1.IL-12 and TNF-alpha productions from human peripheral blood mononuclear cells in untreated patients with active pulmonary tuberculosis stimulated with 30-kDa or TSP antigen of Mycobacterium tuberculosis H37Rv.
Chang Hwa SONG ; Eun Kyeong JO ; Dae Su KIM ; Hwa Jung KIM ; Jae Hyun LIM ; Un Ok KIM ; Tae Hyun PAIK ; Jeong Kyu PARK
Immune Network 2001;1(3):250-259
No abstract available.
Humans*
;
Interleukin-12*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Tuberculosis, Pulmonary*
;
Tumor Necrosis Factor-alpha*
2.The Effect of Antioxidant Vitamins Supplementation on Blood Pressure, Plasma Lipids, Folate, and Homocysteine Levels in Smokers and Non-Smokers of College Students in the Gyeonggi Area.
Su Ra KIM ; Hye Sun MIN ; Ae Wha HA ; Hwa Jin HYUN ; Kyung Hee SONG
Korean Journal of Community Nutrition 2004;9(4):472-482
This study was performed to investigate the effect of vitamin C and E supplementation on blood pressure, plasma lipids, folate, and homocysteine levels in smokers and non-smokersof college male students in Gyeonggi Area. The nutrient intakes were determined by a 24hr-recall method. The subjects were divided into six groups: vitamin C supplementation group (n: smokers = 10, nonsmokers = 10), vitamin E supplementation group (n: smokers = 10, nonsmokers = 10), vitamin C and E supplementation group (n: smokers = 10, nonsmokers = 10), respectively. There were no significant differences between the smokers and nonsmokers in terms of anthropometric measurements. Systolic and diastolic blood pressure were significantly higher (p < 0.05) in smokers than that of non-smokers. There was no significant difference in energy and other nutrients intakes between smokers and non-smokers. In plasma lipids levels, smokers had higher plasma triglyceride, LDL-cholesterol, VLDL-cholesterol, total cholesterol concentration than that of non-smokers (p < 0.05). HDL-cholesterol level of smokers had a tendency to be lower than that of nonsmokers. In smokers, AI, TPH, LPH were significantly higher than that of non-smokers (p < 0.01). Plasma folate, homocysteine levels were not significantly different between smokers and non-smokers. The effect of antioxidant vitamins supplementation in smokers: In vitamin C supplementation group, HDL-cholesterol level was significantly increased (p < 0.01) and AI, TPH, LPH were significantly decreased (p < 0.01). In vitamin E supplementation group, HDL-cholesterol level was significantly increased (p < 0.05). In vitamin C and E supplementation group, LPH was significantly decreased (p < 0.05). The effect of antioxidant vitamins supplementation in non-smokers: HDL-cholesterol level was significantly increased (p < 0.05) and AI, TPH, LPH were significantly decreased (p < 0.05) by vitamin C supplementation group. Plasma homocysteine level was decreased by vitamin E supplementation group in non-smokers p < 0.01). The results of this study showed that smoking had a tendency to increase plasma lipids levels that factor into the risk of coronary heart disease. It is considered that antioxidant vitamin supplementation in smokers had a tendency to decrease cardiovascular disease than in nonsmokers.
Ascorbic Acid
;
Blood Pressure*
;
Cardiovascular Diseases
;
Cholesterol
;
Coronary Disease
;
Folic Acid*
;
Gyeonggi-do*
;
Homocysteine*
;
Humans
;
Male
;
Plasma*
;
Smoke
;
Smoking
;
Triglycerides
;
Vitamin E
;
Vitamins*
3.Comparison of Concurrent Chemoradiotherapy with Conventional Radiotherapy in Advanced Non-smal Cell Lung Cancer.
