1.Relationship between Helicobacter pylori seroprevanlence in children and history of digestive disorders in children and their parents
Journal of Medical Research 2007;55(6):141-145
Background: The role of Helicobacter pylori live in digestive tract cause digestive disorder are confirmed. Objectives: To assess the relationship between seroprevalence of Helicobacter pylori (HP) in children and history of digestive disorders in children and their parents. Subjects and method: In this cross-sectional study, history of digestive disorders (recurrent epigastralgy at least 3 episodes in a duration at least 3 months, confirmed either by upper endoscopy or by gastric radiography with contrast or ameloration by treatment with anti - acid) was gathered using questionnaire with additional examination of individual health book, prescription or discharge certificate of a population of 818 children <15 years old in pediatric department, Bach Mai hospital and 369 children <18 in a rural commune. Seroprevalence was determined by ELISA with cut - off at 0.18 optic density. Results:Among in - patients, seroprevalence was 52.6% (20/38) in children with digestive history, significantly higher than 32.6% (254/780) in those who were without this history (p=0.013); risk for HP infection in children with the history was 4.8 higher than that in those who were without the history [OR (95% CI): 4.79 (1.62-9.16)), while the difference in HP seroprevalence was insignificant in children whose mother or father was with or without the history (p > 0.05). Among children in the community, the difference in HP seroprevalence of 72.7% (8/11) in children with and 55.0% (250/373) in those without the history was statistically insignificant (p>0.05). However, HP seroprevalence in children whose father or mother was with the history was of 71.8% (28/39) and 70.5% (31/44), respectivly, significantly higher than 43.1 % (94/318) and 45.6% (125/274) in those whose father or mother was without the history, respectively (p < 0.05). Risk for being HP seropositive in children whose father was with the history was 3.4 folds higher than those whose father was without the history [OR (95% CI): 3.36 (1.38-7.54)] and that in children whose mother was with the history was 2.9 folds higher than in those whose mother was without the history [OR (95% CI): 2.91 (1.41-5.26)]. Conclusion: It exsisted a discrepancy in relationship between HP seroprevalence in children and history of digestive disorders in 2 groups of population in the hospital and in the community, and further studies with larger size were warranted to better clarify this relationship.
Helicobacter pylori/ pathogenicity
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Stomach/ pathology
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Duodenal Diseases/ diagnosis
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pathology
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Child
2.Left Paramedian Abomasopexy in Cattle.
Inhyung LEE ; Norio YAMAGISHI ; Kenji OBOSHI ; Haruo YAMADA
Journal of Veterinary Science 2002;3(1):59-60
Aims of surgery of left displacement of the abomasum (LDA) are to return the abomasum to its original position and create a permanent attachment in the position to prevent recurrence. Left paramedian abomasopexy was performed on six Holstein cows with LDA because normal position of the fundus of the abomasum is located in the left of the midline and the displacement initially only involves the fundus of the abomasum. All cows were recovered without recurrence of LDA. It is considered that the left paramedian abomasopexy could be a major alternative as a surgical treatment of LDA.
Abomasum/abnormalities/*pathology
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Animals
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Cattle
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Cattle Diseases/*pathology
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Stomach Diseases/pathology/surgery/*veterinary
3.Magnifying Endoscopy in Upper Gastrointestinal Tract.
