No abstract available.
Molecular Biology

No abstract available.
Pulmonary Artery*

No abstract available.
Humans ; Inpatients*

This study was attempted to know the recent changes of the patterns of diseases among Korean children living inurban and rural areas. 21,498 sick-children, who admitted to the thirteen general hospitals which located in urban and rural areas during past five years from Jan. 1994 to Dec. 1978, were analysed for this purpose. 13,759 sick-children(64.0%) were male, others were female and the ratio of sex was 1,8 : 1. 13,210 sick-children(61.4%)wers lived in large cities(over 500,000 population), 23.9% and 14.7$ of total sick-shildren were lived in small and medium sized cities(50,000~500,000 population) and rural areas respectively. There was a tendency to increase year by year in total number of sick children who admitted to the hospitals with the various kinds of diseases. The seasonal incidence of diseases was highest in summer, 27.9% of sick-children were admitted during summer season and the next season was fall. According to the classification of dieases in childhood (by WHO), the main diseases of sick-childen admitted at thirteen hopitals in this study were classified as respiratory tract diseases(6,044 cases, 28.1%), infection and parasitic diseases(5,605 cases, 26.1%) and neonatal disease(4,013 cases, 18.1%). Thr major ten leading causes of admission were as follows; pneumonia(13.6%), diarrheas(12.4%), prematurity(8.6%), neonatal jaundice(8.2%), URI(5.2%), bronchiolitis(3.6%), nephritis(3.3%), bacterial meningitis(3.1%), viral hepatitis(2,8%), pleurisy and empyema(2.4%). The characteristic patterns of diseases in each different resident areas were noted as follows; In large city the incidence of diseases such as intussusception, typhoid fever and hyperbilirubinemia were high comparing to other areas unexpectively. The occurrence of Japanese B encephalitis, tetanus neonatorum, poliomyelitis, septicemia, meningitis and tuberculosis were come into notice in rural areas. Diarrheal disease, prematurity, pyelonephritis and pertussis were still common in small and medium sized cities. The leading diseases in each age groups were; in neonatal period, prematurity(34.9%), hyperbilirubinemia(32.9%) and pneumonia(8.0%); in infancy, diarrheal diseases(28.2%), pneumonia(19.6%) and bronchiolitis(12.5%); in preschool period, pneumonia(16.2%), diarrheas(13.4%) and URI(6.8%); in school period, glomerulonephrithis(11.0%), pneumonia(9.7%) and viral hepatitis(8.1%); in adolescence, glomerulonephritis(11.5%), viral hepatitis(10.5%) and pneumonia(7.6%).
Child ; Adolescent ; Male ; Female ; Infant, Newborn ; Child, Preschool ; Humans ; Incidence

The purpose of the study is to minimize the incidence of glaucoma and ocular hypertension caused by using corticosteroids during induction chemotherapy for acute lymphoblastic leukemia in children. We have periodically observed the intraocular pressure and the variation of C / D ratio of two 7 years old boys with chemotherapy in our pediatric department. We observed the increase in intraocular pressure using applanation tonometer, and we managed by beta- blockers, carbonic anhydrase inhibitor and etc. Increased intraocular pressure has been normalized after chemotherapy. The frequency of occurrence of the ocular hypertension and glaucoma can be controlled with the quantity of corticosteroids used.
Adrenal Cortex Hormones ; Carbonic Anhydrases ; Child ; Drug Therapy ; Glaucoma* ; Humans ; Incidence ; Induction Chemotherapy* ; Intraocular Pressure ; Leukemia ; Ocular Hypertension ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*

PURPOSE: The aim of this study was to evaluate the food behavior and nutritional status of elementary school students in the Jeju area using Nutrition Quotient (NQ). METHODS: The subjects were 440 students (235 boys and 205 girls) in the fifth and sixth grade at four elementary schools located in Jeju. Demographic, lifestyle, and environmental information was collected using a self-reported questionnaire. The food behavior checklist for children's Nutrition Quotient (NQ), consisting of 19 items, and nutrition education related information were also obtained. RESULTS: The mean score of the children's NQ was poor, reaching 60.3 points. The percentage distribution of NQ grade was 19.8% (lowest), 18.6% (low), 45.0% (medium), 10.7% (high), and 5.9% (highest) and the factor scores for balance, diversity, abstinence, regularity, and practice were 56.6, 68.4, 71.3, 57.4, and 54.8 points, respectively. Compared with the NQ cut-off points for defining malnutrition (balance; 57, diversity; 87, abstinence; 66, regularity; 69, and practice; 67 point), average score of abstinence factor was only above the cut-off point and scores of the other factors were below the cut-off point. Subjects with higher NQ scores tended to have higher levels of exercise activity (p < 0.001), frequency of family meals (p < 0.01), and father's educational levels (p < 0.01) compared to those with lower NQ score. NQ score showed positive association with nutrition education experience and practice (p < 0.001) CONCLUSION: NQ score of elementary school students residing in Jeju was lower than the national average. More opportunities should be provided for participation in nutrition education, which incorporates a range of program strategies, as well as communication and education activities.
Checklist ; Child ; Education ; Humans ; Life Style ; Malnutrition ; Meals ; Nutritional Status*

