1.Feasibility of utilizing the patellar ligament angle for assessing cranial cruciate ligament rupture in dogs.
Journal of Veterinary Science 2014;15(4):563-568
The patellar ligament angle (PLA) was assessed in 105 normal stifle joints of 79 dogs and 33 stifle joints of 26 dogs with a ruptured cranial cruciate ligament (CrCL). The PLA of stifles with complete CrCL rupture was significantly lower than that of normal stifles, particularly at a flexion angle of 60~80degrees in both plain and stress views. If the PLA was <90.55degrees on the stress view with a 60~80degrees flexion angle, the dog was diagnosed with a complete rupture of the CrCL with a sensitivity of 83.9% and specificity of 100%. In conclusion, measuring the PLA is a quantitative method for diagnosing complete CrCL rupture in canines.
Animals
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Anterior Cruciate Ligament/*injuries/radiography
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Dogs/*injuries
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Patellar Ligament/physiology/*radiography
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Radiography/*veterinary
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Retrospective Studies
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Rupture/veterinary
2.Idiopathic type-4 hiatal hernia in a middle-aged cat
Gi Na KIM ; Soon Wuk JEONG ; Hun Young YOON ; Hyun Jung HAN
Korean Journal of Veterinary Research 2018;58(2):111-114
A 6-year-old female domestic short hair cat presented with acute onset of vomiting, anorexia, lethargy, and tachypnea. The cat was apparently healthy prior to presentation without history of trauma. On diagnostic imagings, the entire stomach and spleen were detected in the thoracic cavity. An emergent celiotomy was performed, and a type-4 hiatal hernia was confirmed; the stomach, spleen, pancreas, and duodenum were herniated through the esophageal hiatus. It was corrected using phrenicoplasty, esophagopexy, and left-sided gastropexy and there was no recurrence 16 months after surgery. This is the first case report of an idiopathic type-4 hiatal hernia in a cat.
Animals
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Anorexia
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Cats
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Child
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Duodenum
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Female
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Gastropexy
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Hair
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Hernia, Hiatal
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Humans
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Lethargy
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Pancreas
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Recurrence
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Spleen
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Stomach
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Tachypnea
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Thoracic Cavity
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Vomiting
3.Idiopathic type-4 hiatal hernia in a middle-aged cat
Gi Na KIM ; Soon Wuk JEONG ; Hun Young YOON ; Hyun Jung HAN
Korean Journal of Veterinary Research 2018;58(2):111-114
A 6-year-old female domestic short hair cat presented with acute onset of vomiting, anorexia, lethargy, and tachypnea. The cat was apparently healthy prior to presentation without history of trauma. On diagnostic imagings, the entire stomach and spleen were detected in the thoracic cavity. An emergent celiotomy was performed, and a type-4 hiatal hernia was confirmed; the stomach, spleen, pancreas, and duodenum were herniated through the esophageal hiatus. It was corrected using phrenicoplasty, esophagopexy, and left-sided gastropexy and there was no recurrence 16 months after surgery. This is the first case report of an idiopathic type-4 hiatal hernia in a cat.
4.Cutaneous hemangiopericytoma in a dog : Cytologic and Histopathologic findings.
Tae Woo KIM ; Min Hee KANG ; Soon Wuk JUNG ; Hee Myung PARK
Journal of Biomedical Research 2013;14(1):51-54
A 10-year-old, castrated male, English cocker spaniel dog was presented for evaluation of a mass in the left forelimb. Physical examination revealed a solitary subcutaneous mass measuring 2.7 x 2.1 x 1 cm in size. Radiographs and ultrasonography showed a well-circumscribed, focally mineralized, non-invasive to muscle layer mass without signs of further bone invasion and periosteal reaction. Cytologic evaluation of the mass through fine needle aspiration revealed a mesenchymal cell type malignant tumor without distant metastasis. An excisional biopsy was performed for definitive diagnosis and the mass was diagnosed as cutaneous hemangiopericytoma. This case report presents disagreement between fine needle aspiration and histopathology during diagnostic procedures of cutaneous hemangiopericytoma in a dog.
Animals
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Biopsy
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Biopsy, Fine-Needle
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Dogs
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Forelimb
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Hemangiopericytoma
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Humans
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Male
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Muscles
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Neoplasm Metastasis
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Physical Examination
5.Surgical removal of stones in the stomach of a tiger shovelnose catfish.
Hun Young YOON ; Soon Wuk JEONG ; Young Min CHOI ; Man bok JEONG ; Joon Young KIM ; Hyun Jung HAN ; Min HWANG ; Byung Kuk NO ; Sang Hyuk PARK
Journal of Veterinary Science 2004;5(3):275-277
A seven months old, tiger shovelnose catfish was referred to the veterinary medical teaching hospital of the college of veterinary medicine, Konkuk university because of suspecting a foreign body in the stomach. By physical and radiologic examinations, the catfish revealed abdominal enlargement, vomiting, inactivity and radiopaque foreign bodies in the stomach. Under general anesthesia with dilute isoflurane solution, celiotomy was performed. Stomach was atonic, and three foreign bodies were palpated in the stomach. In this process, three stones came out through mouth. Abdominal muscles were closed with a simple continuous suture pattern, and skin was closed with a simple mattress suture pattern. Sutured site was covered with glue and mucous taken from allogenic skin. On the second day after surgery, the patient recovered to normal condition, showing increased appetite and activity.
Animals
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Catfishes/*surgery
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Foreign Bodies/pathology/*surgery
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Gastroscopy/veterinary
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Stomach/*surgery
6.The Safety and efficacy of a new self-expandable intratracheal nitinol stent for the tracheal collapse in dogs.
