1.Values of intradermal test and multiple sputum examinations for dagnosis of paragonimiasis.
Joung Soon KIM ; Soung Soon PARK
The Korean Journal of Parasitology 1974;12(2):119-125
This study was conducted on 4,003 inhabitants of six villages, Southern County of Che Ju lsland from April 18 to July 30, 1974 with purpose of studying. Relationship between intradermal reaction and egg detection rate, Egg detection rate by the number of sputum examination on the same subject, Comparison of direct sputum examination method (Whole volume of sputum in vinyl bag pressed between petri dishes) with concentration (2per cent NaOH) method, Estimation of sensitivity and specificity of the intradermal test in screening paragonimiasis. The results obtained are as follows: Overall positive skin reaction rate was 57.7 per cent and egg positive rate regardless of skin reaction was 17.1 per cent the population studied. Egg positive rate for negative skin reactors(wheal size smaller than 70mm(2)) was l0.l per cent, and that of positive reactors was 22.8 per cent. Positive skin reaction rate increased as age increased, egg positive rate, however, revealed rather inconsistent distribution by age. The egg positive rate showed a tendency of increase by increase of wheal size, though not so remarkably. 2.9 per cent of egg positives by direct sputum examination method was negative when re-examined by concentration method; 2.6 per cent of egg negative sputum by direct method was egg positive by concentration method. It was found that the sputa showing discrepant result by two different methods had only a few eggs in whole sputum collected. Egg positive rate by single sputum examination was 8.l per cent, by two examinations 14.6 per cent by three 19.2 per cent, by four 24.5 per cent, and by five examinations on the same individual was 20.5 per cent. The estimated sensitivity and specificity of the skin test were 76.5 per cent and 42.7 per cent respectively under the postulation that all infected persons could be detected by four sputum examinations.
parasitology-helminth-trematoda-Paragonimus westermani
;
skin test
;
sputum
;
sensitivity-specificity
;
diagnosis
2.A Case of Vogt-Koyanagi-Harada Syndrome.
Soung Soo PARK ; Pyung Soon KWARK
Journal of the Korean Ophthalmological Society 1978;19(3):313-317
We have experienced a case of Vogt-Koyanagi-Harada Syndrome in 35 years-old male. The Voght-Koyanagi-Harada Syndrome is characterized by severe chronic bilateral Ilveitis associated with alopecia, poliosis, vitiligo and signs of meningeal irritation. In presented case, there was extensive posteriar synechia, numerous mutton fat K.P. in addition to cataract, poliosis, vitiligo, headache and dysacousia. Steroid was administered over period of 6 monthes in gradual decreasing dosage, but there was no appearent effect on the course of the disease.
Adult
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Alopecia
;
Cataract
;
Headache
;
Humans
;
Male
;
Uveomeningoencephalitic Syndrome*
;
Vitiligo
3.Psychological Study of Dermographism Patients.
Inn Ki CHUN ; Mi Soon PARK ; Soung Hun KIM ; Young Pio KIM
Korean Journal of Dermatology 1987;25(3):318-325
The subjects of the present study was 300 out-patients and 304 people living in similar condition. The SCL-90(symptom check list-90) questionare was used and the two groups were compared by many factors. The rcsults were as follows. 1. All dimensional values of the dermographism group were much higher than the normal group except obsessive-compulsive dimension. The order of significance: Paranoid ideation, interpersonal sensitivity somatization, depression, anxiety, hostility and phobic anxiety(p<0. 01), The result indicates a significantly high incidence of psychological problems among dermographism patients. 2. In the dermographism group, the patients over 30 years old had significantly higher. scores in depression, anxiety, hostility and psychoticism. 3. Male patents showed significantly higher scores than female in paranoid ideation. 4. The unmarried patients had significantly higher scores in dcpression, para noid ideation and psychoticism. 5. Thc longer the duration of the disease was the higher the scores were. 6, There were no significant differences in educational status, family history, the job at onset of the disease, and the accuracy of understanding about the disease.
