1.Basophil histamine releasability in children with atopic asthma.
Jung Yeon SHIM ; Won Chul BYUN ; Jeong Soo HONG ; Hee Bom MOON ; Soo Jong HONG
Journal of Asthma, Allergy and Clinical Immunology 1998;18(3):494-503
OBJECTIVE: To evaluate the basophil histamine releasability in response to IgE- and non- IgE-mediated stimuli in children with atopic asthma. Met: Basophil histamine releasability was measured in Dermatophagoides farinae (D. farinae)-sensitive atopic asthmatics, D.farinae-sensitive healthy atopics, non-atopic asthmatics, and healthy non-atopics. Basophils were stimulated with D.farinae, goat antihuman IgE antibody, formyl-Met-Leu-Phe(fMLP), and Calcium ionophore A23187. Histamine was measured by automated fluorometric technique. RESULTS: Sponianeous histamine release was higher in atopic asthmatics compared to healthy non-atopics. Histamine release by D.farinae and by anti-IgE antibody was higher in atopic asthmatics compared to the other groups. There was no difference in histamine release by fMLP among all groups. Histamine release by Calcium ionophore was higher in healthy atopics and non-atopic asthmatics compared to healthy non-atopics. The atopics showed correlation between histamine release by D.farinae, by anti-IgE antibody and total serum IgE levels. CONCLUSIONS: Spontaneous and IgE-mediated histamine release were related to the presence of both atopy and asthma, whereas non-IgE mediated histamine release was different depending on the stimuli.
Asthma*
;
Basophils*
;
Calcimycin
;
Calcium
;
Child*
;
Dermatophagoides farinae
;
Goats
;
Histamine Release
;
Histamine*
;
Humans
;
Immunoglobulin E
2.A Case of Zosteriform Pilar Leiomyoma.
Jeong Joon OH ; Jae Hong PARK ; Soo Hong KIM ; Eil Soo LEE
Annals of Dermatology 2003;15(3):128-131
Cutaneous pilar leiomyomas are benign, often painful, smooth muscle tumors that usually present as red-brown nodules. They are usually multiple and commonly found on the extensor aspects of the arm, trunk, and face. Multiple lesions may be grouped or widespread. They are rarely distributed in a linear fashion or seem to follow a dermatome. We report a 54-year-old woman with multiple pilar cutaneous leiomyomas distributed in a zosteriform pattern on her right trunk.
Arm
;
Female
;
Humans
;
Leiomyoma*
;
Middle Aged
;
Smooth Muscle Tumor
3.The Efficacy of Laparoscopic Burch Colposuspension for Female Stress Urinary Incontinence.
Jeong Hee HONG ; Seong Soo JEON ; Kyu Sung LEE
Korean Journal of Urology 2000;41(4):560-565
No abstract available.
Female*
;
Humans
;
Urinary Incontinence*
4.A Case of Autoinoculated Herpes Simplex.
Myung Soo SUH ; Jeong Hee HAHM ; Hong Il KOOK
Korean Journal of Dermatology 1977;15(3):365-367
A case of herpes simplex autoinoculated on the 1st interdigital web of right hand was reported, Herpes labialis characterized by confluent rice sized vesicular eruptions had developed on the midportion of upper lip. After 3 days, typical herpetic lesion occurred on the 1st interdigital web of right hand. We reviewed briefly the recent literatures.
Hand
;
Herpes Labialis
;
Herpes Simplex*
;
Lip
5.Two Cases of Cutaneous Cytomegalovirus Infection in Immunocompromised Patients.
Jae Hong PARK ; Jeong Joon OH ; Eil Soo LEE
Annals of Dermatology 2004;16(2):67-70
Cytomegalovirus (CMV) is a major cause of morbidity and mortality in immunocompromised patients. CMV can cause pneumonia, retinitis, gastrointestinal ulcers, and widely disseminated disease, but cutaneous CMV is rare. We report two cases of cutaneous CMV infection presenting as perianal ulcers. A 54 year-old male who had liver transplantation and a 72-year-old male, who was treated with chemotherapy for angioimmunoblastic T-cell lymphoma, presented with perianal ulcers and had systemic symptoms of CMV infection with CMV antigenemia. They had multiple ulcerations with erythematous bases on the perianal area, and histopathologic examinations showed large atypical cytomegalic cells in the dermis, and immunohistochemical stains, with the anti-CMV antibody showed positive reactions.
Aged
;
Coloring Agents
;
Cytomegalovirus Infections*
;
Cytomegalovirus*
;
Dermis
;
Drug Therapy
;
Humans
;
Immunocompromised Host*
;
Liver Transplantation
;
Lymphoma, T-Cell
;
Male
;
Mortality
;
Pneumonia
;
Retinitis
;
Ulcer
6.Two Cases of Xeroderma Pigmentosum.
