1.A fruitful case of pregnancy by simplified GIFT procedure with tuboplasty.
Young Soo CHOE ; Tae Won SUNWOO ; Joon Yong HUR ; Kap Soon JU ; Soo Yong CHOUGH
Korean Journal of Obstetrics and Gynecology 1993;36(7):2067-2071
No abstract available.
Fruit*
;
Pregnancy*
2.Diagnostic and Prognostic Value of Umbilical and Descending Thoracic Aorta Velocimetry.
Jae Kwan LEE ; Jun Young HUR ; Ho Suk SAW ; Yong Kyun PARK ; Soo Yong CHOUGH
Korean Journal of Obstetrics and Gynecology 1999;42(10):2341-2347
OBJECTIVES: Early diagnosis of intrauterine growth retardation is important to ensure optimal monitoring and delivery with the introduction of real-time and Doppler ultrasound systems, a noninvasive method of measuring human fetal blood flow has become available. The aim of this study is to compare blood flow velocity waveforms at the fetal descending aorta and umbilical artery in normal and in patients with pregnancy induced hypertension. METHODS: Using a combination of linear array real-time and pulsed Doppler ultrasound, blood flow velocity measurements were carried out at the fetal descending aorta and umbilical artery in 35 normal pregnancies and 18 cases of pregnancy induced hypertensive patients. RESULTS: The mean systolic/diastolic ratio of umbilical artery and aorta was significantly higher in PIH patients than in normal pregnancies(3.8 +/- 0.81 versus 2.97 +/- 0.52, p<0.05) and to predict perinatal morbidity, umbilical velocimetry is more sensitive than that of descending thoracic aorta. CONCLUSION: This study suggests that umbilical artery velocimetry could be used as a marker to predict adverse perinatal outcome.
Aorta
;
Aorta, Thoracic*
;
Blood Flow Velocity
;
Early Diagnosis
;
Female
;
Fetal Blood
;
Fetal Growth Retardation
;
Humans
;
Hypertension, Pregnancy-Induced
;
Pregnancy
;
Rheology*
;
Ultrasonography
;
Umbilical Arteries
3.Hybrid Capture System HPV DNA Test as a Screening Tool of Cervical Cancer.
Jung Ho SHIN ; Jae Kwan LEE ; Soo Yong CHOUGH ; Jun Young HUR ; Yong Kyun PARK ; Ho Suk SAW
Korean Journal of Gynecologic Oncology and Colposcopy 2001;12(1):31-38
OBJECTIVE: Although the use of cytology in screening has reduced morbidity and mortality from invasive cervical cancer, there has been limitation because of the low sensitivity and high false negative rate in the detection of preclinical or clinical disease of the cervix. This study was performed to explore the usefulness of Hybrid Capture System HPV DNA test as a diagnostic method of the cervical cancer. METHODS: Cervical cytology and Hybrid Capture System 1 (HCS1) HPV DNA test were performed in 1,023 women who visited Gynecologic Oncology Clinic in Guro Hospital, Korea University Medical Center. HPV DNA were retested by HCS1, HCS2 and Polymerase Chain Reaction(PCR), in randomly selected 200 women to compare these DNA tests. RESULTS: While the sensitivity and specificity of cervical cytology in detection of cervical lesion were 71.2% and 89.5%, those of HCS1 HPV DNA test were 63.0% and 86.9% respectively. There was significant difference in detection of cervical precancerous lesions between HCS1 and HCS2 (P<0.05), but not between HCS2 and PCR (P=0.14). And the sensitivity and specificity were improved with combining cytology and HCS1 HPV DNA test(82.2%, 86.9%~). CONCLUSION: HCS HPV DNA test may be considered as a useful adjunctive test with cervical cytology in cervical cancer screening.
Academic Medical Centers
;
Cervix Uteri
;
DNA
;
Female
;
Human Papillomavirus DNA Tests*
;
Humans
;
Korea
;
Mass Screening*
;
Mortality
;
Polymerase Chain Reaction
;
Sensitivity and Specificity
;
Uterine Cervical Neoplasms*
4.Four cases of unruptured rudimentary horn pregnancy.
Tae Won SUNWOO ; Young Soo CHOI ; Joon Yong HUR ; Ho Seok SUH ; Yong Gyun PARK ; Gap Soon JU ; Soo Yong CHOUGH
Korean Journal of Obstetrics and Gynecology 1992;35(12):1831-1838
No abstract available.
Animals
;
Horns*
;
Pregnancy*
5.Unscheduled vaginal bleeding and associated gynecologic care in postmenopausal women using hormone replacement therapy: comparison of cyclic versus continuous combined regimen.
