Anti-Müllerian hormone (AMH) is now accepted as an important clinical marker of ovarian reserve and is increasingly measured as an initial evaluation at infertility clinics. The aim of this study was to establish reference values for the revised second generation (Gen II) assay using population-based data. In this population-based cohort study, AMH data from unselected infertile women aged 25–45 years from June 2013 to June 2014 (n = 15,801) were collected. The AMH values were measured using the revised Gen II assay. We established and validated 5 AMH-age regression models. Based on the optimal AMH-age model, reference values and centile charts were obtained. The quadratic model (log AMH = 0.410 × age − 0.008 × age²− 3.791) was the most appropriate for describing the age-dependent decrease in AMH measured using the revised Gen II assay. This is the largest population-based study to establish age-specific reference values of AMH using the revised Gen II assay. These reference values may provide more specific information regarding the ovarian reserve estimation of infertile women.
Biomarkers ; Cohort Studies ; Female ; Humans ; Infertility ; Ovarian Reserve ; Reference Values*

PURPOSE: The purpose of this study was to describe cleaning workers' working experiences in Korea. METHODS: The data were collected in two focus-group interviews with 9 cleaning workers. The phenomenological analytic method suggested by Colaizzi was used to analyze the data. RESULTS: Five theme clusters and thirteen themes emerged from the analysis. The first theme clusters, 'Dead-end choice' included Limits of elderly women workers, Financial difficulties, Lowered self-esteem. The second theme clusters, 'Facing with discriminatory working environments' included Fear and unfair working conditions. The third theme clusters, 'Potential health problems' included Physical overload, Repeated exposure to hazardous substances and Emotional labor. The fourth theme clusters, 'Excluded from protection of the law' included Gloomy reality and Sexual harassment. The fifth theme clusters, 'Desire to get out of social isolation' included Efforts to maintain the status, Desire to live confidently and Desire to change social recognition. CONCLUSION: The findings of the study provide understanding on cleaning workers' working experiences to explain by their vision and language and should ensure proper working conditions and environment to live a better life.
Aged ; Female ; Focus Groups ; Hazardous Substances ; Humans ; Interviews as Topic ; Korea ; Occupational Health Nursing ; Qualitative Research ; Sexual Harassment ; Women, Working

BACKGROUND: Primary human cytomegalovirus (CMV) infection during pregnancy is a major cause of congenital malformation. We detected primary CMV infection in pregnant Korean women by using an algorithm that comprises CMV IgG, IgM, and IgG avidity tests. METHODS: During a 2-month period, 744 pregnant women who were at 10-19 weeks of gestation were consecutively enrolled in this study. Human anti-CMV IgG and IgM levels in their sera were determined by chemiluminescence immunoassays. Serum samples from the women who were positive for CMV IgG and IgM were assayed by the ARCHITECT CMV IgG avidity test in order to distinguish primary from non-primary CMV infection. Gross examination of the neonates of the women who were positive for CMV IgM was conducted. RESULTS: The seroprevalence of CMV IgG and IgM was estimated to be 98.1% and 1.7%, respectively. The samples from all the women who were positive for CMV IgM or with grey zone results contained high avidity CMV IgG. Seven women with positive CMV IgG and IgM results who completed follow-up up to delivery showed no gross evidence of in utero CMV transmission. CONCLUSIONS: Maternal primary CMV infection was not detected in any of the pregnant women included in this study cohort. CMV IgG avidity test enabled the identification of women who were at a low risk of transmitting CMV infection and provided informative for subsequent pregnancy outcomes. Compared to previous studies, the seroprevalence of CMV IgG antibody across pregnant Korean women remained unchanged.
Adult ; Antibodies, Viral/*blood ; Asian Continental Ancestry Group ; Chemiluminescent Measurements ; Cytomegalovirus/*immunology ; Cytomegalovirus Infections/*diagnosis/epidemiology ; Enzyme-Linked Immunosorbent Assay ; Female ; Gestational Age ; Humans ; Immunoglobulin G/*blood ; Immunoglobulin M/blood ; Pregnancy ; Pregnancy Complications, Infectious/*diagnosis/epidemiology ; Republic of Korea ; Seroepidemiologic Studies ; Young Adult

