Solid pseudopapillary neoplasm (SPN) is a rare tumor that can complicate pregnancy. More
than its rarity, SPNs are unique neoplasms because of their obscure histogenesis, cytology,
immunohistochemical profile, and imaging characteristics. This report describes the case of
a 32‑year‑old gravida 2 para 1 (1001) seen at 24 weeks with an intra‑abdominal mass. The
patient presented with a long-standing history of abdominal mass with the working impression of
gastrointestinal stromal tumor. We employed a multidisciplinary approach to closely monitor tumor
growth, ensure maternal and fetal well-being, avert complications, and avoid unnecessary clinical
interventions. Histopathological evaluation and immunohistochemistry studies of representative
specimens taken at the time of delivery revealed the diagnosis of SPN of the pancreas. Based on
a review of local search engine databases, this is the first documented case of SPN complicating
pregnancy in the Philippines.
Pregnancy