1.A case of congenital tricuspid stenosis.
Chan Uhng JOO ; Soo Young CHO ; Soo Chul CHO
Journal of the Korean Pediatric Society 1993;36(5):733-736
Congenital tricuspid stenosis is an uncommon congenital heart anomaly. Tricuspid stenosis is usually associated with other anomalies, most commonly severe pulmonary stenosis or atresia with secondary hypoplasia of the right ventricle. Clinically it may be difficult to distinguish from tricuspid atresia. A case of congenital tricuspid stenosis in a 32 day-old-girl is presented. The patient had cyanosis and dyspnea. Echocardiographic study revealed tricuspid stenosis with right ventricular hypoplasia, atrial septal defect and pulmonary stenosis.
Constriction, Pathologic*
;
Cyanosis
;
Dyspnea
;
Echocardiography
;
Heart
;
Heart Defects, Congenital
;
Heart Septal Defects, Atrial
;
Heart Ventricles
;
Humans
;
Pulmonary Valve Stenosis
;
Tricuspid Atresia
2.Cystic disease of pancreas.
Journal of the Korean Surgical Society 1992;42(4):507-513
No abstract available.
Pancreas*
3.A Study on the Renal Function in Neonates and Children.
In Soo CHOI ; Young Sook KIM ; Soo Chul CHO ; Jung Soo KIM ; Kyung Woo CHO
Journal of the Korean Pediatric Society 1983;26(8):744-750
No abstract available.
Child*
;
Humans
;
Infant, Newborn*
4.Changes of beta-lactoglobulin Specific Immunoglobulins According to the Age and the Onset of Cow's Milk Feeding.
Jong San LEE ; Soo Young CHO ; Pyoung Han HWANG ; Soo Cheol CHO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1990;33(12):1639-1646
No abstract available.
Immunoglobulins*
;
Lactoglobulins*
;
Milk*
5.The effect of transforming growth factor-beta on the expression of CD8 in the CTLL-2 cell line.
Soo Young PARK ; Yoon Hae CHANG ; Young Joo CHO
Journal of Asthma, Allergy and Clinical Immunology 2000;20(1):92-98
BACKGROUND: Transforming growth factor-beta(TGF-beta) has multiple regulatory effects on cells of the immune system, and it has been suggested that differentiation of lymphoid cells is influenced by low concentra tions of this cytokine. OBJECTIVES: The aim or this study was to investigate the role of TGF-beta in regulation of T cell growth and differentiation, and to compare this effect with that of other cell signals known to be important in T cell ontogeny. METHODS: We used the CTLL-2 cell line in the presence of IL-2. Surface phenotype expression was analysed to see whether these cells could be switched to the other subtype of cells. RESULT: Treatment of CTLL-2 cells with TGF-beta resulted in dose dependent growth inhibition and morphological changes. Curing routine passage, less than 5% of cells were CD8alpha positive, whereas 38% of cells expressed CD8alpha when treated with IL-2 plus TGF-beta. However, TPA plus calcium ionophore, IFN-gamma, or TNF-alpha caused no significant changes in the proportion of CD8 cells. CONCLUSION: Our results show that this experiment can be a useful model for investigating CD8 precursor potentials in populations of CD4-CD8-(double negative) cells, and such a model may offer a way to study the molecular regulation of CD8 gene expression.
Calcium
;
Cell Line*
;
Gene Expression
;
Immune System
;
Interleukin-2
;
Lymphocytes
;
Phenotype
;
Transforming Growth Factor beta
;
Tumor Necrosis Factor-alpha
6.The Adequate Extent of Thoracic Sympathectomy for Essential Palmar Hyperhidrosis.
Young Sul YOON ; Young Soo KIM ; Yong Eun CHO ; Kyung Gi CHO
Journal of Korean Neurosurgical Society 1998;27(4):481-487
Essential palmar hyperhidrosis is a disease characterized by excessive perspiration on the palms and hands due to the hyperaction of sympathetic nervous discharge. In severe cases, excessive sweating is seen on the face, axilla, trunk, and soles. Several therapeutic modalities were applied but surgical resection of the sympathetic ganglion is the only curative method. Numerous open surgeries of the thoracic sympathetic ganglia for the treatment of palmar hyperhidrosis have been advocated, but they have also produced several complications. A new therapeutic technique for this disorder has been introduced by combining a thoracoscope and video system. Nowadays, thoracoscopic transthoracic sympathectomy is accepted as the treatment of choice for essential palmar hyperhidrosis. This technique is safe and easy. It also reduces the operating time and admission period. It has also very few complications. Compensatory hyperhidrosis on the trunk, back, and thigh, etc. is commonly an unwanted and unsolved complication after thoracic sympathectomy. Through my experience of thoracic sympathectomy, I thought that the incidence of compensatory hyperhidrosis was closely related to the extent of thoracic sympathectomy. So I restricted the extent of thoracic sympathectomy as a T2 sympathetic ganglion from September 1995. From Mar., 1989 To Aug., 1995, T2, T3 sympathetic ganglionectomies were performed for palmar hyperhidrosis patients and from Sept. 1995 T2 sympathetic ganglionectomies were performed. Using questionnaires, I compared these 2 groups. The results of this study are summarized as follows; 1) Using thoracoscopic transthoracic sympathectomy, operating time, admission period and complications could be reduced. 2) The risk of bleeding during the operation(especially bleeding from the hemiazygous vein) could be reduced in the T2 sympathectomy group. 3) The treatment effect of T2 sympathectomy is no different from T2, T3 sympathectomy for essential palmar hyperhidrosis. 4) The incidence of compensatory hyperhidrosis is less in the T2 sympathectomy group than in the T2, T3 sympathectomy group. From the above results, I concluded thoracoscopic transthoracic sympathectomy is the treatment of choice for essential palmar hyperhidrosis and the adequate extent for sympathectomy is T2 sympathetic ganglion.
