1.Relationship between Helicobacter pylori seroprevanlence in children and history of digestive disorders in children and their parents
Journal of Medical Research 2007;55(6):141-145
Background: The role of Helicobacter pylori live in digestive tract cause digestive disorder are confirmed. Objectives: To assess the relationship between seroprevalence of Helicobacter pylori (HP) in children and history of digestive disorders in children and their parents. Subjects and method: In this cross-sectional study, history of digestive disorders (recurrent epigastralgy at least 3 episodes in a duration at least 3 months, confirmed either by upper endoscopy or by gastric radiography with contrast or ameloration by treatment with anti - acid) was gathered using questionnaire with additional examination of individual health book, prescription or discharge certificate of a population of 818 children <15 years old in pediatric department, Bach Mai hospital and 369 children <18 in a rural commune. Seroprevalence was determined by ELISA with cut - off at 0.18 optic density. Results:Among in - patients, seroprevalence was 52.6% (20/38) in children with digestive history, significantly higher than 32.6% (254/780) in those who were without this history (p=0.013); risk for HP infection in children with the history was 4.8 higher than that in those who were without the history [OR (95% CI): 4.79 (1.62-9.16)), while the difference in HP seroprevalence was insignificant in children whose mother or father was with or without the history (p > 0.05). Among children in the community, the difference in HP seroprevalence of 72.7% (8/11) in children with and 55.0% (250/373) in those without the history was statistically insignificant (p>0.05). However, HP seroprevalence in children whose father or mother was with the history was of 71.8% (28/39) and 70.5% (31/44), respectivly, significantly higher than 43.1 % (94/318) and 45.6% (125/274) in those whose father or mother was without the history, respectively (p < 0.05). Risk for being HP seropositive in children whose father was with the history was 3.4 folds higher than those whose father was without the history [OR (95% CI): 3.36 (1.38-7.54)] and that in children whose mother was with the history was 2.9 folds higher than in those whose mother was without the history [OR (95% CI): 2.91 (1.41-5.26)]. Conclusion: It exsisted a discrepancy in relationship between HP seroprevalence in children and history of digestive disorders in 2 groups of population in the hospital and in the community, and further studies with larger size were warranted to better clarify this relationship.
Helicobacter pylori/ pathogenicity
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Stomach/ pathology
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Duodenal Diseases/ diagnosis
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pathology
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Child
2.Magnifying Endoscopy in Upper Gastrointestinal Tract.
Sang Ho LEE ; Chang Beom RYU ; Jae Young JANG ; Joo Young CHO
The Korean Journal of Gastroenterology 2006;48(3):145-155
For the diagnosis of upper gastrointestinal (GI) lesions, magnification method is usually used in conjunction with chromoscopy, enabling the endoscopist to view subtle mucosal patterns in exquisite detail. Recently published datas have shown that magnifying endoscopy might be a valuable adjunct for the diagnosis, detection, and characterization of inflammatory and neoplastic lesions of the upper GI tract. It is also proven to be an useful surveillance protocol in identifying dysplastic epithelium or early cancer within a segment of Barrett's esophagus. Possible indications for magnifying endoscopy in upper GI tract include screening and surveillance of Barrett's esophagus, defining the extent of esophageal and gastric adenocarcinoma, detecting synchronous/metachronous gastric and esophageal cancers, diagnosing Helicobacter pylori infection, and recognizing minimal mucosal changes in gastroesophageal reflux disease. By grading the quality of evidence for the currently published trials, it is clear that the majority are case series, case reports, and/or observational studies without randomization, control, or blinding. Moreover, other evidence-based criteria such as independent, blind comparisons of magnifying endoscopy with a standard method which evaluates this technology in an appropriate spectrum of patients to whom the test may be applicable, and standardizing methodology would be crucial before magnifying endoscopy becomes a standard procedure in clinical practice. In the future, a uniform classification system for staining and magnifying patterns should be devised and observer agreement should be tested. Futher studies then could be performed based upon consistent, validated, and standardized terminologies and criteria.
Diagnosis, Differential
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Duodenal Diseases/pathology
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Endoscopy, Gastrointestinal/*methods
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Esophageal Diseases/pathology
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Gastrointestinal Diseases/*pathology
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Humans
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Image Enhancement/*methods
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Stomach Diseases/pathology
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Upper Gastrointestinal Tract/pathology
3.Bronchogenic cyst in gastric wall.
Wei-ya WANG ; Li-li JIANG ; Wei-ping LIU ; Wen-yan ZHANG
Chinese Journal of Pathology 2005;34(6):380-381
Bronchogenic Cyst
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pathology
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surgery
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Diagnosis, Differential
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Gastrectomy
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methods
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Humans
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Male
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Middle Aged
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Stomach Diseases
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pathology
;
surgery
4.A Case of Synchronous Intestinal Tuberculosis Involving the Stomach and Colon.
Joo Hyoung KIM ; Yong Cheol JEON ; Tae Yeob KIM ; Chang Soo EUN ; Joo Hyun SOHN ; Dong Soo HAN ; Jae Jung JANG ; Yong Wook PARK
The Korean Journal of Gastroenterology 2008;52(5):320-324
Intestinal tuberculosis is a common disease of extrapulmonary tuberculosis and should be differentiated from the inflammatory bowel diseases and malignancy such as Crohn's disease, ulcerative colitis, amebic colitis, and colon cancer. Most frequently involved sites (75% of cases) are the terminal ileum and cecum. Other sites of involvement, in order of frequency, are ascending colon, jejunum, appendix, duodenum, stomach, esophagus, sigmoid colon, and rectum. Intestinal tuberculosis simultaneously involving the stomach and colon has been very rarely reported. Recently, we experienced a case of synchronous gastric and colonic ulcers with granulomatous inflammation. Although we did not find acid fast bacilli and the culture test was negative, empirical anti-tuberculosis therapy resulted in dramatic clinical and endoscopic improvement. We report a rare case of multifocal gastrointestinal tuberculosis with a review of literature.