Hui Jung KIM ; Dong Soo LEE ; So Hyang SONG ; Su Mi JUNG ; Young Kyoon KIM ; Se Chul YOON ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1997;44(3):493-504
BACKGROUND: Non-small cell lung cancer is one of the most frequent cause of death due to cancer in men, and its incidence among women is rapidly increasing. Although there has been a recent surge of interest in combined modality therapy for stage III non-small cell lung cancer(NSCLC), the optimal treatment is still not well established. Thoracic irradiation has long been the gold standard for locally advanced unresectable NSCLC. However, although conventional radiotherapy(XRT) can palliate symptom and improve local control of disease, it huts at most only a modest effect on survival. Recently, cisplatin(cia-diamminedichloroplatinum ) has been reported to enhance the cell-killing effect of radiation For patients with unresectable NSCLC, cisplatin-based concurrent chemoradiotherapy(CCRT) had the advantage of therapeutic response over XRT alone and therapeutic side effect more commonly occurred in CCRT group in EORTC(European Organization for Research and Treatment of Cancer) and other trials. Objectives : We compared therapeutic response, compliance, and side effects between CCRT and XRT in patients with advanced NSCLC. Patients and METHOD: Thirty patients with biopsy-proven inoperable NSCLC were randomized to one of two treatment arms. Arm A consisted of XRT, radiotherapy for 4~6 weeks(1.8 Gy given 20~33 times, in five fractions a week), and arm B consisted of CCRT, radiotherapy for 2 weeks(3 Gy given 10 times, in five fractions a week), followed by 3 week rest period and then radiotherapy 2 more weeks(2.5 Gy given 10 timed in five fractions a week), combined with 6mg cisplatin per square meter, given daily before radiotherapy. We evaluate therapeutic response, compliance, change of performance status, side effects, and radiation pneumonitis by using the author's made scoring system. RESULTS: There was no significant difference in therapeutic response and compliance. But there was a significantly lower laboratory complication and radiation pneumonitis in CCRT group (p<0.05). There's significant negative correlation between stage and therapeutic response score in both groups(R=0.353, p<0.05). In both groups, patients with squamous cell carcinoma had a tendency to higher therapeutic response score than those with adenocarcinoma. CONCLUSION: There was. no difference between CCRT and XRT in respect to therapeutic response and compliance. But CCRT had a advantage of decreased side effects.
Adenocarcinoma
;
Arm
;
Carcinoma, Non-Small-Cell Lung
;
Carcinoma, Squamous Cell
;
Cause of Death
;
Chemoradiotherapy*
;
Cisplatin
;
Combined Modality Therapy
;
Compliance
;
Female
;
Humans
;
Incidence
;
Lung Neoplasms*
;
Lung*
;
Male
;
Radiation Pneumonitis
;
Radiotherapy*
4.A Case of Complex Cardiac Myxoma Combined with Nipple Myxoma.
Gwang Gook KIM ; Heung Sun KANG ; Gye Won LEE ; Min Su SONG ; Jin Man CHO ; Jung Hwi CHO ; Jung Sang SONG ; Jong Hwa BAE
Korean Circulation Journal 1998;28(3):453-457
The majority of cardiac myxoma occur sporadically as isolated lesions in the left atrium of middle-aged women. However, a familial form and a syndrome form of this lesion have also been identified. The syndrome myxoma can present itself with pigmented skin lesions and peripheral or endocrine neoplasms. The familial and syndrome forms of cardiac myxomas can usually be distinguished from the sporadic form by their occurrences at younger ages, their unusual locations, the multicentricity of the lesions, and the presence of rare pathological conditions. In addition, a higher rate of recurrent lesions is usually associated with the familial and syndrome forms of this disease. We present a case of complex cardiac myxoma with pigmented skin lesions and breast myxoma and report it with a review of literature.
Breast
;
Female
;
Heart Atria
;
Humans
;
Myxoma*
;
Nipples*
;
Skin
5.Acromicric Dysplasia Caused by a Novel Heterozygous Mutation of FBN1 and Effects of Growth Hormone Treatment.
