1.A Study on Status of Birth and Death in an Urban Area.
Yang Won PARK ; Pyong Kap LEE ; Soon Young PARK ; Soon Ja KOH
Korean Journal of Preventive Medicine 1971;4(1):19-30
A survey was conducted by the staff of the Dept. of Preventive Medicine, Kyung Hee University, School of Medicine, from April through May 1971, on such events as delivery, death, abortion and family planning. The survey directed to a total population 6,552 (Male 3,133; Female 3,419) residing in this area (1,262 households) led us to the following findings : 1) Two year averages of crude birth rate, crude death rate and natural increase rates were 24.9, 5.0 and 19.9 respectively. 2) Infant death rates for the years 1969 and 1970 were 13.2 and 5.8 respectively, mean for the two year period being 9.3. 3) Hospital deliveries rated 68.5 percent, Home deliveries 28.4 percent and deliveries at midwives' offices 2.7 percent. 4) Deliveries other than hospital and midwives' office deliveries were found to be attended more often by mothers. 5) About 41.4 percent of all pregnant women during last two years received prenatal care once or more. 6) The induced abortion rate was 6.7 percent in 1969 and 7.5 percent in 1970. 7) The spontaneous abortion rate was 1.1 percent in 1969 and 1.4 percent in 1970. 8) Hypertension was the most frequent cause of adult death(21.6%). 9) The rate of current practice in family planning was 43.3 percent of all women.
Abortion, Induced
;
Abortion, Spontaneous
;
Adult
;
Birth Rate
;
Family Planning Services
;
Female
;
Humans
;
Hypertension
;
Infant
;
Mortality
;
Mothers
;
Parturition*
;
Population Growth
;
Pregnancy
;
Pregnant Women
;
Prenatal Care
;
Preventive Medicine
2.A Study on Status of Birth and Death in an Urban Area.
Yang Won PARK ; Pyong Kap LEE ; Soon Young PARK ; Soon Ja KOH
Korean Journal of Preventive Medicine 1971;4(1):19-30
A survey was conducted by the staff of the Dept. of Preventive Medicine, Kyung Hee University, School of Medicine, from April through May 1971, on such events as delivery, death, abortion and family planning. The survey directed to a total population 6,552 (Male 3,133; Female 3,419) residing in this area (1,262 households) led us to the following findings : 1) Two year averages of crude birth rate, crude death rate and natural increase rates were 24.9, 5.0 and 19.9 respectively. 2) Infant death rates for the years 1969 and 1970 were 13.2 and 5.8 respectively, mean for the two year period being 9.3. 3) Hospital deliveries rated 68.5 percent, Home deliveries 28.4 percent and deliveries at midwives' offices 2.7 percent. 4) Deliveries other than hospital and midwives' office deliveries were found to be attended more often by mothers. 5) About 41.4 percent of all pregnant women during last two years received prenatal care once or more. 6) The induced abortion rate was 6.7 percent in 1969 and 7.5 percent in 1970. 7) The spontaneous abortion rate was 1.1 percent in 1969 and 1.4 percent in 1970. 8) Hypertension was the most frequent cause of adult death(21.6%). 9) The rate of current practice in family planning was 43.3 percent of all women.
Abortion, Induced
;
Abortion, Spontaneous
;
Adult
;
Birth Rate
;
Family Planning Services
;
Female
;
Humans
;
Hypertension
;
Infant
;
Mortality
;
Mothers
;
Parturition*
;
Population Growth
;
Pregnancy
;
Pregnant Women
;
Prenatal Care
;
Preventive Medicine
3.A Study on the Academic Paper Review Process of Medical Societies.
