A case of 39-year-old male with keratosis palmoplantaria nummularis was reported. The skin lesions were characterized by the presence of painful focal keratoses on the plantar pressure points. Biopsy of a keratotic plantar lesion revealed excessive hyperkerstosis, hypergranulosis, focal hypogranulosis, and acanthosis in the epidermis. We could observe aymptomatic relief of this patient who was treated with mixture of corticosteroid, 25% urea and 2.5% salicylic acid.
Adult ; Biopsy ; Epidermis ; Humans ; Keratosis* ; Male ; Salicylic Acid ; Skin ; Urea

PURPOSE: This study identifies the relation among the essentials of fundamental nursing skills performance (EFNSP), work capability and stress from work experienced by new clinical nurses. METHOD: This is a cross-sectional descriptive study with a self-reported questionnaire. The subjects were 224 new clinical nurses employed by general hospitals having more than 400 beds. The data, collected from February 10 to March 7, 2014, were analyzed using descriptive statistics, t-tests, ANCOVA, Pearson's correlation analysis and hierarchical linear regression. RESULTS: The highest frequency of EFNSP of new clinical nurses was vital sign measurement (4.74, +/-.89) and the lowest frequency of performance was Basic CPR & defibrillator application (1.81, +/-.94). There were significant positive correlations between frequency and confidence of EFNSP (r=.64, p<.001), frequency and work capability (r=.34, p<.001), and confidence of EFNSP and work capability (r=.48, p<.001), but negative correlation stress from work and work capability (r=-.17, p=.009). General characteristics, stress from work, frequency and confidence in EFNSP and stress from work explain 25.1% of work capability. CONCLUSION: This result suggests the importance of EFNSP education in nursing schools and availability of opportunities to practice EFNSP during the post-graduation waiting period until assignment to a hospital.
Cardiopulmonary Resuscitation ; Defibrillators ; Education ; Hospitals, General ; Linear Models ; Nursing* ; Surveys and Questionnaires ; Schools, Nursing ; Vital Signs

In this study the effect of insulin and aminoguanidine on the expression of iNOS and the development of insulitis in the multiple low dose streptozotocin (SZ) induced diabetic (LDSD) mice was evaluated. Eighty mice (Charles-River CD-1 mice) were divided into four groups. Group I received SZ for five days. Group II received SZ for five days and was followed by insulin treatment. Group III received SZ for five days and was followed by aminoguanidine treatment. Group IV was normal control group. The blood glucose level and body weight were measured weekly. On the 35th day, pancreat ic sections were observed to evaluate the frequency and the severity of insulitis in addition to the immunohistochemical expression of iNOS in the pancreatic islets. Blood glucose levels of group IV were significantly lower than other experimental groups on the 21st, 28th, and 35th day. The difference in blood glucose levels was not statistically significant. Incidence of the insulitis was lower in group II than in groups I and III. The severity of insulitis correlated with the increase in blood glucose level only in group II. The expression of iNOS was more pronounced in group I than in groups II and III. Aminoguanidine did not inhibit development of the insulitis but decreased expression of iNOS in the pancreatic islets. Therefore it is speculated that iNOS production is one of the factors and other pathogenetic mechanisms might be involved in the development of insulitis.
Animals ; Blood Glucose ; Body Weight ; Incidence ; Insulin* ; Islets of Langerhans ; Mice* ; Nitric Oxide Synthase Type II* ; Streptozocin

This study was undertaken to investigate the immunological mechanism of Behqet s syndrome, considered to be important in the pathogenesis of the disease. Seventy- three patients with complete, incomplete and suspected types of Behget's syndrotne were tested for leukocyte migration ingibition factor(LIF), one of the lymphokines. The results were as follows : 1. There was no difference between the average LIF activity of all the patients and that of eontrol. 2. LIF activity of complete type, according to Shirnizus classification, was significaritly lower than the control value. 3. LIF activity of ocular type, according to Lehners classification, was signficantly lower than the control value. 4. LIF activity for patients with 4 clinical symptoms was well below the value for patients with less symptomes 5. For patients with single clinical symptom, LIF activity of complete type was well below the values of incomplete and suspected types. 6. In suspected and mucocutaneous types, LIF activity was low when the patients showed two clinical symptoms than one. Thus, LIF activity was low for patients with complete, ocular and neurological types and with multiple symptorns.
Behcet Syndrome* ; Classification ; Humans ; Leukocytes* ; Lymphokines

Ischiofemoral impingement (IFI) syndrome is an uncommon cause of gluteal and hip pain. We report on a case of a 20-year-old man who presented with chronic gluteal and hip pain with low back pain without a history of trauma or surgery. He was misdiagnosed with ankylosing spondylitis (AS) at another clinic. The patient was finally diagnosed with IFI syndrome according to pelvic magnetic resonance imaging findings at our hospital. After two weeks of medical and physical treatment, his pain showed gradual improvement. Because IFI syndrome is rarely reported in male patients, it might be misdiagnosed as AS. Therefore, IFI syndrome should be considered as a differential diagnosis of AS, particularly in young male patients with atypical pain characteristics.
Diagnosis, Differential* ; Hip ; Humans ; Low Back Pain ; Magnetic Resonance Imaging ; Male ; Spondylitis, Ankylosing* ; Young Adult

