1.Molecular analysis of childhood acute lekemia.
Hack Ki KIM ; Kyong Su LEE ; Sung Hoon CHO ; Du Bong LEE
Journal of the Korean Pediatric Society 1991;34(2):164-171
No abstract available.
Molecular Biology
2.Epidemiological Study on Diseases of Korean Children in Urban & Rural Areas.
Du Bong LEE ; Sung Hoon CHO ; Kyong Su LEE ; Byung Churl LEE
Journal of the Korean Pediatric Society 1980;23(3):173-197
This study was attempted to know the recent changes of the patterns of diseases among Korean children living inurban and rural areas. 21,498 sick-children, who admitted to the thirteen general hospitals which located in urban and rural areas during past five years from Jan. 1994 to Dec. 1978, were analysed for this purpose. 13,759 sick-children(64.0%) were male, others were female and the ratio of sex was 1,8 : 1. 13,210 sick-children(61.4%)wers lived in large cities(over 500,000 population), 23.9% and 14.7$ of total sick-shildren were lived in small and medium sized cities(50,000~500,000 population) and rural areas respectively. There was a tendency to increase year by year in total number of sick children who admitted to the hospitals with the various kinds of diseases. The seasonal incidence of diseases was highest in summer, 27.9% of sick-children were admitted during summer season and the next season was fall. According to the classification of dieases in childhood (by WHO), the main diseases of sick-childen admitted at thirteen hopitals in this study were classified as respiratory tract diseases(6,044 cases, 28.1%), infection and parasitic diseases(5,605 cases, 26.1%) and neonatal disease(4,013 cases, 18.1%). Thr major ten leading causes of admission were as follows; pneumonia(13.6%), diarrheas(12.4%), prematurity(8.6%), neonatal jaundice(8.2%), URI(5.2%), bronchiolitis(3.6%), nephritis(3.3%), bacterial meningitis(3.1%), viral hepatitis(2,8%), pleurisy and empyema(2.4%). The characteristic patterns of diseases in each different resident areas were noted as follows; In large city the incidence of diseases such as intussusception, typhoid fever and hyperbilirubinemia were high comparing to other areas unexpectively. The occurrence of Japanese B encephalitis, tetanus neonatorum, poliomyelitis, septicemia, meningitis and tuberculosis were come into notice in rural areas. Diarrheal disease, prematurity, pyelonephritis and pertussis were still common in small and medium sized cities. The leading diseases in each age groups were; in neonatal period, prematurity(34.9%), hyperbilirubinemia(32.9%) and pneumonia(8.0%); in infancy, diarrheal diseases(28.2%), pneumonia(19.6%) and bronchiolitis(12.5%); in preschool period, pneumonia(16.2%), diarrheas(13.4%) and URI(6.8%); in school period, glomerulonephrithis(11.0%), pneumonia(9.7%) and viral hepatitis(8.1%); in adolescence, glomerulonephritis(11.5%), viral hepatitis(10.5%) and pneumonia(7.6%).
Child
;
Adolescent
;
Male
;
Female
;
Infant, Newborn
;
Child, Preschool
;
Humans
;
Incidence
3.A case of unilateral absence of pulmonary artery.
Joon Ho BANG ; Sang Nyen KIM ; Jong In BYUN ; Won Bae LEE ; Byung Churl LEE ; Kyong Su LEE ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1992;35(6):873-878
No abstract available.
Pulmonary Artery*
4.Statistical Observations for Pediatric Inpatients.
Byung Cheol HAN ; Hack Ki KIM ; Byung Churl LEE ; Kyong Su LEE ; Sung Hoon CHO ; Du Bong LEE
Journal of the Korean Pediatric Society 1987;30(4):385-392
No abstract available.
Humans
;
Inpatients*
5.Radiologic Findings of Acute Spontaneous Subdural Hematomas.