Myung Ja KOH ; Soon Duck KIM ; Young Sung LEE ; Byung Chul CHUN
Journal of Korean Society of Medical Informatics 2003;9(2):199-205
The subjects in this study were the directors in charge of article inspection from 127 academies that are registered with the Korea Academy of Medical Science. After a questionnaire was prepared covering the examination process, judging committee organization, problems with examination and possible reform measures, a survey was conducted by e-mail and facsimile from October 4 through 20, 2001. The responses from 79 academies were gathered, a response rate of 62.2%, and the collected data were analyzed with SAS. The most common examination process was C type, which convenes publishing committees, employed by 59 academies_(74.6%), and these institutes found it satisfactory. Thirty-four academies_(43.0%) had 10 to 19 judges, and these judges were separately in charge of different fields, whereas 79 academies_(77.3%) allocated five or less judges to each field. Thirty_(38.0%) academies had their judges comply with related official directions or guidelines, and 50 academies_(63.3%) conducted investigation just twice. Fifty-four academies_(68.4%) weren't satisfied with their examination process. As for the problems with the examination process, many_(41.8%) pointed out that it's time-consuming work and that a lot of procedures were repeated. Concerning the benefit of the online examination program, 41 academies_(51.9%) thought that it was more efficient and less time-consuming. Forty-one academies_(51.9%) were aware of the online examination program, but only 23 academies_(29.1%) were willing to use it. In order to realize an online paper review, there should be appropriate criteria and guidelines for the construction of an online paper review system that suits various types of paper review process employed by the academies. The usability of online information and technology for more efficient and higher-quality judgment should be widely be publicized, and consideration should be given for the types of paper review system that might be suitable for those who are neither aware of the use of the internet nor willing to utilize.
Academies and Institutes
;
Electronic Mail
;
Internet
;
Judgment
;
Korea
;
Surveys and Questionnaires
;
Societies, Medical*
4.Concentration and distribution of tumor associated antigens, TAG-72and CEA, in stomach cancer.
June Key CHUNG ; Myung Chul LEE ; Hong Keun CHUNG ; Chang Soon KOH ; Sang Moo LIM ; Ja Joon JANG
Korean Journal of Nuclear Medicine 1992;26(2):371-379
No abstract available.
Stomach Neoplasms*
;
Stomach*
5.Parenting Stress and Support System in Parents of Child Neuropsychiatric Outpatients.
Ja Yoon KIM ; Dong Hyun AHN ; Bok Ja KOH ; Young Kyo LEE ; Hyo Kyung LEE ; Hye Soon HWANG
Journal of Korean Neuropsychiatric Association 2002;41(6):1130-1141
OBJECTIVES: Parents of child neuropsychiatic patients may have many stresses due to their children's illness. Characteristics and severity of diseases will influence to the stresses of parents. The authors investigated various factors and parents' social support having an effect on the parenting stress. METHODS: Children and parents in outpatients interviewed and completed measures assessing children's problem behaviors, parenting stress, general social support, and support related to parenting by Child Behavior Checklist, Parenting Stress Index, Medical Outcomes Study's Social Support Scale, and Parenting Support Scale. RESULTS: We could not find the differences in the total scores of CBCL, Social Support Scale, and Parenting Stress Index among major diagnostic groups. In the same diagnosis, no difference of parenting stress was found according to general social support. Parenting stress highly correlated with severity of problem behaviors measured by CBCL. CONCLUSION: Severity of problem behaviors perceived by parents most predicted parenting stress. Parenting stress correlated with support to parenting, but not with general social support. Managing of children's problem behaviors is the most immediate and effective method to diminish the parental stress of child neuropsychiatric patients.
Checklist
;
Child Behavior
;
Child*
;
Diagnosis
;
Humans
;
Outpatients*
;
Parenting*
;
Parents*
6.Evaluation of Day Hospital Program in the National Rehabilitation Hospital.
