3.Treatment of Pemphigus.
Byung Soon PARK ; Jin Ho CHUNG
Korean Journal of Dermatology 1997;35(3):465-474
BACKGROUND: Pemphigus is a rare, chronic blistering disease of the skin and mucous membranes with severe morbidity and occasional mortality. The clinical data of Korean pemphigus patients are quite limited, and an appropriate treatrnent regimen is not yet established. OBJECTIVE: Our purpose was to analyze the clinical characteristics of, and establish an appropriate treatment regimen for Korean pemphigus patients. METHODS: A retrospective analysis was conducted for 24 pemphigus patients seen between 1992 and 1996. RESULTS: Pemphigus vulgaris(PV) was the most common type with 17 cases, followed by seven cases of pemphigus foliaceus(PF). There were no sexual preferences, and the average age at onset for PV and PF was 46 and 50 years old, respectively. Mucosal involvement was noted in 14 cases(82%) of PV and only in one case(14/o) of PF. There was no correlation between the extent of involvement and the titer of anti ICS(intercellular substance) antibody. Most patients received prednisolone of lmg/kg, and 12 PV patients also received immunosuppressive agents. Systemic side effects were noted in 10 cases of PV, and seven PF cases did not manifest any systemic side effects. CONCLUSIONS: The clinical manifestations and results of imrnunofluorescent studies of 24 Korean pemphigus patients were similar to those of the previous studies. For treatment of pemphigus, the lowest possible doses(less than 1mg/kg) of corticosteroid in combination with immunosuppressive agents appears to be more effective and less toxic than high doses of corticosteroid. We propose a regimen for treatment of Korean pemphigus patients based on these experiences. Further rnulti-center clinical trials are advocated to confirm an effective management protocol for Korean pemphigus patients.
Blister
;
Humans
;
Immunosuppressive Agents
;
Middle Aged
;
Mortality
;
Mucous Membrane
;
Pemphigus*
;
Prednisolone
;
Retrospective Studies
;
Skin
5.A case of squamous cell carcinoma arising in benign cystic teratoma of the ovary.
Kyoung Hee PARK ; Young Ho PARK ; Myeong Soon JEUN ; Young Soon KANG ; Hye Kyeong PARK
Korean Journal of Obstetrics and Gynecology 1993;36(7):3107-3111
No abstract available.
Carcinoma, Squamous Cell*
;
Female
;
Ovary*
;
Teratoma*
6.A Case of Pericarditis as a Complication of Meningococcal Meningitis.
Moo Young OH ; Seung Won PARK ; In Soon PARK ; Chul Ho KIM ; Soon Yong LEE
Journal of the Korean Pediatric Society 1983;26(8):799-802
No abstract available.
Meningitis, Meningococcal*
;
Pericarditis*
7.A Case of Chronic Atrial Tachycardia.
Seung Won PARK ; Moo Young OH ; In Soon PARK ; Chul Ho KIM ; Soon Yong LEE
Journal of the Korean Pediatric Society 1983;26(9):905-908
No abstract available.
Tachycardia*
8.A case of gastroschisis associated with fetal death in utero, and ultrasonographic findings which were in antenatal period.
Myung Soon JEUN ; Young Ho PARK ; Kyung Hee PARK ; Young Soon KANG ; Sang Yoon JEONG
Korean Journal of Obstetrics and Gynecology 1993;36(7):3119-3125
No abstract available.
Fetal Death*
;
Gastroschisis*
9.Coompariso of Alcohol Sclerotherpy with Lapaoscopic Surgery in Patients with Simple Renal Cyst.
Yong Ho JEONG ; Hee Su PARK ; Dae Soon JANG
Korean Journal of Urology 2000;41(10):1271-1276
No abstract available.
Humans
10.A case of Paget's disease of the vulva.
Young Ho PARK ; Myeong Soon JEON ; Chul Hee YOON
Korean Journal of Obstetrics and Gynecology 1993;36(7):1687-1689
No abstract available.
Vulva*
Result Analysis
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