Massage is generally accepted as a safe and a widely used modality for various conditions, such as pain, lymphedema, and facial palsy. However, several complications, some with devastating results, have been reported. We introduce a case of a 43-year-old man who suffered from tetraplegia after a neck massage. Imaging studies revealed compressive myelopathy at the C6 level, ossification of the posterior longitudinal ligament (OPLL), and a herniated nucleus pulposus (HNP) at the C5-6 level. After 3 years of rehabilitation, his motor power improved, and he is able to walk and drive with adaptation. OPLL is a well-known predisposing factor for myelopathy in minor trauma, and it increases the risk of HNP, when it is associated with the degenerative disc. Our case emphasizes the need for additional caution in applying manipulation, including massage, in patients with OPLL; patients who are relatively young (i.e., in the fifth decade of life) are not immune to minor trauma.
Adult ; Facial Paralysis ; Humans ; Longitudinal Ligaments ; Lymphedema ; Massage ; Neck ; Ossification of Posterior Longitudinal Ligament ; Quadriplegia ; Spinal Cord ; Spinal Cord Compression ; Spinal Cord Diseases ; Spinal Cord Injuries

Paroxysmal sensorimotor phenomena of the spinal cord have been associated with contrast material injection, transverse myelitis, spinal cord injury and multiple sclerosis. We report a 48-year-old woman with recurrent tonic spasms, which occurred 1 month after acute cervical cord myelopathy. A tingling sensation beginning in the left leg was followed by painful tonic spasm and abnormal sensation of the upper and lower right limbs except the face. Consciousness, scalp EEG was normal and SPECT showed hot uptake in the cervical cord during spasms.
Consciousness ; Electroencephalography ; Extremities ; Female ; Humans ; Leg ; Middle Aged ; Multiple Sclerosis ; Myelitis, Transverse ; Scalp ; Sensation ; Spasm* ; Spinal Cord ; Spinal Cord Diseases* ; Spinal Cord Injuries ; Tomography, Emission-Computed, Single-Photon

Paroxysmal sensorimotor phenomena of the spinal cord have been associated with contrast material injection, transverse myelitis, spinal cord injury and multiple sclerosis. We report a 48-year-old woman with recurrent tonic spasms, which occurred 1 month after acute cervical cord myelopathy. A tingling sensation beginning in the left leg was followed by painful tonic spasm and abnormal sensation of the upper and lower right limbs except the face. Consciousness, scalp EEG was normal and SPECT showed hot uptake in the cervical cord during spasms.
Consciousness ; Electroencephalography ; Extremities ; Female ; Humans ; Leg ; Middle Aged ; Multiple Sclerosis ; Myelitis, Transverse ; Scalp ; Sensation ; Spasm* ; Spinal Cord ; Spinal Cord Diseases* ; Spinal Cord Injuries ; Tomography, Emission-Computed, Single-Photon

No abstract available.
Neuralgia ; Spinal Cord Compression ; Spinal Cord Diseases

STUDY DESIGN: Prospective study conducted at Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, India. PURPOSE: To show the efficacy of decompression in the late presentation of cervical spinal cord disorders. OVERVIEW OF LITERATURE: Studies by various authors have shown that early spinal decompression results in better neurological outcomes. METHODS: From January 2003 to January 2005, 11 of the 41 patients with cervical spinal cord compression, meeting the inclusion criteria, underwent anterior decompression; interbody graft placement and stabilization by anterior cervical locking plate. The neurologic and functional outcomes were recorded. RESULTS: Five patients had spinal cord injury and 6 patients had compressive cervical myelopathy. Complications included 1 death and 1 plate loosening. No patient lost their preoperative neurological status. One patient had no improvement, 2 patients showed full recovery. The mean follow-up is 28.3 month. At the of rehabilitation, 6 were able to walk without support), 2 could walk with support, and 1 needed a wheelchair. The average American Spinal Injury Association motor score on admission to the hospital, 32.8 (standard deviation [SD], 30.5); admission to rehabilitation, 38.6 (SD, 32.4); discharge from rehabilitation, 46.2 (SD, 33.7). The most recent follow-up was 64.0 (SD, 35.3). CONCLUSIONS: The anterior approach for cervical decompression allows for adequate decompression. This decompression is the best chance offered in even late reported cases, including posttraumatic cases where there is no evidence of cord transactions. The use of anterior cervical plates reduces the chances of graft loosening, extruding, or collapsing.
Cervical Vertebrae ; Decompression* ; Decompression, Surgical ; Female ; Follow-Up Studies ; Humans ; India ; Neglected Diseases ; Prospective Studies ; Quadriplegia ; Rehabilitation ; Spinal Cord Compression ; Spinal Cord Diseases* ; Spinal Cord Injuries ; Spinal Cord* ; Spinal Injuries ; Transplants ; Wheelchairs