Hyung Suk JIN ; Ho young SONG ; Sung Yoon CHO ; Chang Seok KI ; Song Hyun YANG ; Ok Hwa KIM ; Su Jin KIM
Annals of Laboratory Medicine 2017;37(1):92-94
No abstract available.
Bone Diseases, Developmental/diagnosis/drug therapy/*genetics
;
Child
;
Fibrillin-1/*genetics
;
Hand/diagnostic imaging
;
Heterozygote
;
Human Growth Hormone/therapeutic use
;
Humans
;
Limb Deformities, Congenital/diagnosis/drug therapy/*genetics
;
Male
;
Pelvis/diagnostic imaging
6.A Case of Endobronchial Mass-Like Rasmussen Aneurysm.
Jeong Rok LEE ; Su Hwa LEE ; Sung Hoon JUNG ; So Hyang SONG ; Chi Hong KIM ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 2004;56(1):85-90
A 69 year-old female was admitted to the hospital due to intermittent hemoptysis for 1 month. Emergent bronchoscopy revealed mass-like lesion almost completely obstructing right intermediate bronchus with multiple hemorrhagic spots. Bronchial arterial angiography was performed but failed to find out actively bleeding vessel. Spiral computerized tomography of the chest showed contrast enhanced bulging of the posterior portion of right main bronchus into the lumen of right intermediate bronchus suggesting Rasmussen aneurysm. The AFB smear of bronchial washing fluid was positive. Pulmonary arterial angiography and embolization were not performed due to improvement of clinical course with medical conservative care. Here we report a case of endobronchial mass-like Rasmussen aneurysm grossly suspected by bronchoscopy and diagnosed by spiral CT, which successfully managed by medical conservative care with antituberculous agents.
Aged
;
Aneurysm*
;
Angiography
;
Bronchi
;
Bronchoscopy
;
Female
;
Hemoptysis
;
Hemorrhage
;
Humans
;
Thorax
;
Tomography, Spiral Computed
7.Five-Year Outcomes of the IRIS Procedure for the Treatment of Female Stress Urinary Incontinence: Comparison with the TVT Procedure.
Phil Hyun SONG ; Chang Ho HYUN ; Hwa Su LIM ; Hee Chang JUNG
Korean Journal of Urology 2009;50(8):767-773
PURPOSE: We evaluated the long-term efficacy and safety of the innovative replacement of incontinence surgery (IRIS) procedure and compared these with the tension-free vaginal tape (TVT) procedure for the treatment of female stress urinary incontinence. MATERIALS AND METHODS: We included 111 consecutively treated women who underwent IRIS (n=51) or TVT (n=60) between January 2002 and December 2003 and followed them up for at least 5 years postoperatively. We analyzed the 5-year success rate and postoperative complications of the IRIS procedure and compared these with the results of the TVT procedure. RESULTS: The 5-year success rate was 92.2% for the IRIS procedure and 93.3% for the TVT procedure, and the satisfaction rates were 90.2% and 85.0%, respectively. Intraoperative complications for the IRIS group included 4 cases of bladder perforation, and there were 5 cases of bladder perforation in the TVT group. The postoperative complications for the IRIS group included 3 patients with de novo urgency, 2 patients with mesh exposure, and 1 patient with temporary urinary retention. Four patients in the TVT group developed de novo urgency, 2 patients had mesh exposure, and 2 patients showed temporary urinary retention. CONCLUSIONS: Our results suggest that IRIS may be an effective and safe procedure compared with the TVT procedure for more than 5 years.
Female
;
Humans
;
Intraoperative Complications
;
Iris
;
Postoperative Complications
;
Suburethral Slings
;
Urinary Bladder
;
Urinary Incontinence
;
Urinary Retention
;
Urologic Surgical Procedures
8.Factors Affecting Performance of Hand Hygiene by Parents of Hospitalized Infants.