Mi Jung LEE ; Jeong A NA ; In Ho KIM ; Jun Young HUR ; Yong Kyun PARK ; Kap Soon JU ; Ho Suk SAW ; Soo Yong CHOUGH
Korean Journal of Obstetrics and Gynecology 2000;43(2):216-220
OBJECTIVE: To measure gynecologic resources required to care for women who have unscheduled vaginal bleeding while using hormone replacement therapy. MATERIALS AND METHODS: Between January 1996 to December 1998, women presenting with abnormal withdrawal bleeding on HRT were identified and associated clinic visits and gynecologic procedures were recorded during a mean follow-up of 2 years. RESULTS: Among women using cyclic HRT, 28.9% had> OR =1 visit for unscheduled vaginal bleeding 8.7% had> OR =1 endometrial biopsy. Among women using continuous combined HRT, 19.3% had> OR =1 visit for unscheduled vaginal bleeding and 6.4% had> OR =1 endometrial biopsy. The gynecologic procedures used in women using cyclic HRT were 20% of reassurance, 50% of ultrasonograpy, 30% of endometrial biopsy and in women using continuous combined HRT were 50% of reassurance, 16.6% of ultrasonograpy, 33.3% of endometrial biopsy. The results of endometrial biopsy were reported all the benign condition. CONCLUSION(S): Unscheduled vaginal bleeding markedly decreased after 12 months of therapy in women using continuous combined HRT but did not decline among those using cyclic HRT.
Ambulatory Care
;
Biopsy
;
Female
;
Follow-Up Studies
;
Hemorrhage
;
Hormone Replacement Therapy*
;
Humans
;
Uterine Hemorrhage*
6.A Case of Intrauterine Pregnancy after Laparoscopic Bilateral Uterine Artery Ligation for Treatment Uterine Myoma .
Joo Young MIN ; Seung Hun SONG ; Kyeung Ju LEE ; Jae Kwan LEE ; Min Jung OH ; Ho Suk SAW ; Yong Kyun PARK ; Soo Young CHOUGH ; Jun Young HUR
Korean Journal of Obstetrics and Gynecology 2003;46(6):1250-1255
Uterine artery ligation or embolization is a minimally invasive alternative for treatment of symptomatic leiomyoma. However, the experience with pregnancy management and outcome after ablating uterine blood flow is still unknown. We have recently experienced a case of a woman who had two successful spontaneous intrauterine pregnancies after laparoscopic uterine artery ligation to treat uterine myoma for dysmenorrhea and menometrorrhagia.
Dysmenorrhea
;
Female
;
Humans
;
Leiomyoma*
;
Ligation*
;
Myoma
;
Pregnancy*
;
Uterine Artery*
7.The Effects of Conjugated Equine Estrogens Plus Dydrogesterone on Lipid and Bone Metabolism inPostmenopausal Women.
Soo Yong CHOUGH ; Jae Kwan LEE ; Jun Young HUR ; Ho Sawk SAW ; Yong Kyun PARK ; Kap Soon JU ; In Soo IM ; Kap No LEE
Korean Journal of Obstetrics and Gynecology 1997;40(5):1037-1043
The addition of a monthly course of progesterone decrease the incidence of endometrialhyperplasia and endometrial carcinoma. The progesterones used in hormonal replacementtherapy(HRT) differ markedly in their progesteronic, androgenic and even estrogenicactivities. These characteristics may influence both symptomatic and metabolic side effects.The purpose of this study was to examine effect of bone and lipid metabolism inpostmenopausal women treated with conjugated equine estrogens plus dydrogesterone.A total 131 postmenopausal women(surgical menopause=95, natural menopause=36)and not-treated postmenopausal women(control=22) were invited to participate in thisstudy. Patients were divided into groups which had received conjugated equine estrogen(CEE)0.625 mg/day 21-day-cycle each month(n=20), CEE 0.625 mg/day plus Dydrogesterone 10mg/day 10-day-cycle each month(n=111), and no treatment control group(n=20).Serum lipid and lipoprotein(Triglyceride, Total cholesterol, High density lipoprotein, Lowdensity lipoprotein) and serum osteocalcin, urinary Deoxypyridinoline were examined in allpatients.There were no significant differences in bone and lipid metabolism between CEE andCEE plus Dydrogesterone groups.In conclusion, Dydrogesterone may be used safely in postmenopausal women withoutMetabolic side effect.
Cholesterol
;
Dydrogesterone*
;
Endometrial Neoplasms
;
Estrogens, Conjugated (USP)*
;
Female
;
Hormone Replacement Therapy
;
Humans
;
Incidence
;
Lipid Metabolism
;
Lipoproteins
;
Metabolism*
;
Osteocalcin
;
Progesterone
8.Analysis of 1,046 Cases of Midtrimester Genetic Amniocentesis.
