No abstract available in English.
Clinical Study ; Extremities ; Fractures, Spontaneous

Soft tissues, which are wide spread in body, are derived from a common primitive mesenchyme and the tumors are arising from them tend to closely resemble the prototype tissues in varying degree. Some soft tissue tumors have benign course, which can be cured by local excision and the others have malignant course being resistant to therapy and resulting in recurrence or metastasis to other organs or tissues. The authors reviewed 241 cases of soft tissue tumors which had been received treatment at Department of Orthopedic Surgery in Severance Hospital, Yonsei University College of Medicine from January 1972 to December 1981. The results were obtained as follows: l. Among 241 cases of soft tissue tumors, 202 (83.8%) were benign and 39 (16.2%) were malignant. 2. The most common benign tumor was lipoma (68.7%) which was followed by hemangioma (8.4%), neurofibroma (6.4%) and schwannoma (5.0%) in decreasing order of incidence. Among malignant tumors, fibrosarcoma (35.9%) and rhabdomyosarcoma (33.3%) were the two most common ones, liposarcom (12.8%) and Kaposi's sarcoma (7.7%) being the next common group of tumors. 3. There was no apparent sex preference in benign soft tissue tumors, but in malignant tumors, male was affected about 3 times more common than female. 4. There was no predilection sites in benign tumors, which in malignant tumors, lower extremity was predominant site of occurence. 5. Metastasis of the malignant tumors was taken placed 13 cases (33.3%) at the time of admission, and the lung was the most common frequent site of metastasis. 6. Most of the benign tumors were treated by local excision, and malignant tumors were treated by wide excision with combination of chemotherapy and/or irradiation. 7. Local recurrence of benign tumors was developed in 12 (5.9%) out of 202 cases. 8. Among 19 cases, on follow up examination had been made, 13 survived more than 1 year and 2 cases longer than 5 years after surgery.
Clinical Study ; Drug Therapy ; Female ; Fibrosarcoma ; Follow-Up Studies ; Hemangioma ; Humans ; Incidence ; Lipoma ; Lower Extremity ; Lung ; Male ; Mesoderm ; Neoplasm Metastasis ; Neurilemmoma ; Neurofibroma ; Orthopedics ; Recurrence ; Rhabdomyosarcoma ; Sarcoma, Kaposi

No abstract available.
Hyperplasia* ; Leishmania donovani* ; Leishmania*

No abstract available.
Hyperplasia* ; Leishmania donovani* ; Leishmania*

Carpal tunnel syndrome is most commonly applied to compression neuropathy of the median nerve at the wrist, and is the most cause of buring pain, numbness and tingling in the thumb, index and long fingers, and in the lateral half of the palm, with or without progressive atrophy of the thenar muscles. Fifteen symptomatic hands of 13 patients of the carpal tunnel syndrome managed and operated at the Department of Orthopedic Surgery Severance Hospital from Jan. 1972 to Mar. 1982 were analized in clinical aspect. l. Among 13 patients, 3 were male and 10 were female. 2. Nine patients (69.2%) were affected on dominant hand. 3. Average duration of the symptoms was 17 months. 4. In electromyographic study, conduction delay of the motor fiber of the median nerve was found in 11 cases(73.3%) and sensory fiber in 13 cases(86.6%). Fibrillation of the thenar muscles was found in 11 cases(73.3%). 5. Ten patients, 11 cases were followed up from 11 months to 9 years and 11 months and 72.8% was improved.
Atrophy ; Carpal Tunnel Syndrome ; Clinical Study ; Female ; Fingers ; Hand ; Humans ; Hypesthesia ; Male ; Median Nerve ; Muscles ; Orthopedics ; Thumb ; Wrist

Ossifying fibroma is one of a group of fibro-osseous lesion which arises typically within the jaw bone and only rarely affects the long bones. In 1966, Kempson described two patients with ossifying fibroma of the tibia, noting its unique, aggressive local behavior. This rare lesion resembles monostotic fibrous dysplasia, but can be differentiated from it on histologic and clinical ground. Histologically, ossifying fibroma is characterized by osteoblasstic rimming spicules of bone within a fibrous stroma with evidence of the lamella transformation of bone, and clinically by, frequent recurrence and aggressive progression of the lesion. We experieced three cases of ossifying fibroma, two cases in the tibia and one case in the fibula. In case 1, recurrence was developed after local curettage and bone graft, so reoperation was performed at 11 months after the first opecation. The 2nd case was healed after wide curettage and free vascularized fibula graft, and the 3rd case being followed up after segmental resection of the fibula.
Curettage ; Fibroma ; Fibroma, Ossifying ; Fibrous Dysplasia, Monostotic ; Fibula ; Humans ; Jaw ; Recurrence ; Reoperation ; Tibia ; Transplants