Hyun Jung KIM ; Won Kyong BAE ; Jang Gyu CHA ; Gun Woo KIM ; Won Su CHO ; Il Young KIM ; Kyung Suk LEE
Journal of the Korean Radiological Society 1998;38(3):391-396
PURPOSE: To evaluate the characteristic CT and cerebral angiographic findings in patients with acutespontaneous subdural hematomas and correlate these imaging findings with causes of bleeding and clinical outcome. MATERIALS AND METHODS: Twenty-one patients with nontraumatic acute spontaneous subdural hematoma presentingduring the last five years underwent CT scanning and cerebral angiography was performed in twelve. To determinethe cause of bleeding, CT and angiographic findings were retrospectively analysed. Clinical history, laboratoryand operative findings, and final clinical outcome were reviewed. RESULTS: The 21 cases of acute spontaneoussubdural hematomas were caused by cerebral vascular abnormalities(n=10), infantile hemorrhagic disease(n=5), orwere of unknown origin(n=6). All ten cases of cerebral vascular abnormality were confirmed angiographically; sixwere aneurysms, three were arteriovenous malformations, and one was moyamoya disease. On CT, subarachnoidhemorrhage was seen to be associated with aneurysms, intracerebral hemorrhage with arteriovenous malformations,and intraventricular hemorrhage with moyamoya disease. All five patients with hemorrhagic disease were infantsaged 1-17 months ; characteristic diffuse distribution of subdural hematoma in both temporoparietal-occipitalregions is typical. The average overall mortality rate was 52.4%(11/21). In patients with cerebral vascularabnormalities, mortality was as low as 20%(2/10), but in hemorrhagic disease was high (60%). In cases of unknownorigin it was 100%. CONCLUSION: Acute spontaneous subdural hematoma is a rare condition, and the mortality rateis high. In patients with acute spontaneous subdural hematoma, as seen on CT, associated subarachnoid orintracerebral hemorrhage is strongly indicative of intracerebral vascular abnormalities such as aneurysm andarteriovenous malformation, and cerebral angiography is necessary. To ensure proper treatment and thus morkedlyreduce mortality, the causes of bleeding should be prompty determined by means of cerebral angiography.
Aneurysm
;
Arteriovenous Malformations
;
Cerebral Angiography
;
Cerebral Hemorrhage
;
Hematoma
;
Hematoma, Subdural*
;
Hemorrhage
;
Humans
;
Intracranial Aneurysm
;
Mortality
;
Moyamoya Disease
;
Retrospective Studies
;
Tomography, X-Ray Computed
6.A Case of von Gierke Disease.
Young A JOE ; Moon Young SONG ; Bin CHO ; Soon Ju LEE ; In Kyung SUNG ; Kyong Su LEE
Journal of the Korean Pediatric Society 1997;40(12):1756-1756
von Gierke disease (type Ia glycogen storage disease) is an inherited disease associated with accumulation of glycogen in the liver, kidney, intestine and erythrocytes due to the defect of glucose-6-phosphatase activity. Hepatomegaly, doll face, anemia, bleeding tendency and increased susceptability to infection are common features observed during infancy. Hypoglycemia especially fasting hypoglycemia is typical metabolic derangement in this disease, followed by metabolic acidosis, lactic acidemia, hyperlipidemia, hyperuricemia, and platelets dysfunction. We experienced a case of von Gierke disease in 6 month-old boy with doll face, hepatomegaly, fasting hypoglycemia, acidosis, anemia, hyperlipidemia, hyperuricemia, and acetonuria. Diagnosis was confirmed by light- and electron microscopic examination of liver biopsy specimen, which revealed hepatocytes filled with dense pools of glycogen and many lipid droplets. Cornstarch dietary therapy for him had favorable responses showing improvement of hypoglycemia, other metabolic derangements, and regression of hepatomegaly.
Acidosis
;
Anemia
;
Biopsy
;
Diagnosis
;
Erythrocytes
;
Glucose-6-Phosphatase
;
Glycogen
;
Glycogen Storage Disease Type I*
;
Hemorrhage
;
Hepatocytes
;
Hepatomegaly
;
Humans
;
Hyperlipidemias
;
Hyperuricemia
;
Hypoglycemia
;
Infant
;
Intestines
;
Ketosis
;
Kidney
;
Liver
;
Male
;
Starch
7.A Case of von Gierke Disease.
Young A JOE ; Moon Young SONG ; Bin CHO ; Soon Ju LEE ; In Kyung SUNG ; Kyong Su LEE
Journal of the Korean Pediatric Society 1997;40(12):1756-1756
von Gierke disease (type Ia glycogen storage disease) is an inherited disease associated with accumulation of glycogen in the liver, kidney, intestine and erythrocytes due to the defect of glucose-6-phosphatase activity. Hepatomegaly, doll face, anemia, bleeding tendency and increased susceptability to infection are common features observed during infancy. Hypoglycemia especially fasting hypoglycemia is typical metabolic derangement in this disease, followed by metabolic acidosis, lactic acidemia, hyperlipidemia, hyperuricemia, and platelets dysfunction. We experienced a case of von Gierke disease in 6 month-old boy with doll face, hepatomegaly, fasting hypoglycemia, acidosis, anemia, hyperlipidemia, hyperuricemia, and acetonuria. Diagnosis was confirmed by light- and electron microscopic examination of liver biopsy specimen, which revealed hepatocytes filled with dense pools of glycogen and many lipid droplets. Cornstarch dietary therapy for him had favorable responses showing improvement of hypoglycemia, other metabolic derangements, and regression of hepatomegaly.
Acidosis
;
Anemia
;
Biopsy
;
Diagnosis
;
Erythrocytes
;
Glucose-6-Phosphatase
;
Glycogen
;
Glycogen Storage Disease Type I*
;
Hemorrhage
;
Hepatocytes
;
Hepatomegaly
;
Humans
;
Hyperlipidemias
;
Hyperuricemia
;
Hypoglycemia
;
Infant
;
Intestines
;
Ketosis
;
Kidney
;
Liver
;
Male
;
Starch
8.A Case of Low-grade B-cell Lymphoma of Bronchial Associated Lymphoid Tissue Mimicking Lipoid Pneumonia.
