Objectives: Currently, more than 80% of Korean police officers are assigned to a 24-hour rotating shift system. Shift workers’ sleep patterns change frequently, which may result in circadian rhythm desynchrony and sleep disturbance. The goal of this study was to compare sleep and cognitive functioning in different shift types. In addition, we analyzed the difference in cognitive functioning depending on whether shift workers took a night nap prior to their night shift. Methods: A total of 278 police officers working in Seoul (mean age 45.27±9.00 years, 88.5% male) participated, providing demographic information and completing selfreport questionnaires [Insomnia Severity Index, Epworth Sleepiness Scale, Munich ChronoType Questionnaire (Shift-work type), Patient Health Questionnaire-9]. Participants also performed the Psychomotor Vigilance Task, Trail Making Test A & B, and Stroop Test. Results: Participants included 57 (20.5%) day workers and 221 (79.5%) shift workers. The average Insomnia Severity Index score of shift workers was significantly higher than day workers (t=-2.861, p=0.005). Shift workers also slept about 0.78 hours less than day workers (t=4.730, p<0.001). Among shift workers, 66.3% (n=128) reported they took night naps prior to their night shift, sleeping on average 1.78 hours. Shift workers who took night naps had faster reaction times on the Trail Making Test A task [F(1, 136)=5.741, p=0.018], and significantly fewer Stroop C errors [F(1, 137)=5.638, p=0.019] than those who did not. Conclusions Shift working police officers reported significantly worse insomnia symptoms and slept less compared to their non-shift-working counterparts. Taking a night nap improved focused and selective attention.

Objectives: Currently, more than 80% of Korean police officers are assigned to a 24-hour rotating shift system. Shift workers’ sleep patterns change frequently, which may result in circadian rhythm desynchrony and sleep disturbance. The goal of this study was to compare sleep and cognitive functioning in different shift types. In addition, we analyzed the difference in cognitive functioning depending on whether shift workers took a night nap prior to their night shift. Methods: A total of 278 police officers working in Seoul (mean age 45.27±9.00 years, 88.5% male) participated, providing demographic information and completing selfreport questionnaires [Insomnia Severity Index, Epworth Sleepiness Scale, Munich ChronoType Questionnaire (Shift-work type), Patient Health Questionnaire-9]. Participants also performed the Psychomotor Vigilance Task, Trail Making Test A & B, and Stroop Test. Results: Participants included 57 (20.5%) day workers and 221 (79.5%) shift workers. The average Insomnia Severity Index score of shift workers was significantly higher than day workers (t=-2.861, p=0.005). Shift workers also slept about 0.78 hours less than day workers (t=4.730, p<0.001). Among shift workers, 66.3% (n=128) reported they took night naps prior to their night shift, sleeping on average 1.78 hours. Shift workers who took night naps had faster reaction times on the Trail Making Test A task [F(1, 136)=5.741, p=0.018], and significantly fewer Stroop C errors [F(1, 137)=5.638, p=0.019] than those who did not. Conclusions Shift working police officers reported significantly worse insomnia symptoms and slept less compared to their non-shift-working counterparts. Taking a night nap improved focused and selective attention.

OBJECTIVES: The current study aimed to investigate individuals with night eating syndrome tendency in 115 female undergraduate sample based on night eating syndrome criteria, and analyze its association between mood, sleep, and alcohol use. METHODS: Subjects were divided into high and low tendency group of night eating syndrome based on the night eating questionnaire. All participants completed the Hospital Anxiety and Depression Scale, Insomnia Severity Index, Munich Chronotype Questionnaire, and Alcohol-Use Disorders Identification Test. Data was collected at two time points which were 3 months apart. All analyses were conducted using repeated measure ANOVA. RESULTS: Results indicated a significant difference between night eating syndrome tendency groups for anxiety and depression [F(1,113)=12.35, p=0.001 and F(1,113)=9.59, p=0.002, respectively]. Depression also had a significant time effect [F(1,113)=11.15, p=0.001]. Additionally, the high night eating syndrome tendency group had higher levels of insomnia severity [F(1,113)=24.34, p<0.001], eveningness [F(1,113)=15.09, p<0.001], and alcohol use [F(1,113)=6.73, p=0.011], and lower sleep efficiency [F(1,113)=6.30, p=0.014] compared to the low night eating syndrome tendency group. CONCLUSIONS: The high night eating syndrome tendency group had higher negative mood, sleep disturbance, and alcohol use compared to the low night eating syndrome tendency group. In summary, intervention for night eating syndrome may be important to consider in undergraduate students.
Alcohol Drinking ; Anxiety ; Circadian Rhythm ; Depression ; Eating* ; Feeding and Eating Disorders ; Female* ; Humans ; Sleep Initiation and Maintenance Disorders