A biloma is an extrahepatic or intrahepatic bile collection caused by traumatic, iatrogenic, or spontaneous rupture of the biliary tree. Prior reports have documented an association of a biloma with abdominal trauma and surgery, but spontaneous bile leakage associated with other primary causes has rarely been reported. A 72-year-old man was admitted to our hospital with the complaint of epigastric pain and yellowish discoloration of the sclera. Ultrasonography and computed tomography revealed a large fluid collection in the abdominal cavity. Endoscopic retrograde cholangiography demonstrated leakage of contrast medium from a distended segmental biliary branch in the left lobe of the liver. A perihepatic biloma was confirmed by sonographically guided percutaneous aspiration, and the patient underwent a left lateral segmentectomy of the liver, a cholecystectomy and T-tube choledochostomy. Histological examination showed left lateral bile duct hyperplasia, with abscess formation and chronic cholecystitis. Herein, a case of a biloma associated with choledocholithiasis is reported, with a review of the literatures.
Abdominal Cavity ; Abscess ; Aged ; Bile ; Bile Ducts ; Bile Ducts, Intrahepatic* ; Biliary Tract ; Cholangiography ; Cholecystectomy ; Cholecystitis ; Choledocholithiasis* ; Choledochostomy ; Humans ; Hyperplasia ; Liver ; Mastectomy, Segmental ; Rupture* ; Rupture, Spontaneous ; Sclera ; Ultrasonography

A 56-year-old male with a gastrointestinal stromal tumor (GIST) underwent surgical resection of the tumor. Nine months after surgery, imatinib therapy was initiated because of the discovery of metastatic tumors in the left adrenal gland and in a lymph node of the peritoneum. Seventeen months later, the patient achieved complete remission (CR) and imatinib therapy was continued. However, 48 months after initiation of imatinib therapy, computed tomography scans revealed a left adrenal gland metastasis and the patient underwent left adrenalectomy. Immunohistochemical staining indicated that the spindle-shaped cells of the resected tumor were positive for C-kit, thus confirming metastasis of the GIST. This is the first report from Korea of an adrenal gland metastasis from a GIST. Worldwide, only two such cases have been reported. Here, we describe the first case of a distant recurrence of a GIST in the left adrenal gland after CR had been achieved with the aid of surgical resection and imatinib therapy.
Adrenal Glands* ; Adrenalectomy ; Gastrointestinal Stromal Tumors* ; Humans ; Imatinib Mesylate ; Korea ; Lymph Nodes ; Male ; Middle Aged ; Neoplasm Metastasis* ; Peritoneum ; Recurrence

PURPOSE: To evaluate the characteristic CT and cerebral angiographic findings in patients with acutespontaneous subdural hematomas and correlate these imaging findings with causes of bleeding and clinical outcome. MATERIALS AND METHODS: Twenty-one patients with nontraumatic acute spontaneous subdural hematoma presentingduring the last five years underwent CT scanning and cerebral angiography was performed in twelve. To determinethe cause of bleeding, CT and angiographic findings were retrospectively analysed. Clinical history, laboratoryand operative findings, and final clinical outcome were reviewed. RESULTS: The 21 cases of acute spontaneoussubdural hematomas were caused by cerebral vascular abnormalities(n=10), infantile hemorrhagic disease(n=5), orwere of unknown origin(n=6). All ten cases of cerebral vascular abnormality were confirmed angiographically; sixwere aneurysms, three were arteriovenous malformations, and one was moyamoya disease. On CT, subarachnoidhemorrhage was seen to be associated with aneurysms, intracerebral hemorrhage with arteriovenous malformations,and intraventricular hemorrhage with moyamoya disease. All five patients with hemorrhagic disease were infantsaged 1-17 months ; characteristic diffuse distribution of subdural hematoma in both temporoparietal-occipitalregions is typical. The average overall mortality rate was 52.4%(11/21). In patients with cerebral vascularabnormalities, mortality was as low as 20%(2/10), but in hemorrhagic disease was high (60%). In cases of unknownorigin it was 100%. CONCLUSION: Acute spontaneous subdural hematoma is a rare condition, and the mortality rateis high. In patients with acute spontaneous subdural hematoma, as seen on CT, associated subarachnoid orintracerebral hemorrhage is strongly indicative of intracerebral vascular abnormalities such as aneurysm andarteriovenous malformation, and cerebral angiography is necessary. To ensure proper treatment and thus morkedlyreduce mortality, the causes of bleeding should be prompty determined by means of cerebral angiography.
Aneurysm ; Arteriovenous Malformations ; Cerebral Angiography ; Cerebral Hemorrhage ; Hematoma ; Hematoma, Subdural* ; Hemorrhage ; Humans ; Intracranial Aneurysm ; Mortality ; Moyamoya Disease ; Retrospective Studies ; Tomography, X-Ray Computed

No abstract available.
Hematocrit ; Mucocutaneous Lymph Node Syndrome*