Si Woon PARK ; Ji Young KIM ; Min Joung KANG ; Soon Ja JANG ; Byung Sik KIM ; Kwang Wook KOH
Journal of the Korean Academy of Rehabilitation Medicine 2000;24(5):1002-1009
OBJECTIVE: Day hospital program for the brain injured patients has been developed and conducted as a model project in the National Rehabilitation Hospital of Korea since August 1998. This article is to present our 1-year experience and evaluate the efficacy and effectiveness of the program. METHOD: All patients treated in day hospital from August 1998 to July 1999 were included. Functional Independence Measure (FIM), ESCROW (Environment, Social support, Cluster of family members, Resources, Outlook, Work or School status), Medical Outcome Study 36-item Short Form Survey (SF-36) were assessed at admission and discharge. Patient satisfaction was surveyed at discharge. Program cost was compared with that of inpatient control group. RESULTS: 1) Among 51 subjects (32 males, 19 females, mean age 57), 48 suffered stroke and 2 had traumatic brain injury. Average length of stay was 10 weeks and 45 patients (88.2%) were discharged to home. 2) FIM total score, motor subtotal score and cognitive subtotal score were all incresed significantly (p<0.01). 3) ESCROW score was also improved significantly (p<0.01). 4) SF-36 showed significant improvement in physical functioning, role limitation-emotional, mental health and general health (p<0.05). 5) 95.1% answered satisfaction with the program and 73.2% reported health enhancement. 6) Program costs were significantly lower than the inpatient group (p<0.01). CONCLUSION: Day hospital seems to be a useful program for comprehensive rehabilitation for the brain injured, and needs to be pervaded throughout the country with proper payment.
Brain
;
Brain Injuries
;
Female
;
Humans
;
Inpatients
;
Korea
;
Length of Stay
;
Male
;
Mental Health
;
Outcome Assessment (Health Care)
;
Patient Satisfaction
;
Rehabilitation*
;
Stroke
7.The Trends of Nursing Research in the Journals of Seven Branches of the Korean Academy of Nursing.
Soya Ja KIM ; Kwuy Bun KIM ; Myung Sun YI ; Kwang Ja LEE ; Yang Heui AHN ; Hee Soon KIM ; Young Joo PARK ; Myung Suk KOH ; Kyeong Yae SOHNG
Journal of Korean Academy of Nursing 2002;32(1):114-130
This study was designed to analyze the research methodology and the key concepts used in articles published in each nursing journal of seven branches of the Korean Academy of Nursing. The purpose of this study was for reflecting the trends of nursing research and suggesting the direction of future nursing research in Korea. One thousand three hundred seventy two articles published in seven nursing journals from the beginning year of 2000 were analyzed. The prevailing research designs for these journals were the non-experimental design ranging from 54.3% to 75.7%, the experimental design ranging from 6.2% to 30.4%, and qualitative research design ranging from 3.7% to 10.6%. Research subjects were 10.0% to 46.0% for clients with health problems, 2.1% to 42.4% for generally healthy persons, 1.4% to 43.9% for primary care-givers, 7.0% to 53.5% for nurses or nursing students, and 3.1% to 7.3% for health organizations or nursing organizations. The data collection method used most often self-report questionnaires using psychosocial measures. Interviewing methods and physiologic measures were used relatively few times. The domains of the key concepts that prevailed was personal domain and health domain. This study has the limitation of focusing on only the superficial structural analysis rather than in-depth content analysis of each article. However, this study is the first study for reflecting the trends of nursing research based on each journal of seven branches of the Korean Academy of Nursing.
Data Collection
;
Humans
;
Korea
;
Nursing Research*
;
Nursing*
;
Qualitative Research
;
Surveys and Questionnaires
;
Research Design
;
Research Subjects
;
Students, Nursing
8.Relationship between Job Stress and Pulse Wave Velocity as a Cardiovascular Risk Factor.
Jung Ok KONG ; Sang Baek KOH ; Sei Jin CHANG ; Bong Suk CHA ; Ho Keun CHUNG ; Hong Ryul CHOI ; Kyung Hee JUNG-CHOI ; Soon Ja JEON
Korean Journal of Occupational and Environmental Medicine 2004;16(4):450-458
OBJECTIVE: The objective of this study was to elucidate the relationship between job stress and pulse wave velocity (PWV) as a cardiovascular risk factor. METHOD: The study design was cross-sectional, and a total of 234 industrial workers were recruited. A structured-questionnaire was used to assess the general characteristics and job characteristics (work demand, decision latitude) using a modified Karasek model. Cuffs were applied to the extremities and a microphone for phonocardiography was placed at the second intercostal space at the margin of the sternum. The subjects rested in a supine position for 5 min, and PWV was measured using a VP-1000(Colin Waveform analyzer). RESULTS: There were significant correlations between blood pressure, glucose, total cholesterol, coagulation factor and PWV. The group with low decision latitude and high decision latitude showed higher levels of PWV, but the differences were not significan. The PWV (left) was significantly higher in the high strain group than in the lower strain group. After adjustment for age and cardiovascular risk factors, job strain was still associated with PWV. CONCLUSION: These result suggest that the high strain group among workers is related to an increased risk of PWV as a marker of atherosclerosis.
