No abstract available.
Molecular Biology

No abstract available.
Humans ; Inpatients*

No abstract available.
Pulmonary Artery*

This study was attempted to know the recent changes of the patterns of diseases among Korean children living inurban and rural areas. 21,498 sick-children, who admitted to the thirteen general hospitals which located in urban and rural areas during past five years from Jan. 1994 to Dec. 1978, were analysed for this purpose. 13,759 sick-children(64.0%) were male, others were female and the ratio of sex was 1,8 : 1. 13,210 sick-children(61.4%)wers lived in large cities(over 500,000 population), 23.9% and 14.7$ of total sick-shildren were lived in small and medium sized cities(50,000~500,000 population) and rural areas respectively. There was a tendency to increase year by year in total number of sick children who admitted to the hospitals with the various kinds of diseases. The seasonal incidence of diseases was highest in summer, 27.9% of sick-children were admitted during summer season and the next season was fall. According to the classification of dieases in childhood (by WHO), the main diseases of sick-childen admitted at thirteen hopitals in this study were classified as respiratory tract diseases(6,044 cases, 28.1%), infection and parasitic diseases(5,605 cases, 26.1%) and neonatal disease(4,013 cases, 18.1%). Thr major ten leading causes of admission were as follows; pneumonia(13.6%), diarrheas(12.4%), prematurity(8.6%), neonatal jaundice(8.2%), URI(5.2%), bronchiolitis(3.6%), nephritis(3.3%), bacterial meningitis(3.1%), viral hepatitis(2,8%), pleurisy and empyema(2.4%). The characteristic patterns of diseases in each different resident areas were noted as follows; In large city the incidence of diseases such as intussusception, typhoid fever and hyperbilirubinemia were high comparing to other areas unexpectively. The occurrence of Japanese B encephalitis, tetanus neonatorum, poliomyelitis, septicemia, meningitis and tuberculosis were come into notice in rural areas. Diarrheal disease, prematurity, pyelonephritis and pertussis were still common in small and medium sized cities. The leading diseases in each age groups were; in neonatal period, prematurity(34.9%), hyperbilirubinemia(32.9%) and pneumonia(8.0%); in infancy, diarrheal diseases(28.2%), pneumonia(19.6%) and bronchiolitis(12.5%); in preschool period, pneumonia(16.2%), diarrheas(13.4%) and URI(6.8%); in school period, glomerulonephrithis(11.0%), pneumonia(9.7%) and viral hepatitis(8.1%); in adolescence, glomerulonephritis(11.5%), viral hepatitis(10.5%) and pneumonia(7.6%).
Child ; Adolescent ; Male ; Female ; Infant, Newborn ; Child, Preschool ; Humans ; Incidence

No abstract available.
Hematocrit ; Mucocutaneous Lymph Node Syndrome*

The purpose of the study is to minimize the incidence of glaucoma and ocular hypertension caused by using corticosteroids during induction chemotherapy for acute lymphoblastic leukemia in children. We have periodically observed the intraocular pressure and the variation of C / D ratio of two 7 years old boys with chemotherapy in our pediatric department. We observed the increase in intraocular pressure using applanation tonometer, and we managed by beta- blockers, carbonic anhydrase inhibitor and etc. Increased intraocular pressure has been normalized after chemotherapy. The frequency of occurrence of the ocular hypertension and glaucoma can be controlled with the quantity of corticosteroids used.
Adrenal Cortex Hormones ; Carbonic Anhydrases ; Child ; Drug Therapy ; Glaucoma* ; Humans ; Incidence ; Induction Chemotherapy* ; Intraocular Pressure ; Leukemia ; Ocular Hypertension ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*

von Gierke disease (type Ia glycogen storage disease) is an inherited disease associated with accumulation of glycogen in the liver, kidney, intestine and erythrocytes due to the defect of glucose-6-phosphatase activity. Hepatomegaly, doll face, anemia, bleeding tendency and increased susceptability to infection are common features observed during infancy. Hypoglycemia especially fasting hypoglycemia is typical metabolic derangement in this disease, followed by metabolic acidosis, lactic acidemia, hyperlipidemia, hyperuricemia, and platelets dysfunction. We experienced a case of von Gierke disease in 6 month-old boy with doll face, hepatomegaly, fasting hypoglycemia, acidosis, anemia, hyperlipidemia, hyperuricemia, and acetonuria. Diagnosis was confirmed by light- and electron microscopic examination of liver biopsy specimen, which revealed hepatocytes filled with dense pools of glycogen and many lipid droplets. Cornstarch dietary therapy for him had favorable responses showing improvement of hypoglycemia, other metabolic derangements, and regression of hepatomegaly.
Acidosis ; Anemia ; Biopsy ; Diagnosis ; Erythrocytes ; Glucose-6-Phosphatase ; Glycogen ; Glycogen Storage Disease Type I* ; Hemorrhage ; Hepatocytes ; Hepatomegaly ; Humans ; Hyperlipidemias ; Hyperuricemia ; Hypoglycemia ; Infant ; Intestines ; Ketosis ; Kidney ; Liver ; Male ; Starch

