1.A Meridian Visualization System Based on Impedance and Binocular Vision.
Chinese Journal of Medical Instrumentation 2015;39(3):166-169
To ensure the meridian can be measured and displayed correctly on the human body surface, a visualization method based on impedance and binocular vision is proposed. First of all, using alternating constant current source to inject current signal into the human skin surface, then according to the low impedance characteristics of meridian, the multi-channel detecting instrument detects voltage of each pair of electrodes, thereby obtaining the channel of the meridian location, through the serial port communication, data is transmitted to the host computer. Secondly, intrinsic and extrinsic parameters of cameras are obtained by Zhang's camera calibration method, and 3D information of meridian location is got by corner selection and matching of the optical target, and then transform coordinate of 3D information according to the binocular vision principle. Finally, using curve fitting and image fusion technology realizes the meridian visualization. The test results show that the system can realize real-time detection and accurate display of meridian.
Calibration
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Electric Impedance
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Electrodes
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Humans
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Meridians
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Vision, Binocular
2.Thickness distribution of adolescent palatal bone studied by CBCT
Journal of Practical Stomatology 2014;(6):783-786
Objective:To study the thickness distribution palatal bone in adolescents and provide a clinical reference for implanting mini-screws.Methods:Cone-beam CT head scan data of palate of 20 adolescent orthodontic patients were measured with NNT Viewer software.60 points of the palate bone on one side were designed as 1 -10 in sagittal direction and as A -F in transvers direction with incisive foramen as the point of A and 0,the distance between each 2 adjacent points was 2 mm.The bone thickness of the 60 points were measured and statistically analyzed.Results:There were no significant differences among B2,B3,C2,C3,D3,E3,E4,F4 and F5(P >0.05).Statistically significant difference was found between F3 and B2 or B3,C2,C3,D3,E3,E4,F4 and F5(P <0.05).There was significant difference between D3 and D4(P <0.05).Conclusion:The appropriate areas for implanting mini-screws in palate may be about 2 -4 mm near the palatal suture and 4 -6 mm behind incisor canal,and 8 -10 mm near the palatal su-ture,6 -8 mm behind incisor canal.Those regions are safe for implanting mini-screws and can provide about 6 mm bone tissue sup-port.
3.Study on clinical practice teaching of foreign students in respi ratory medicine
Chinese Journal of Medical Education Research 2003;0(04):-
Some problems have influence on the quality of Clinical practice teaching of foreign students,including language communication barriers,teacher shortage and so on.To solve these problems,we worked hard on the rationale use of teachers,improvement of the teacher’s English level,giving lecture and collecting opinions to improve the quality of teaching.
4.Platelet activating factor in the pathogenesis of SMAO shock and therapeutic effect of anisodamine
Chinese Journal of Pathophysiology 1989;0(06):-
The changes of PAF activity and the effects of anisodamine (654-2) were studied in the superior mesenteric artery occlusion (SMAO)shock in rabbits. The results showed that plasma PAF activity increased from 3.88?0.82 AU/ml before SM-AO to 9.71?1.26 AU/ml (P
6.Research progress of zebrafish used in drug metabolism.
Acta Pharmaceutica Sinica 2011;46(9):1026-31
Zebrafish is widely used as a model organism in the process of drug discovery. It expresses drug metabolizing enzymes like cytochrome P450 (CYP450), uridine 5'-diphospho-glucuronosyltransferase (UGT) and nuclear receptors like pregnane X receptor (PXR), aryl hydrocarbon receptor (AHR), etc. This article summarized the profiles of main drug metabolizing enzymes and nuclear receptors, and reviewed the advances on xenobiotics metabolism in zebrafish.
7.THE ORIGIN OF NORADRENERGIC FIBERS IN THE SEPTUM OF THE RAT——A STUDY OF COMBINED RETROGRADE FLUORESCENT LABELING AND HISTOFLUORESCENCE
Acta Anatomica Sinica 1957;0(04):-
21 albino rats were used. The origin of the noradrenergic (NA) fibers in the septum was studied with a simultaneously combined retrograde fluorescent tracing and histofluorescence method. The results revealed that the NA neurons projecting to the septum were in A_1, A_2 and A_6 groups. The projections of A_1 were bilateral, But A_2 and A_6 projected dominantly to the ipsilateral septum, with a few to the contralateral. Retrograde labeled NA cells were localized in the rostrodorsal part of A_6 group, and scattered over the whole rostrocaudal length of A_(1,2) groups. No labeling was seen in A_4 and A_7 groups. In five of the animals, retrograde labeled NA cells were occasionally observed in A_5 group. In addition, some scattered labeled non-NA neurons were seen in the raphe and the ventrolateral reticular formation of the rostral medulla.
