No abstract available.

No abstract available.
Cryopreservation* ; Trachea*

BACKGROUND: Oxygen concentrators are convenient to operate and economical for patients with chronic obstructive pulmonary disease (COPD). However, oxygen concentrators are not manufactured domestically and the COPD patients are currently treated with imported oxygen concentrators. To evaluate the efficacy and safety of domestically developed prototype oxygen concentrator before clinical application, the efficacy and safety of the domestic oxygen concentrator were evaluate by comparing with the imported one. Meterial and METHODS: The clinical tests were performed on 36 hyperhydrosis patients from April 1999 to August 1999. Domestic and imported oxygen concentrators were in turn applied to the same patient, who inspired oxygen for 60 minutes at a rate of 3 liters per minute through nasal prong. The oxygen concentrator, which was applied first, was randomly allocated. The arterial partial oxygen pressure (PaO2) was estimated to compare the efficacy; and the carboxy hemoglobin(COHb), pH, arterial CO2 partial pressure, pulse rate, blood pressure, and respiration rate to compare the safety before and after applying each oxygen concentrator. A student t-test was used to analyze the results. RESULTS: In respect to efficacy, the difference in the change of PaO2 before and after the application between two concentrators was not statistically significant. In respect to safety, the differences in the changes of COHb, pH, partial pressure of arterial CO2, pulse rate, blood pressure, respiration rate between two concentrators were also not statistically significant. CONCLUSION: The domestically developed oxygen concentrator, showed satisfactory efficacy and safety when compared with the imported one.
Blood Pressure ; Heart Rate ; Humans ; Hydrogen-Ion Concentration ; Oxygen* ; Partial Pressure ; Pulmonary Disease, Chronic Obstructive ; Respiratory Rate

No abstract available.
Thoracic Surgery, Video-Assisted*

No abstract available.
Esophageal Neoplasms*

No abstract available.
Biopsy, Fine-Needle* ; Lung Neoplasms* ; Lung* ; Thoracic Wall* ; Thorax*

Ischemia reperfusion injury is a major contributing cause to early graft failure in lung transplantation. To develop a new and more improved preservation solution for lung transplantation, we formulated basic compositions of new solution made by adding several additives to extracellular type dextran solution. The aim of this study was to compare the preservation effect of this newly composed solution (group 2) to that of the Euro-Collins solution (group 1) on postischemic lung function in a canine left lung transplantation model. Six adult mongrel dogs were used as subjects for left lung allotransplantation. Three donor dogs were flushed with the new solution (Group 2, n=3), while the remaining three were flushed with the Euro-Collins solution, serving as the control (Group 1, n=3). The allografts were stored in each preservation solution at 4oC. Left single lung transplantations were performed. After left lung allotransplamtation, lung functions were assessed at 10, 30, 60, and 120 min after reperfusion. Although better arterial oxygen tensions were observed in group 2, they were not statistically significant. The mean pulmonary arterial pressure showed no difference between two groups. Even though pulmonary vascular resistances were slightly higher in group 2, their differences showed no statistical significance. Autopsy findings revealed findings of pulmonary venous occlusion by thrombi and bronchial obstruction by granulation tissue in two cases of group 2. But it seemed that those findings were due to surgical failures or rejections rather than primary graft failures resulting from poor preservation. Compared to the Euro-Collins solution, the new solution demonstrated comparative allograft preservation in canine single left lung transplantation models. We concluded that this new solution could be used as a basic composition for the future development of ideal preservation solution.
Adult ; Allografts ; Animals ; Arterial Pressure ; Autopsy ; Dextrans ; Dogs ; Granulation Tissue ; Humans ; Lung Transplantation ; Lung* ; Organ Preservation ; Oxygen ; Potassium* ; Reperfusion ; Reperfusion Injury ; Tissue Donors ; Transplants

No abstract available.
Amniotic Fluid* ; Female ; Humans ; Obstetric Labor, Premature* ; Pregnancy ; Pregnant Women*

We report a case of epidermolysis bullosa acquisita in a 53 year-old woman who had. extreme skin fragility, trauma induced blisters and erosions usually localized to extensor site of the skin surface, and healing with scars and milia for several years. Histologic findings of perilesional skin showed normal epidermis, subepid malblister and spirsely infiltration of inflammatory cells. Direct immuncofluorescence showed depositiori of IgCi and C3 in a linear pattern along the epidermal basement, membrane in the per ilesional skin. In indirect immuriofluorescence, using 1.0M sodium chloride separated nor mal human skin as the sntbstrate, antitodies(IgG at a titer of 1:40) were bound to dermal site of the separation, indicating that the patient serum yields the reaction in or below the lamiria densa. Electronmicroscopic findings showed the roof of the blister was located. below the basal lamiria.
Blister ; Cicatrix ; Epidermis ; Epidermolysis Bullosa Acquisita* ; Epidermolysis Bullosa* ; Female ; Humans ; Membranes ; Middle Aged ; Skin ; Sodium Chloride

No abstract available.
Child* ; Humans ; Prone Position* ; Thoracotomy*