Adult
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Anxiety
;
Depression
;
Dronabinol
;
Educational Status
;
Female
;
Hostility
;
Humans
;
Incidence
;
Male
;
Outpatients
;
Single Person
4.Development of Standard Digital Images for Pneumoconiosis.
Won Jeong LEE ; Byung Soon CHOI ; Sung Jin KIM ; Choong Ki PARK ; Jai Soung PARK ; Seok TAE ; Kurt Georg HERING
Journal of Korean Medical Science 2011;26(11):1403-1408
We developed the standard digital images (SDIs) to be used in the classification and recognition of pneumoconiosis. From July 3, 2006 through August 31, 2007, 531 retired male workers exposed to inorganic dust were examined by digital (DR) and analog radiography (AR) on the same day, after being approved by our institutional review board and obtaining informed consent from all participants. All images were twice classified according to the International Labour Office (ILO) 2000 guidelines with reference to ILO standard analog radiographs (SARs) by four chest radiologists. After consensus reading on 349 digital images matched with the first selected analog images, 120 digital images were selected as the SDIs that considered the distribution of pneumoconiosis findings. Images with profusion category 0/1, 1, 2, and 3 were 12, 50, 40, and 15, respectively, and a large opacity were in 43 images (A = 20, B = 22, C = 1). Among pleural abnormality, costophrenic angle obliteration, pleural plaque and thickening were in 11 (9.2%), 31 (25.8%), and 9 (7.5%) images, respectively. Twenty-one of 29 symbols were present except cp, ef, ho, id, me, pa, ra, and rp. A set of 120 SDIs had more various pneumoconiosis findings than ILO SARs that were developed from adequate methods. It can be used as digital reference images for the recognition and classification of pneumoconiosis.
Adult
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Aged
;
Aged, 80 and over
;
Dust
;
Humans
;
Lung/*pathology/*radiography
;
Male
;
Middle Aged
;
Occupational Exposure
;
Pleura/radiography
;
Pneumoconiosis/*radiography
;
Radiographic Image Enhancement/*standards
5.Management of the Third Molar Tooth in Mandibular Angle Fracture.
Tae Hwang AN ; Eun Su PARK ; Sang Gu KANG ; Soung Gyun JOUNG ; Young Bae KIM
Journal of the Korean Cleft Palate-Craniofacial Association 2003;4(1):15-18
The management of the third molar tooth in mandibular angle fracture is still controversial. Retrospective analysis of 197 cases of mandibular angle fractures associated with third molar tooth was undertaken. Selective prophylactic extraction of the third molar teeth were undertaken in 66 cases. The third molar teeth were retained in 131 fractures. The indication of extraction of the third molar teeth in mandibular angle fracture were as follows: 1) interfering with reduction of the fracture; 2) excessive mobility; 3) exposure of tooth root due to distraction of the fracture; 4) fractured teeth; 5) severely carious tooth 6) infected supporting structure. There were no significant differences between the complication rate in the "tooth removed" group and "tooth retained" group. Complications were minimal. Therefore proper management of the third molar tooth in mandibular angle fracture will minimize complication.
Molar, Third*
;
Retrospective Studies
;
Tooth Root
;
Tooth*
6.Identification and purification of IgE-reactive proteins in German cockroach extract.
Tai Soon YONG ; Jong Seok LEE ; Jongweon LEE ; Soon Jung PARK ; Soung Hoo JEON ; Han Il REE ; Jung Won PARK
Yonsei Medical Journal 1999;40(3):283-289
Cockroaches have been implicated as a cause of respiratory allergy in urban areas worldwide. IgE-reactive German cockroach proteins were identified with molecular weights (MWs) of 90, 66, 50, 43 and 36 KD by immunoblot analysis in both immune BALB/c mice and sensitized humans. Prominent IgE-reactive proteins were purified using FPLC by ion-exchange chromatography, gel filtration and hydrophobic chromatography. The N-terminal amino acid sequence of a purified protein with a MW of 66 KD on SDS-PAGE was Val-Thr-Leu-Lys-Lys(Val)-Met-Ile-Lys-Thr-Phe-Tyr. No homologous protein was found through a search of GenBank that indicated a novel IgE-reactive protein in German cockroach extract. Another purified protein with a MW of 36 KD reacted strongly with a monoclonal antibody against Bla g 2.
