1.Two cases of Hemolytic Uremic Syndrome Associated with Escherichia coli O114.
Su Jeun RYU ; Hyewon HAHN ; Soo Jin YOO ; Byung Sun LEE ; Jae Kyoo LEE ; Mi Na KIM ; Eui Chong KIM ; Young Seo PARK
Journal of the Korean Society of Pediatric Nephrology 2002;6(1):102-108
We report two cases of hemolytic uremic syndrome (HUS) associated with Escherichia coli O114. Two cases were similar and showed the same clinical courses. After prodrome of diarrhea and vomiting lasting 1-2 days, azotemia persisted for about 10 days, and during that period, the patients were on peritoneal dialysis. They recovered without any sequelae after about 15 days. Direct multiplex PCR of stool culture revealed eae and stx2 gene and the result of ELISA done on the colony positive of eae gene confirmed Escherichia coli O114. This is the first report of HUS associated with Escherichia coli O114. We recommend, Shiga toxin producing bacterial infection must be considered and efforts should be made to scrutinize the organism in all diarrhea-prodrome HUS patients.
Azotemia
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Bacterial Infections
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Diarrhea
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Enzyme-Linked Immunosorbent Assay
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Escherichia coli*
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Escherichia*
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Hemolytic-Uremic Syndrome*
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Humans
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Multiplex Polymerase Chain Reaction
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Peritoneal Dialysis
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Shiga Toxin
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Vomiting