1.No title available in English.
Hyun Jung SONG ; Woong Youn CHUNG ; Cheong Soo PARK
Korean Journal of Endocrine Surgery 2002;2(1):53-54
No abstract available.
2.A case of prenatal ultrasonographic diagnosis of Roberts syndrome.
Yong Hoon CHO ; Young Don YOON ; Tae Bok SONG ; Ji Soo BYUN ; Young Youn CHOI
Korean Journal of Perinatology 1992;3(1):88-94
No abstract available.
Diagnosis*
3.Epitope Mapping of HIV1 gp41 Protein for Korean Anti - HIV1 Antisera using Synthetic Peptides.
Kyung Soo HAHM ; Myung Kyu LEE ; Song Yub SHIN ; Sun Young KIM ; So Youn JANG
Korean Journal of Immunology 1997;19(1):107-112
The N-terminal sequence of HIV1 gp41 (amino acid residues 584-623) was known to be the immundominant region of HIV1 gp41 protein. In order to determine epitope for gp41 protein of Korean anti-HIV1 positive sera, multiple antigenic peptides (MAPs) for the sequences corresponding to 584-604, 590-612, 604-623 and 584-618 of HIV1 gp41 were synthesized by solid phase method using Fmoc-Lys (Fmoc)-OH and used as coating antigens for ELISA. The reactivities of the synthetic peptides with Korean HIV1 positive (21 samples) and anti-HIV1 negative sera (22 samples) obtained from healthy blood doner were estimated by an indirect ELISA. MAPs for 584-604, 590-612 and 604-623 of gp41 reacted with 62 %, 100 % and 81 % of Korean anti-HIV1 positive sera tested, respectively. The results suggest that the epitope for HIV1 gp 41 for Korean anti-HIV1 positive sera is located in the region of amino acid 590-612 of gp41. MAP for gp41 (584-618) reacted with all (100 %) of anti-HIV1 positive sera tested, but did not react with anti-HlV1 negative sera. In addition, this MAP reacted stronger with seven samples of anti-HIV1 positive sera of anti-HIV1/2 combo performance panel than the mixture of 584-604, 590-612 and 604-623 of gp41, but did not react with anti-HIV negative serum. The high sensitivity and selectivity of MAP of gp41 (584-618) suggest that this peptide as a coating antigen in an ELISA system will be useful for antibody detection of HIV1.
Enzyme-Linked Immunosorbent Assay
;
Epitope Mapping*
;
Immune Sera*
;
Peptides*
4.Perinatal Prognosis of Single Umbilical Artery.
Yoon Ha KIM ; Tae Bok SONG ; Ji Soo BYUN ; Young Youn CHOI ; Ji Young LEE
Korean Journal of Perinatology 1999;10(2):155-160
OBJECTIVE: To evaluate the perinatal prognosis of fetuses with a single umbilical artery. METHODS: From 1992 to 1998, nineteen cases with single umbilical artery(SUA) was observed in 8,704 deliveries at Chonnam University Hospital. RESULTS: Out of nineteen fetuses, thirteen fetuses with single umbilical artery were detected by antenatal ultrasonographic examination and six fetuses were detected after birth. The male to female ratio was 0.9: 1. Congenital malformations were observed in 8 babies(42.1%) and included leg deformity, esophageal atresia, imperforated anus, ventriculomegaly, meningocele, hydronephrosis, ventricular septal defect, joint contracture, cleft lip and palate, toe anomaly, imperforated anus, kyphosis, no urethra and testis, clubfoot, patent ductus arteriosus and rnild mitral regurgitation. Among 10 cases of karyotyping analysis three cases were diagnosed as trisomy 18. Fourteen fetuses(77.8%) showed growth restriction at delivery. Antenatal obstetric complications were hydramnios(n = 3), oligohydramnios(n =2), and severe preeclampsia(n = 3). CONCLUSION: Careful ultrasonographic evaluation for the identification of a SUA is necessary because of its frequent association with congenital anomaly, growth restriction and cytogenetic abnormality.
Anal Canal
;
Chromosome Aberrations
;
Cleft Lip
;
Clubfoot
;
Congenital Abnormalities
;
Contracture
;
Ductus Arteriosus, Patent
;
Esophageal Atresia
;
Female
;
Fetus
;
Heart Septal Defects, Ventricular
;
Humans
;
Hydronephrosis
;
Jeollanam-do
;
Joints
;
Karyotyping
;
Kyphosis
;
Leg
;
Male
;
Meningocele
;
Mitral Valve Insufficiency
;
Palate
;
Parturition
;
Prognosis*
;
Single Umbilical Artery*
;
Testis
;
Toes
;
Trisomy
;
Urethra
5.A Qualitative Study on Reducing Dental Anxiety through Cognitive Behavioral Therapy.