Atherosclerosis
;
Blood Coagulation Factors
;
Blood Pressure
;
Cholesterol
;
Extremities
;
Glucose
;
Phonocardiography
;
Pulse Wave Analysis*
;
Risk Factors*
;
Sternum
;
Supine Position
9.A Phase II Study to Evaluate the Efficacy of Bortezomib in Combination with Thalidomide in Treatment-Naïve Waldenstrom Macroglobulinemia Patients
Ja Min BYUN ; Junghoon SHIN ; Sang-A KIM ; Hyunkyung PARK ; Jiyun LEE ; Dong-Yeop SHIN ; Junshik HONG ; Jeong-Ok LEE ; Soo-Mee BANG ; Inho KIM ; Sung-Soon YOON ; Youngil KOH
Cancer Research and Treatment 2024;56(2):675-680
Purpose:
Despite the recent success of Bruton’s tyrosine kinase (BTK) inhibitors for the treatment of Waldenstrom macroglobulinemia (WM), their indefinite treatment duration ultimately tantamount to substantial financial and emotional burden. On the other hand, fixed duration of proteasome inhibitors (PI) have shown rapid and reasonable response in WM treatment. Despite the well-known synergism between PI and immunomodulatory drugs (IMiD), there is no trials evaluating such combination in WM.
Materials and Methods:
Based on above, we designed this phase II study to investigate the efficacy and safety of 6 cycles of 28-day bortezomib-thalidomide-dexamethasone (VTD) regimen for treatment-naïve WM.
Results:
A total of 15 patients were enrolled: major response rate was 64.3%, and overall response rate was 78.6%. During the median follow-up of 41 months, median progression-free survival (PFS) was 13 months and overall survival 40 months. For responders, median duration of response was 13 months and median PFS 19 months. The most common adverse event (AE) of any grade was constipation (57.1%). The most common grade ≥ 3 AE was anemia (21.4%).
Conclusion
All in all, we hereby provide proof-of-concept that PI + IMiD may be an attractive backbone for fixed duration treatment. It should be noted that granting the same level of access to newer drugs globally is virtually impossible. Thus efforts to develop regimens using readily available drugs to yield similar or adequate treatment outcomes should not be disregarded. In this sense, we believe our study holds its place for its novelty and eloquently addresses achieving the daunting societal quest of health equity.
10.High Cell-Free DNA Levels in Cerebrospinal Fluid Predict Leptomeningeal Seeding of Hematologic Malignancy
Eun Young KIM ; Soon-Tae LEE ; Young-Sook KIM ; Ja Min BYUN ; Junshik HONG ; Dong-Yeop SHIN ; Youngil KOH ; Inho KIM
Journal of Clinical Neurology 2020;16(4):581-585
Background:
and Purpose: The main difficulty when diagnosing leptomeningeal metastases (LMSs) is the low sensitivity of cytology. Cancer cells release cell-free DNA (cfDNA) during proliferation and apoptosis, and so we analyzed the cfDNA level as a biomarker for LMSs in hematologic malignancy.
Methods:
This study prospectively enrolled 20 patients with hematologic malignancy who underwent cerebrospinal fluid (CSF) analysis. LMS was diagnosed based on both CSF cytology and clinical findings.
Results:
The CSF level of cfDNA was higher in patients with LMSs (108.17±84.84 ng/mL, mean±standard deviation) than in non-LMS patients (14.23±2.78 ng/mL). The sensitivity of cfDNA was higher than that of cytology (100% vs. 87%).
Conclusions
The cfDNA level in the CSF can be used as a supplemental marker for diagnosing LMS in hematologic malignancy patients.