Colonic Diseases/*diagnosis/pathology
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Colonoscopy
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Drug Therapy, Combination
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Female
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Gastroscopy
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Humans
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Middle Aged
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Stomach Diseases/*diagnosis/pathology
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Tomography, X-Ray Computed
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Tuberculosis, Gastrointestinal/*diagnosis/drug therapy/pathology
6.Localized Gastric Amyloidosis.
Yun Nah LEE ; Su Jin HONG ; Hee Kyung KIM
The Korean Journal of Gastroenterology 2011;58(2):117-120
7.Myoglandular hamartoma of stomach: report of a case.
Jing ZHANG ; Zhao-hui LU ; Tong-hua LIU
Chinese Journal of Pathology 2011;40(12):843-844
Actins
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metabolism
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Adenocarcinoma
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pathology
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Adult
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Diagnosis, Differential
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Endometriosis
;
pathology
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Epithelium
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pathology
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Female
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Gastrointestinal Stromal Tumors
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pathology
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Hamartoma
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metabolism
;
pathology
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Humans
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Muscle, Smooth
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pathology
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Stomach Diseases
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metabolism
;
pathology
8.A preliminary clinical study on endoscopic measurement of lesion area with the method of digital image processing technology.
Lei ZHANG ; Zhihua WANG ; Zhongqian FU ; Pengcheng FANG ; Kai LING ; Jianming XU ; Derun KONG ; Zhangwei XU
Journal of Biomedical Engineering 2013;30(5):1091-1096
It is of great importance to measure the lesion area in scientific research and clinical practice. The present study aims to solve barrel distortion and measure lesion area with the technology of computer visualization. With the ultimate purpose to obtain the precise lesion area, the study, based on the original endoscopy system and digital image processing technology, dealt with the correction of barrel distortion by lens adjustment, calculated the gastric ulcer area with the aid of Qt database and finally developed an image processing software--Endoscope Assistant (EAS). The results showed that the EAS was accurate in vitro. It was employed to measure the gastric ulcer area of 45 patients and the results were compared with the traditional formula method. It could be well concluded that this technology is safe, accurate and economical for measuring gastric ulcer area.
Algorithms
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Gastroscopy
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methods
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Humans
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Image Enhancement
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Image Processing, Computer-Assisted
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methods
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Software
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Stomach Diseases
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diagnosis
;
pathology
9.Serial Episodes of Gastric and Cecal Perforation in a Patient with Behcet's Disease Involving the Whole Gastrointestinal Tract: A Case Report.
Dong Yeob SHIN ; Jae Hee CHEON ; Jae Jun PARK ; Hoguen KIM ; Tae Il KIM ; Yong Chan LEE ; Nam Kyu KIM ; Won Ho KIM
The Korean Journal of Gastroenterology 2009;53(2):106-110
Behcet's disease (BD) has been recognized as multi-systemic chronic vasculitic disorder of recurrent inflammation, characterized by the involvement of multiple organs and resulting in orogenital ulcers, uveitis, and skin lesions. Involvement of the central nervous system, vessels, and intestines in BD often leads to a poor prognosis. Digestive manifestations in BD have been reported in up to 1-60% of cases, although the rate varies in different countries. The most frequent extra-oral sites of gastrointestinal involvement are the ileocecal region and the colon. Gastric or esophageal involvement is reported to be very rare. Moreover, there have been no reports on the simultaneous involvement of the esophagus, stomach, ileum, and colon. Here, we present a 55-year-old Korean man with intestinal BD and multiple ileal and colonic ulcerations complicated by perforation, gastric ulcer with bleeding followed by perforation, and esophageal ulcers with bleeding.
Behcet Syndrome/complications/*diagnosis/pathology
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Cecal Diseases/complications/pathology
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Diagnosis, Differential
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Endoscopy, Digestive System
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Gastrointestinal Diseases/complications/*diagnosis
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Gastrointestinal Hemorrhage
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Humans
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Intestinal Perforation/*diagnosis/etiology/pathology
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Male
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Middle Aged
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Peptic Ulcer Perforation/pathology
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Stomach Ulcer/complications/pathology
10.Balantidiasis in the gastric lymph nodes of Barbary sheep (Ammotragus lervia): an incidental finding.
Ho Seong CHO ; Sung Shik SHIN ; Nam Yong PARK
Journal of Veterinary Science 2006;7(2):207-209
A 4-year-old female Barbary sheep (Ammotragus lervia) was found dead in the Gwangju Uchi Park Zoo. The animal had previously exhibited weakness and lethargy, but no signs of diarrhea. The carcass was emaciated upon presentation. The main gross lesion was characterized by severe serous atrophy of the fat tissues of the coronary and left ventricular grooves, resulting in the transformation of the fat to a gelatinous material. The rumen was fully distended with food, while the abomasum evidenced mucosal corrugation with slight congestion. Microscopic examination revealed the presence of Balantidium coli trophozoites within the lymphatic ducts of the gastric lymph node and the abdominal submucosa. On rare occasions, these organisms may invade extra-intestinal organs, in this case the gastric lymph nodes and abomasum.
Abomasum/parasitology
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Animals
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Atrophy/pathology/veterinary
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Balantidiasis/diagnosis/*veterinary
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Balantidium/*isolation&purification
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Female
;
Heart Diseases/pathology/veterinary
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Lymph Nodes/*parasitology
;
Sheep
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Sheep Diseases/diagnosis/*parasitology
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Stomach/*immunology/parasitology