1.Food ( wheat flour ) dependent exerclse - induced anaphylaxis in asthmatics : related with the amont of wheat flour and exercise.
Mi Kyung KIM ; Kyung Soo LEE ; Mi Sung KIM
Journal of Asthma, Allergy and Clinical Immunology 1999;19(5):724-729
A 25-year-old male with asthma suffered from generalized urticaria, angioedema and syncope associated with exercise after ingestion of food made with wheat flour. Skin prick test with bread showed strong positive reaction(++++), but with wheat flour, a weak positive(+). Challenge test with wheat flour, and food made with wheat flour, without or with exercise, were done several times. Exercise such as 25 min of running on treadmill following 30 min after 50 grams of bread or 50 grams of hot pepper-stuffed rice cake only showed positive reaction such as generalized urticaria, angioedema and hypotension, but not with 15 grams of bread or 15 grams of hot pepper-stuffed rice cake. Ingestion of bread in such high amounts as 15 grams alone did not trigger reaction, not even with is min of exercise. This is the first clear case of food dependent exercise induced anaphylaxis (FDEIA) in which the allergic reaction depended on both the amount of food ingested and the amount of exercise was clarified.
Adult
;
Anaphylaxis*
;
Angioedema
;
Asthma
;
Bread
;
Eating
;
Flour*
;
Humans
;
Hypersensitivity
;
Hypotension
;
Male
;
Running
;
Skin
;
Syncope
;
Triticum*
;
Urticaria
2.Differences in allergen - specific Th and Tc cel responses between pre - and post - immunotherapy asthmatics.
Mi Ran KANG ; Mi Kyung KIM ; Youn Soo HAHN
Journal of Asthma, Allergy and Clinical Immunology 1999;19(5):656-665
BACKGROUND: Allergen-specific immunotherapy ( IT ) can be an important adjunctive therapy in the treatment of allergic disorders. Although a number of studies have shown that cytokine production by T cells may be modified by IT, IT-induced chsnges at the single cell level in allergen -specific Th ( T helper ) and Tc ( cytotoxic T ) responses have not been reported. Objective : The objectives of the present study were ( 1 ) to demonstrate differences in the house dust mite(HDM)-induced cytokine production patterns of Th and Tc cells between untreated and treated HDM allergic patients and ( 2 ) to determine whether there are differences between child and adult patients in Th and Tc cell responses to HDM. METHOD: This study included twenty Dermatophagoides farinae (Df)-sensitive asthmatics ( ten children and ten adults ), of which five children and five adults received immunotherapy to Df over a 1.5- to 3-year period. Peripheral blood mononuclear cells ( PBMC ) were isolated from peripheral blood of each patient and cultured in the presence of IL-2 ( 10ng/ml ) and Df extract (100ug/ml) for 6 days. After harvesting cultured cells, Th and Tc cell frequencies were determined by a multiparameter cytokine flow cytometric assay that allows simultaneous determination of intracellular IFN-r and IL-4 in CD4+ or CD8+ cells. RESULTS: Predominant Th2 responses to Df were observed in all untreated child patients, three untreated adult patients, and two treated adult patients. On the other hand, predominant Thl responses to Df were observed in all treated child patients, two of untreated adult patients, and three of treated adult patients. Predominant Tcl responses to Df were observed in all groups of patients. However, Tcl responses were more prominent in adults than in children and in treated adult patients than in untreated adult patients. In children, there were no differences in predominant Tcl responses except in one treated child, in whom more prominent Tcl response was observed.
Adult
;
Cells, Cultured
;
Child
;
Dermatophagoides farinae
;
Dust
;
Hand
;
Humans
;
Immunotherapy*
;
Interleukin-2
;
Interleukin-4
;
T-Lymphocytes
3.Acute Pulmonary Mycetoma Due to Candida albicans in AML patient.
Jae Kyo LEE ; Mi Soo HWANG ; Mi Jin KIM
Yeungnam University Journal of Medicine 1995;12(1):135-140
Acute cavitating pulmonary infection with a mycetoma is sometimes occur in immunocompromised patient. Most mycetoma lesions are due to Aspergillus species, and lesion caused by Candida species is rare. So we report an experienced case that pulmonary and rib infection caused by Candida species-'in -AML patient and complete remission with previous reports.
Aspergillus
;
Candida albicans*
;
Candida*
;
Candidiasis
;
Humans
;
Immunocompromised Host
;
Lung Diseases, Fungal
;
Mycetoma*
;
Ribs
4.A Study on the Thyroin Function Test in Patients with Nonthyroidal Illness.
Journal of the Korean Pediatric Society 1989;32(3):381-389
No abstract available.
Humans
5.Radiologic Analysis of Tuberculous Spondylitis.
Yeungnam University Journal of Medicine 1986;3(1):95-102
Among the skeletal tuberculous spondylitis is high incidence and curable disease, if early diagnosis and treatment are possible. We reviewed clinical manifestations and radiologic analysis of 30 cases tuberculous spondylitis from May 1983 to Sept. 1986, at Yeungnam medical center, Yeungnam University. The results were follows: 1. The frequent involve sites were thoracolumbar vertebra. 2. The continuous lesion is 86.7% of the all cases. 3. The most common type was intervertebral type, and lytic and sclerotic lesion were same incidence. 4. Paravertebral abscess, kyphosis and disc space narrowing were demonstrated more than 80.0% of the cases. 5. Computed tomography was more accurate diagnostic method rather than conventional plain study to evaluation of extent of lesion, involvement of spinal canal and cord, and size and location of paravertebral abscess. And CT guided abscess drainage procedure was helpful to diagnosis and treatment. 6. Ultrasonography was helpful to differential diagnosis between paravertebral abscess and other solid mass, and useful to follow up study of paravertebral abscess after treatment.