von Gierke disease (type Ia glycogen storage disease) is an inherited disease associated with accumulation of glycogen in the liver, kidney, intestine and erythrocytes due to the defect of glucose-6-phosphatase activity. Hepatomegaly, doll face, anemia, bleeding tendency and increased susceptability to infection are common features observed during infancy. Hypoglycemia especially fasting hypoglycemia is typical metabolic derangement in this disease, followed by metabolic acidosis, lactic acidemia, hyperlipidemia, hyperuricemia, and platelets dysfunction. We experienced a case of von Gierke disease in 6 month-old boy with doll face, hepatomegaly, fasting hypoglycemia, acidosis, anemia, hyperlipidemia, hyperuricemia, and acetonuria. Diagnosis was confirmed by light- and electron microscopic examination of liver biopsy specimen, which revealed hepatocytes filled with dense pools of glycogen and many lipid droplets. Cornstarch dietary therapy for him had favorable responses showing improvement of hypoglycemia, other metabolic derangements, and regression of hepatomegaly.
Acidosis ; Anemia ; Biopsy ; Diagnosis ; Erythrocytes ; Glucose-6-Phosphatase ; Glycogen ; Glycogen Storage Disease Type I* ; Hemorrhage ; Hepatocytes ; Hepatomegaly ; Humans ; Hyperlipidemias ; Hyperuricemia ; Hypoglycemia ; Infant ; Intestines ; Ketosis ; Kidney ; Liver ; Male ; Starch

BALT(bronchial associated lymphoid tissue) lymphomas are a distinct subgroup of low-grade B-cell extranodal non-Hodgkin's lymphoma, which are classified as a marginal-zone lymphomas. The majority of the patients are asymptomatic or their pulmonary lesions is often discovered incidentally on a routine chest radiograph. A 50-year-old man was admitted for an the evaluation of cough, dyspnea and fever. His chest CT showed ground glass appearance with interlobular septal thickening in both lower lobes, right middle lobe and left lingular division. He had been initially diagnosed with lipoid pneumonia and was kept under observation. However, his chest lesion showed continuous progression and a video-associated thoracoscopy was performed His pulmonary lesion was confirmed histologically to be a BALT(bronchial associated lymphoid tissue) lymphoma. We report a case of a BALT lymphoma, which was initially misdiagnosed as lipoid pneumonia.
B-Lymphocytes* ; Cough ; Dyspnea ; Fever ; Glass ; Humans ; Lymphoid Tissue* ; Lymphoma ; Lymphoma, B-Cell* ; Lymphoma, Non-Hodgkin ; Middle Aged ; Pneumonia* ; Radiography, Thoracic ; Thoracoscopy ; Thorax ; Tomography, X-Ray Computed

BALT(bronchial associated lymphoid tissue) lymphomas are a distinct subgroup of low-grade B-cell extranodal non-Hodgkin's lymphoma, which are classified as a marginal-zone lymphomas. The majority of the patients are asymptomatic or their pulmonary lesions is often discovered incidentally on a routine chest radiograph. A 50-year-old man was admitted for an the evaluation of cough, dyspnea and fever. His chest CT showed ground glass appearance with interlobular septal thickening in both lower lobes, right middle lobe and left lingular division. He had been initially diagnosed with lipoid pneumonia and was kept under observation. However, his chest lesion showed continuous progression and a video-associated thoracoscopy was performed His pulmonary lesion was confirmed histologically to be a BALT(bronchial associated lymphoid tissue) lymphoma. We report a case of a BALT lymphoma, which was initially misdiagnosed as lipoid pneumonia.
B-Lymphocytes* ; Cough ; Dyspnea ; Fever ; Glass ; Humans ; Lymphoid Tissue* ; Lymphoma ; Lymphoma, B-Cell* ; Lymphoma, Non-Hodgkin ; Middle Aged ; Pneumonia* ; Radiography, Thoracic ; Thoracoscopy ; Thorax ; Tomography, X-Ray Computed