1.A Clinical Study and the Histamine Test in Patients with Herpes Zoster.
Yean Sub JANG ; Jong Min KIM ; Eil Soo LEE
Korean Journal of Dermatology 1988;26(6):846-853
We studied 283 patients with herpes zoster who visited to the Hangang Sacred Heart Hospital between January, 1982 and December, 1985 about the distribution of age, sex, seasonal incidence, associated diseases, camplications and the effect of systemic prednisolone on post herpetic neuralgia. And we also examined the functional states of involved sensory nerve endings by observing the axon flare response to histamine test. The results were as follows . 1. There was no significant differences in sexual and seasonal distributions. 2. There were low incidences of herpes zoster in age groups of below 20 years and over 70 years than age groups of 20 69 years. 3. Sites of involvement were thoracic(170 cases), cervical(38 cases), trigeminal(35 cases), lumbar(28 cases), sacral(11 cases) and facial(1 case) dermatomes. 4. Associated diseases were diabetes mellitus(7 cases), hypertension(7 cases). pulmonary tuberculosis(6 cases), malignant neoplasms(3 cases) and renal transplantation (1 case). 5. Complications were post herpetic neuralgia(18 cases), keratoconjunctivitis(9 cases), meningoencephalitis(1 case), Ramsay Hunt syndrome(1 case), urinary difficulty(1 case) and generalized varicelliform eruption(1 case). 6. The incidence of post-herpetic neuralgia was reduced by systemic prednisolone therapy in patients over 60 years. 7. There was no decrease of axon flare by histamine test on the affected area in 18 patients with herpes zoster.
Axons
;
Heart
;
Herpes Zoster*
;
Histamine*
;
Humans
;
Incidence
;
Kidney Transplantation
;
Neuralgia
;
Prednisolone
;
Seasons
;
Sensory Receptor Cells
2.The Relationship between Change of Lymphocyte Inositol Monophosphatase mRNA Level by Lithium and Clinical Course in Bipolar Affective Disorder.
Seok Hyeon KIM ; Min Soo LEE ; Jang Han LEE
Journal of the Korean Society of Biological Psychiatry 2001;8(1):96-105
OBJECTIVE: Lithium inhibits the action of inositol monophosphatase(IMPase) in phosphoinositide(PI) signal transduction system at therapeutically relevant concentration. The depletion of inositol by lithium itself cannt explain the lithium's therapeutic effect. However, attention has focused on the abnormality of PI signal transduction system as the pathophysiology of bipolar affective disorder(BPD). We investigated whether IMPase mRNA levels of lymphocytes would be different between BPD patients(n=16) and age, sex-matched normal controls(n=16). We also investigated the change of IMPase mRNA level by lithium during 4 weeks to probe the possibility that IMPase mRNA levels could predict the therapeutic response to lithium and clinical course. METHOD: Relative IMPase mRNA levels in lymphocyte were quantified by reverse transcriptase(RT)-PCR in sixteen drug-free BPD patients and sex, age-matched normal controls. The psychopathology of patients were measured using YMRS(Young Mania Rating Scale) and CGI(Clinical Global Impression). RESULTS: There was no significant difference in IMPase mRNA levels between BPD patients and normal controls. And the IMPase mRNA levels were not significantly changed by 4 week treatment with lithium. However, the basal IMPase mRNA levels were negatively correlated with the changes of CGI after 4 weeks. Furthermore, the patients with relatively high basal IMPase mRNA levels showed much more improvement during 4 weeks. CONCLUSIONS: BPD patients and normal controls were not distinguished by lymphocyte IMPase mRNA level. Although we do not support the hypothesis that lymphocyte IMPase activity would be related with the pathogenesis of BPD and the action of lithium, these data raise the possibility that lymphocyte IMPase mRNA levels could function as a predictor of therapeutic response and clinical course of BPD.
5'-Nucleotidase
;
Bipolar Disorder
;
Humans
;
Inositol*
;
Lithium*
;
Lymphocytes*
;
Mood Disorders*
;
Psychopathology
;
RNA, Messenger*
;
Signal Transduction
3.A Case of Hypopigmented Mycosis Fungoides.
Min Soo JANG ; Joon Sung YANG ; Young Soo CHAE ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1997;35(1):196-199
No abstract available
Mycosis Fungoides*
4.Upper limb salvage using free forearm flap harvested from the non-replantable amputation part: cases report.
Woo Young JANG ; Rong Min BAEK ; Soo Shin KIM ; Se Min BAEK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(6):1148-1152
No abstract available.
Amputation*
;
Forearm*
;
Upper Extremity*
5.A study on osteoblast-like cell responses to surface-modified titanium.