Su Jin JIN ; Young Mi SONG ; Hye Young HAN ; Kyung Hwa SEO ; Soon Jeong KIM
Child Health Nursing Research 2015;21(4):285-292
PURPOSE: Purpose of this study was to identify factors affecting the performance of hand hygiene by parents of hospitalized infants. METHODS: The study was conducted with 209 parents of hospitalized infants from one hospital in Changwon. Data were collected from June through August, 2014 and analyzed using SPSS Win 18.0 program. RESULTS: There were positive correlations between performance of hand hygiene and perceptions of sanitary formula bottle (r=.586, p<.001), attitude to hand hygiene (r=.438, p<.001), and knowledge of hand hygiene (r=.405, p<.001) and between parent efficacy and perceptions of sanitary formula bottle (r=.572, p<.001). Awareness of perceptions of sanitary formula bottle (beta=.308, p<.001), parent efficacy (beta=.281, p<.001) and hand hygiene attitude (beta=.207, p<.001) were significant predictors of hand hygiene performance and explained 46.1% of the variance. CONCLUSION: To increase infection control medical institutions should provide education on hand hygiene and training for parents of hospitalized infants. In order to enhance the performance of hand hygiene, it is necessary to develop and apply nursing programs for hospitalized infants that include hand hygiene attitude, maintenance of the sanitary formula bottle and parent efficacy.
Bottle Feeding
;
Education
;
Gyeongsangnam-do
;
Hand Hygiene*
;
Hand*
;
Humans
;
Infant*
;
Infection Control
;
Nursing
;
Parents*
9.A Case of Neonatal Atrial Flutter Treated by Propafenone after Fetal Echocardiographic Diagnosis.
Kyung Hwa LEE ; Chang Woo HA ; Chul Ho KIM ; Min Seob SONG ; Moon Su SUNG
Journal of the Korean Pediatric Society 2002;45(7):928-932
Perinatal atrial flutter is a potentially lethal arrhythmia. Management of this disorder is difficult and controversial. Fetal atrial flutter is a serious and life threatening rhythm disorder particulary when it causes hydrops; it may be associated with fetal death or neurological damage. Although the initial episode of flutter may be difficult to control, recurrence of atrial flutter after successful resolution of the arrhythmia seems highly unlikely and long-term prognosis is excellent. We experienced a case of a atrial flutter diagnosed in utero at 38+6 weeks' gestation by fetal cardiac echocardiography. He was treated with maternal digoxin, but he continued to have atrial flutter until delivery. Restoration of sinus rhythm occured with propafenone therapy in this patient after failure of initial digoxin therapy and direct current cardioversion.
Arrhythmias, Cardiac
;
Atrial Flutter*
;
Diagnosis*
;
Digoxin
;
Echocardiography*
;
Edema
;
Electric Countershock
;
Fetal Death
;
Humans
;
Pregnancy
;
Prognosis
;
Propafenone*
;
Recurrence
10.Balloon dilatation for the treatment of stricture of gastrojejunostomy.
Yeon Hwa CHOI ; Ho Young SONG ; Young Min HAN ; Su Bin CHON ; Gyung Ho CHUNG ; Chong Soo KIM ; Ki Chul CHOI
Journal of the Korean Radiological Society 1993;29(4):742-746
Enteroenteric anastomotic strictures of UGI tract are common and require treatment if significant obstruction occurs. We performed fluoroscopic guided balloon dilatation in 6 patients who had symptomatic stricture of gastrojejunostomy. The stricture was successfully resolved in 4 patients with benign stricture. But 2 patients with malignant stricture had recurrence of obstructive symptom 2 weeks later, and they required a stent. Asymptomatic balloon rupture was seen in one patient, but other procedural complications did not occur. We found that fluoroscopic guided balloon dilatation is an effective and safe method in the treatment of anastomotic stricture of gastrojejunostomy. We also found transient effect in malignant gastrojejunal anastomotic strictures, which required an interventional procedure, such as placement of a stent.
Constriction, Pathologic*
;
Dilatation*
;
Gastric Bypass*
;
Humans
;
Methods
;
Recurrence
;
Rupture
;
Stents