1.A Case of Torsion of Wandering Spleen.
Soon Kyung BAIK ; Seung Kyu PARK ; Seung Ok PARK ; Soon Jeong LEE ; Dong Jin LEE
Journal of the Korean Pediatric Society 1994;37(12):1773-1777
The wandering spleen is a rare condition, in which the spleen is located in other than the left upper quadrant of the abdomen. The clinical manifestation is variable from asymptomatic to abdominal catastrophy due to torsion of the splenic pedicle. We experienced a case of torsion of wandering spleen in 8-year-old girl who admitted with fever, vomiting, abdominal pain, palpable left abdominal mass. She was diagnosed preoperatively with the aid of abdominal sonography and C.T. scanning. A splenectomy was performed and she made uneventful recovery. The case report illustrates some of the diagnostic and therapeutic considerations pertaining to wandering spleen with a brief review of related literature.
Abdomen
;
Abdominal Pain
;
Child
;
Female
;
Fever
;
Humans
;
Spleen
;
Splenectomy
;
Vomiting
;
Wandering Spleen*
2.Clinical Observation of Neonatal Sepsis according to Onset of Disease.
Young Chul JANG ; Soon Kyung BAIK ; Chang Sung LIM ; Dong Jin LEE
Journal of the Korean Pediatric Society 1994;37(12):1676-1686
We have experienced 113 cases of neonatal sepsis comfirmed by clinical manifestations and blood cultures from Jan. 1988 to Dec. 1992 at the Neonatal Intensive Care Unit of Ulsan Dong-Kang Hospital and observed the incidence, predisposing perinatal factors, clinical manifestations, associated illnesses, laboratory findings, isolated microorganisms, antibiotics sensitivity test and mortality rate of neonatal sepsis according to onset of disease. The result were as follows: 1) The incidence of neonatal sepsis was 1.39% and male to female ration was 1.38:1. The incidence and sex difference between early onset and late onset disease were not significant. 2) Neonatal sepsis was more prevalent in premature infants (2.47%) than in fullterm infants (1.28%) and nore prevalent in low birth weight infants(3.01%) than in normal birth weight infants (1.25%). In premature infants, neonatal sepsis was more prevalent in early onset (63.2%) than in late onset diease (36.8%). In low birth weight infants, neonatal sepsis was more prevalent in early onset (64.8%) than in late onset dieases (35.7%P). 3) Predisposing perinatal factors, such as meconium staining, birth asphyxia, difficult delivery, premature rupture of membrane, maternal infection, toxemia and postpartum bleeding were slightly frequent in early onset disease. 4) Among the clinical manifestations, jaundice, respiratory symptoms, pallor, lethargy, poor feeding and hepatosplenonegaly were slightly frequent in early onset disease, but temperature instability and gastrointestinal symptoms were slightly frequent in late onset disease. 5) Among the associated illness, pneumonia, disseminated intravascular coagulopathy, amnionitis, hyaline membrane disease and osteomyelits were more common in early onset disease, but gastroenteritis, urinary tract infection, necrotizing enterocolitis, wound infection and meningitis were mors common in late onset disease. 6) The difference of laboratory findings between early onset and late onset disease was not significant. 7) Causative organisms were gram positive organisms in 87 cases(77.0%), gram negative organisms in 22 cases (18.6%) and mixed infections in 5 cases (4.4%). Among them, coagulase negative staphylococcus was the most common one and staphylococcus aureus was the second. The incidence of infections caused by coagulase negative staphylococcus and staphylococcus aureus, between early onset and late onset disease, was not significantly different. Streptococcal infection was more prevalent in early onset disease, especially all group B streptococcus caused early onset disease. 8) Gram positive organisms ware sensitive to Cephalothin (92.9%), Chloramphenicol (90.0%) and Ceftriaxone (88.9%). Gram negative organisms were sensitive to Amikacin (91.3%) and Colistin (82.6%). The difference of antibiotics sensitivity for organisms causing early onset and late onset diease were not significant. Gram negative organisms causing early onset disease were resistant to gentamicin and terramycin, but those organisms causing late onset disease were more sensitive to gentamicin (88.9%) and tobramycin (77.8%). 9) The mortality rate was 7.96%. It was higher in gram negative infections (23.8%) than in gram positive infections (4.6%). No significant difference of mortality rate between early onset and late onset disease was found.
Amikacin
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Amnion
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Anti-Bacterial Agents
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Asphyxia
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Birth Weight
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Ceftriaxone
;
Cephalothin
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Chloramphenicol
;
Chorioamnionitis
;
Coagulase
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Coinfection
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Colistin
;
Enterocolitis, Necrotizing
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Female
;
Gastroenteritis
;
Gentamicins
;
Hemorrhage
;
Humans
;
Hyaline Membrane Disease
;
Incidence
;
Infant
;
Infant, Low Birth Weight
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Infant, Newborn
;
Infant, Premature
;
Intensive Care, Neonatal
;
Jaundice
;
Lethargy
;
Male
;
Meconium
;
Membranes
;
Meningitis
;
Mortality
;
Oxytetracycline
;
Pallor
;
Parturition
;
Pneumonia
;
Postpartum Period
;
Pregnancy
;
Rupture
;
Sepsis*
;
Sex Characteristics
;
Staphylococcus
;
Staphylococcus aureus
;
Streptococcal Infections
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Streptococcus
;
Tobramycin
;
Toxemia
;
Ulsan
;
Urinary Tract Infections
;
Wound Infection
3.Effects of methylene blue or evan's blue on mouse embryo development, human sperm motility, serum E2 level and components of human intra tubal fluid.
Chun Soon BAIK ; Byung Hee SUH ; Jae Hyun LEE ; Kyung Kwang LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):1133-1138
No abstract available.
Animals
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Embryonic Development*
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Embryonic Structures*
;
Evans Blue*
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Female
;
Humans*
;
Methylene Blue*
;
Mice*
;
Pregnancy
;
Sperm Motility*
;
Spermatozoa*
4.Two Cases of Takayasu's Aortitis Causing Acute Myocardial Infarction.
Soon Koo BAIK ; Keum Soo PARK ; Seung Hwan LEE ; Kyung Hoon CHOE ; Sung Oh HWANG
Korean Circulation Journal 1992;22(2):322-329
The myocardial infarction is usually associated with the coronary artery disease in adults. It is unusual in chilhood and young adult but occasionally associated with coronary vasculitis. Takayasu's arteritis produces a panaortits with thickening of the adventitia and narrowing of aorta. Narrowing of coronary arteries is due to extension into these arteries of the processes of inflammation that occur in aorta. We report here two cases of Takayasu's aortitis causing acute myocardial infarction. Case 1 is a 17-year-old girl presented with the inferior myocardial infarction and the cerebral infarction. Digital subtraction aortography showed a diffuse narrowing of the aorta and the obstruction of both subclavian arteritis, right carotid artery and both femoral arteries. Case 2 is a 19-year-old male patient with anterior myocardial infarction. Coronary cineangiogram showed the beak like appearance of the left main coronay artery.
Adolescent
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Adult
;
Adventitia
;
Animals
;
Aorta
;
Aortitis*
;
Aortography
;
Arteries
;
Arteritis
;
Beak
;
Carotid Arteries
;
Cerebral Infarction
;
Coronary Artery Disease
;
Coronary Vessels
;
Female
;
Femoral Artery
;
Humans
;
Inferior Wall Myocardial Infarction
;
Inflammation
;
Male
;
Myocardial Infarction*
;
Takayasu Arteritis
;
Vasculitis
;
Young Adult
5.Observation on the platelet activation in disseminated intravascular coagulation.
Kyung Soon SONG ; Seung Bok LEE ; Baik Soo KIM ; Oh Hun KWON ; Samuel Y LEE
Korean Journal of Hematology 1991;26(1):81-85
No abstract available.
Blood Platelets*
;
Disseminated Intravascular Coagulation*
;
Platelet Activation*
6.An analysis of HPV subtype in the uterine cervix and clinical usefulness of HPV DNA chip test.
Soon Ho CHOI ; Kyung Don BAIK ; Su Il LEE
Korean Journal of Obstetrics and Gynecology 2007;50(3):465-475
OBJECTIVE: Human papillomavirus (HPV) has been identified more than 100 HPV subtypes. The distributions of subtypes are different according to nations and regions. We analysed subtype of infection with HPV among women who live in Pusan and surburbs of Pusan. We accessed the clinical usefulness of HPV DNA chip test as a supplementary method of Pap smear in the evaluation of cervical lesion. METHOD: This study was undertaken from January 2002 to January 2005 and the samples were collected from the patients who had abnormal Pap smear. We analysed subtypes of 143 positive cases with HPV DNA chip (Biomedlab) test and estimated pathologic reports of 115 patients except 28 patients who had not biopsy. We investigated pathologic results of 54 of 115 patients who had atypical squamous cells / low grade squamous intraepithelial lesion (ASC/LSIL) in Pap smear and examined high risk HPV in 54 pathologic results. RESULTS: The prevalence of HPV subtypes was 42 cases of HPV-16, 20 cases of HPV- 58, 16 cases of HPV-52, 10 cases of HPV-35, 9 cases of HPV-56, 7 cases of HPV-51, 6 cases of HPV-18 in descending order of incidence in high risk HPV group and 3 cases of HPV-6, 3 cases of HPV-42, 2 cases of HPV-34, 2 cases of HPV-43 in descending order of incidence in low risk HPV group. The results of HPV DNA chip test and 115 pathologic reports were estimated by comparative study. A pure infection with low risk HPV group was detected in low grade lesion. Infection with high risk HPV group was also detected in low grade lesion but was mainly detected in high grade lesion. The pathologic results of 54 patients who had ASC / LSIL in Pap smear were 13 patients had above high grade lesion include 2 cases of invasive carcinoma so false negative rate of Pap smear in the detection of high grade lesion was 24%. CONCLUSION: HPV subtypes were detected HPV 16, 58, 52, 35, 56, 51, 18 types in descending order of incidence and prevalence. Mass study and integrated data from larger population and various regions in many hospitals will be needed. And the supplementary use of HPV DNA chip test may provide clinical usefulness because it can reduce the false negative rate of Pap smear and improve the positive predictive value in the detection of high grade cervical lesion and it enables to decrease the incidence of cervical cancer.
