No abstract available.

No abstract available.
Hernia*

The utilization of CT-guided fine needle aspiration biopsy of bone has been the subject of considerable interest, since the introduction of the CT scanning. The CT-guided needle biopsy of 11 consecutive patients with avariety of "Etiology Unknown Spinal Disorders" resulted in a 100% yield of positive tissue diagnosis without significant complicaitons. The main advantage of CT guidance is the continuous direct observation of the needletip position in relation to the target volume, the more precise sampling from smaller and deeper lesion is another advantage. We are confident that localization of pathology by CT is the most accurate method for perform ingbiopses, and thus replaces the conventional ways of approaches and this could be utilized on the other organbiopsy in the future.
Biopsy ; Biopsy, Fine-Needle ; Biopsy, Needle ; Diagnosis ; Humans ; Methods ; Pathology ; Tomography, X-Ray Computed

No abstract available.

No abstract available.
Animals ; Liver* ; Rats* ; Selenium*

BACKGROUND: Elements of informed consent including capacity, disclosure, understanding, voluntariness, and permission of the participant, are all crucial for clinical trials to be legally and ethically valid. During the informed consent process, the patient information leaflet is an important information source which prospective research subjects can utilize in their decision-making. In the adequate provision of information, KGCP guideline necessitate 20 specific items, as well as the use language that individuals can understand. This study measures the vocabulary level of patient information leaflets in an effort to provide an objective evaluation on the readability of such material. METHODS: The word difficulty of 13 leaflets was quantitatively evaluated using Kim kwang Hae's vocabulary grading framework, which was compared to the difficulty level of words found in the 6th grade Korean textbook. The quantitative outcomes were statistically analyzed using chi-squared tests and linear by linear association for ordinal data. RESULTS: There was a statistically significant difference between the vocabulary level and frequency of words in leaflets and the 6th Korean textbook. The leaflets were on average 260 sentences and about roughly 15 pages long, including lay language (easier or equal to language used in primary school) of around 12% less; technical language of around 4.5% more. As the vocabulary grades increase, there was a distinct difference in vocabulary level between Korean textbook and each information leaflet (p < 0.001). CONCLUSION: Patient information leaflets may fail to provide appropriate information for self-determination by clinical trial subject through the difficulty level of its wording. Improvements in the degree of patients' understanding and appropriate use of information leaflets are collaboratively equipped to strengthen patient's autonomy and therefore guaranteeing participant's rights.
Comprehension* ; Disclosure ; Human Rights ; Humans ; Informed Consent ; Prospective Studies ; Research Subjects ; Vocabulary

PURPOSE: The purpose of this study was to analyze the effects of a case management program on range of motion, pain, depression and self efficacy in community-dwelling older women with knee arthritis. METHODS: The research design was one-group pre and post-test design with 40 participants with knee arthritis who agreed to participate in the 12-week case management program. Data were collected four times, before and after 4, 8 and 12 weeks. RESULTS: Repeated measures ANOVA revealed significant differences between before and after the service in range of motion, pain, depression and self efficacy. Significant improvements from the baseline to 4 weeks after the service were observed in the measurements of range of motion, pain, depression and self efficacy. There were no significant differences in range of motion, pain and depression between 4 and 12 weeks after the services. CONCLUSION: This study represents the first effort showing that a case management program can have positive outcomes on range of motion, pain, depression and self efficacy for older women with knee arthritis. More research using a control group pre-post test design considering time lapse is needed in order to examine more accurately the effects of case management programs for knee arthritis.
Arthritis* ; Case Management* ; Depression ; Evaluation Studies as Topic ; Female ; Health Services* ; House Calls* ; Humans ; Knee ; Range of Motion, Articular ; Research Design ; Self Efficacy

No abstract available.
Parenteral Nutrition, Total

No abstract available.
Seroepidemiologic Studies*

Total 9 cases of extraintestinal amoebiasis, amebic liver abscess and amebic lung abscess, were treated with metronidazole. The diagnosis and progress check were done by (1) stool examination, (2) size and pain of liver, (3) hematological examination, (4) urinanalysis, (5) X-ray or liver scanning (6) examination of aspirated pus from liver and (7) immobilization test of E. histolytica. Results are summarized as follows: Amebic hepatitis: Metronidazole was given to 3 cases with daily dose of 0.9-1.2 gm for 3-7 days. Clinical symptoms were completely restored by the treatment. Amebic lung abscess: One case was treated with metronidazole for 3 days with the daily dose 1.2 gm. X-ray findings showed remarkable improvement by the treatment. An additional administration of the drug for 6 days resulted complete resolution of the pneumonic changes. Amebic liver abscess: Four cases were treated with metronidazole. The daily doses were 0.4-2.4 gm and continued for 2-10 days. Aspiration of the abscess for 1-10 times or continuous drainage of pus were performed during the course supplementarily. All cases were recovered to normal by the combining treatment. No remarkable side effect was noticed by the drug administration, and no relapse was experienced up to date.
parasitology-protozoa-Entamoeba histolytica ; chemotherapy ; metronidazole ; liver ; lung ; amoebiasis