Protein S deficiency is a rare blood disorder associated with an increased risk of thrombosis. Only a few cases of arterial thrombosis of digestive tract have been noted. We report a case of celiac arterial thrombosis and splenic infarction in 46-year-old male with protein S deficiency. Abdominal computed tomography and angiography revealed thrombotic obstruction of the proximal celiac and common hepatic artery with splenic infarction. His total and free antigen of protein S were normal, however, the activity of protein S was low. Percutaneous transluminal angioplasty was performed to revascularise celiac and common hepatic artery.
*Celiac Artery/radiography ; Humans ; Male ; Middle Aged ; Protein S Deficiency/*complications/genetics ; Splenic Infarction/etiology/*radiography ; Thrombosis/etiology/*radiography ; Tomography, Spiral Computed

We report a rare case of aneurysm of splenic artery arising anomalously from the superior mesenteric artery (SMA). The aneurysm was treated successfully by coil embolization of the splenic artery distal to aneurysm and then deploying a stent graft in the SMA. A combination of stent graft and coil embolization for the treatment of aberrant splenic artery aneurysm has been reported only once. We describe the imaging findings and the endovascular procedure in this patient.
Adult ; Aneurysm/radiography/*surgery ; Angiography/*methods ; *Blood Vessel Prosthesis ; Endovascular Procedures/*methods ; Humans ; Male ; Mesenteric Artery, Superior/radiography/*surgery ; *Splenic Artery ; *Stents ; Tomography, X-Ray Computed/*methods ; Treatment Outcome

OBJECTIVETo summarize the clinical feature of splenic artery aneurysms (SAA) in OLT recipient, and review the experience in diagnosis and management.

METHODSThe clinical data, results of four-phase CT scanning and CT angiography of 450 recipients, who underwent OLT from December 2001 to December 2003 were analyzed statistically.

RESULTSTwenty of 450 recipients were diagnosed as SAA, the incidence was about 4.4%. Nineteen of them were diagnosed by four-phase CT scanning. Fifteen patients did not receive any treatment for SAA during OLT, but two of them suffered SAA rupture after OLT, among which one died of hemorrhagic shock although emergency operations were performed. The five patients, who were performed splenectomy with SAA resection during transplantation, recovered successfully after OLT, and their grafts' function was satisfactory.

CONCLUSIONSMorbidity of SAA is higher in patients of liver cirrhosis. Four-phase CT scanning can diagnose SAA exactly. In the early period post-OLT, SAA rupture happens frequently, so SAA resection should be performed during transplantation.

Adolescent ; Adult ; Aged ; Aneurysm ; diagnostic imaging ; surgery ; Female ; Follow-Up Studies ; Humans ; Liver Transplantation ; Male ; Middle Aged ; Radiography ; Retrospective Studies ; Rupture, Spontaneous ; surgery ; Splenic Artery ; Treatment Outcome ; Young Adult

No abstract available.
Biopsy ; Blood Glucose/metabolism ; C-Peptide/blood ; Calcium Gluconate/administration & dosage/*diagnostic use ; Female ; Humans ; Immunohistochemistry ; Injections, Intra-Arterial ; Insulin/blood ; Insulinoma/blood/*blood supply/pathology/surgery ; Middle Aged ; Pancreatic Neoplasms/blood/*blood supply/pathology/surgery ; Pancreaticoduodenectomy ; Splenic Artery/*radiography ; *Tomography, X-Ray Computed ; Treatment Outcome ; Tumor Markers, Biological/blood