Min ah HONG ; Yung Soo KIM ; Chang Whe KIM ; Kyung Su JANG ; Jae Il LEE
The Journal of Korean Academy of Prosthodontics 2003;41(3):300-318
STATEMENT OF PROBLEM: The success of implants depends on intimate and direct contact of implant material on bone tissue and on functional relationship with soft tissue contact. Creation and maintenance of osseointegration depend on the understanding of the tissue's healing, repairing, and remodeling capacity and these capacities rely on cellular behavior. Altering the surface properties can modify cellular responses such as cell adhesion, cell motility, bone deposition. Therefore, various implant surface treatment methods are being developed for the improved bone cell responses. PURPOSE: The purpose of this study was to evaluate the responses of osteoblast-like cells to surface- modified titanium. MATERIALS AND METHODS: The experiment was composed of four groups. Group 1 represented the electropolished surface. Group 2 surfaces were machined surface. Group 3 and Group 4 were anodized surfaces. Group 3 had low roughness and Group 4 had high roughness. Physicochemical properties and microstructures of the d iscs were examined and the responses of osteoblast-like cells to the discs were investigated. The microtopography was observed by SEM. The roughness was measured by three-dimension roughness measuring system. The microstructure was analyzed by XRD, AES. To evaluate cell responses to modified titanium surfaces, osteoblasts isolated from calvaria of neonatal rat were cultured. Cell count, morphology, total protein measurement and alkaline phosphatase activities of the cultures were examined. RESULTS AND CONCLUSION: The results were as follows 1. The four groups showed specific microtopography respectively. Anodized group showed grain structure with micropores. 2. Surface roughness values were, from the lowest to the highest, electropolished group, machined group, low roughness anodized group, and high roughness anodized group. 3. Highly roughened anodized group was found to have increased surface oxide thickness and surface crystallinity. 4. The morphology of cells, flattened or spherical, were different from ach other. In the electropolished group and machined group, the cells were almost flattened. In two anodized groups, some cells were spherical and other cells were flattened. And the 14 day culture cells of all of the groups were nearly flattened due to confluency. 5. The number of attached cells was highest in low roughness anodized group. And the machined group had significantly lower cell count than any other groups(P<.05). 6. Total protein contents showed no difference among groups. 7. The level of alkaline phosphatase activities was higher in the anodized groups than electropolished and machined groups(P<.05).
Alkaline Phosphatase
;
Animals
;
Bone and Bones
;
Cell Adhesion
;
Cell Count
;
Cell Movement
;
Edible Grain
;
Crystallins
;
Osseointegration
;
Osteoblasts
;
Rats
;
Skull
;
Surface Properties
;
Titanium*
6.Percutaneous Vertebroplasty in Spinal Metastasis and Myeloma:25 Cases Experience.
Woo Min PARK ; Jee Soo JANG ; Chang Hun RHEE ; Ho Shin GWAK ; Seung Hoon LEE
Journal of Korean Neurosurgical Society 2000;29(11):1484-1490
No abstract available.
Neoplasm Metastasis*
;
Vertebroplasty*
7.Spontaneous Pulmonary Hemorrhage and Adult Respiratory Distress Syndrome after Thrombolytic Therapy for Acute Myocardial Infarction.
Jun Gu LEE ; Dong Hoon CHOI ; Seok Min KANG ; Yang Soo JANG
Korean Circulation Journal 1997;27(5):554-558
We report a cace of 69-year-old man who developed massive pulmonary hemorrhage and subsuquent adult respiratory distress syndrome following intravenous urokinase for acute myocardial infarction. Pulmonary hemorrhage is a rare but a potentially life-threatening complication after thrombolytic therapy and should be considered in the differential diagnosis of pulmonary infiltrates of falling hemoglobin after thrombolytic therapy for acute myocardial infarction with no obvious site of bleeding.
Adult*
;
Aged
;
Diagnosis, Differential
;
Hemorrhage*
;
Humans
;
Myocardial Infarction*
;
Respiratory Distress Syndrome, Adult*
;
Thrombolytic Therapy*
;
Urokinase-Type Plasminogen Activator
8.Ecthyma Gangrenosum in a Previously Healthy Adolescent.
Soo Min KIM ; In Hyuk CHUNG ; Gwang Cheon JANG ; Seum CHUNG ; Yeejeong KIM ; Nam Joon CHO
Korean Journal of Dermatology 2017;55(9):630-631
No abstract available.
Adolescent*
;
Ecthyma*
;
Humans
;
Pseudomonas aeruginosa
9.A Case of Liposarcoma of the Anterovesical Region..
Korean Journal of Urology 1976;17(3):213-215
Liposarcoma of the perivesical region is extremely rare and a few cases have been reported in the literature. A case of liposarcoma of the anterovesical region with involvement of the prostate occurred in a 7-year-old child was Presented. The literatures were briefly reviewed.
Child
;
Humans
;
Liposarcoma*
;
Prostate
10.A Case of Rectal Adenocarcinoma Metastatic.
Jong Min KIM ; Yean Sub JANG ; Tae Hoon CHO ; Eil Soo LEE
Korean Journal of Dermatology 1988;26(6):951-955
Adenocarcinoma metastatic to the skin usually originates in the lung, breast, large intestine or ovary. Cutaneous metastatic tumors from rectum or colon tend to appear in the abdominal or perineal area, but rarely appear in the perianal and genital skin. A 53-year-old female presented multiple nodules in and near the surgical scars of inguinal, pubie, vulvar, perianal areas and normal skin of left thigh two months after surgical removal of rectal adenocarcinoma. Biopsy specimens from the nodules of the perianal area and left thigh showed adenocarcinoma of well differentiated atruetures like the primary rectal carcinoma.
Adenocarcinoma*
;
Biopsy
;
Breast
;
Cicatrix
;
Colon
;
Female
;
Humans
;
Intestine, Large
;
Lung
;
Middle Aged
;
Ovary
;
Rectum
;
Skin
;
Thigh