1.Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors.
Shenghua GAO ; Tianguang HUANG ; Letian SONG ; Shujing XU ; Yusen CHENG ; Srinivasulu CHERUKUPALLI ; Dongwei KANG ; Tong ZHAO ; Lin SUN ; Jian ZHANG ; Peng ZHAN ; Xinyong LIU
Acta Pharmaceutica Sinica B 2022;12(2):581-599
Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection. Herein, we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective.