A socio-medical survey was carried out on 1,108 cases of pulmonatory tuberculosis who had registered and 220 cases unregistered at Jeonju Health center in 1973, during from June 1 to July 31, 1974. As the results of this survey, the following conclusions were obtained. 1. Of the total 1,108 cases of pulmonary tuberculosis there were 708 new cases, while remaining 400 were old cases and rate of registration was 4.0 per thousand person. 2. The highest rate of registration of the newly diagnosed pulmonary tuberculosis could be found in bacteriological examination while 54.4 percent in X-ray examination. 3. As for the educational status of the tuberculosis patients, primary school graduates constituted the greatest proportion of 64.6 percent, middle school graduates 13.6 percent. high school graduates 6.8 percent and college graduates only 0.7 percent. 4. By age group of the cases, at age of 20 to 29 years occupied 23.6 percent (262 out of 1,108 cases), 17.9 percent at age of 40 to 49 years. 5. The greatest proportion of 38.4 percent of the cases had no occupation. 6. The living standard of the patient's household, low class constituted 60.6 percent of the total house olds. 7. By distribution of residential area, farming area was 5.0 per thousand person, 4.0 in downtown and suburban areas. 8. The greatest proportion of 70.0 percent of positive cases in X-ray examination was unregistered in August, 63.6 percent in July 1973. 9. 220 out of 1,108 cases(19.9%) were unregistered pulmonary tuberculosis in X-ray and bacteriological examinations. 10. For age groups of unregistered cases, most prevalent age group was 30 to 39. 11. Regarding on the cases of unregistration, 'indifference for disease', 'occupied highest rate with 31.9 percent' and 'private secret' with 15.7 percent. 12. Of the total 457 cases drop-outed, there were 78 complete held cases while remaining 207 inactive.
Educational Status ; Family Characteristics ; Follow-Up Studies* ; Humans ; Jeollabuk-do* ; Occupations ; Socioeconomic Factors ; Tuberculosis* ; Tuberculosis, Pulmonary

Primary hepatic tuberculosis is extremely rare, but liver and spleen involvement secondary to tuberculosis isfrequentand of clinical importance, because of its demonstrability by biopsy. Complete absence of Tc-99m-SulfurColloid uptake of spleen due to splenic tubeculosis has not been reported. We experienced one case of liver andspleen tuberculosis which revealed complete absence of Tc-99m
Biopsy ; Colloids ; Liver ; Spleen ; Tuberculosis ; Tuberculosis, Hepatic

Recently, we found that the Korean traditional medicine could enhance the expression of some cytokine in murine bone marrow cell culture. To understand the mode of actions of the traditional medicine, we examined the pattern of protein phosphorylation in bone marrow cells treated with Korean traditional medicine. When bone marrow cells were treated with Korean traditional medicine, the phosphorylation of p45, p50, p84/p91 kinase was observed, and gene expression of TPO and SCF was related to p45 and p91. It had been reported that TPO, SCF, IL-3 and GM-CSF gene expression transmits signal through the JAK-STAT pathway. Molecular involvement of JAK-STAT in signal induced by Korean traditional medicine was analyzed by anti-JAK and anti-STAT-1 Ab. To analyze the transcriptional factor that promotes the cytokine gene expression by the stirnulation of Korean traditional medicine, GAS and NF-B binding activity was analyzed by EMSA. We found the increase in NF-B at SMT and BHT. Therefore, we conclude that the cytokine gene expression induced by Korean traditional medicine was mediated by the JAK-STAT pathway and by the combination of GAS and NF-kB.
Bone Marrow Cells ; Butylated Hydroxytoluene ; Gene Expression ; Granulocyte-Macrophage Colony-Stimulating Factor ; Hematopoiesis* ; Interleukin-3 ; Medicine, Korean Traditional* ; Medicine, Traditional ; NF-kappa B ; Phosphorylation ; Phosphotransferases ; Signal Transduction

The Korean traditional medicinal (KTM) herbs such as Angelicae gigantis, Rehmannia glutinosa, Paeoniae lactiflora, Cnidii officinale, Salviae miltiorrhizae, and Millettia reticulata, and prescribed formula Samultang, and Bohyultang improve the function of the hematopoietic system and nourishing the body to promote health. However, there are limited scientific background on the mode of action of these medicine. To understand the diverse actions following traditional medicine stimulation, we determined the production of hematopoietic cytokine, thrombopoietin, stem cell factor, and interleukin-3 (IL-3) in KlM treated bone marrow cells. When bone marrow cells were treated with KTM, the expression of hematopoietic cytokine were increased in RT-PCR and ELISA analysis. Furthermore, when the bone marrow cells were separated into adherent celis and suspension cells and were treated with KTM, we found the increase of TPO gene expressions in suspension cells. Meanwhile, other hematopoietic cytokine gene expression in bone marrow cells was higher as whole than when adherent cells and suspension cells was separated. Therefore, we could know the interaction of two cells that increases the cytokine expression. These results suggest that KTM has hematopoietic effects through increasing the production of cytokine.
Angelica ; Bone Marrow Cells ; Enzyme-Linked Immunosorbent Assay ; Gene Expression ; Hematopoiesis* ; Hematopoietic System ; Interleukin-3 ; Medicine, Korean Traditional* ; Medicine, Traditional ; Millettia ; Paeonia ; Rehmannia ; Salvia ; Stem Cell Factor ; Thrombopoietin