Axilla
;
Ganglia, Sympathetic
;
Ganglionectomy
;
Hand
;
Hemorrhage
;
Humans
;
Hyperhidrosis*
;
Incidence
;
Surveys and Questionnaires
;
Sweat
;
Sweating
;
Sympathectomy*
;
Thigh
;
Thoracoscopes
7.A Case of Wiskott-Aldrich Syndrome.
Byoung Geun LEE ; Soo Hee CHANG ; Soo Young CHO ; Pyoung Han HWANG ; Jung Soo KIM
Journal of the Korean Pediatric Society 1994;37(11):1615-1619
Wiskott-Aldrich Syndrome is an X-linked disorder characterized by recurrent infection, thrombocypenia and eczema. Various defects in cell-mediated immunity and deficient antibody reponse to carbohydrate antigens have been described. We experienced a case of Wiskott-Aldrich Syndrome of 28 months old male patient. He has been suffered from multiple petechiae with bleeding, recurrent pyogenic infections and generalized eczema since 3 months of age. Immunological abnormalities are as follows: 1) Serum IgM was gradually decreased, while IgA and IgE were increased. 2) Antibody response against polysaccharide antigen (PRP) was not observed after 3 times of PRPT immunization. 3) CD4/CD8 ratio was reversed (0.6). 4) Proliferative response of mononuclear cells was significantly reduced, and CMI skin test also showed negative results. A brief review of literature was made.
Antibody Formation
;
Child, Preschool
;
Eczema
;
Hemorrhage
;
Humans
;
Immunity, Cellular
;
Immunization
;
Immunoglobulin A
;
Immunoglobulin E
;
Immunoglobulin M
;
Male
;
Purpura
;
Skin Tests
;
Wiskott-Aldrich Syndrome*
8.Digital Infrared Thermographic Imaging(D.I.T.I.) in Herniated Lumbar Disc Patients.
Young Soo KIM ; Yong Eun CHO ; Seong Hoon OH
Journal of Korean Neurosurgical Society 1990;19(10-12):1303-1313
Thermography is a sensitive and reliable method for diagnosis of radiculopathy. Skin temperature alterations of the involved dermatome named thermatone are diagnostic for sensory root involvement in radiculopathy which can be demonstrated by thermography. Digital infrared thermographic imaging system using computer is development and could measure thermal difference more exactly without hazards or discomforts to patient. Authors present 186 cases of thermographic evaluation in herniated lumbar disc disease by digital infrared thermographic imging system and the results are evaluated with literature review.
Diagnosis
;
Humans
;
Radiculopathy
;
Skin Temperature
;
Thermography
9.Research on the frequency of Terry's nail in the medical inpatients with chronic illnesses.
Kwang Young PARK ; Sang Won KIM ; Jong Soo CHO
Korean Journal of Dermatology 1992;30(6):864-870
Terrys nail(TN) might be causally associated with cirrhosis or other disorders, but his criteria have been proved to be inadequate reflection of systcmic disorders. Modified criteria of Holzberg and Walker were introduced in TN examination in 1984. Using these criteria, fingernails were studied in 444 medical inpatients with chronic systemic diseases at Taegu Catholic Hospital from March 1991 to March 1992. There were 136(30.6%) patients with TN and 308(69.4%) patients without TN, respectively. Ninety-three patients with TN showed a signifiart association with cirrosis(49/86, 57%, p<0.01 by the x-test), congestive heart failure 18/35, 515, p<0.05), and diabetes mellitus(25/51, 49%, p<0.05), and otherwise not;ignificantly associated with chronic renal failure(19%), and cancer(18%). Male and female patients with TN were affected about equally. Age distribution in The patients with TN showed 35(25.8%) the age group from twenty to fortynine and 101(74.2%) in the age group from fifty and above with a mean age of 57.3+14.0, whereas the patients without TN had 178(57.8%), and 130(42.2%), with 47.4+16.9, respectively. The greater part was distributed in the older group(p<0.001 by student t-test), suggestive of an increased risk in older group. The average number of nails affected per patient was tending to be higher in frequency close to the thumb, with an equal frequency in six. Thirty-nine patients(28.7%) had all nails affected. The distal band with was 0.5 to 3.0mm averaging 1.0+0.5mm with no difference, in sex. The distal band was pink in 43(31.6%) of the 136 patients with TN, brown in 62(45.6%) and intermediate in color in 13(22,8%). The results of routine laboratory test such as hemogram, eiythrocyte sedimenation rate, liver enzyme, triglyceride, protein, albumin, blood urea nitrogen and creatinine were statistically insignificant between the patients with and without TN.
Age Distribution
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Blood Urea Nitrogen
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Chronic Disease*
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Creatinine
;
Daegu
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Female
;
Fibrosis
;
Heart Failure
;
Humans
;
Inpatients*
;
Liver
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Male
;
Nails
;
Thumb
;
Triglycerides
10.Four Cases of Perianal Streptococcal Dermatitis.
Soo Min KIM ; Young Ah KIM ; Nam Joon CHO
Korean Journal of Dermatology 2018;56(9):569-571
No abstract available.
Dermatitis*
;
Streptococcus pyogenes