1.Association of Work-Time, Leisure-Time Physical Activity and Osteoporosis Prevalence: Korea National Health and Nutrition Examination Survey in 2015–2016
Mikyung LEE ; Rina JUNG ; Yoonyoung JUNG ; Jahyeun HO ; Hyoungmin KIM ; Junga KIM ; Soohyoung LEE ; Ki Hyun PARK
Korean Journal of Family Practice 2019;9(5):403-407
BACKGROUND: Physical activity is an important factor for preventing osteoporosis. This study aimed to investigate the association of work- and leisure-time physical activities with osteoporosis in postmenopausal women.METHODS: Data were obtained from the Korea National Health and Nutritional Examination Survey 2015–2016. A total of 2,885 postmenopausal women were included in the analysis. The subjects were divided into 3 groups according to the intensity of the work- and leisure-time physical activities. T-test, chi-square test, and multivariable logistic regression analysis were used.RESULTS: No association was found between work-time physical activity and osteoporosis prevalence. However, a dose-response relationship was found in case of leisure-time physical activity. People with leisure-time physical activity of at least >1,000 MET-min/week showed lower prevalence of osteoporosis.CONCLUSION: An appropriate level of leisure-time physical activity should be recommended to prevent and treat osteoporosis.
Female
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Humans
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Korea
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Leisure Activities
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Logistic Models
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Motor Activity
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Nutrition Surveys
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Osteoporosis
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Prevalence
2.Use of Haloperidol and Lorazepam for Intractable Symptoms in the Hospice Palliative Care Unit
Wook NAMKOONG ; Jungmin KIM ; Hyunseon EO ; Eunjin CHUNG ; Junga KIM ; Soohyoung LEE ; Kihyon PARK
Korean Journal of Family Practice 2019;9(1):10-16
BACKGROUND: Terminally ill cancer patients suffer from refractory symptoms, and the last option of treatment is to consider sedatives. However, due to concerns that sedation may shorten survival time, some people prefer not to take sedatives. The purpose of this study was to investigate the effects of sedative administration on survival time among terminally ill cancer patients.METHODS: Two hundreds and thirty-seven patients who were hospitalized to the hospice care unit of public hospitals in Seoul from January, 2015 to March, 2016 were analyzed retrospectively. The univariate and multivariate Cox's proportional hazard regression model was used to determine independent factors related to survival time.RESULTS: The usage of sedation was necessary because the incidence of insomnia was 61.4% in the lorazepam only group, and the incidence of delirium was highest in the haloperidol group and the haloperidol with lorazepam group. Interestingly, multivariate analysis showed that male (HR, 1.766; P < 0.001), decreased consciousness (HR, 1.803; P=0.003), anorexia (HR, 1.506; P=0.012), resting dyspnea (HR, 1.757; P < 0.001), elevated serum bilirubin (HR, 1.657; P=0.001), and the haloperidol with lorazepam group (HR, 0.535, P < 0.001) were each significantly associated with survival time. Furthermore, patients in the haloperidol with lorazepam group survived longer than patients with no such medications.CONCLUSION: There is no evidence that treatment with sedative medication shortens the survival time of patients with terminally ill cancer with refractory symptoms.
Anorexia
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Bilirubin
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Consciousness
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Delirium
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Dyspnea
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Haloperidol
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Hospice Care
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Hospices
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Hospitals, Public
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Humans
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Hypnotics and Sedatives
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Incidence
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Lorazepam
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Male
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Multivariate Analysis
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Palliative Care
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Retrospective Studies
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Seoul
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Sleep Initiation and Maintenance Disorders
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Terminally Ill