Boo Il KOH ; Youn Mi SONG ; Soo Myoung BAE
Journal of Dental Hygiene Science 2017;17(1):46-55
Many people in Korea suffer from a fear of dental treatments; however, only a few studies have focused on this population. This study assessed the effectiveness of cognitive behavioral therapy (CBT) and its interventions in reducing dental anxiety, especially when administered by trained dental staff. Using case studies, the authors analyzed the content of each session and examined the process of reducing dental anxiety. First, the authors observed that the results of both dental fear scale and subjective unit of disturbance decreased significantly with changes in cognitive distortions related to dental anxiety and that rapid improvements were noted after two therapy sessions. Second, the study reported that practicing relaxation (deep-breathing) and muscle relaxation techniques; using hand signals to indicate anxiety or discomfort; establishing an empathic relationship with the therapist; making an anxiety list; and graded insensitive and exposure along with rehearsal, were effective in coping with dental anxiety and in changing negative thoughts towards the dentist. Third, a simple cognitive behavioral intervention can be effective in reducing dental anxiety. In summary, a short-term, five-session psychological intervention with CBT produced a sustained decrease in the symptoms of dental anxiety, allowing the patients to receive the required procedures. The authors discussed the study limitations and the implication of their results on future research.
Anxiety
;
Cognitive Therapy*
;
Dental Anxiety*
;
Dental Staff
;
Dentists
;
Hand
;
Humans
;
Korea
;
Muscle Relaxation
;
Qualitative Research
;
Relaxation
6.MR Findings of Metaplastic Carcinoma of the Breast: Case Report.
Soo Ah IM ; Hak Hee KIM ; Song Yee HAN ; Youn Soo LEE
Journal of the Korean Radiological Society 2004;50(4):277-280
We report the dynamic magnetic resonance imaging findings (MRI) of a metaplastic carcinoma of the breast. A 44-year-old woman presented with a 2-month history of a mass in the right breast. The tumor showed a central irregular necrosis that was depicted upon low signal intensity on a T1-weighted image and high signal intensity on a T2-weighted image. The periphery of the tumor showed strong enhancement on a contrast enhanced T1-weighted image. The time-signal intensity curve revealed an early strong contrast enhancement and a delayed washout pattern.
Adult
;
Breast*
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Necrosis
7.Perinatal outcome of preterm infants born to severe pregnancy induced hypertension mothers with or without HELLP syndrome.
Mi Jeong KIM ; Soo Yeong KIM ; Eun Song SONG ; Young Youn CHOI ; Yoon Ha KIM ; Tae Bok SONG
Korean Journal of Perinatology 2009;20(1):44-51
PURPOSE:The aim of this study was to compare the perinatal outcome of preterm infants born to severe pregnancy induced hypertension (PIH) mothers according to the presence or absence of HELLP syndrome. METHODS:A retrospective analysis was done in 314 premature live infants born to 302 severe PIH mothers who admitted at Chonnam National University Hospital from January 2002 to May 2008. Maternal and neonatal characteristics and their outcome were compared between the groups. Statistical analysis was performed by SPSS program using Student's t test, Chi-square analysis, Fisher's exact test, and logistic regression test. RESULTS:Among 302 severe PIH mothers (single pregnancy 270, twin pregnancy 32), 84 (27.8%) were associated with HELLP syndrome. Among their 334 fetuses (singleton 270, twins 64), total 20 (6.0%) resulted in fetal death and the rate of fetal death was higher in HELLP syndrome group compared to the control group (12.2% vs. 3.4%, P=0.006). Among the 314 live premature infants, 86 (27.4%) were born to severe PIH with HELLP syndrome (study group) and 228 (72.6%) were born to the control group. There were no differences in maternal and neonatal characteristics, maternal death, neonatal morbidity and neonatal death between the groups. However, the duration of mechanical ventilation (12.2+/-14.5 vs. 7.6+/-9.9 days, P=0.019) and hospitalization (25.6+/-12.3 vs. 13.0+/-10.5 days, P=0.013) were longer in the study group. CONCLUSION:Most of severe PIH mothers complicated by preterm birth, and especially combined with HELLP syndrome showed higher fetal and perinatal death than without HELLP syndrome. Moreover, their live-born premature infants needed longer duration of mechanical ventilation and hospitalization. These results indicate that careful fetal monitoring and delivery with the co-operations of obstetricians and neonatologists is essential to improve the perinatal outcome.