OBJECTIVES: This study was conducted to evaluate the nutrition quotient (NQ) by mother's parenting style which may influence the NQ in preschool children. METHODS: Subjects were 310 mothers and their 4-6 year old children. The questionnaire composed of demographic characteristics, mother's parenting style at meal time and eating behavior as measured by NQ questions. The NQ questions consisted of 19 food behavior checklist items and all items were grouped into 5 factors: balance, diversity, moderation, regularity, and practice. Mother's parenting style was classified by using words for nutrition education at meal time. All data were statistically analyzed by SPSS program (Ver. 23) and the statistical differences in variables were evaluated by Student's t-test, χ²-test, One-way ANOVA. RESULTS: We observed that in children whose mothers use the parenting style at meal time of ‘explanation’ and ‘compliment & cheer up’ had high dietary regularity, diversity, practice. The children of mothers who use the parenting style at meal time of ‘persuasion’ and ‘reward’ were found to have a lower degree of balance, diversity, and practice. Especially, children of ‘reward’ style mothers had lower moderation of dietary life. On the other hand, among the parenting style at meal time of ‘comparison & demand’, ‘treating’ and ‘faire’, there was no significant difference in the NQ factor by each group. NQ grade was higher among those who used more explanation (p < 0.001) and persuasion (p < 0.01) and with use of less persuasion (p < 0.01) and reward (p < 0.01). The positive association observed between the frequency of dietary education of mothers and higher NQ grade indicated the degree of dietary practices of those children. On the other hand, the children of mothers who rarely practice the dietary education at home had lower NQ grade (p < 0.001). CONCLUSIONS: In order to promote children's proper dietary behaviors, it is important to provide nutrition education to children as well as provide guidance on parenting style at meal time.
Checklist ; Child ; Child, Preschool ; Education ; Feeding Behavior ; Hand ; Humans ; Meals* ; Mothers ; Parenting* ; Parents* ; Persuasive Communication ; Reward

Purpose: To evaluate the effects of the non-invasive keratograph break-up time on the repeatability of keratometric measurements derived using the Keratograph 5M in patients with dry eye syndrome. Methods: Thirty-six patients with dry eye and 30 controls were enrolled. We measured keratometric values twice in all subjects and explored whether the two measurements differed by more than 0.5 diopter (D) (the absolute value). We also evaluated the relationship between the absolute difference and the non-invasive keratograph break-up time (NIKBUT). Results: The intraclass correlation coefficients for astigmatism, flat keratometry (K), steep K, and mean K were all higher than 0.95 in patients, thus lower than in controls. The proportion of eyes with absolute differences over 0.5 D between the two keratometric values differed significantly between the dry eye and control groups in terms of the flat K and Kmax values (p = 0.033, 0.037). The average NIKBUT was negatively correlated with the absolute differences in Kmax and astigmatism (p = 0.030, R2 = 0.134 and p = 0.017, R2 = 0.160). Conclusions In patients with dry eye syndrome, keratometric measurements are reliably repeatable, but slightly less so than in normal controls. The proportions of eyes exhibiting absolute keratometric differences over 0.5 D (two measurements) differed in the dry eye and control groups. The lower the non-invasive keratograph break-up time, the poorer the repeatability of keratometric measurements in the dry eye group. Therefore, care is required when obtaining keratometric values for such patients.

Advancements in digital technology have led to increased usage of digital devices among teenagers. The coronavirus disease 2019 pandemic and the subsequent implementation of social distancing policies have further accelerated this change. Consequently, a new concept called the metaverse has emerged. The metaverse is a combination of a virtual reality universe that allows individuals to meet, socialize, work, play, entertain, and create. This review provides an overview of the concept and main features of the metaverse and examples of its utilization in the real world. It also explains the unique developmental characteristics of childhood and adolescence, as well as the possible negative influences of the metaverse on them, including addiction, antisocial behavior, cyberbullying, and identity confusion.This review summarizes several suggestions for future research because the metaverse is a relatively new concept.

This study investigated the healthcare status of South Korea and member states of the Organization for Economic Cooperation and Development (OECD). By employing the position value for relative comparison index, healthcare status was measured through the following components: demand, supply, accessibility, quality, and cost. Statistical analysis was conducted through the Mann-Kendall test from analyzing trends from 2000 onwards. Results showed that while Korea, on average, scores higher than the OECD average in most of the investigated components, it is below average in certain indexes including primary care and mental health care. Considering the various health issues that have been raised about these indexes, it is important these components be improved upon by policy-makers.
Delivery of Health Care ; Health Policy ; Korea ; Mental Health ; Organisation for Economic Co-Operation and Development ; Primary Health Care

PURPOSE: The purpose of this study was to investigate partnerships with nurses, social support and readiness for discharge among mothers of premature infants in the neonatal intensive care unit (NICU) and to examine the factors associated with readiness for discharge.METHODS: A survey was conducted among 85 mothers of premature infants hospitalized in a NICU in Seoul, Korea. The collected data were analyzed with descriptive statistics, the t-test, one-way analysis of variance, Pearson' correlation coefficients, and multiple linear regression using SPSS version 25.0.RESULTS: The results of the regression analysis showed that partnerships with nurses (β=.32, p=.011) and parenting experience (β=.32, p=.001) were significantly associated with readiness for discharge.CONCLUSION: To improve the readiness for discharge among mothers of premature infants, developing strategies to strengthen their partnership with nurses and to provide family-centered care will be needed.
Humans ; Infant, Newborn ; Infant, Premature ; Intensive Care Units, Neonatal ; Intensive Care, Neonatal ; Korea ; Linear Models ; Mothers ; Parenting ; Parents ; Patient Discharge ; Seoul