Myoung Soo SUH ; Jeong Hee HAHM ; Hong Il KOOK
Korean Journal of Dermatology 1978;16(3):261-271
Xeroderma pigmentosum is a hereditary disorder characterized by the early development of pigmentary chnges, atropht, keratoses, and carcinoma, predominantly light exposed area skin.Two cases of xeroderma pigmentosum complicated by basal cell Ca. were presented. The one was 15 years old male who had been suffered from pea to walnut sized multiple tumors and ulcers on the face with scattered brownish macuIes on the eun exposed area since about 9 years old of his age. The other was 22 years old maIe who had been suffered from the same skin lesions as the former on the face, neck and dorsum of hands. In both cases skin lesions aggravated during each summer seasons and there were on history of convulsions and other neurological symptoms Histopathological findings of tumors on both cases revealed typical findings of basal cell Ca.
Adolescent
;
Child
;
Hand
;
Humans
;
Ichthyosis*
;
Juglans
;
Keratosis
;
Male
;
Neck
;
Peas
;
Seasons
;
Seizures
;
Skin
;
Ulcer
;
Xeroderma Pigmentosum*
;
Young Adult
7.Clinical study of press-fit type cementless total hip replacement arthroplasty.
Keun Woo KIM ; Yoon Soo PARK ; Kee Jeong HONG
The Journal of the Korean Orthopaedic Association 1991;26(3):877-885
No abstract available.
Arthroplasty*
;
Arthroplasty, Replacement, Hip*
8.Clinical application of hydroxyapatite(surgibone(r)).
Jung Soo HONG ; Jeong Chul KIM ; Jae Ho JEONG ; Dong Bo SUH ; Jung Hyun SEUL
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(2):333-342
No abstract available.
9.Unilateral Congenital Diaphragmatic Eventration Mimicking Congenital Diaphragmatic Hernia.
Jeong In YANG ; Kie Suk OH ; Haeng Soo KIM ; June Seo LEE ; Jeong HONG
Korean Journal of Obstetrics and Gynecology 1999;42(1):171-174
Congenital diaphragmatic eventration is an abnormal elevation of the diaphragm as a result of developmental failure of muscular fibers during the fetal period. Mediastinal shift to the contralateral side may cause significant compression of the affected chest contents resulting in compromised pulmonary function especially when bilaterally involved. The differentiation between congenital diaphragmatic eventration and diaphragmatic hemia is very difficult but eventration has a better perinatal outcome compared to diaphragmatic hernia. We report a case of congenital diaphragmatic eventration on left side with good perinatal outcome after plication in which the initial prenatal diagnosis of diaphragmatic hernia was made by prenatal ultrasonography.
Diaphragm
;
Diaphragmatic Eventration*
;
Hernia, Diaphragmatic*
;
Prenatal Diagnosis
;
Thorax
;
Ultrasonography
;
Ultrasonography, Prenatal
10.Association of Dopamine D4 Receptor(DRD4) Gene Polymorphism with Korean Schizophrenic Patients.
Hong Seock LEE ; Min Soo LEE ; Deock Jeong HAN ; Heon Jeong LEE
Journal of the Korean Society of Biological Psychiatry 2000;7(2):152-158
BACKGROUND: No association between schizophrenia and dopamine D4 receptor polymorphisms have been reported. Despite these results, it is premature to exclude the association. It has been suggested that the susceptibility to develop schizophrenia could result from variation at a number loci which may interact or co-act with each other. Therefore, we investigated a possible assoication of combinations of exon III 48bp polymorphism [D4E3] and exon I 12bp polymorphism of the DRD4 gene [D4E1] with schizophrenia. METHOD: 207 unrelated Korean schizophrenic patients and 191 healthy controls wee recruited. DRD4 genotype was established using the polymerase chain reaction. Statistical analysis consisted of chi2 tests for Hardy-Weinberg proportions and genotypic and allelic frequencies in the patients and control groups. RESULT: There were no statistically significant differences in the each polymorphisms between schizophrenics and controls. And all genotype frequencies were within Hardy-Weinberg expectations. When the combinations of the polymorphism in schizophrenia and controls were compared, however, there were significant differences at A1A2*2/4 in the distributions of the combinations of D4E1 and D4E3(p<0.01). CONCLUSION: These findings suggest that the certain combination of D4E1 and D4E3 (A1A2*2/4) has the protective role to a susceptibility for schizophrenia.
Dopamine*
;
Exons
;
Genotype
;
Humans
;
Polymerase Chain Reaction
;
Receptors, Dopamine D4
;
Schizophrenia