No abstract available.
Risk Factors*

No abstract available.
Antibodies, Monoclonal* ; Mycobacterium bovis*

Clinical and bacteriological studies, including seasitivity tests, of 85 patients in pyodermas such as impetigo contagiosa, pustular acne vulgaris, hair follicle and sweat gland infections, and secondary pyogenic infections superimposed on primary dermatoses were carried out during 4 months period, from June 1970 to Sept.1970, at department of dermatology, schooI of medicine, Seoul national university. The results were as follows; 1) Predominant age group of impetigo was the preschool. ages (87%). 2) Causative agents of impetigo in our 30 cases were coagulase positive staphylococcus aureus only in 27, streptococcus only in 0 and both organisms in 3 (one case wasmixed infection with s. aureus and b-hemolytic streptococcus, and two were mixed infections with s. aureus and a-hemolytic streptococcus). 3) Culturing from l2 cases of pustular acne vulgaris, we found coagulase negative staphylococcus albus in 9, coagulase positive stsphylococcus aureus in 1 and no growth in 2. 4) In 35 cases of hair follicle and sweat gland infections, we isolated coagulase positivestaphylococcus aureus only in 32, coagulase negative staphylococcus albus only in 2, and mixed infection with staphylococcus aureus and b-hemolytic streptococcus in l. 5) Isolated organisms in 8 cases of secondary pyogenic infections superimposed on primary dermatoses were coagulase positive staphylococcus aureus only in 2, coagulase negative staphylococcus albus only in 1, b-hemolytic streptococcus only in 1, a- hemolytic streptococcus only in 1, and mixed infections with various combination in 3. 6) Results of sensitivity tests with isolated organisms in the above diseases groups were as follows; (a) Total 66 strains of coagulase positive staphylococcus aureus showed resistance to ampicillin in 97.0%, penicillin in 78.8%, terramycin in 72.7%, rizynomycin in 71.2%, streptomycin in 24.1%, chloramphenicol in 16.7%, neomycin in 12.1%, kanamycin in 4.5% and leukomycin in 1.5%, (b) Total 8 strains of hemolytic streptococci were sensitive to chloramphenicol, leukomycin and penicillin.
Acne Vulgaris ; Ampicillin ; Chloramphenicol ; Coagulase ; Coinfection ; Dermatology ; Hair Follicle ; Humans ; Impetigo ; Kanamycin ; Neomycin ; Oxytetracycline ; Penicillins ; Pyoderma* ; Seoul ; Skin Diseases ; Staphylococcus ; Staphylococcus aureus ; Streptococcus ; Streptomycin ; Sweat Glands

Various concentrations, including 100%, 75%, 50%, and 25% of dimethyl sulfoxide (DMSO) were applied on the back of albino rats, followed by ultraviolet irradiation after 30 minutes. Biopsy specimens were taken 6, 12, 24, 36, and 48 hours afters ultraviolet irradiation without local anesthesia. The macroscopic and histologic findings were as follows. 1. Mild degree of erytheme appeared only on the site of the highest concentration (100%) of DMSO. 2. Vacuolization of the prickle cells appeared slightly later on the sites of higher concentrations (75% and 100%) than those of lower concentrations and control. 3. After 48 hours post-irradiation, there was no detectable vacuolization on the sites of higher concentrations, whereas marked vacuolization still remained on the other sites. 4. More pronounced epidermal thickening could be observed on the sites of higher concentrations than the sites of lower concentrations and control. 5. The dermal edema was more completely disappeared on the sites of higher concentrations than the sites of lower concentrations and control, 48 hours after ultraviolet irradiation.
Anesthesia, Local ; Animals ; Biopsy ; Dimethyl Sulfoxide* ; Edema ; Rats