Amino Acid Sequence/genetics
;
Animal
;
Cockroaches/chemistry*
;
Human
;
IgE/immunology*
;
Insect Proteins/isolation & purification*
;
Insect Proteins/immunology*
;
Insect Proteins/genetics
;
Mice
;
Mice, Inbred BALB C
;
Tissue Extracts/chemistry*
7.US-guided Left-sided Percutaneous Biliary Drainage: Analysis of the Technical Factors Related to Procedure.
Young Hwan KIM ; Young Jin PARK ; Su Young KIM ; Soung Hee KIM ; Dong Man PARK ; Yong Hoon KIM ; Soon Joo CHA ; Gham HUR
Journal of the Korean Radiological Society 1998;38(4):679-684
PURPOSE: To evaluate the factors affecting procedure related technical difficulties of US-guided left sidedPTBD and the complications involved in the use of this method. MATERIAL AND METHODS: We prospectively evaluatedUS-guided left PTBD in 26 patients with malignant biliary obstructions. The causes of underlying malignancy werebile duct carcinoma(n=10), adenocarcinoma of the pancreas(n=8), GB carcinoma(n=4), metastasis to the portahepatis(n=2), duodenal carcinoma(n=1), hepatocellular carcinoma(n=1). We divided the procedure into four steps forthe evaluation of technical difficulties, and we measured procedure time and fluoroscopic exposure time. And weevaluated the incidence of procedure related complications. RESULTS: US-guided left PTBD was successful in allattempted cases. The average procedure time and fluoroscopic exposure time involved were 14.2 min. and 5.5 min.,respectively. From the first step to the fourth step, the average time required was 4.4 min, 2.3 min., 1.9 min.,5.6 min., respectively. One major complication involved sepsis(3.8%), and ten minor complications including fivetransient hemobilia(19.2%), three tube malfunction(11.5%), and two fever(7.6%). CONCLUSION: US-guided left PTBDwas easy to perform and a relatively safe method. The total procedure time was short, and as the radiologistbecomes more experienced, this could be further reduced.
Adenocarcinoma
;
Drainage*
;
Humans
;
Incidence
;
Neoplasm Metastasis
;
Prospective Studies
8.Pulmonary Tuberculosis with Airspace Consolidation vs Mycoplasma Pneumonia in Adults: High-Resolution CT Findings.
Chull Hee CHA ; Gyo Chang CHOI ; Jai Soung PARK ; Jung Hwa HWANG ; Kyung Rak KIM ; Han Haek IM ; Dae Ho KIM ; Deuk Lin CHOI
Journal of the Korean Radiological Society 1997;36(2):247-252
PURPOSE: To analyse and compare high-resolution CT findings of pulmonary tuberculosis with consolidation and mycoplasma pneumonia. MATERIALS AND METHODS: Twenty patients with pulmonary tuberculosis [confirmed by sputum culture (n=9) and bronchoscopic biopsy (n=11)] and airspace consolidation on high-resolution CT and 17 patientswith mycoplasma pneumonia, confirmed by serologic test, were included in this study. High-resolution CT findings were analyzed in terms of ground-glass opacities, distribution of consolidation, type of nodules, cavities, interlobular septal thickening, bronchial dilatations, bronchial wall thickening and pleural effusion. RESULTS: In patients with tuberculsis, average age was 33.5 years (range, 20-67) ; in those with mycoplasma pneumonia it was 32.5 years (range, 17-74). Segmental and subsegmental distributions were most common in both diseases ; the preferred site of consolidation was different, however ; for tuberculosis it was the upper lobes (13 cases, 65% ; bilateral involvement, 7 cases) ; for mycoplasma pneumonia it was the lower lobes (11 cases, 64.7%). Non-segmental (diffuse and random) distribution of ground-glass opacities were seen in two patients(11.8%) with mycoplasma pneumonia. Centrilobular nodules, branching linear opacities and alveolar nodules were not different in both diseases, but there were nodules above 10mm in 14 cases of tuberculosis and in only one case of mycoplasma pneumonia. Tree-in-bud appearances were seen in five cases of tuberculosis. Cavities without air-fluid level were noted in ten cases of tuberculosis. Other interlobular septal thickening, bronchial wall thickening, bronchial dilatation and pleural effusion were not different in both diseases. CONCLUSION: There was considerable overlap between high resolution CT findings of tuberculosis with airspace consolidation and those of mycoplasma pneumonia. The location of consolidation, type of nodules, and the presence of tree-in-bud appearance and cavities help in the differentiation of the two diseases, however.