No abstract available.
Granuloma, Plasma Cell*

Behcet's syndrome is being detected increasingly in Korea. To collect and document information concern- ing the clinical picture as it is records of patients seen in our clinic in the period between November 1983 and March 1986 were used as source material. In summary, it was found that (1) the total number of patients who had two majors symptoms at least were 410, including 170 men and 240 women; (2) Patients in their thirties were the most common, the mean age being 34.6 years; (3) according to Lehner's classification, the order of frequency of the different types was mucocutaneous (52%), ocular (33), arthritic (14%) and neurologic (1%) and according to Shimizu's classification, it was incomplete (39%), suspected (37%), and complete (24%); (4) oral ulcers, which had observed in 407 patients were the most frequent major symptom, followed by genital ulcers in 338 patients.
Adolescent ; Adult ; Age Factors ; Aged ; Behcet Syndrome/classification/diagnosis/*epidemiology ; Child ; Epidemiologic Methods ; Female ; Human ; Korea ; Male ; Middle Age ; Seasons ; Sex Factors

BACKGROUND: Insufficient supply of donated kidneys for the demand of patients willing to transplant kidney, has been predisposed as main limitation to renal transplantation in Korea. Recently, a lot of Korean patients with end stage renal disease have visited China for cadeveric renal transplantation from executed prisoners. Here, we report a clinical investigation about 19 patients of our hospital, who have received kidney transplant in China. METHODS: We selected 19 patients who had received renal transplantation in China from January, 1st, 2003 to september, 30th, 2004. We interviewed them and reviewed their hospital records and laboratory datas. RESULTS: Their mean age was 47.7+/-11.7 (27-66) years, and male to female patients ratio was 13 vs 6. All of them did not have received renal transplantation before and 15 of them had no living related donor in their own family. All of them had been treated with dialysis therapy, and patients with hemodialysis versus patients peritoneal dialysis were 14 vs 5. Their mean dialysis duration was 26.8+/-23.7 (1-90) months. Among the causes of end stage renal disease of them, hypertension was most common and next was chronic glomerulonephritis, and Diabetes mellitus was 3rd place. All of them received kidneys from cadeveric donors as executed prisoners, and mean duration of their Chinese hospital residence was 15.9+/-7.2 (10-32) days. Post-transplantation follow-up duration of them was 12.3+/-4.1 (4-19) months. During the period above, the number of post-transplantation complication was six, and 2 of 19 patients were expired of intra-cranial hemorrhage and Aspergillos infection, each. CONCLUSION: We offer important problems caused by increasing numbers of renal transplantation in China, and suggest more serious discussions and countermeasures among relevant authorities.
Asian Continental Ancestry Group ; China* ; Diabetes Mellitus ; Dialysis ; Female ; Follow-Up Studies ; Glomerulonephritis ; Hemorrhage ; Hospital Records ; Humans ; Hypertension ; Kidney ; Kidney Failure, Chronic ; Kidney Transplantation ; Korea* ; Male ; Peritoneal Dialysis ; Prisoners ; Prisons ; Renal Dialysis ; Tissue Donors ; Transplantation*

No abstract available.
Female ; Hysterectomy* ; Hysterectomy, Vaginal*

BACKGROUND/AIMS: To evaluate the therapeutic efficacy of interferon in chrcnic viral hepatitis, interferon was administered to 222 patients with biopsy proven chronic viral hepatitis. METHODS: 32 patients were excluded and the 190 patients was included, 149 men and 41 women. Average age was 34.4+-8.93 (14-67) years. 161 cases had HBsAg and HBeAg, and 29 cases had anti-HCV Ab. Three millicn units of interferon beta were given to 37 patients with chronic B hepatitis, daily for one month Six million units of interferon alpha were given to 124 patients with chronic B hepatitis and 29 patients with chr onic C hepatitis, three times a week for six months. RESULTS: 1) Out of 124 patients with clronic hepatitis B treated with a-interferon, HBeAg negativity for more tban six months was observed in 25 patients (20.2%), and defined as responder group. The 23 patients (18.5%) were defined as probable responder, because of persistent seroregativity of HBeAg for the last 6 months, despite of fluctuation of sercangativity during the follow-up. The 29 patients (23.4%) were defined as probable non-responder because of recurrence of HBeAg, which once was cleared but reappeared during last 6 months. But there was no seroconversion in 47 cases (37.9%). The overall response rate was 38.7%. 2) Out of 37 patients with chronic hepatitis B treated with B-interferon, 7 patients (18.9%) were responder, 6 patients (16.2%) probable responder, 12 patients (32.4%) probable non-responder, 12 patients (32.4%) non-responder. The overall response rate was 35.1%. 3) Out of 29 patients with chronic hepatitis C treated with a-interferon, normalization of alanine aminotransferase (ALT) level for mcrre than six months was observed in 9 patients (31.0%), and defined as responder group. The 3 patients (10.3%) were defined as probable responder, because ALT levels fluctuated but wes normalized during the last 6 months. The 5 patients (17.2%) were defined as pobable ncn-mponder, because of persistent fluctuation of ALT levels during the last 6manths, which once were normalized but reelevated. In 12 patients (41.4%), there had never been a normalization of ALT level. The overall resporate was 41.1%. 4) The period of HBeAg seropositivity was 1.33 times longer than the period of seronegativity. The faster the seroconvmion, the more the tendency to be a respander for the patients with chronic hepatitis B. CONCLUSION: Interferon therapy may be effective in some cleonic viral hepatitis.
Alanine Transaminase ; Biopsy ; Female ; Follow-Up Studies* ; Hepatitis B ; Hepatitis B e Antigens ; Hepatitis B Surface Antigens ; Hepatitis B, Chronic ; Hepatitis C, Chronic ; Hepatitis* ; Humans ; Interferon-alpha ; Interferon-beta ; Interferons* ; Male ; Recurrence