No abstract available.
Arm* ; Free Tissue Flaps*

OBJECTIVE: This study was aimed to obtain information on normal MIS serum levels according to menstrual cycles of adult normal cycling women . It was also designed to obtain information on the ontogeny of the production profile of MIS and the pattern of its localization in ovary from adult normal cycling women. METHODS: Between January 1998 and January 1999, normal MIS serum levels were measured according to menstrual cycles using 160 serum samples from adult normal cycling women by ELISA. The ontogeny of the production profile of MIS and the pattern of its localization were also studied by immunohistochemical staining using the rabbit polyclonal antibody against human recombinant MIS in 35 ovarian specimens from adult normal cycling women. RESULT: The MIS levels were gradually increased through the follicular phase, reaching at its maximum at the ovulatory phase(4.2+/-2.6 ng/ml), and sharply decreased at the beginning of the luteal phase being minimized at the premenstrual phase(0.5+/-0.2 ng/ml). In average, the MIS levels of the follicular phase(3.7+/-1.9 ng/ml) were significantly higher than those of the luteal phase(1.8+/-2.4 ng/ml)(P<0.05). The MIS levels of the preovulatory and ovulatory phase were significantly higher than those of the other cycle days(P<0.05). Even the early follicular phase(2.9+/-1.6 ng/ml) showed higher MIS levels than the advanced luteal phase(0.9+/-0.7 ng/ml) and the premenstrual phase(0.5+/-0.2 ng/ml)(P<0.05 and P<0.05, respectively). The first staining for MIS was detected in the cytoplasm of granulosa cells when the flattened granulosa cells changed to the cuboidal cells in primordial follicles. The granulosa cells of both single and multiple layered growing follicles showed strong specific staining for MIS. but the MIS staining was not found not in the mature follicle just before ovulation, atretic follicles, corpus luteum, and corpus albicans. MIS staining waned in the mature follicles just before ovulation. CONCLUSION: These experiments demonstrate that the MIS is produced by ovarian granulosa cells in normal reproductive females. The MIS may play an important role as a hormone of follicular development and oocyte maturation through interactions with female steroid hormones, gonadotropins, and growth factors during the adult reproductive cycle.
Adult ; Anti-Mullerian Hormone* ; Corpus Luteum ; Cytoplasm ; Enzyme-Linked Immunosorbent Assay ; Female ; Follicular Phase ; Gonadotropins ; Granulosa Cells ; Humans* ; Intercellular Signaling Peptides and Proteins ; Luteal Phase ; Menstrual Cycle* ; Oocytes ; Ovarian Follicle ; Ovary* ; Ovulation

No abstract available.
Animals ; Macrophages, Peritoneal* ; Mice* ; Mycobacterium bovis*

Infantile hypertrophic pyloric stenosis(IHPS), which occurs three of 1,000 live births, is a major cause of 1 nonbilious vomiting of early infancy but its etiology and pathogenesis are still obscure. The operation of pyloromyotomy as described by Ramstedt in 1912 remains the standard of care for the treatment of IHPS. From January 1993 to October 1996, 35 infants with IHPS were surgically treated and the following results were obtained. 1. Thirty-five patients comprised 32 males and 3 females, and the ratio of male to female was 10.7:1. 2. The most prevalent age group was between 2 weeks and 8 weeks. 3. Of 35 infants, first born babies were 23 cases(65.7%). 4. Breast feeding was in 23 cases(65.7%). 5. The body weight percentile at admission was lower than 50 percentile in all 35 cases. 11. A total of seven associated anomalies were noted in six patients. 12. All 35 cases were treated with Fredet-Ramstedt pyloromyotomy. 13. There were postoperative complications of wound infection in 2 cases. Intermittent nonprojectile vomiting was presented in 8 cases(22.9%) after operation, but one of them was relieved in 13 days and the rest were relieved within one week by adjustment of oral intake.
Body Weight ; Breast Feeding ; Female ; Humans ; Infant ; Live Birth ; Male ; Postoperative Complications ; Pyloric Stenosis, Hypertrophic* ; Standard of Care ; Vomiting ; Wound Infection

No abstract available.
Hemoptysis*

Male urethral diverticulum is uncommon lesion, furthermore calculus formation within the male urethral diverticulum is very rare. Generally, urethral diverticula are classified as congenital and acquired. The majority of male urethral diverticula are acquired and approximately 10 to 20 per cent are congenital. Acquired urethral diverticula in the male may arise from many sources, including infection (prostatic abscess, infection of periurethral glands, hematoma or schistosomiasis), obstruction (stricture, impacted stone, Cunningham clamp or condom catheter) and trauma (instrumentation, external injury and pelvic fracture). Calculi formation is more common in the acquired diverticulum owing to stagnation of urine and infection. These calculi in the diverticulum usually are solitary and may attain considerable size with predisposing factors, 1) a ureteral or bladder calculus that is lodged in the urethra 2) urethral trauma or stricture, 3) calcification around a foreign body or hair. The treatment of urethral diverticulum combined with stone is excision of the diverticula with removal of stone. We treated two cases of urethral diverticulum combined with stone in the male, and report with review of literature.
Abscess ; Calculi ; Causality ; Condoms ; Constriction, Pathologic ; Diverticulum* ; Foreign Bodies ; Hair ; Hematoma ; Humans ; Male* ; Ureter ; Urethra ; Urinary Bladder Calculi