OBJECTIVES: The current study aimed to explore the difference of dream themes, emotional intensity, and sleep parameters between nightmares and bad dreams in nightmare sufferers. METHODS: Twenty-four nightmare sufferers who endorsed clinical levels of nightmares (Disturbing Dream and Nightmare Severity Index Scores ≥10) recorded daily information about their dream themes using a modified version of the Typical Dreams Questionnaire, emotional intensity about their nightmares and bad dreams, and sleep for two weeks on a mobile device. RESULTS: Evil presence (35%) was reported with higher frequency in nightmares, whereas interpersonal conflicts (31%) were predominantly reported in bad dreams. Nightmares were rated substantially more emotionally intense than bad dreams. Especially, fear (Z=-2.118, p=0.034) was rated as being significantly higher in nightmares than bad dreams. There were differences on time in bed, wake after sleep onset, sleep efficiency on the days with nightmares or bad dreams compared to other days; however, there were no differences in sleep parameters between nightmares and bad dreams. CONCLUSIONS: The results suggest that nightmares may be qualitatively and quantitatively different from bad dreams in nightmare sufferers.
Dreams*

OBJECTIVES: The current study aimed to explore the relationship between subjective sleep, emotions, social support and excessive daytime sleepiness (EDS), and extract the strongest predictor of EDS in female undergraduate students. METHODS: Our subjects consisted of 168 female undergraduate students (mean age 21.64±1.66). All participants completed Epworth Sleepiness Scale (ESS), Insomnia Severity Index, Hospital Anxiety and Depression Scale, Social Support Scale, and the Munich Chronotype Questionnaire. RESULTS: There were significant associations between insomnia, anxiety, depression with EDS, but not with subjective total sleep time of workdays and freedays. Also, 23.8% (n=40) of subjects endorsed clinical levels of EDS (ESS>10). Insomnia, anxiety, and depression were higher, and social support was lower in the EDS group compared to the normal group. Finally, we explored factors that influenced EDS, resulting in anxiety and social support being the strongest predictors of EDS. Social support was the strongest predictor of EDS compared to other predictors (β=-0.276, p<0.001). CONCLUSIONS: Results suggest that social support may be important to consider in female undergraduate students who experience EDS.
Anxiety ; Depression ; Female* ; Humans ; Sleep Initiation and Maintenance Disorders

PURPOSE: Viral gastroenteritis is a common disease in infants and children. Seizures can be associated with viral gastroenteritis as benign convulsions with mild gastroenteritis (CwG). After the development of the rotavirus vaccination, norovirus has become inreasingly significant in children. We retrospectively analyzed the clinical features in a pediatric population presenting with seizures and confirmed enteral viral infections, especially norovirus infections. METHODS: We retrospectively reviewed the medical records of pediatric patients aged < 15 years admitted due to convulsions and gastroenteritis to the Department of Pediatrics of Myongji Hospital between July 2014 and June 2016. RESULTS: A total of 46 patients (24 male and 22 female) were included. Norovirus was detected in 21 (45.7%) patients, adenovirus in three (6.5%), rotavirus in two (4.3%), astrovirus in one (2.2%), and none of agents were detected in 19 (41.3%) patients. Patients in the norovirus gastroenteritis (NGE) group had a higher incidence of diarrhea than that among in the non-norovirus gastroenteritis (NNGE) group (61.9% vs 28.0%; P < 0.05). Twelve patients experienced status epilepticus, including five (23.8%) in the NGE group and seven (33.0%) in the NNGE group (P=0.837). Seizures were effectively terminated by intravenous benzodiazepines in 8 (66.7%) of 12 patients. Additional long-acting antiepileptic drugs such as fosphenytoin or levetiracetam were required in three (25%) of 12 patients. CONCLUSION: Patients with CwG with and without noroviurs infection did not differ in terms of clinical features. However, status epilepticus was not uncommon among patients with CwG by definition.
Adenoviridae ; Anticonvulsants ; Benzodiazepines ; Child* ; Diarrhea ; Gastroenteritis* ; Humans ; Incidence ; Infant ; Korea* ; Male ; Medical Records ; Norovirus ; Pediatrics ; Retrospective Studies ; Rotavirus ; Seizures* ; Status Epilepticus ; Vaccination