Sang Ho LEE ; Chang Beom RYU ; Jae Young JANG ; Joo Young CHO
The Korean Journal of Gastroenterology 2006;48(3):145-155
For the diagnosis of upper gastrointestinal (GI) lesions, magnification method is usually used in conjunction with chromoscopy, enabling the endoscopist to view subtle mucosal patterns in exquisite detail. Recently published datas have shown that magnifying endoscopy might be a valuable adjunct for the diagnosis, detection, and characterization of inflammatory and neoplastic lesions of the upper GI tract. It is also proven to be an useful surveillance protocol in identifying dysplastic epithelium or early cancer within a segment of Barrett's esophagus. Possible indications for magnifying endoscopy in upper GI tract include screening and surveillance of Barrett's esophagus, defining the extent of esophageal and gastric adenocarcinoma, detecting synchronous/metachronous gastric and esophageal cancers, diagnosing Helicobacter pylori infection, and recognizing minimal mucosal changes in gastroesophageal reflux disease. By grading the quality of evidence for the currently published trials, it is clear that the majority are case series, case reports, and/or observational studies without randomization, control, or blinding. Moreover, other evidence-based criteria such as independent, blind comparisons of magnifying endoscopy with a standard method which evaluates this technology in an appropriate spectrum of patients to whom the test may be applicable, and standardizing methodology would be crucial before magnifying endoscopy becomes a standard procedure in clinical practice. In the future, a uniform classification system for staining and magnifying patterns should be devised and observer agreement should be tested. Futher studies then could be performed based upon consistent, validated, and standardized terminologies and criteria.
Diagnosis, Differential
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Duodenal Diseases/pathology
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Endoscopy, Gastrointestinal/*methods
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Esophageal Diseases/pathology
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Gastrointestinal Diseases/*pathology
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Humans
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Image Enhancement/*methods
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Stomach Diseases/pathology
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Upper Gastrointestinal Tract/pathology
4.Superiority of IV bolus CT in evaluation of metastatic lymphadenopathy in th stomach cancer.
You Song CHANG ; Jae Chun CHANG ; Woo Mok BYUN ; Kil Ho CHO ; Mi Soo HWANG ; Bok Hwan PARK ; Sun Gyo SONG
Journal of the Korean Radiological Society 1993;29(1):111-117
Differentiation of lymph node from vessels or bowel wall with similar clearity is often difficult in conventional contrast-enhanced computed tomography (CCCT). For optimal differentiation of these structures, arterial-phase dominent CT images by IV bolus injection and rapid scan were obtained. The images were compared from those by CCCT in evaluation of lymphadenopathy. Seventy patients, diagnosed as stomach cancer by pathology, were selected for this study. There were 14 cases of equivocal lymphadenopathy on CCCT while IV bolus CT revealed lymphadenopathy in 9 of there and no lymphadenopathy in the rest. Among the 38 cores without lymphadenopathy on CCCT, IV bolus CT detected 4 lymphadenopathy. In 30 node dissection cases, when we decided 1cm as CT criterion for lymphatic enlargement, the sensitivity and the specificity that there were lymphatic enlargement in gross of lymphatic infiltration above one fourth in pathology even though no lymphatic enlargement in gross were 100%. On conclusion, IV bolus CT is more helpful method to evaluate lymphadenopathy than CCCT and compatible with pathologic findings when we decide 1cm as CT criterion for lymphadenopathy. In conclusion, IV bolus CT is superior to CCCT in evaluation of metastatic Lymphadenopathy when using CT Criferion of 1cm as the diameter of enlarged lymph node.
Humans
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Lymph Nodes
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Lymphatic Diseases*
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Methods
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Pathology
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Sensitivity and Specificity
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Stomach Neoplasms*
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Stomach*
5.Low-grade Mucosa-associated Lymphoid Tissue Lymphoma of Stomach.
Sam Ryong JEE ; Sang Young SEOL
The Korean Journal of Gastroenterology 2005;45(5):312-320
Stomach is the most common site of primary extranodal lymphoma. Mucosa-associated lymphoid tissue (MALT) lymphoma is a unique type of extranodal lymphoma which is associated with Helicobacter pylori (H. pylori). The development of low-grade MALT lymphoma of stomach is dependent on H. pylori. A transformed clone carrying the translocation t(11;18)(q21;q21) forms a MALT lymphoma, the growth of which is independent of H. pylori and will not respond to bacterial eradication. And inactivation of the tumor suppressor genes, p53 can lead to high-grade transformation. Endoscopic ultrasound (EUS) is essential to document the extent of disease and is superior to CT scan in the detection of spread to perigastric lymph nodes and follow-up EUS may determine the response to therapy and detect the relapse in early phase. Lesions that are confined to the mucosa or submucosa of gastric wall can be successfully treated with H. pylori eradication. Those low-grade MALT lymphomas that are not H. pylori positive or do not respond to antibiotic therapy can be treated with surgery, radiation, or chemotherapy. Follow-up is critical in all patients who have been treated with H. pylori eradication and consists of multiple endoscopic biopsies and EUS.