No abstract available.
Osteotomy* ; Rabbits*

No abstract available.
Osteotomy* ; Rabbits*

No abstract available.
Korea*

The treatment of frozen shoulder should initially be conservative, with the emphasis on passive stretching of the capsular structures. If the patient's clinical progress stalls or the condition worsens, and his or her life style is disturbed enough, manipulation under gerneral anesthesia is indicated. The Authors practiced the passive manipulation under the general anesthesia on 7 patients of frozen shoulder, who had been treated at the Department of Orthopaedic Surgery, Yonsei University, Wonju College of Medicine, from March 1988 to April 1989. The results obtained were as follows:l. All seven patients achieved nearly full range of motion with minimal or no pain. 2. After 3 months of follow-up, all seven patients showed neither signs of readhesions nor recurrence of pain. 3. There were no complications, such as humerus shaft fracture and dislocation of shoulder.
Anesthesia ; Anesthesia, General ; Bursitis ; Dislocations ; Follow-Up Studies ; Gangwon-do ; Humans ; Humerus ; Life Style ; Muscle Stretching Exercises ; Range of Motion, Articular ; Recurrence ; Shoulder

The echocardiographic results obtained from normal group(910 cases), borderline hypertention group(78 cases), define hypertension group(182 cases) and hypertensive heart disease group(55 cases) in Heart Center, Paik Hospital, Inje Medical College, Pusan, Korea between September 1985, were as followings; 1) LVDeD, 5.94+/-1.07cm in hypertensive heart disease group was significantly increased compared with 4.93+/-0.64cm in normal group, 4.92+/-0.73cm in borderline hypertension group and 4.90+/-0.64cm in define hypertension group. LVSeD, 4.86+/-0.98cm in hypertensive heart disease group was significantly increased compared with 3.24+/-0.58cm in normal group, 3.21+/-0.52cm in definite hypertension group. 2) LVDeV/s, 180.26+/-84.76ml/m2 in hypertensive heart disease group was significantly increased compared with 86.13+/-37.34ml/m2 in normal group, 86.26+/-41.02ml/m2 in borderline hypertension group and 83.78+/-30.86ml/m2 in definite hypertension group, and LVSeV/S, 97.51+/-55.67ml/m2 in hypertensive heart disease group was significantly increased compared with 25.28+/-13.25ml/m2 in normal group, 23.68+/-14.62ml/m2 in borderline hypertension group and 24.02+/-14.36ml/m2 in definite hypertension group. 3) There was no significant differance of SV/S, between 61.50+/-26.02ml/m2 in normal, 63.98+/-30.86ml/m2 in borderline, 63.06+/-22.96ml/m2 in definite hypertension group and 61.82+/-30.67ml/m2 in hypertesive heart disease group. E.F. 44.06+/-9.94% in hypertensive heart disease group was significantly reduced comparing with 71.08+/-8.89% in normal group, while 74.35+/-8.26% in borderline and 73.28+/-8.49% in definite hypertensive was significantly increased. F.S., 17.02+/-5.18% in hypertensive heart disease group was significantly reduced comparing with 34.44+/-6.81% in normal, while 35.64+/-7.62% in borderline and 36.87+/-7.26% in definite hypertension group was significantly increased. 4) VSTh, 1.24+/-0.32cm in hypertensive heart disease group, 1.17+/-0.12cm in definite hypertension group and 1.16+/-0.41cm in borderline hypertension group are significantly increased comparing with 0.99+/-0.21cm in normal group. LVPWTh, 1.01+/-0.27cm in hypertensive heart disease group and 0.90+/-0.21cm in definite hypertension group was significantly increased comparing with 0.79+/-0.16cm in normal group. 5) VSTh was increased in 13.3% of borderline hypertension group, 32.8% of definite hypertension group and 31.6% of hypertensive heart disease group. LVPWTh was increased in 4.4% of borderline hypertensive group, 26.9% of definite hypertension group and 30.2% of hypertensive heart disease group. Symmetrical septal hypertrophy was noted in 5.1% of borderline hypertension group, 20.1% of definite hypertension group and 32.1% of hypertensive heart disease group. Total septal or left ventricular posteior wall hypertrophy was noted in 17(21.8%) of 78 borderline hypertension group, 154(89.8%) of definite hypertension group and 51(93.9%) of 55 hypertensive heart disease group.
Busan ; Echocardiography* ; Heart ; Heart Diseases ; Humans ; Hypertension ; Hypertrophy ; Korea ; Ventricular Function, Left*

No abstract available.
Palate, Hard* ; Salivary Ducts* ; Salivary Glands, Minor*