Purpose: To compare the refractive outcomes of closed C-loop and C-loop intraocular lenses (IOLs) following phacovitrectomy with gas tamponade. Methods: Medical records of 42 patients (43 eyes) who underwent phacovitrectomy with gas tamponade for idiopathic macular holes between January 2021 and June 2022 were retrospectively reviewed. Closed C-loop (26 eyes; Eyelike K-flex Aspheric®, Koryo Eyetech, Seoul, Korea) and C-loop (17 eyes; Tecnis® ZCB00, Johnson & Johnson Vision, Santa Ana, CA, USA) IOLs were surgically implanted. The main outcome measures were postoperative prediction error and absolute error. Results: There was no significant difference in mean absolute error at 5 months postoperatively (0.34 ± 0.24 diopters [D] and 0.30 ± 0.25 D in the closed C-loop and C-loop IOL groups, respectively; p = 0.502). The mean prediction error at 5 months postoperatively also showed no significant difference between the groups (-0.28 ± 0.30 D and -0.16 ± 0.36 D, respectively; p = 0.242). Myopic shift was observed in both groups. Conclusions There was no significant difference in refractive outcomes between closed C-loop IOLs and C-loop IOLs. A myopic shift was observed in both groups; this should be taken into consideration when calculating IOL power following phacovitrectomy with gas tamponade.

Purpose: Various vitrectomy probes are currently being used commercially, and there are ongoing efforts toward developing probes with higher cutting rates and smaller gauges. This study aimed to compare the efficiency and safety of various commercially available small gauge ultrahigh-speed dual pneumatic vitrectomy probes. Methods: We retrospectively analyzed the medical records of patients and recorded intraoperative videos while they underwent microincision three-port vitrectomy surgery for idiopathic epiretinal membrane at Soonchunhyang University Seoul Hospital. The patients were categorized into four groups based on the vitrectomy probe used during surgery: 23-7500 (UltraVit 23-gauge 7,500 cuts per minute [CPM]), 23-7500 (UltraVit 25-gauge 7,500 CPM), 25-10K (Advanced UltraVit 25-gauge 10,000 CPM), and 27-10K (Advanced UltraVit 27-gauge 10,000 CPM). Results: In total, 82 eyes from 82 patients were included in this work, with 16, 11, 26, and 29 eyes in groups 23-7500, 25-7500, 25-10K, and 27-10K, respectively. The corresponding vitrectomy times were 295.56 ± 53.55, 293.09 ± 50.28, 299.92 ± 59.42, and 349.38 ± 67.23 seconds, respectively. There was a significant difference in the vitrectomy time between the groups (p = 0.004). The mean number of sutures was 3, 3, 2.96, and 0.83, respectively. In the 23-7500 group, there was one case of iatrogenic retinal break, while in the 27-10K group, there was one case of postoperative hypotony. Conclusions Although advancements have been made in the 27-gauge vitrectomy probe, it still takes more vitrectomy time than it does when using the 23- and 25-gauge probes. However, the delay was within an average of 1 minute, and considering the significantly reduced need for sutures, there is a substantial benefit in terms of postoperative discomfort. Therefore, when choosing a probe for epiretinal membrane surgery among the four options, it is reasonable to select the 27-gauge probe according to the surgeon’s preference.

Despite substantial progress in screening, early diagnosis, and the development of noninvasive technology, gastrointestinal (GI) cancer remains a major cause of cancer-associated mortality. Chemoprevention is thought to be a realistic approach for reducing the global burden of GI cancer, and efforts have been made to search for chemopreventive agents that suppress acid reflux, GI inflammation and the eradication of Helicobacter pylori. Thus, proton pump inhibitors, statins, monoclonal antibodies targeting tumor necrosis factor-alpha, and nonsteroidal anti-inflammatory agents have been investigated for their potential to prevent GI cancer. Besides the development of these synthetic agents, a wide variety of the natural products present in a plant-based diet, which are commonly called phytoceuticals, have also sparked hope for the chemoprevention of GI cancer. To perform successful searches of chemopreventive agents for GI cancer, it is of the utmost importance to understand the factors contributing to GI carcinogenesis. Emerging evidence has highlighted the role of chronic inflammation in inducing genomic instability and telomere shortening and affecting polyamine metabolism and DNA repair, which may help in the search for new chemopreventive agents for GI cancer.
Anti-Inflammatory Agents, Non-Steroidal ; Antibodies, Monoclonal ; Biological Agents ; Chemoprevention ; Diet ; DNA Repair ; Early Diagnosis ; Gastrointestinal Neoplasms ; Genomic Instability ; Helicobacter pylori ; Inflammation ; Mass Screening ; Proton Pump Inhibitors ; Telomere Shortening ; Tumor Necrosis Factor-alpha