BACKGROUND: Korea university Gyro Hospital has run the KULAB system successfully since 1985, the increasing amount of hospital information made us the need for new system with larger capacity. We began to transform the KULAB, LIS only to the wly developed KUMNET-LAB, OCS system and we report our experience. METHODS: We used 5290 (Sequent, USA) with main memory of 128 megabyte and hard disk of 6.3 gigabyte as main completer, ORAGLE 7.2 (Oracle, USA) as database, fifteen 486 PCs, eight printers and seven barcode printers in the laboratory. A LAN was built. Pro-C was used in interface between the outpatient cashier and LIS. The Power builder (PentaKorea, USA) and Forms (Oracle, USA) and visual basic were used in interface between LIS and autoanalyzer. It took one month to analyse laboratory work flow and 2 months to programming by 2 programmers from the commercial vendor, ICM (Information & Communication Management Inc.). All laboratorian had taken part in job analyses and evaluations. RESULTS: Our laboratory information system was successfuly implemented without any major problem. The specimen type and emergency status were added to the test code. And the field indicating the sequential position on screen was added to the master to control the position of the test codes on screen. Bar code system was introduced to ample identification as well as specifically assigned specimen number. CONCLUSION: The KULAB system had been used from 1985 through 1995 was successfully transfered to the more efficient new LIS, KUMNET-LAB which is one of the basis of the OCS system (KUMNET).
Automatic Data Processing ; Clinical Laboratory Information Systems ; Commerce ; Emergencies ; Humans ; Korea* ; Local Area Networks ; Memory ; Outpatients ; Workflow

BACKGROUND: Transforming growth factor-beta(TGF-beta) has multiple regulatory effects on cells of the immune system, and it has been suggested that differentiation of lymphoid cells is influenced by low concentra tions of this cytokine. OBJECTIVES: The aim or this study was to investigate the role of TGF-beta in regulation of T cell growth and differentiation, and to compare this effect with that of other cell signals known to be important in T cell ontogeny. METHODS: We used the CTLL-2 cell line in the presence of IL-2. Surface phenotype expression was analysed to see whether these cells could be switched to the other subtype of cells. RESULT: Treatment of CTLL-2 cells with TGF-beta resulted in dose dependent growth inhibition and morphological changes. Curing routine passage, less than 5% of cells were CD8alpha positive, whereas 38% of cells expressed CD8alpha when treated with IL-2 plus TGF-beta. However, TPA plus calcium ionophore, IFN-gamma, or TNF-alpha caused no significant changes in the proportion of CD8 cells. CONCLUSION: Our results show that this experiment can be a useful model for investigating CD8 precursor potentials in populations of CD4-CD8-(double negative) cells, and such a model may offer a way to study the molecular regulation of CD8 gene expression.
Calcium ; Cell Line* ; Gene Expression ; Immune System ; Interleukin-2 ; Lymphocytes ; Phenotype ; Transforming Growth Factor beta ; Tumor Necrosis Factor-alpha

No abstract available.
Asthma*

Pulmonary endometriosis is a rare disease which is characterized by hemoptysis during menstruation (catamenial hemoptysis). We report a case of pulmonary endometriosis in a 33-year-old housewife. She has had regular menses with moderate flow and minimal dysmenorrhea. She had undergone curettage in May 1995 for artificial abortion. In July 1995, she experienced the first episode of hemoptysis. A chest CT scan revealed a 2.0 1.0 cm sized ill-defined soft tissue density in the periphery of anterior segment of the left upper lobe with a surrounding irregular ground-glass opacity. A left upper lobectomy was done under the diagnosis of pulmonary endometriosis. Cut section of the resected lung showed a round red-brownish solid lesion, measuring 2.0x1.0cm in cross. Microscopically a focus of the endometrial tissue, which was composed of endometrial glands and stroma, was found in the lung parenchyme and many hemosiderin laden macrophages were seen in the surrounding alveoli. The postoperative course was favorable with no further episodes of hemoptysis.
Adult ; Curettage ; Diagnosis ; Dysmenorrhea ; Endometriosis* ; Female ; Hemoptysis ; Hemosiderin ; Humans ; Lung ; Macrophages ; Menstruation ; Rare Diseases ; Tomography, X-Ray Computed

No abstract available.

No abstract available.
Dystocia* ; Female ; Pregnancy ; Shoulder*

No abstract available.
Animals ; Biogenic Amines* ; Brain* ; Electroshock* ; Rats*

No abstract available.
Urticaria*

The dithiocarbsmates are commonly used worldwide as an agricultural fungicide because they are inexpensive and known to be highly effective, A 37 year old male farmer visited our department because of skin rashes on the face, neck and both handa for three years. Because the patch test results revealed a strong positive reaction to dithiocarbamates, and the irritant reaction to orthodichlorobenzen and the biopsy specimen taken from the lesion of dorsum of hand showed the findings of allergic contact dermatitis, the diagnosis of allergic contact dermatitis due to dithiocarbamate was made. The skin lesions were cleared after avoicing the causative agent along with consertatve treatment. There was no relapse during the one year follow up period.
Adult ; Biopsy ; Dermatitis, Allergic Contact* ; Diagnosis ; Exanthema ; Follow-Up Studies ; Hand ; Humans ; Male ; Neck ; Patch Tests ; Recurrence ; Skin

PURPOSE: We evaluated the diagnostic accuracy and clinical usefulness of fluoroscopy-guided bone biopsy. MATERIALS AND METHODS: A total of 31 patients with various skeletal lesions underwent fluoroscopy-guided bone biopsies. The targets were long bones in 16 cases, pelvic bones in 7 cases, spines in 6 cases, and ribs in the rest 2 cases. RESULTS: The overall accuracy was 71%(22/31). The accuracy was 100% in case of primary sarcoma and multiple myeloma. But it was low in malignant lymphoma(1/4), malignant fibrous histiocytoma(0/1), and nonossifying fibroma(0/1). CONCLUSION: Percutaneous fluoroscopy-guided bone biopsy is a simple, safe, not-expensive, and rather accurate diagnostic procedure in evaluation of bone tumors. In addition to that, it is useful in the managment planning and fllow-up of the patients.
Biopsy* ; Humans ; Multiple Myeloma ; Pelvic Bones ; Ribs ; Sarcoma ; Spine