Microinvasive carcinoma of the uterine cervix(Stage Ia) is the earliest stage of squamous carcinoma. The transition from preinvasive to invasive disease is a crucial juncture in the development of cervical cancer. The clinical experience that microinvasive lesions carry a better prognosis justifies a separate diagnostic category. To investigate the clinical and pathological aspects of microinvasive cervical carcinoma, a retrospective study was made on 84 cases, histologically reconfirmed surgical specimens, which had been treated during the period from January, 1985 to December, 1996 at Department of Obstetrics and Gynecology, Kyung-pook National University Hospital. We defined microinvasive carcinoma as stromal invasion not exceeding a depth of Smm from the base of the epithelium presented by FIGO in 1985. The results obtained were as follows; 1. Mean age of 84 patients was 46.9 year old, all were parous women but not 1 patients. 60 cases(71.4%) belonged to stage Ial and 24 cases(28,6%) to stage Ia2. 2. Chief complaints were postcoital spotting and leukorrhea. 3, The corresponding rate of Pap. smear to histologic diagnosis was approximately 29.8%. However correponding rate within one histologic grade was about 33,3%. 4. According to the colposcopic examination, 26.4% of cases revealed suspected abnormal findings suggesting invasive lesion. 5. As to the reports of punch biopsy, 55.1% of cases showed microinvasive and/or invasive lesion. With additional diagnostic conization of cervix, the preoperative diagnosis were correct in 72%. 6. Operation performed were simple hysterectomy, extrafascial hysterectomy or modified radical hysterectomy with both pelvic LN dissection, Simple hysterectomy was most commonly performed. 7. Post-treatment complications were developed in 73.9% of patients who were done with modified radical hysterectomy with both pelvic LN dissection and bladder dysfunction was developed in 50% of the patients.
Biopsy ; Carcinoma, Squamous Cell ; Cervix Uteri* ; Conization ; Diagnosis ; Epithelium ; Female ; Gynecology ; Humans ; Hysterectomy ; Leukorrhea ; Metrorrhagia ; Obstetrics ; Prognosis ; Retrospective Studies ; Urinary Bladder ; Uterine Cervical Neoplasms

No abstract available.
Cryopreservation* ; Humans* ; Spermatozoa*

This study is concerned with a comparison of lower tibial and fibular epiphyseal growth and deformities of the ankles in normal and paralysed children. The data were based on 87 children with residual paralysis due to poliomyelitis an 20 non-paralysed children who were admitted to Severance Hospital and Sam Yook Children's Rehabilitation Center. The difference in level between the lower tibial and fibular ends and between the lower epiphysial lines of the tibia and fibula in X-rays of the ankles were measured in order to investigate the growth pattern of the lower tibio-fibular epiphysis. The difference between the level of the lower ends of the fibula was an avergage of 15.3mm in the normal and 6.2mm in paraysed children. Thus the fibular ends in paralysed limbs was an average of 9.1mm less than that of the normal. The difference between the level of the lower epiphyseal lines of the tibia and the fibula was an average of 13.7mm in normal and 5.5mm in paralysed children. Therefore, the level of the fibular epiphyseal lines in paralysed limbs was sn average of 8.2mm less than that of normal. In paralysed limbs, the lower tibial epiphyses showed lateral epical wedge shaped deformities. The tilting angle of the ankles and the wedging angle of the of the lower tibial epiphyses were measured in erder to investigate the degree of deformities of the ankles and the lower tibial epiphyses in paralysed limbs. The tilting angle of the ankles averaged 1.3° in normal and 7.6° in paralysed limbs. The wedging angle of the lower tibial epiphyses averaged 3.7° in normal and 11.5° in paralysed limbs. In paralysed children, muscle strength examination was performed to clarify the relationship between the degree of growth disturbance and the severity of the muscular paraysis. This lead us to conclude that: 1. In paralysed children, the growth disturbance of the lower fibular epiphyses was greater than that of the lower tibial epiphyses. 2. The difference of the growth disturbance between the tibial and fibular epiphyses was not due to muscle imbalance of the foot invertors and evertors but to muscle weakness. 3. In paraysed children, the shape of the lower tibial epiphyses changed to a wedge shape, a deformity which might be considered secondary to growth disturbance of the fibula. 4. In paralysed children, the lower tibial ends were tilted upward and laterally. This was thought to be the cause of valgus deformities of the ankles. 5. The relationship between the degree of muscle paralysis and the deformities of the ankles was not proved in this study.
Ankle ; Child ; Congenital Abnormalities ; Epiphyses ; Extremities ; Fibula ; Foot ; Humans ; Muscle Strength ; Muscle Weakness ; Paralysis ; Poliomyelitis ; Rehabilitation Centers ; Tibia

Human cytomegalovirus (HCMV)-specific monoclonal antibody, SCMVM 34, recognizes early antigen confined to the nucleus of HCMV-infected cells. This study was performed to identify the antigen reactive to SCMVM 34 with purification and amino acid sequencing. The nuclear and cytoskeletal fraction of HCMV-infected cells was subjected to 0.4 M NaCl extraction, DEAE-Sephacel ion exchange chromatography, DNA-cellulose chromatography and SDS-PAGE. The molecular weight of the reactive proteins was 52 kD, 40 kD and 34 kD. The modified or blocked amino termini of 52 kD and 40 kD showed resistance to Edman degradation. The internal peptide fragments were isolated by tryptic digeytion and reverse-phase HPLC. The internal amino acid sequence analysis of the peptides from HPLC profile revealed that the antigens recognized by SCMVM 34 was ppUIA4.
Chromatography ; Chromatography, High Pressure Liquid ; Chromatography, Ion Exchange ; Cytomegalovirus* ; Electrophoresis, Polyacrylamide Gel ; Humans* ; Molecular Weight ; Peptide Fragments ; Peptides ; Sequence Analysis, Protein