1.Clinics in diagnostic imaging (144). Lateral meniscal ossicle.
Steven B S WONG ; Theresa L C LEE ; Bruce B FORSTER ; Gordon T ANDREWS
Singapore medical journal 2013;54(2):108-quiz 113
A 35-year-old female patient with previous left knee anterior cruciate ligament repair for a skiing injury presented six years later with a traumatic lateral patellar subluxation. Radiographs and magnetic resonance imaging of her left knee joint showed an ossific structure in the region of the lateral meniscus. This was diagnosed as a meniscal ossicle and confirmed during successful arthroscopic excision. The imaging features of meniscal ossicles are reported.
Adult
;
Anterior Cruciate Ligament
;
surgery
;
Anterior Cruciate Ligament Injuries
;
Arthroscopy
;
Bone and Bones
;
pathology
;
Diagnostic Imaging
;
methods
;
Female
;
Humans
;
Knee Joint
;
diagnostic imaging
;
pathology
;
Magnetic Resonance Imaging
;
Menisci, Tibial
;
diagnostic imaging
;
pathology
;
Postoperative Complications
;
Radiographic Image Interpretation, Computer-Assisted
;
Tibial Meniscus Injuries
2.Dose-volume histogram parameters and patient-reported EPIC-Bowel domain in prostate cancer proton therapy
Gabriella F. BULMAN ; Ronik S. BHANGOO ; Todd A. DEWEES ; Molly M. PETERSEN ; Cameron S. THORPE ; William W. WONG ; Jean Claude M. RWIGEMA ; Thomas B. DANIELS ; Sameer R. KEOLE ; Steven E. SCHILD ; Carlos E. VARGAS
Radiation Oncology Journal 2021;39(2):122-128
Purpose:
To analyze rectal dose and changes in quality of life (QOL) measured with the Expanded Prostate and Cancer Index Composite (EPIC) bowel domain in patients being treated for prostate cancer with curative-intent proton beam therapy (PBT) within a large single-institution prospective registry.
Materials and Methods:
Data was collected from 243 patients with localized prostate cancer treated with PBT from 2016 to 2018. The EPIC survey was administered at baseline, end-of-treatment, 3, 6, and 12 months, then annually. Dose-volume histogram (DVH) parameters for the rectum were computed, and rectal dose was analyzed using BED (α/β = 3), EQD2Gy, and total dose. Repeated measures mixed models were implemented to determine the effect of patient, clinical, and treatment factors (including DVH) on patient-reported bowel symptom burden (EPIC-Bowel).
Results:
Treatment overall resulted in changes in EPIC-Bowel scores (baseline score = 93.7), most notably at end-of-treatment (90.6) and 12 months (89.7). However, they returned to baseline at 36 months (92.9). On multivariate modeling, rectal BED D25 (Gy) ≥23% was significantly associated with decline in QOL scores measuring bother (p < 0.01; 4.06 points different).
Conclusion
Rectal doses, specifically BED D25 (Gy) ≥23%, are significantly associated with decline in bowel bother-related QOL in patients undergoing definitive radiotherapy for localized prostate cancer. This study demonstrates BED as an independent predictor of bowel QOL across dose fractionations of PBT.
3.Dose-volume histogram parameters and patient-reported EPIC-Bowel domain in prostate cancer proton therapy
Gabriella F. BULMAN ; Ronik S. BHANGOO ; Todd A. DEWEES ; Molly M. PETERSEN ; Cameron S. THORPE ; William W. WONG ; Jean Claude M. RWIGEMA ; Thomas B. DANIELS ; Sameer R. KEOLE ; Steven E. SCHILD ; Carlos E. VARGAS
Radiation Oncology Journal 2021;39(2):122-128
Purpose:
To analyze rectal dose and changes in quality of life (QOL) measured with the Expanded Prostate and Cancer Index Composite (EPIC) bowel domain in patients being treated for prostate cancer with curative-intent proton beam therapy (PBT) within a large single-institution prospective registry.
Materials and Methods:
Data was collected from 243 patients with localized prostate cancer treated with PBT from 2016 to 2018. The EPIC survey was administered at baseline, end-of-treatment, 3, 6, and 12 months, then annually. Dose-volume histogram (DVH) parameters for the rectum were computed, and rectal dose was analyzed using BED (α/β = 3), EQD2Gy, and total dose. Repeated measures mixed models were implemented to determine the effect of patient, clinical, and treatment factors (including DVH) on patient-reported bowel symptom burden (EPIC-Bowel).
Results:
Treatment overall resulted in changes in EPIC-Bowel scores (baseline score = 93.7), most notably at end-of-treatment (90.6) and 12 months (89.7). However, they returned to baseline at 36 months (92.9). On multivariate modeling, rectal BED D25 (Gy) ≥23% was significantly associated with decline in QOL scores measuring bother (p < 0.01; 4.06 points different).
Conclusion
Rectal doses, specifically BED D25 (Gy) ≥23%, are significantly associated with decline in bowel bother-related QOL in patients undergoing definitive radiotherapy for localized prostate cancer. This study demonstrates BED as an independent predictor of bowel QOL across dose fractionations of PBT.
4.Clinics in diagnostic imaging (150).
Nor Azam MAHMUD ; Dinesh R SINGH ; Steven B S WONG ; Wilfred C G PEH
Singapore medical journal 2013;54(12):666-672
Spontaneous spinal epidural haematoma is a rarely encountered cause of back pain. It often leads to cauda equina syndrome, necessitating emergency spinal surgery. We report the case of a 19-year-old Chinese man who presented with pain in the lower back, which started after he had carried some heavy boxes. He denied a history of fall or trauma. Magnetic resonance (MR) imaging showed a hyperintense biconvex-shaped lesion in the posterior epidural space on both T1- and T2-weighted sequences, diagnostic of a spinal epidural haematoma. The patient, who was admitted and managed conservatively, had gradual resolution of his pain. No neurological deficit was detected on discharge or on follow-up. Repeat MR imaging showed total resolution of the lumbar spinal epidural haematoma. The clinical characteristics, MR imaging features, diagnosis and management of spontaneous spinal epidural haematoma are discussed.
Adult
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Edema
;
diagnosis
;
pathology
;
Female
;
Hematoma, Epidural, Spinal
;
diagnosis
;
pathology
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Humans
;
Low Back Pain
;
diagnosis
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Polyradiculopathy
;
diagnosis
;
Young Adult