1.The Changes of Lymphocytes and Subgroups for Postoperative Immunological Response in Gastrointestinal Carcinoma.
Sung Ock SUH ; Gil Soo SON ; Min Young CHO
Journal of the Korean Surgical Society 1999;57(2):217-223
BACKGROUND: Studies of immune response for cancer have demonstrated that the antitumor immune response plays a role in competing against the growth of cancer cells and is frequently altered in advanced cancer. METHODS: We evaluated the changes of peripheral blood lymphocytes and their subsets during preoperative and postoperative periods according to the time sequence of the postoperative condition in gastrointestinal carcinoma patients. Lymphocyte surface markers were determined in 39 stomach cancer patients and 33 colon cancer patients by using the indirect immunofluorescence technique with monoclonal antibodies. The patient's body weights, hemoglobin, hematocrits, total protein, and albumin were also measured preoperatively at and 1, 3, 6, 12, 18, and 24 months postoperatively. RESULTS: There were significant differences of clinico-laboratory findings between the preoperative and the postoperative periods except for hemoglobin, total protein, and albumin in postoperative course. The total leukocyte count significantly decreased from the postoperative 6th month. The lymphocyte count significantly increased from the postoperative 3rd month. The granulocytes decreased significantly in the postoperative 6th month. The T cells and B cells decreased in the postoperative 3rd month and 1st month, respectively. CD8 increased in the postoperative 3rd month and NK cells also increased in the postoperative 3rd, 6th and 24th months. Other peripheral lymphocytes and their subsets showed no significant differences. The changes in the lymphocyte subsets according to stage were not statistically significant (p<0.005). CONCLUSIONS: The postoperative changes in lymphocytes, granulocytes, and NK cells were significantly different compared with preoperative levels, but these results did not correlate with postoperative survival and recurrence rate because of the short postoperative follow-up periods.
Antibodies, Monoclonal
;
B-Lymphocytes
;
Body Weight
;
Colonic Neoplasms
;
Fluorescent Antibody Technique, Indirect
;
Follow-Up Studies
;
Granulocytes
;
Hematocrit
;
Humans
;
Killer Cells, Natural
;
Leukocyte Count
;
Lymphocyte Count
;
Lymphocyte Subsets
;
Lymphocytes*
;
Postoperative Period
;
Recurrence
;
Stomach Neoplasms
;
T-Lymphocytes
2.A Research Of Web-Based Real Time Automatic Fetal Monitoring System.
Min Soo HAN ; Sun KIM ; Young Gil KIM
Journal of Korean Society of Medical Informatics 2001;7(4):59-67
In this paper, using ultrasonic doppler signal, we composed fetal heart sound / fetal movement diagnosis and web-based database server/client environment. Detecting fetal heart rate and movement at the same time, for the data loss-caused from telemetering-protection and the high speed diagnosis, we made two signals mix and transmit. For the better communication between obstetrician and remote woman/fetus, we proposed database table that could reflect the whole information about remote fetus and its mom. And we supported HL-7 format so that we might be compatible with other vendor product and easy to access web-based hospital computerization system. Applying doctor to web-based high level biosignal analysis algorithm and expert system, we offered remote fetal biosignal and diagnostic assistant data inducing fast diagnosis. We made web-based fetal diagnostic system and improved web system compatibility, fast diagnosis and minimum of the rate of misdiagnosis.
Commerce
;
Diagnosis
;
Diagnostic Errors
;
Expert Systems
;
Female
;
Fetal Heart
;
Fetal Monitoring*
;
Fetal Movement
;
Fetus
;
Heart Rate, Fetal
;
Pregnancy
;
Ultrasonics
3.Histologic study of the autogenous auricular cartilage grafts in the rabbits femer
Gil Hyun SUNG ; Eun Cheol KIM ; Seung Ki MIN ; Dong Keun LEE ; Soo Name KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1993;15(1):49-61
No abstract available.
Ear Cartilage
;
Rabbits
;
Transplants
4.Effects of cryopreservative agents of the repair of the temporomandibular joint disk with allogeneic cartilage grafts in rabbits
Won Gyu KIM ; Soo Nam KIM ; Seung Ki MIN ; Gil Hyun SUNG ; Heak Do KEON
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1994;15(4):302-316
No abstract available.
Cartilage
;
Rabbits
;
Temporomandibular Joint Disc
;
Temporomandibular Joint
;
Transplants
5.A Case of Ticlopidine-induced Neutropeina Treated with rhG-CSF.
Sang Gil LEE ; Churl Woo AHN ; Hyun Soo KIM ; Sejoong RIM ; Seung Yeon CHO ; Yoo Hong MIN
Korean Circulation Journal 1998;28(1):118-122
There are many conditions which are associated with neutropenia, such as infections, chemical and physical agents, and hematopoietic diseases. But ticlopidine-induced neutropenis is rarely reported in Korea. We experienced a case of neutropenia which developed after approximately 1 month of ticlopidine administrarion to a stable angina pectories patient. A 59 year-old woman with stable angina pectoris was placed on ticlopidine. Forty days later, she was admitted for high fevers and shaking chills. On admission, leukocyte count was 900/mm (3) (neutrophil 0/mm (3)), hemoglobin was 11.8g/dl, and platelet count was 440.000/mm (3). After confirming ticlopidine-induced neutropenia by bone marrow aspiration and biopsy, we administated rhG-CSF (neutrogen (r), Choongwae. Co. Korea) at a dose of 3-5ug/kg daily. On the 25th day of treatment, leukocyte count reached 2,890/mm (3). She experienced no adverse effects of rhG-CSF treatment and recorved completely. We assume that the rapid recovery of granulocytes was attributable to rhG-CSF, and we suggest that rhG-CSF should be tried in a patients with ticlopidine-induced neutropenia with depletion of myeloid precursors in the hypocelluar bone marrow.
