral Valve Prolapse*
;
Mitral Valve*