Biopsy
;
Busan
;
Cervix Uteri*
;
DNA*
;
Female
;
Human papillomavirus 16
;
Human papillomavirus 18
;
Human papillomavirus 6
;
Humans
;
Incidence
;
Oligonucleotide Array Sequence Analysis*
;
Prevalence
;
Uterine Cervical Neoplasms
7.A Case of Partial Trisomy 9 by Balanced Maternal Translocation .
Mi Kyung KIM ; Young Kyoo SHIN ; Baik Lin EUN ; Sang Hee PARK ; Sun Hwa PARK ; Soon Hyuk LEE
Journal of the Korean Pediatric Society 2000;43(5):700-703
Trisomy 9p syndrome was first described by Rethore et al in 1970 and about 100 cases have been reported since. The phenotypic spectrum of this syndrome is characterized by craniofacial malformation, facial deformity, skeletal and dermatoglyphic anomalies with variable degrees of mental retardation. We experienced a case of partial trisomy 9 syndrome in a 15-month-old female who had multiple congenital anomalies of frontal bossing, oblique antimongoloid palpebral fissures, enophthalmos, hypertelorism, globular prominent nose, down-turned mouth, prominent low-set ears, simian creases of both hands, clinodactyly and single crease of 5th finger, congenital dislocation of both knees and mental retardation. In cytogenetic studies using G banding technique and fluorescent in situ hybridization(FISH), she presented with an extra derivative chromosome No. 9. The karyotype of the patient was confirmed as 47,XX,+der (9),t (6:9) (q27;q21.2) mat. We report the case with the review of the associated literatures.
Congenital Abnormalities
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Cytogenetics
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Dermatoglyphics
;
Dislocations
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Ear
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Enophthalmos
;
Female
;
Fingers
;
Hand
;
Humans
;
Hypertelorism
;
Infant
;
Intellectual Disability
;
Karyotype
;
Knee
;
Mouth
;
Nose
;
Trisomy*
8.Histopathologic Correlation of Magnetic Resonance Image Findings in Ischemic Necrosis of the Femoral Head (INFH)
Choong Hee WON ; Sueng Baik KANG ; Bong Soon CHANG ; Geon SHIN ; Kyung Chul JEON ; Jin Sun YOO
The Journal of the Korean Orthopaedic Association 1996;31(3):499-505
Magnetic resonance image of INFH were correlated with histologic sections. Seventeen patients withe eighteen hips were included in this study. reoperative radiographs and MRI were taken for the patients. Three hips were in stage II, nine hips were in stage III, and remaining six were in stage IV respectively(Ficat and Alert). These hips were replaced with artificial joint and resected heads were examined. The specimens were bisected along the imaging plane, and studied histologically and matched with respective MR images of T1 and T2. Specimen MRI was performed on three femoral head immediately after femoral head removal. Necrotic portion of the femoral head in earlier stage showed higher signal intensity in T1-weighted image. Subchondral void, necrotic bone and saponified fat were responsible for low signal intensity in necrotic portion. Low signal band adjacent to the necrotic foci represented inner fibrous tissue and outer reactive sclerotic bone. Outside the fibrous band, the signal intensity diminished compared with normal fatty marrow. these findings were attributed by cellular infiltration and trabecular bony proliferation. MRI patterns were variable in various stages, but corresponded well with histologic findings.
Bone Marrow
;
Head
;
Hip
;
Humans
;
Joints
;
Magnetic Resonance Imaging
;
Necrosis
9.Strength of Surgical Wire by Different Wiring Technique
Choong Hee WON ; Sung Soo CHEONG ; Young Do KOH ; Bong Soon CHANG ; Seung Baik KANG ; Kyung Chull JEON
The Journal of the Korean Orthopaedic Association 1996;31(4):909-913
The role of surgical wire in the bone and joint surgery is very important. To get a maximum effect of the surgical wiring, the orthopaedic surgeon should not only select appropriate wire diameter but also apply adequate wiring technique. When strong fixation is required, wire loops are frequently untrustworthy. These are due to insufficient caliber or inadequate technique of wire thightening and/or twisting. The theoretical background for effective wiring technique and useful diameter in cerclage wiring is poor. Ultimate stress and stress at breaking point of different diameter of the wire was higher in 16G than 18G or 21G. Twist knot was stronger than knot twist. Wire holder was more effect than tensioner(york). Tension tightening with twist knot by wire holder have been found most suitable for internal fixation by surgical wire.
Joints