Angina, Stable
;
Biopsy
;
Bone Marrow
;
Chills
;
Female
;
Fever
;
Granulocytes
;
Humans
;
Korea
;
Leukocyte Count
;
Middle Aged
;
Neutropenia
;
Platelet Count
;
Ticlopidine
6.A Case of Primary Cutaneous Aspergillosis.
Min Soo LEE ; Ki Ho KIM ; Young Gil LEE
Korean Journal of Medical Mycology 1996;1(1):107-111
We report a case of primary cutaneous infection by Aspergillus fumigatus in a 19-year-old immunocompetent woman. She developed pruritic erythematous papules on the frontal and temporal scalp area and pubic area. The lesions rapidly progressed to ulcers with central black eschars and pus drainage. The diagnosis of Aspergillus fumigatus infection was established by the mycologic study of cultures from wound exudate and histopatholosic examination of the skin lesion. The skin lesions were improved after 5 weeks of antifungal therapy with oral itraconazole (200mg/day). Five months later, the skin lesions had healed, leaving some scar.
Aspergillosis*
;
Aspergillus fumigatus
;
Cicatrix
;
Diagnosis
;
Drainage
;
Exudates and Transudates
;
Female
;
Humans
;
Itraconazole
;
Scalp
;
Skin
;
Suppuration
;
Ulcer
;
Wounds and Injuries
;
Young Adult
7.Toxic Shock Syndrome after Mastopexy and Augmentation Mammoplasty with Saline-Filled Mammary Implant.
Se In JANG ; Min Sung SEO ; Young Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2001;28(5):581-584
Toxic shock syndrome is a rare but potentially fatal toxin-mediated febrile illness. Although classically associated with tampon use, it is now known that many nonmentral conditions are related to this syndrome. Serious morbidity and mortality can occur if this syndrome is not promptly recognized. Now, we are presenting that we have experienced a case of toxic shock syndrome patient who had been received augmentation mammoplasty using saline filled mammary implant and mastopexy concommittantly, and we managed the patient with massive hydration and systemic antibiotic therapy. Early recognition and aggressive management can decrease the overall morbidity and motality.
Female
;
Humans
;
Mammaplasty*
;
Mortality
;
Shock, Septic*
8.Transfusion - Associated Graft - Versus - Host Disease in Patients with Acute Leukemia.
Myung Soo CHA ; Kwang Hoon LEE ; Yoo Hong MIN ; Kwang Gil LEE
Korean Journal of Dermatology 1996;34(2):345-349
Graft-versus-host disease can develop in immunosuppressed individuals who receive blood product transfusions that contain imrnunocompetent lymphocytes. We report a case of transfusion-associated graft-versus-host disease(TA-GVHD) that developed in a patient with acute lymphocytic leukemia who were undergoing therapy. The groups at risk for development of TA-GVHD, the clinical presentation and course, and methods of diagnosis are summarized. Prevention of TA-CVHD is possible by irradiation of blood products given to patients at risk, but problems remain in determining the groups that warrant such measures. We should be aware of the risk of developing TA-GVHD after routine blood transfusion, especially in areas where the population's HLA types are rather homogeneous.
Blood Transfusion
;
Diagnosis
;
Graft vs Host Disease
;
Humans
;
Leukemia*
;
Lymphocytes
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Transplants*
9.Cementifying Fibroma of the Frontal Bone in Children: A Case Report.
Myung Ki KANG ; Sin Gil LEEM ; Jun Seep LEEM ; Seong Keun LEU ; Kyung Soo KIM ; Min Suk OH
Journal of Korean Neurosurgical Society 2000;29(4):559-563
No abstract available.
Child*
;
Fibroma*
;
Frontal Bone*
;
Humans
10.The Effect of Transconjunctival Lower Blepharoplasty Combined with Pinch Skin Excision Technique.
Mi Jung CHI ; Min Soo PARK ; Se Hyun BAEK
Journal of the Korean Ophthalmological Society 2007;48(6):755-760
PURPOSE: The aim of this study was to analyze the effects of transconjunctival lower blepharoplasty combined with the pinch skin excision technique. METHODS: This study followed 15 patients over a six-month period who had undergone transconjunctival lower blepharoplasty combined with the pinch skin excision technique. The follow-up period exceeded 6 months. After subconjunctival injection of local anesthetic, incisions of the conjunctiva and lower lid retractors were made. The exposed fat pads were excised by clamping, excising, and cauterizing the base of the pad. The conjunctiva was closed with a continuous 6-0 Vicryl suture. If there was mild skin excess, a pinch skin excision technique was used. RESULTS: There were no complications (i.e., lower eyelid retraction, ectropion, etc.). All 15 patients were satisfied with the final result. CONCLUSIONS: The transconjunctival lower blepharoplasty combined with the pinch skin excision technique in middle-aged patients with prominent lower eyelid fat and skin excess had lower complication rates and higher patient satisfaction than the transcutaneous approach.
Adipose Tissue
;
Blepharoplasty*
;
Conjunctiva
;
Constriction
;
Ectropion
;
Eyelids
;
Follow-Up Studies
;
Humans
;
Patient Satisfaction
;
Polyglactin 910
;
Skin*
;
Sutures