Adult*
;
Biopsy
;
Dilatation
;
Humans
;
Mycoplasma*
;
Pleural Effusion
;
Pneumonia, Mycoplasma*
;
Serologic Tests
;
Sputum
;
Tuberculosis
;
Tuberculosis, Pulmonary*
9.A Case of Drug-Induced Autoimmune Hepatitis after Glucosamine Ingestion.
Seong Soon KWON ; Jee Wan WEE ; Jung Wan PARK ; Seug Yun YOON ; Soung Won JEONG ; Jae Young JANG ; Yoon Mi JIN
Korean Journal of Medicine 2013;85(5):503-506
Herbal remedies and health foods are widely used, and their side effects have been reported. Glucosamine is a naturally occurring amino-monosaccharide and a safe health food; rarely, however, it can cause cholestatic and hepatocellular hepatitis. We describe a case of drug-induced autoimmune hepatitis after ingestion of glucosamine. A middle-aged woman who had no history of liver disease complained of jaundice after taking glucosamine. The diagnosis of drug-induced acute autoimmune hepatitis was made using the Roussel Uclaf Causality Assessment Method score based on the patient's history and laboratory data, and percutaneous liver biopsy. After supportive care and administering prednisolone and azathiprine, the patient showed rapid improvement in clinical symptoms and laboratory findings.
Biopsy
;
Diagnosis
;
Drug-Induced Liver Injury
;
Eating*
;
Female
;
Glucosamine*
;
Food, Organic
;
Hepatitis
;
Hepatitis, Autoimmune*
;
History
;
Humans
;
Jaundice
;
Liver
;
Liver Diseases
;
Prednisolone
10.A Case of Drug-Induced Autoimmune Hepatitis after Glucosamine Ingestion.
Seong Soon KWON ; Jee Wan WEE ; Jung Wan PARK ; Seug Yun YOON ; Soung Won JEONG ; Jae Young JANG ; Yoon Mi JIN
Korean Journal of Medicine 2013;85(5):503-506
Herbal remedies and health foods are widely used, and their side effects have been reported. Glucosamine is a naturally occurring amino-monosaccharide and a safe health food; rarely, however, it can cause cholestatic and hepatocellular hepatitis. We describe a case of drug-induced autoimmune hepatitis after ingestion of glucosamine. A middle-aged woman who had no history of liver disease complained of jaundice after taking glucosamine. The diagnosis of drug-induced acute autoimmune hepatitis was made using the Roussel Uclaf Causality Assessment Method score based on the patient's history and laboratory data, and percutaneous liver biopsy. After supportive care and administering prednisolone and azathiprine, the patient showed rapid improvement in clinical symptoms and laboratory findings.
Biopsy
;
Diagnosis
;
Drug-Induced Liver Injury
;
Eating*
;
Female
;
Glucosamine*
;
Food, Organic
;
Hepatitis
;
Hepatitis, Autoimmune*
;
History
;
Humans
;
Jaundice
;
Liver
;
Liver Diseases
;
Prednisolone