It is very difficult to differentiate radiation myelopathy from metastatic intramedullary spinal cord tumor. We described a case of chronic progressive radiation myelopathy, in which serial magnetic resonance imaging was of great value for the differential diagnosis.
Diagnosis, Differential ; Magnetic Resonance Imaging* ; Radiation Injuries ; Spinal Cord Diseases* ; Spinal Cord Neoplasms

An inflammatory myofibroblastic tumor (IMT) is a rare disease entity reported to arise in various organs. It is thought to be a neoplastic or reactive inflammatory condition, controversially. The treatment of choice for myofibroblastic tumor is surgery, and recurrence is known to be rare. The optimal treatment method is not well-known for patients ineligible for surgery. We report a 47-year-old patient with aggressive recurrent IMT of the lungs. The patient had been admitted for an evaluation of back-pain two years after a complete resection of pulmonary IMT. Radiation therapy was performed for multiple bone recurrences, and the symptoms were improved. However the patient presented again with aggravated back-pain six months later. High-dose steroid and non-steroidal anti-inflammatory drugs were administered, but the disease progressed aggressively, resulting in spinal cord compression and metastasis to intra-abdominal organs. This is a very rare case of aggressively recurrent pulmonary IMT with multi-organ metastasis.
Humans ; Lung ; Lung Neoplasms ; Middle Aged ; Myofibroblasts* ; Neoplasm Metastasis* ; Rare Diseases ; Recurrence ; Spinal Cord Compression

STUDY DESIGN: Prospective case series. PURPOSE: To analyze the demographic picture of the patients suffering from compression myelopathy due to various spinal problems. Overview of Literature: There is a lack of literature depicting demographic picture of such patients with spinal injuries as most of the articles have shown the epidemiology of spinal cord injuries either managed conservatively or operatively. None have focused on the patients with compressive myelopathy requiring surgeries. METHODS: Patients with spinal pathologies with a neurological deficit due to compressive myelopathy requiring surgical decompression of dorsal and thoracolumbar region were studied. The different kinds of etiologies, the demographic profiles involved, the involvement of various regions of spine in each of the etiologies, sex distribution of different etiologies, association of age and sex with the occurrence of paraplegia, and association of thoracolumbar junction (TLJ) involvement by age and sex were studied. This study addressed the dorsal and TLJ till L2 vertebrae surgically treated by anterior transthoracic transpleural approach. RESULTS: With regard to gender, 75% of the females and 67.3% of the males were paraplegic but there was no relationship between gender and the occurrence of paraplegia (p >0.05). There was also no association between TLJ involvement and the age and sex of the patients (p >0.05). Seventy percent of the patients were paraplegic with a mean age of 38.90 years and 30% were paraparetic with a mean age of 43.43 years. Male to female ratio stood at 4.43:1. CONCLUSIONS: Traumatic spine in females is increasing. The occurrence of paraplegia and involvement of TLJ is not affected by the age and the sex of the patients. Deep epidemiological understanding of spinal pathologies can lead to a better appreciation of the potential impact of health care management strategies and health policies to prevent and minimize their consequences considering limited worldwide reports on the same.
Asian Continental Ancestry Group* ; Decompression, Surgical ; Delivery of Health Care ; Demography ; Epidemiology ; Female ; Health Policy ; Humans ; Male ; Paraplegia ; Pathology ; Prospective Studies ; Sex Distribution ; Spinal Cord Compression* ; Spinal Cord Diseases ; Spinal Cord Injuries ; Spinal Injuries ; Spine

No abstract available.
Humans ; Hypoparathyroidism* ; Ligamentum Flavum* ; Spinal Cord Compression* ; Spinal Cord Diseases

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is characterized by progressive death of motor neurons in the cortex, brainstem, and spinal cord. Until now, many treatment strategies have been tested in ALS, but so far only Riluzole has shown efficacy of slightly slowing disease progression. The pathophysiological mechanisms underlying ALS are multifactorial, with a complex interaction between genetic factors and molecular pathways. Other motor neuron disease such as spinal muscular atrophy (SMA) and spinobulbar muscular atrophy (SBMA) are also progressive neurodegenerative disease with loss of motor neuron as ALS. This common thread of motor neuron loss has provided a target for the development of therapies for these motor neuron diseases. A better understanding of these pathogenic mechanisms and the potential pathological relationship between the various cellular processes have suggested novel therapeutic approaches, including stem cell and genetics-based strategies, providing hope for feasible treatment of ALS.
Amyotrophic Lateral Sclerosis* ; Brain Stem ; Disease Progression ; Hope ; Motor Neuron Disease ; Motor Neurons ; Muscular Atrophy, Spinal ; Muscular Disorders, Atrophic ; Neurodegenerative Diseases ; Riluzole ; Spinal Cord ; Stem Cells