Female
;
Fetal Death
;
Fetal Monitoring
;
Fetus
;
HELLP Syndrome
;
Hospitalization
;
Humans
;
Hypertension, Pregnancy-Induced
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Logistic Models
;
Maternal Death
;
Mothers
;
Pregnancy
;
Pregnancy, Twin
;
Premature Birth
;
Respiration, Artificial
;
Retrospective Studies
;
Twins
8.The Clinical Characteristics and Outcome of Neonates born to Systemic Lupus Erythematosus Mothers.
Hyun Soo KANG ; Song Eun SONG ; Jae Sook MA ; Young Youn CHOI ; Tae Bok SONG
Journal of the Korean Society of Neonatology 2006;13(1):139-148
PURPOSE: Neonatal lupus erythematosus (NLE) is a rare disorder caused by the transplacentally transmitted maternal autoantibodies. It is characterized by congenital complete atrioventricular block (CCAVB), skin lesion and less commonly hepatic and hematologic abnormalities. This study was designed to investigate the clinical characteristics and outcome of systemic lupus erythematosus (SLE) mothers and their neonates. METHODS: 29 neonates born to 25 SLE mothers were admitted to the Neonatal Intensive Care Unit of Chonnam University Hospital between January 1994 and June 2005. We investigate the medical records retrospectively. RESULTS: Among 25 SLE mothers, 32.4% had history of spontaneous abortion or stillbirth in previous pregnancy, and 7 (28.0%) of preeclampsia and 3 (12.0%) of premature rupture of membranes in present pregnancy. Among 29 newborns, 14 (48.2%) were premature, 4 (13.7%) were intrauterine growth retardation, and 11 (37.9%) were confirmed as NLE. Anti-SSA/Ro was positive in 13 (52.0%) of 25 examined neonates including 6 (85.7%) of 7 neonates with electrocardiographic abnormalities. Two cases of CCAVB were diagnosed during the pregnancy. One patient didn't show heart failure, he is on the followed up without medical treatment until 4 years of age. The other one showed heart failure, cardiac pacemaker was inserted at 7 days of age, dilated cardiomyopathy developed at 4 years of age. Five neonates with sinus bradycardia resolved spontaneously. One (3.4%) had typical lupus skin lesion with thrombocytopenia and elevated liver enzyme, one (3.4%) had leukopenia, and two (6.9%) had elevated liver enzymes only. CONCLUSIONS: With careful antenatal monitoring of SLE mothers and their fetuses, neonates should be monitored by autoantibody, EKG, and laboratory test.
Abortion, Spontaneous
;
Atrioventricular Block
;
Autoantibodies
;
Bradycardia
;
Cardiomyopathy, Dilated
;
Electrocardiography
;
Female
;
Fetal Growth Retardation
;
Fetus
;
Heart Failure
;
Humans
;
Infant, Newborn*
;
Intensive Care, Neonatal
;
Jeollanam-do
;
Leukopenia
;
Liver
;
Lupus Erythematosus, Systemic*
;
Medical Records
;
Membranes
;
Mothers*
;
Pre-Eclampsia
;
Pregnancy
;
Retrospective Studies
;
Rupture
;
Skin
;
Stillbirth
;
Thrombocytopenia
9.Fetal Head Injury due to Penetrating Abdominal Stab Wound in a 31 Weeks Pregnant Woman.
Eun Song SONG ; Soo Young KIM ; Young Youn CHOI ; Yoon Ha KIM ; Tae Bok SONG
Korean Journal of Perinatology 2009;20(3):249-253
Penetrating trauma in a fetus is uncommon but may cause potentially life-threatening injuries. We experienced a case of preterm infant who delivered by C-section and showed two deep laceration wounds on face, facial nerve palsy, skull fracture and intracranial hemorrhage due to penetrating injury of an abdominal stab wound in a 31 weeks pregnant woman.
Craniocerebral Trauma
;
Facial Nerve
;
Female
;
Fetus
;
Head
;
Humans
;
Infant, Newborn
;
Infant, Premature
;
Intracranial Hemorrhages
;
Lacerations
;
Paralysis
;
Pregnant Women
;
Skull Fractures
;
Wounds, Stab
10.Two Cases of Oculocardisc Reflex - A Case Report .
Youn Jae SONG ; Chan Jin PARK ; Sang Soo KIM
Korean Journal of Anesthesiology 1982;15(4):569-572
Ocular muscle manipulation used to elicit varying cardiac arrythmias, even cardiac arrest, due to oculocardiac reflex. The authors experienced two cases of typical arrythmias during general anesthesia(halothane-N20), in spite of medication of belladonna alkalold preoperatively. According to other reports, was observed bradycardia in case of ocular muscle manipulation during general anesthesis, but we observed ventricular extrasystole and nodal rhythm. The use of belladonna alkaloid for the prevention of cardiac arrythmias during ocular muscle manipulation might be questioned.