1.An Alternative Approach to Tuberculosis Management with Intravenous Streptomycin.
Sang Young KIM ; H Christian HONG ; Jong Hun KIM ; Ji Won RYU ; Han Seop CHOI ; Yeon Tae CHUNG ; Joon Sung JOH
Infection and Chemotherapy 2010;42(1):39-42
Streptomycin is currently utilized to treat advanced tuberculosis in Korea. However, the usefulness of intravascular streptomycin is not fully understood. In this study, streptomycin was administered intravenously in 30 patients. Intravenous administration of streptomycin may be a useful route of administration without undesirable toxicities.
Administration, Intravenous
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Humans
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Korea
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Mycobacterium tuberculosis
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Streptomycin
;
Tuberculosis
2.Comparative Vestibulotoxicity of Different Aminoglycosides in the Guinea Pigs.
Erol SELIMOGLU ; Saadettin KALKANDELEN ; Fazli ERDOGAN
Yonsei Medical Journal 2003;44(3):517-522
The histopathological alterations in the vestibule due to aminoglycosides are well defined. Although there are reports comparing the vestibulotoxic effects of the many aminoglycosides, this is the first study to compare the effects of the most commonly used aminoglycosides i.e., streptomycin, gentamicin, amikacin and netilmicin administered both transtympanically and systemically. The transtympanic and systemic administration of each aminoglycoside caused similar histopathological alterations in the vestibule. The most severe degeneration in the cristae ampullaris, utriculus and sacculus was observed after streptomycine administration. The severity of the vestibular damage in terms of magnitude was in the order of streptomycine, gentamicin, amikacin, and netilmicin.
Amikacin/administration & dosage/*poisoning
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Animals
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Comparative Study
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Gentamicins/administration & dosage/*poisoning
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Guinea Pigs
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Injections, Intraperitoneal
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Netilmicin/administration & dosage/*poisoning
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Streptomycin/administration & dosage/*poisoning
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Tympanic Membrane
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Vestibule/*drug effects
3.Combined regular chemotherapy and lesion management under bronchofiberscope in proliferative endobronchial tuberculosis.
Dong-yuan ZHENG ; Rui ZHOU ; Ping CHEN
Journal of Central South University(Medical Sciences) 2005;30(4):492-493
Adolescent
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Adult
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Aged
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Antitubercular Agents
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administration & dosage
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Bronchitis
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therapy
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Bronchoscopy
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Combined Modality Therapy
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Female
;
Humans
;
Isoniazid
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administration & dosage
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Male
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Microwaves
;
therapeutic use
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Middle Aged
;
Streptomycin
;
administration & dosage
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Tuberculosis, Pulmonary
;
therapy