Min Jeong OH ; Jun Young HUR ; Ho Suk SUH ; Yong Gyun PARK ; Soo Yong CHOUGH ; Sun Hwa PARK ; Kap Soon JU
Korean Journal of Obstetrics and Gynecology 1997;40(6):1244-1251
Prenatal diagnosis of genetic disorders is now an established part of routine antenatalcare. This is a study of our experience with 1,046 cases that have been undergone amniocentesisat the Guro Hospital of the Korea University Medical School from October 1983 toJune 1996. Advanced maternal age was by far the most common indication of amniocentesis.Chromosomal aberrations were diagnosed in 15 cases(1.4%) of which numerical aberrationwas 9 cases(60/0%) and structural aberration was 6 cases(40.0%). Autosomal aberrationwas observed in fourteen cases(93.3%) and sex chromosomal aberration was observedin one case(6.7%). Among the 14 autosomal aberrations, trisomy 21 was most common,being 5 cases, and one case of trisomy 13 and another case of trisomy 18 was found respectively.The others were 4 cases of translocation, one case of inversion and another case ofisochromosome. Sex chomosomal aberration case was only one and it was a Klinefeltersyndrome.
Amniocentesis*
;
Chromosome Aberrations
;
Down Syndrome
;
Female
;
Humans
;
Korea
;
Maternal Age
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Prenatal Diagnosis
;
Schools, Medical
;
Trisomy
9.A Case of Clear Cell Carcinoma of Endometrium.
Hwa Kyung JUNG ; Hyun Jun JEE ; Min Jeong OH ; Ho Suk SAW ; Yong Kyun PARK ; Soo Yong CHOUGH ; Jun Young HUR
Korean Journal of Obstetrics and Gynecology 2002;45(10):1852-1855
Clear cell carcinoma of the endometrium is a relatively rare malignancy that is considered to be one of the most aggressive types of endometrial carcinoma. It is an infrequent variant sharing a common Mullerian origin, accounting for 1 to 5 percent of all endometrial cancers. Histologically, these tumors consists of hobnail cells which have translucent or slightly eosinophilic cytoplasm and protrude to lumen of gland. These tumors occur predominantly in postmenopausal women and carry a relatively unfavorable prognosis comparing with other histologic types of endometrial cancer. We experienced a case of clear cell carcinoma of endometrium in a 81-year old women and this case is presented with a brief review of the literaturs.
Aged, 80 and over
;
Cytoplasm
;
Endometrial Neoplasms*
;
Endometrium
;
Eosinophils
;
Female
;
Humans
;
Prognosis
10.Amifostine Pretreatment for Protection against Cisplatin-based Combination Chemotherapy in Gynecologic Cancer Patients.
Lynn Hwa LEE ; Hyun Jun JEE ; Hwa Kyung JUNG ; Yua JUNG ; Jung Ho SHIN ; Hee Suk OH ; Yong Kyun PARK ; Jun Young HUR ; Soo Yong CHOUGH ; Ho Suk SAW
Korean Journal of Obstetrics and Gynecology 2001;44(11):1961-1967
OBJECTIVE: Amifostine (Ethyol(R)), an organic thiophosphate, has shown the ability to protect normal, but not neoplastic, tissues from the damaging effects of chemotherapy and radiotherapy in various kinds of cancers. This study was designed to determine ifostine could reduce the serious hematologic and nephrologic toxicities associated with cisplatin based combination chemotherapy in gynecologic cancer patients. PATIENTS AND METHODS: Forty patients who received cisplatin-based combination chemotherapy were randomized into two groups. They received chemotherapy with or without pretreatment of amifostine before each course. The occurrence of hematologic and renal toxicities were evaluated. Stastical analysis was done by independent t-test and Chi-square test. RESULTS: Hematologic toxicity was evaluated with nadir count of neutrophil and platelet. The nadir count of neutrophil was 2034.2+/-1199.20/microliter in group with pretreatment using amifostine vs 1070.85+/-472.66/microliter in control group (p<0.01). Platelet count was not statistically different. (p<0.16) Grade 3 neutropenia was observed in nine (45%) patients in pretreatment group vs four (20%) patients with control group (p<0.09). Grade 4 neutropenia occurred in one patient only in control group. Renal toxicity was evaluated by serum creatinine and creatinine clearance. Protracted serum creatinine elevation was not significant in both groups. (p<0.14) Reduction of creatinine clearance was less in patients with pretreatment (p<0.01). There were no significant side reactions in subjects using amifostine. CONCLUSION: Pretreatment with amifostine reduces the neutropenia and nephrotoxicity associated with cisplatin-based combination chemotherapy with gynecologic cancer patients.
Amifostine*
;
Blood Platelets
;
Cisplatin
;
Creatinine
;
Drug Therapy
;
Drug Therapy, Combination*
;
Humans
;
Neutropenia
;
Neutrophils
;
Platelet Count
;
Radiotherapy