Jin Hee CHO ; Min Jae YANG ; Su Kyong YU ; Kyoung Woo SOE ; Hugh Chul KIM
Tuberculosis and Respiratory Diseases 2007;63(2):194-199
BALT(bronchial associated lymphoid tissue) lymphomas are a distinct subgroup of low-grade B-cell extranodal non-Hodgkin's lymphoma, which are classified as a marginal-zone lymphomas. The majority of the patients are asymptomatic or their pulmonary lesions is often discovered incidentally on a routine chest radiograph. A 50-year-old man was admitted for an the evaluation of cough, dyspnea and fever. His chest CT showed ground glass appearance with interlobular septal thickening in both lower lobes, right middle lobe and left lingular division. He had been initially diagnosed with lipoid pneumonia and was kept under observation. However, his chest lesion showed continuous progression and a video-associated thoracoscopy was performed His pulmonary lesion was confirmed histologically to be a BALT(bronchial associated lymphoid tissue) lymphoma. We report a case of a BALT lymphoma, which was initially misdiagnosed as lipoid pneumonia.
B-Lymphocytes*
;
Cough
;
Dyspnea
;
Fever
;
Glass
;
Humans
;
Lymphoid Tissue*
;
Lymphoma
;
Lymphoma, B-Cell*
;
Lymphoma, Non-Hodgkin
;
Middle Aged
;
Pneumonia*
;
Radiography, Thoracic
;
Thoracoscopy
;
Thorax
;
Tomography, X-Ray Computed
9.A Case of Low-grade B-cell Lymphoma of Bronchial Associated Lymphoid Tissue Mimicking Lipoid Pneumonia.
Jin Hee CHO ; Min Jae YANG ; Su Kyong YU ; Kyoung Woo SOE ; Hugh Chul KIM
Tuberculosis and Respiratory Diseases 2007;63(2):194-199
BALT(bronchial associated lymphoid tissue) lymphomas are a distinct subgroup of low-grade B-cell extranodal non-Hodgkin's lymphoma, which are classified as a marginal-zone lymphomas. The majority of the patients are asymptomatic or their pulmonary lesions is often discovered incidentally on a routine chest radiograph. A 50-year-old man was admitted for an the evaluation of cough, dyspnea and fever. His chest CT showed ground glass appearance with interlobular septal thickening in both lower lobes, right middle lobe and left lingular division. He had been initially diagnosed with lipoid pneumonia and was kept under observation. However, his chest lesion showed continuous progression and a video-associated thoracoscopy was performed His pulmonary lesion was confirmed histologically to be a BALT(bronchial associated lymphoid tissue) lymphoma. We report a case of a BALT lymphoma, which was initially misdiagnosed as lipoid pneumonia.
B-Lymphocytes*
;
Cough
;
Dyspnea
;
Fever
;
Glass
;
Humans
;
Lymphoid Tissue*
;
Lymphoma
;
Lymphoma, B-Cell*
;
Lymphoma, Non-Hodgkin
;
Middle Aged
;
Pneumonia*
;
Radiography, Thoracic
;
Thoracoscopy
;
Thorax
;
Tomography, X-Ray Computed
10.Adrenal Gland Metastasis of a Gastrointestinal Stromal Tumor.
Hyeon Jeong KANG ; Hye Jin CHO ; Kyung Hyun KIM ; Mi Kyong JOUNG ; Jae Uk SHIN ; Su Sin JIN
Korean Journal of Medicine 2017;92(5):471-475
A 56-year-old male with a gastrointestinal stromal tumor (GIST) underwent surgical resection of the tumor. Nine months after surgery, imatinib therapy was initiated because of the discovery of metastatic tumors in the left adrenal gland and in a lymph node of the peritoneum. Seventeen months later, the patient achieved complete remission (CR) and imatinib therapy was continued. However, 48 months after initiation of imatinib therapy, computed tomography scans revealed a left adrenal gland metastasis and the patient underwent left adrenalectomy. Immunohistochemical staining indicated that the spindle-shaped cells of the resected tumor were positive for C-kit, thus confirming metastasis of the GIST. This is the first report from Korea of an adrenal gland metastasis from a GIST. Worldwide, only two such cases have been reported. Here, we describe the first case of a distant recurrence of a GIST in the left adrenal gland after CR had been achieved with the aid of surgical resection and imatinib therapy.
Adrenal Glands*
;
Adrenalectomy
;
Gastrointestinal Stromal Tumors*
;
Humans
;
Imatinib Mesylate
;
Korea
;
Lymph Nodes
;
Male
;
Middle Aged
;
Neoplasm Metastasis*
;
Peritoneum
;
Recurrence