No abstract available.
Humans ; T-Lymphocytes*

No abstract available.
T-Lymphocyte Subsets* ; Thyroid Diseases* ; Thyroid Gland*

BACKGROUND: Pemphigus is a rare, chronic blistering disease of the skin and mucous membranes with severe morbidity and occasional mortality. The clinical data of Korean pemphigus patients are quite limited, and an appropriate treatrnent regimen is not yet established. OBJECTIVE: Our purpose was to analyze the clinical characteristics of, and establish an appropriate treatment regimen for Korean pemphigus patients. METHODS: A retrospective analysis was conducted for 24 pemphigus patients seen between 1992 and 1996. RESULTS: Pemphigus vulgaris(PV) was the most common type with 17 cases, followed by seven cases of pemphigus foliaceus(PF). There were no sexual preferences, and the average age at onset for PV and PF was 46 and 50 years old, respectively. Mucosal involvement was noted in 14 cases(82%) of PV and only in one case(14/o) of PF. There was no correlation between the extent of involvement and the titer of anti ICS(intercellular substance) antibody. Most patients received prednisolone of lmg/kg, and 12 PV patients also received immunosuppressive agents. Systemic side effects were noted in 10 cases of PV, and seven PF cases did not manifest any systemic side effects. CONCLUSIONS: The clinical manifestations and results of imrnunofluorescent studies of 24 Korean pemphigus patients were similar to those of the previous studies. For treatment of pemphigus, the lowest possible doses(less than 1mg/kg) of corticosteroid in combination with immunosuppressive agents appears to be more effective and less toxic than high doses of corticosteroid. We propose a regimen for treatment of Korean pemphigus patients based on these experiences. Further rnulti-center clinical trials are advocated to confirm an effective management protocol for Korean pemphigus patients.
Blister ; Humans ; Immunosuppressive Agents ; Middle Aged ; Mortality ; Mucous Membrane ; Pemphigus* ; Prednisolone ; Retrospective Studies ; Skin

No abstract available.
T-Lymphocyte Subsets* ; Thyroid Diseases* ; Thyroid Gland*

No abstract available.
Carcinoma, Squamous Cell* ; Female ; Ovary* ; Teratoma*

No abstract available.
Meningitis, Meningococcal* ; Pericarditis*

No abstract available.
Tachycardia*

No abstract available.
Fetal Death* ; Gastroschisis*

No abstract available.
Humans

No abstract available.
Vulva*