Helicobacter Infections/complications
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Helicobacter pylori
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Humans
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*Lymphoma, B-Cell, Marginal Zone/microbiology/pathology
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Stomach Diseases/complications
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*Stomach Neoplasms/microbiology/pathology
6.Bronchogenic cyst in gastric wall.
Wei-ya WANG ; Li-li JIANG ; Wei-ping LIU ; Wen-yan ZHANG
Chinese Journal of Pathology 2005;34(6):380-381
Bronchogenic Cyst
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pathology
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surgery
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Diagnosis, Differential
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Gastrectomy
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methods
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Humans
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Male
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Middle Aged
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Stomach Diseases
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pathology
;
surgery
7.Myoglandular hamartoma of stomach: report of a case.
Jing ZHANG ; Zhao-hui LU ; Tong-hua LIU
Chinese Journal of Pathology 2011;40(12):843-844
Actins
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metabolism
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Adenocarcinoma
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pathology
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Adult
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Diagnosis, Differential
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Endometriosis
;
pathology
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Epithelium
;
pathology
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Female
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Gastrointestinal Stromal Tumors
;
pathology
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Hamartoma
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metabolism
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pathology
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Humans
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Muscle, Smooth
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pathology
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Stomach Diseases
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metabolism
;
pathology
8.Intussusception into the enteroanastomosis after Billroth II gastric resection; diagnosed by gastroscopy.
Woo Ick JANG ; Nam Dong KIM ; Sun Woo BAE ; Won Tsen KIM ; Sang Ok KWON ; Kwang Soo YOON ; Soo Yong KIM
Journal of Korean Medical Science 1989;4(1):51-54
A case of retrograde intussusception (acute type) of efferent limb into Braun side-to-side jejuno-jejunal anastomosis is presented. Intussusception, though infrequent, is well recognized complication after gastric surgery. Patient was 50 year old man who was admitted with epigastric pain and abdominal mass for 6 hours. Patient had a history of total gastrectomy 2 years before admission due to stage II gastric cancer. Seven hours after admission, hematemesis developed. Emergency fiberopticgastroscopy revealed type 4 jejunogastric intussusception. Segmental resection with end-to-end reanastomosis was performed.
Humans
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Intussusception/*etiology/pathology/surgery
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Jejunal Diseases/*etiology/pathology/surgery
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Male
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Middle Aged
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Postoperative Complications/*pathology
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Stomach/*surgery
10.A preliminary clinical study on endoscopic measurement of lesion area with the method of digital image processing technology.
Lei ZHANG ; Zhihua WANG ; Zhongqian FU ; Pengcheng FANG ; Kai LING ; Jianming XU ; Derun KONG ; Zhangwei XU
Journal of Biomedical Engineering 2013;30(5):1091-1096
It is of great importance to measure the lesion area in scientific research and clinical practice. The present study aims to solve barrel distortion and measure lesion area with the technology of computer visualization. With the ultimate purpose to obtain the precise lesion area, the study, based on the original endoscopy system and digital image processing technology, dealt with the correction of barrel distortion by lens adjustment, calculated the gastric ulcer area with the aid of Qt database and finally developed an image processing software--Endoscope Assistant (EAS). The results showed that the EAS was accurate in vitro. It was employed to measure the gastric ulcer area of 45 patients and the results were compared with the traditional formula method. It could be well concluded that this technology is safe, accurate and economical for measuring gastric ulcer area.
Algorithms
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Gastroscopy
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methods
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Humans
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Image Enhancement
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Image Processing, Computer-Assisted
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methods
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Software
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Stomach Diseases
;
diagnosis
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pathology