1.Factors Influencing Complications after Therapeutic Lung Resection in Lung Cancer Patients
Journal of Korean Academy of Fundamental Nursing 2020;27(2):106-115
Purpose:
The purpose of this study was to assess postoperative complications and factors influencing complications in lung cancer patients undergoing therapeutic lung resection.
Methods:
This was a retrospective comparative study investigating participants’ individual characteristics, nutritional status, operative characteristics, and disease characteristics as found in the electronic medical records of patients undergoing therapeutic lung resection for lung cancer. Data were collected from 191 participants who received the therapeutic lung resection in 1 general hospital. Analysis was done using x2 test or independent t-test, Pearson correlation and multiple regression analysis.
Results:
The incidence of complications according to the characteristics of the patients was significantly higher for men over 65 years old, smokers (former smokers included), FEV1/FVC ratio less than 70%. Other factors influencing outcomes were lengthy operation time, FEV1/FVC ratio less than 70% and post OP stageII.
Conclusion
Results show that a FEV1/FVC ratio less than 70%, and post OP stageII are factors influencing complications after therapeutic lung resection. Determination of chronic obstructive pulmonary disease through preoperative pulmonary function tests and plans to provide nursing interventions that improve lung function contribute to prevention of postoperative complications.
2.Clinical Findings of Menkes Disease and the Treatment of Epilepsy.
Min Hye CHOI ; Soojin KIM ; Sun Whan BAE ; Jae Sung SON ; Ran LEE
Journal of the Korean Child Neurology Society 2018;26(2):109-112
Menkes disease (also known as kinky hair disease) is an X-linked recessive neurodegenerative disorder caused by diverse mutations in a copper-transport gene, ATP7A. Affected patients are characterized by kinky hair, hypotonia, and generalized myoclonic seizures. Here, we report a case of Menkes disease in which the patient presented with progressive hypotonia and intractable seizures. A 4-month-old male infant visited our pediatric clinic for focal seizures with blinking eyes. He was generally hypotonic and suffered from malnutrition. The focal seizures became more frequent, and the patient became intractable to anti-seizure medications. An electroencephalogram (EEG) indicated diffuse cerebral dysfunction with focal seizure, and a brain magnetic resonance imaging (MRI) showed tortuous and ectatic intracranial arteries, as well as several ischemic lesions. A genetic analysis was performed, and a c.2473_2474del (p.Leu825fsX1) of the ATP7A gene was detected.
Arteries
;
Blinking
;
Brain
;
Electroencephalography
;
Epilepsy*
;
Hair
;
Humans
;
Infant
;
Magnetic Resonance Imaging
;
Male
;
Malnutrition
;
Menkes Kinky Hair Syndrome*
;
Muscle Hypotonia
;
Neurodegenerative Diseases
;
Seizures