8.The Effect of Combined Radiation-Burn Injury on Intestinal Epithelium in Mice
Journal of Third Military Medical University 1983;0(04):-
Seven hundred and forty-six mice, weighing 30-35 grams, were divided into four groups randomly. The animals of the first three groups were inflicted with radiation injury (12 Gy total body irradiation from a Co60 source) , burn injury (15% of third degree burns), and combined injury of radiation and burns(12 Gy total body irradiation and 15% of third degree burns) respectively. The fourth group worked as normal control.The mortality and the dynamic changes of the intestinal epithelium of the experimental animals were studied. It was found that the clinical course of the combined injury group was quite different from other two. The mortality of the combined injury group was higher and the damage on the intestinal epithelium was more severe than those of the radiation injury group in the first 48 hours after injury. In the second 48 hours, the mortality of the combined injury group became lower and the recovery of the intestinal epithelium faster.The reactions of the experimental animals to the combined injury of radiation and burn were-very complicate. Further investigation is essential to elucidate the mechanism and to formulate appropriate therapeutic measures.
9.INTRACEPHALIC DIFFUSION AND SELECTIVE LABELING OF PROPIDIUM IODIDE INJECTED INTO THE LATERAL CEREBRAL VENTRICLE
Sheng CHEN ; Hongsen SU ;
Acta Anatomica Sinica 1953;0(01):-
Injections of propidium iedide (PI) into the lateral cerebral ventricle (LV) ofthe rat resulted in a prominent abnormality characterized by tremor,ataxia,andnystagmus.The intensity of PI fluorescence in the parenchyma of the brain fadedgradually away from the injection site and ventricles to the surfaces of the brain. In the forebrain it was seen that PI fluorescence reached the most lateral part ofthe ipsilateral caudate putamen nucleus.A constant neuronal labeling was observedin the septohippocampal nuclei,the A8-9-10 dopaminergic cell groups of themidbrain,the dorsal raphe nucleus,the median raphe nucleus,neurons within anddorsal to the medial lemniscus of the caudal midbrain,and Furkinje cells of thecerebellum.This neuronal labeling was bilateral.No distinct labeling was seen inother areas of the brain.Combined with Faglu histofluorescence,it was found thatalmost all of the dopaminergic neurons in the midbrain exhibited PI fluorescence.No labeled non-dopaminergic neuron was seen in A8-9-10.With a transection ofthe unilateral medial forebrain bundle,a prominent accumulation of PI fluorescencewas seen within the distal segments of catecholaminergic fibers near the transection,but no accumulation of PI was seen in the proximal segments.With LV injectionof Evans blue(EB)or DAPI or ethidium bromide,animals did not exhibit anyvisible abnormality.In animals with LV injection of EB or DAPI,although somelabeled cells were seen in the distant areas of the brain,their distribution wasdistinctly different from that of PI labeling.The above results indicate that besidesconfirming the LV injection of PI results in a prominent abnormality and PI isselectively uptaken by Purkinje cells,we have found that:a)PI is able to enter theparenchyma from the cerebrospinal fluid and diffuse widely in the brain;b)LVinjection of PI results in a selective labeling in certain specific areas of the brain,and those selectively labeled cells in A8-9-10 all are dopaminergic neurons;c)these dopaminergi(?) cells are labeled through axonal uptake and retrograde transportof PI.
10.Study on Extraction Technology of Fat-Soluble Effective Componets of Radix Salviae Miltiorrhizae by SFE-CO_2
Ziren SU ; Jiannan CHEN ;
Chinese Traditional Patent Medicine 1992;0(08):-
The tanshinone ⅡA,an effective component of Radix Salviae Miltiorrhizae(RSM)can be extracted up to 90% in alcohol,but mostly decomposed in the later concentrating and drying procedures.Although reducing-pressure concentrating processes can reduce the decomposi- tion in experiment,but it can not preserve effectively the tanshinone during the large scale production because of the extended time of tanshinone in dampness and heat.Supercritical carbon dioxide extraction(SFE-CO_2)of RSM can give crystalline substance and dark red modifier when the alcohol is used as modifier at extraction pressure of 10 Mpa and the tem- perature at 40℃.The SFE-CO_2 technology can get higher concentration of tanshinone and be used during preparation production directly.The SFE-CO_2 technology is superior to the alco- hol-extraction technology.