Humans ; Stress, Mechanical ; Thrombosis ; etiology

OBJECTIVETo investigate the effects of time varied stress on the shape-alteration of myoblast in rats and to provide a theoretic base to determine the mechanics of myoblast in orthodontic therapy.

METHODSBased on the pulsatile mechanical system our group founded, this study loaded different strain (2.5 kPa, 5.0 kPa and 10.0 kPa) to the myoblast of lateral pterygoid muscle. The alterations in shape under time varied stress of 6 h and 12 h were assessed by phase-contrast microscopy, scanning electron microscope.

RESULTSThe orientation of myoblast seemed no obvious orderliness before loading. But after loading the lower time varied strain (2.5 kPa, 5.0 kPa), they were changed their orientation to paralel with the direction of strain along with the membrane. Meanwhile, there had one trend to set the shape of myoblast more upright along with the membrane after loading the higher time varied stress (10.0 kPa).

CONCLUSIONIt was proved that the different time varied stress in vitro expressed the different influence on the remolding of myoblast.

experimental test for mechanical properties of a vascular stent is a main method to evaluate its effectiveness and safety, which is of great significance to the clinical applications. In this study, a comparative study of planar, V-groove and radial compression methods for the radial support property test were performed, and the effects of compression rate and circumferential position on the test results were conducted. Based on the three-point bending method, the influences of compression rate and circumferential position on flexibility were also explored. And then a best test proposal was selected to evaluate the radial support property and flexibility of the three self-designed stents and the comparative biodegradable vascular stent (BVS) (BVS1.1, Abbott Vascular, USA) with different outside diameters of 1.4 mm, 1.7 mm and 2.4 mm. The results show that the developing trends of the compression load with the compression displacement measured by the three radial support property test methods are the same, but normalized radial force values are quite different. The planar compression method is more suitable for comparing the radial support properties of stents with different diameters and structures. Compression rate has no obvious effect on the testing results of both the radial support property and flexibility. Compression circumferential position has a great impact on testing radial support property with the planar or V-groove compression methods and testing flexibility with three-point bending method. The radial support properties of all the three self-designed stents are improved at a certain degree compared to that of the BVS stent. The study has better guide significance and reference value for testing mechanical properties of vascular stents.
Absorbable Implants ; Mechanical Phenomena ; Polymers ; Prosthesis Design ; Stents ; Stress, Mechanical

PURPOSE: The purpose of this study was to evaluate the success rate of dental implant on post-traumatic region to rehabilitate missing teeth. PATIENTS AND METHODS: 5 patients who had been treated due to maxillofacial trauma during 2000 to 2004 at samsung medical center were selected for this study. 22 dental implants were installed to them for restoring missing teeth. The success rate of these dental implants was evaluated with criteria by T. Albrektsson .We divided installed 22 implants into 2 categories. One category consisted rough surface implants group and smooth surface implants group. And the other category consisted more healing group and less healing group. The healing time was calculated from point of trauma. RESULTS: The success rate of dental implants is 68.2% that is lower than other studies because of poor vascularity of bone bed and mechanical stress according to trauma. Rough surface implants group and More healing group showed superior success rate to others. (P < 0.05) CONCLUSION: We found that to increase success rate, it may need rough surface implants and longer healing period.
Dental Implants* ; Humans ; Prognosis* ; Stress, Mechanical ; Tooth

Stent fracture is likely to be caused due to mechanical stress at the hinge point or kinking movement at the point of aneurysm formation with stent malapposition. To our knowledge, this is the first published report of stent fracture at the proximal shaft of the left main stem in a patient with acute myocardial infarction.
Aneurysm ; Humans ; Myocardial Infarction ; Stents ; Stress, Mechanical

No abstract available.
Cell Cycle* ; Humans* ; Periodontal Ligament* ; Stress, Mechanical*

In this study, a 3D model of a transtibial monolimb and residual limb was constructed. The stresses on all nodes of the model under the simulus of the load at the Mid-Stance were computed through 3D finite element analysis (FEA). The stress distribution on the internal and external surfaces of the model was obtained. The results indicate that the stresses on socket are lower than those on prosthetic shank; high stress regions are located on the underneath of prosthetic shank and the border section of socket and prosthetic shank. These data will be useful for CAD\CAM system of monolimb designing.
Artificial Limbs ; Finite Element Analysis ; Stress, Mechanical

OBJECTIVETo investigate morphological change of osteoblasts cultured on titanium plates with different microarchitecture structure when exposured to fluid shear stress.

METHODS14 dynes x cm(-2) fluid shear stress was applied on osteoblasts cultured on 3 different commercially pure titanium plates: Polished treatment (PT), sandblast (SB), sandblasting and acid-base (SB-AB) surfaces. Scanning electron microscope (SEM) was adopted to observe the morphological changes after 0.5, 4, 7.5 h time point respectively.

RESULTSMorphologically, no significant changes were observed after 0.5 h and few osteoblasts were seen after 7.5 h on all 3 type of different surfaces, and significant changes could only be observed after 4 h. Osteoblasts were elongated and rearranged along the flow way on different levels on PT surface. Shape of cells was altered, from long fusiform suspending over depressed areas into polygon stretching out many synapsises tightly attached to pits on SB-AB surface. Osteoblasts on SB surface displayed similar change as SB-AB surface, besides, some cells were elongated along the way of flow, stretching out threadlike synapsises attached to edges of pits.

CONCLUSIONMorphological change of osteoblast responding to fluid shear stress in physiological range depends on substrate microarchitecture and varies with the time of fluid shear stress application.

OBJECTIVETo photoelastically investigate the difference in load distribution of Tension More (TM) implants with different conical angle designs.

METHODSThe following five groups of implants of different conical angles were designed: cylinder implant, upper 1/3 TM implant (taper length of 3 mm); 1/2 TM implant (taper length of 5 mm); lower 1/3 TM implant (taper length of 7 mm); and bottom TM implant (taper length of 10 mm). The implants were centrally located in individually photoelastic models consisting of a simulated trabecular bone and a 1 mm-thick layer of cortical bone. Vertical and 45° oblique static loads were applied at the center of the superstructures. The resulting stresses were monitored photoelastically and recorded photographically. RESULTS With vertical loading, the cylinder implant showed higher stress levels in the cortical bone and trabecular bone than the upper 1/3 TM implant, 1/2 TM implant, and lower 1/3 TM implant. The four groups of TM implants showed lower stress levels in the cortical bone than the cylinder implant under oblique loads. The least favorable stress concentration in cortical bone was observed in the upper 1/3 TM implant under vertical and oblique loads.

CONCLUSIONTM implants of rational conical angle designs seem to be effective in stress distribution. For all designs and load directions, the upper 1/3 TM implant is the most favorable around the crest.

As a kind of mechanical effector cells, chondrocytes can produce a variety of physical and chemical signals under the stimulation of multiaxial load
Apoptosis ; Cells, Cultured ; Chondrocytes ; Stress, Mechanical