No abstract available.
Syringoma

No abstract available.

In the field of psychiatry, studies on circadian rhythms are increasing. This research trend is based on the emerging evidence on the relationship between circadian rhythm and pathophysiology and prognosis of psychiatric disorders.As performing the research on this area, the difficulty in analyzing large amount of data that are sequentially collected according to time change exists. In order to properly analyze the data in research on the circadian rhythm, it is necessary to effectively apply analysis methods of time series data. Therefore, this review aimed to summarize the analysis methods of circadian rhythms that show time series data. Understanding the analysis method of circadian rhythm will be useful for utilizing clinical data in the form of a time series data in the smart medical field in the future.

The circadian rhythms have been gradually important in psychiatric field. Several studies have shown that major psychiatric disorders, such as schizophrenia, bipolar disorders, and dementia, were highly associated with the abnormalities of circadian rhythms. Circadian rhythms might have an influence on the pathogenesis and prognosis of psychiatric disorders. Understanding the impact of circadian rhythms on psychiatric disorders became crucial to psychiatrists. Therefore, this review investigated the types of the circadian rhythms to be used in psychiatric field. The measurement of circadian rhythms were performed by several ways, such as sleep diary, self-reported scales, heart rate, heart rate variability, polysomnography, electroencephalography, actigraphy, melatonin, cortisol. Using these data related to circadian rhythms might be utilized to evaluate the relevance of the pathogenesis in psychiatric disorders and predict the treatment response and prognosis of illness. Furthermore, if the real-time monitoring of circadian rhythms is possible, the novel diagnostic and therapeutic model using circadian rhythms could be applied in psychiatric area.

OBJECTIVE: To evaluate the basophil histamine releasability in response to IgE- and non- IgE-mediated stimuli in children with atopic asthma. Met: Basophil histamine releasability was measured in Dermatophagoides farinae (D. farinae)-sensitive atopic asthmatics, D.farinae-sensitive healthy atopics, non-atopic asthmatics, and healthy non-atopics. Basophils were stimulated with D.farinae, goat antihuman IgE antibody, formyl-Met-Leu-Phe(fMLP), and Calcium ionophore A23187. Histamine was measured by automated fluorometric technique. RESULTS: Sponianeous histamine release was higher in atopic asthmatics compared to healthy non-atopics. Histamine release by D.farinae and by anti-IgE antibody was higher in atopic asthmatics compared to the other groups. There was no difference in histamine release by fMLP among all groups. Histamine release by Calcium ionophore was higher in healthy atopics and non-atopic asthmatics compared to healthy non-atopics. The atopics showed correlation between histamine release by D.farinae, by anti-IgE antibody and total serum IgE levels. CONCLUSIONS: Spontaneous and IgE-mediated histamine release were related to the presence of both atopy and asthma, whereas non-IgE mediated histamine release was different depending on the stimuli.
Asthma* ; Basophils* ; Calcimycin ; Calcium ; Child* ; Dermatophagoides farinae ; Goats ; Histamine Release ; Histamine* ; Humans ; Immunoglobulin E

No abstract available.
Arteriovenous Fistula* ; Telangiectasia, Hereditary Hemorrhagic*

No abstract available.
Humans ; Infant* ; Streptococcal Infections*

No abstract available.
Angiomyolipoma* ; Lymph Nodes*

Coronary spasm may be induced by a variety of physiologic and pharmacologic stimuli but specific receptor blockade has not been consistently shown to prevent the attacks. Most patients with variant angina respond well to treatment with calcium antagonists and nitrates. A small proportion of patients are refractory to this therapy. We report a case of the patient with a 9-year-history of variant angina who has been refractory to high doses of calcium antagonists and nitrates. The repeated addition of clonidine was consistently effective in abolishing both symptoms and objective evidence of myocardial ischemia in this particular patient.
Calcium ; Clonidine* ; Humans ; Myocardial Ischemia ; Nitrates ; Spasm

BACKGROUND: Morphine has been commonly used for postoperative pain control. We measured plasma concentrations of morphine and compared the efficacy and safety of continuous epidural analgesia (CEA) using morphine-bupivacaine with intravenous patient controlled analgesia (IV-PCA) with morphine for 48 hrs after the end of the operation. METHODS: Nineteen patients undergoing Mile's operation were assigned to receive a morphine loading dose of 5 mg followed by IV-PCA with 0.1% morphine (IV-PCA group, n = 9) or a morphine loading dose of 2 mg and 0.125% bupivacaine 10 ml, followed by CEA with 0.004% morphine and 0.075% bupivacaine at a rate of 5 ml/hr (CEA group, n = 10). The plasma concentrations of morphine were measured and visual analog scales (VAS) for pain were recorded at 1, 6, 12, 24, and 48 hr postoperatively and the effects on respiration and any other side effects were noted. RESULTS: The mean maximal and minimal levels of plasma morphine were 40.2 +/- 21.2 ng/ml and 23.4 +/- 9.7 ng/ml for the IV-PCA group and 11.8 +/- 3.5 ng/ml and 8.2 +/- 1.9 ng/ml for the CEA group, respectively. Resting and dynamic pain scores were significantly lower in the CEA group than in the IV-PCA group. There were no significant differences for the effects on respiration and for any side effects between the two groups. CONCLUSIONS: We evaluated plasma concentrations of morphine with CEA using morphine-bupivacaine and IV-PCA using morphine for the postoperative pain control. The CEA group had better postoperative analgesia than that of the IV-PCA group and the incidence of side effects were not significantly different between the two groups.
Analgesia ; Analgesia, Epidural ; Analgesia, Patient-Controlled ; Bupivacaine ; Humans ; Incidence ; Morphine ; Pain, Postoperative ; Plasma ; Respiration ; Weights and Measures