Abscess
;
Diagnosis
;
Diagnosis, Differential
;
Drainage
;
Early Diagnosis
;
Follow-Up Studies
;
Incidence
;
Kyphosis
;
Methods
;
Spinal Canal
;
Spine
;
Spondylitis*
;
Ultrasonography
6.Occupational asthma induced by ganoderma spores.
Journal of Asthma, Allergy and Clinical Immunology 1999;19(5):720-723
Occupational asthma induced by the inhalation of the spore of Ganoderma lucidum was demonstrated in a 43-year-old woman who had cultivated it indoors for 6 years. She had suffered from paroxysmal cough and rarely wheezing dyspnea for two years. Recently she also had chest tightness and paroxysmal and repeated cough immediately after the exposure to Ganoderma lucidum spores. Her pulmonary function was normal. But, her PC20 was 6.4mg/ml in MBPT (methacholine bronchial provocation test). She showed not only positive reaction to skin prick test but also dual asthmatic reaction to the bronchial challenge test with antigenic extract of Ganoderma lucidum spores.
Adult
;
Asthma, Occupational*
;
Bronchial Provocation Tests
;
Cough
;
Dyspnea
;
Female
;
Ganoderma*
;
Humans
;
Inhalation
;
Reishi
;
Respiratory Sounds
;
Skin
;
Spores*
;
Thorax
7.A case of ruptured interstitial pregnancy with 19 weeks gestation.
Do Yung CHOI ; Mi Kyung KIM ; Hyang Mi LEE ; Hye Mi LEE ; Sam Soo HO
Korean Journal of Obstetrics and Gynecology 1993;36(1):106-115
No abstract available.
Pregnancy*
8.Induction of ovulation with follicle-stimulation hormone human menopausal gonadotropin and human chorionic gonadotropin: Correlation of multiple follicular-oocytes development and serum E2 levels as well as fertilizability in ovulatory patients for in vit.
Young Soo KANG ; Mi Young JANG ; Hyang Mi KIM ; Young Soo SON ; Bock Hee WOO
Korean Journal of Obstetrics and Gynecology 1993;36(3):339-352
No abstract available.
Chorionic Gonadotropin*
;
Female
;
Gonadotropins*
;
Humans*
;
Ovulation*
9.CLINICOPATHOLOGIC ANALYSIS OF THE PLEOMORPHIC ADENOMA.
Yeong Mi KIM ; Yong Gyoo LEE ; Chin Soo KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(4):716-727
The author studied on the 197 cases of the pleomorphic adenoma which had been diagnosed with biopsy during the period of 1985 to 1996 at the Kyungpook National University Hospital. This study contains the statistical analysis of the clinico-pathological findings such as sex, age, location, chief complaint, duration, treatment method, size, recurrence, and treatment department in relation to anatomical location. The result were as follows : 1. The treatment department in oxter were ENT(16.2%), GS(22.8%), OMFS(18.8%), PS(12.2%). 2. The incidence of pleomorphic adenoma were parotid gland(57.8%), palatal salivary gland(20.3%), submandibular gland(17.2%), other minor salivary glands(4.5%). 3. The tumors were more common in females than males, with a male to female ratio of 1 : 1.85. 4. The peak age of ocurrence was in the forth decade. 5. The duration of the most cases were less than 5 years. 6. Although the size of the tumors was variable, the incidence was highest between 3cm and 4cm(25.4%). 7. The most prevalent chief complaint was swelling(94.9%). 8. Conservative treatment was performed 30.0%, and radical treatment was employed 70.0%. 9. The recurrence rate is 8.1%, and recurrence used to be relatively common with conservative treatment. 10. The rate of malignant transformation is 1%. 11. The anatomical location has no relationship with the factors of sex, duration, and malignant transformation. 12. There was statistical significance on the anatomical location to the treatment department, age, chief complaint, size, treatment method, recurrence (P<0.05).
Adenoma, Pleomorphic*
;
Biopsy
;
Female
;
Gyeongsangbuk-do
;
Humans
;
Incidence
;
Male
;
Recurrence
10.Pulmonary Arteriovenous Fistula in Childbood: Report of a case.
Soo Min KANG ; Mi Kyung KIM ; Je G CHI
Korean Journal of Pathology 1992;26(2):201-203
A case of pulmonary arteriovenous fistula in a 8-year-old boy who presented with easy fatigability and cyanosis for 4 months, is described. Grossly, there was a large vascular anomaly measuring 2x2 cm in the center of the removed right lower lobe. Microscopically, the lesion consisted of dilated arterial and venous structures resembling a cavernous hemangioma. Subintimal fibrosis and attenuated vascular structure lacking elastic fiber and representing A-V shunt were also noted in the lesion.
Child
;
Male
;
Female
;
Humans