Joon young KIM ; Hyun jung HAN ; Hun young YUN ; Bora LEE ; Ha young JANG ; Ki dong EOM ; Hee myung PARK ; Soon wuk JEONG
Journal of Veterinary Science 2008;9(1):91-93
To evaluate the potential utility of a self-expandable intratracheal nitinol stent with flared ends for the treatment of tracheal collapse in dogs, endotracheal stenting therapy was performed under fluoroscopic guidance in four dogs with severe tracheal collapse. During the 4 to 7 month followup, after stent implantation, clinical signs, including dyspnea and respiratory distress, dramatically improved in all dogs. The radiographs showed that the implanted stents improved the tracheal collapse, and there were no side effects such as collapse, shortening or migration of the stents. In conclusion, the self-expandable intratracheal nitinol stents provided adequate stability to the trachea and were effective for attenuating the clinical signs associated with severe tracheal collapse.
*Alloys
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Animals
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Dog Diseases/*surgery
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Dogs
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Female
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Male
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Prosthesis Implantation/adverse effects/veterinary
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Stents/adverse effects/*veterinary
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Tracheal Stenosis/surgery/*veterinary
7.Real-world effectiveness of a single conventional diseasemodifying anti-rheumatic drug (cDMARD) plus an anti-TNF agent versus multiple cDMARDs in rheumatoid arthritis: a prospective observational study
Min Wook SO ; Sang-Hyon KIM ; Dong Wook KIM ; Yoon-Kyoung SUNG ; Jung-Yoon CHOE ; Sang-Il LEE ; Jin-Wuk HUR ; Hye-Soon LEE ; Sang-Heon LEE ; Jin Ran KIM
Journal of Rheumatic Diseases 2024;31(2):86-96
Objective:
The objective of this prospective, observational multicenter study (NCT03264703) was to compare the effectiveness of single conventional disease-modifying anti-rheumatic drug (cDMARD) plus anti-tumor necrosis factor (TNF) therapy versus multiple cDMARD treatments in patients with moderate-to-severe rheumatoid arthritis (RA) following cDMARD failure in the real-world setting in South Korea.
Methods:
At the treating physicians’ discretion, patients received single cDMARD plus anti-TNF therapy or multiple cDMARDs. Changes from baseline in disease activity score 28-joint count with erythrocyte sedimentation rate (DAS28-ESR), corticosteroid use, and Korean Health Assessment Questionnaire (KHAQ-20) scores were evaluated at 3, 6, and 12 months.
Results:
Of 207 enrollees, the final analysis included 45 of 73 cDMARD plus anti-TNF and 91 of 134 multiple-cDMARD recipients. There were no significant between-group differences (BGDs) in ANCOVA-adjusted changes from baseline in DAS28-ESR at 3, 6 (primary endpoint), and 12 months (BGDs −0.18, −0.38, and −0.03, respectively). More cDMARD plus anti-TNF than multiple-cDMARD recipients achieved a >50% reduction from baseline in corticosteroid dosage at 12 months (35.7% vs 14.6%; p=0.007). Changes from baseline in KHAQ-20 scores at 3, 6, and 12 months were significantly better with cDMARD plus antiTNF therapy than with multiple cDMARDs (BGD −0.18, −0.19, and −0.19 points, respectively; all p≤0.024).
Conclusion
In the real-world setting, relative to multiple cDMARDs, single cDMARD plus anti-TNF therapy significantly improved quality-of-life scores and reduced corticosteroid use, with no significant BGD in disease activity, in RA patients in whom previous cDMARD therapy had failed.
8.Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity
Kichul SHIN ; Sung Soo KIM ; Sang-Heon LEE ; Seung-Jae HONG ; Sung Jae CHOI ; Jung-Yoon CHOE ; Seung-Geun LEE ; Hoon-Suk CHA ; Eun Young LEE ; Sung-Hwan PARK ; Jin-Wuk HUR ; Sung Soo NA ; Chang-Hee SUH ; Min Wook SO ; Seung Won CHOI ; Dong-Hyuk SHEEN ; Won PARK ; Shin-Seok LEE ; Wan Hee RYU ; Jin Seok KIM ; Jung Soo SONG ; Hye Soon LEE ; Seong Ho KIM ; Dae-Hyun YOO
The Korean Journal of Internal Medicine 2020;35(1):231-239
The objective of this study was to compare changes in the simplified disease activity index (SDAI) between biologic (b) and conventional (c) disease-modifying antirheumatic drugs (DMARD) users with seropositive rheumatoid arthritis (RA) in daily clinical practice. Methods: This was a nationwide multicenter observational study. Patients who had three or more active joint counts and abnormal inf lammatory marker in blood test were enrolled. The selection of DMARDs was determined by the attending rheumatologist. Clinical parameters, laboratory findings, and Health Assessment Questionnaire (HAQ) scores were obtained at baseline and at 6 and 12 months. Serial SDAI changes and clinical remission rate at 6 and 12 months were assessed. Results: A total of 850 patients participated in this study. The mean baseline SDAI score in bDMARD group was higher than that in cDMARD group (32.08 ± 12.98 vs 25.69 ± 10.97, p < 0.0001). Mean change of SDAI at 12 months was –19.0 in the bDMARD group and –12.6 in the cDMARD group (p < 0.0001). Clinical remission rates at 12 months in bDMARD and cDMARD groups were 15.4% and 14.6%, respectively. Patient global assessment and HAQ at 12 months were also significantly improved in both groups. Multivariate logistic regression showed that baseline HAQ score was the most notable factor associated with remission. Conclusions: There was a significant reduction in SDAI within 12 months after receiving DMARDs in Korean seropositive RA patients irrespective of bDMARD or cDMARD use in real-world practice. Clinical remission was achieved in those with lower baseline HAQ scores.