1.Cord Blood Insulin Concentration in Premature Neonates with Respiratory Distress Syndrome.
Soo Jung KEUM ; Rak Won CHOI ; Mi Youn CHUNG ; Dong Hyuck KUM
Journal of the Korean Pediatric Society 1989;32(10):1402-1407
No abstract available.
Fetal Blood*
;
Humans
;
Infant, Newborn*
;
Insulin*
2.A Case of Stent Migration into Right Ventricle after Percutaneous Transluminal Angioplasty for Budd-Chiari Syndrome.
Mi Ran SIM ; Wha Sook KIM ; Won Kyung PARK ; Gae Hyuk MOON ; Eui Soo HONG ; Jeong Kee SEO ; Seong CHO ; June KWAN ; Keum Soo PARK ; Woo Hyung LEE
Korean Circulation Journal 2000;30(7):885-889
No abstract available.
Angioplasty*
;
Budd-Chiari Syndrome*
;
Heart Ventricles*
;
Stents*
3.Changes of Interleukin-10 and Granulocyte Colony-Stimulating Factor in Cerebrospinal Fluid of Children with Aseptic Meningitis.
Byeong Chan PARK ; Jung Yeon SHIM ; Jeong Mi LEE ; Jin Young PARK ; Myung Ja YOON ; Hye Rim JUNG ; Moon Soo PARK ; Dong Hyeuk KEUM ; Dong Keug KEUM
Journal of the Korean Pediatric Society 1999;42(12):1676-1682
PURPOSE: Interleukin(IL)-10 is an antiinflammatory cytokine produced by monocytes/macrophages. Granulocyte colony-stimulating factor(G-CSF) plays an important role, not only as a hemopoietic factor but also as a regulating factor for a biologic defense system by neutrophils, in the foci of infection. We studied G-CSF and IL-10 levels in the serum and cerebrospinal fluid(CSF) of patients with aseptic meningitis and investigated the relationship of G-CSF and IL-10 with other inflammatory cells. METHODS: We measured IL-10 and G-CSF levels in the serum and CSF of children with or without aseptic meningitis using ELISA and compared them with other inflammatory cells in the CSF. RESULTS: CSF levels of IL-10 & G-CSF on admission were significantly higher in the aseptic meningitis group than in the control group. IL-10 and G-CSF levels in the CSF were higher than those in the serum(P<0.001). Mean CSF IL-10 & G-CSF levels during the recovery stage decreased significantly compared to those of the symptomatic stage(P<0.001). Significant correlations were found between CSF IL-10 levels and mononuclear cell counts(r=0.26, P<0.05), and between G-CSF levels and neutrophil counts in the CSF(r=0.44, P<0.005). CSF levels of G-CSF were highest on the 1st day of the illness, although CSF IL-10 levels reached its peak on the 3rd day of the illness. CONCLUSION: IL-10 and G-CSF are produced in the CSF of patients with aseptic meningitis and may play an immunoregulatory role by recruiting inflammatory cells from the peripheral blood at the initial stage of aseptic meningitis.
Cerebrospinal Fluid*
;
Child*
;
Enzyme-Linked Immunosorbent Assay
;
Granulocyte Colony-Stimulating Factor*
;
Granulocytes*
;
Humans
;
Interleukin-10*
;
Meningitis, Aseptic*
;
Neutrophils
4.Changes of Interleukin-10 and Granulocyte Colony-Stimulating Factor in Cerebrospinal Fluid of Children with Aseptic Meningitis.
Byeong Chan PARK ; Jung Yeon SHIM ; Jeong Mi LEE ; Jin Young PARK ; Myung Ja YOON ; Hye Rim JUNG ; Moon Soo PARK ; Dong Hyeuk KEUM ; Dong Keug KEUM
Journal of the Korean Pediatric Society 1999;42(12):1676-1682
PURPOSE: Interleukin(IL)-10 is an antiinflammatory cytokine produced by monocytes/macrophages. Granulocyte colony-stimulating factor(G-CSF) plays an important role, not only as a hemopoietic factor but also as a regulating factor for a biologic defense system by neutrophils, in the foci of infection. We studied G-CSF and IL-10 levels in the serum and cerebrospinal fluid(CSF) of patients with aseptic meningitis and investigated the relationship of G-CSF and IL-10 with other inflammatory cells. METHODS: We measured IL-10 and G-CSF levels in the serum and CSF of children with or without aseptic meningitis using ELISA and compared them with other inflammatory cells in the CSF. RESULTS: CSF levels of IL-10 & G-CSF on admission were significantly higher in the aseptic meningitis group than in the control group. IL-10 and G-CSF levels in the CSF were higher than those in the serum(P<0.001). Mean CSF IL-10 & G-CSF levels during the recovery stage decreased significantly compared to those of the symptomatic stage(P<0.001). Significant correlations were found between CSF IL-10 levels and mononuclear cell counts(r=0.26, P<0.05), and between G-CSF levels and neutrophil counts in the CSF(r=0.44, P<0.005). CSF levels of G-CSF were highest on the 1st day of the illness, although CSF IL-10 levels reached its peak on the 3rd day of the illness. CONCLUSION: IL-10 and G-CSF are produced in the CSF of patients with aseptic meningitis and may play an immunoregulatory role by recruiting inflammatory cells from the peripheral blood at the initial stage of aseptic meningitis.
Cerebrospinal Fluid*
;
Child*
;
Enzyme-Linked Immunosorbent Assay
;
Granulocyte Colony-Stimulating Factor*
;
Granulocytes*
;
Humans
;
Interleukin-10*
;
Meningitis, Aseptic*
;
Neutrophils
5.Efficacy of ondansetron is cisplatin-induced nausea and vomiting.
Keum Jung KIM ; Jung Baik KIM ; Kwang Mi KIM ; Jung Sook PARK ; Soo Hee PARK ; Si Young KIM ; Hwi Joong YOON ; Kyung Sam CHO
Journal of the Korean Cancer Association 1993;25(6):975-981
No abstract available.
Nausea*
;
Ondansetron*
;
Vomiting*
6.Proton MR Spectroscopic Features of Liver Cirrhosis: Comparing with Normal Liver.
Soon Gu CHO ; Won CHOI ; Young Soo KIM ; Mi Young KIM ; Keum Nahn JEE ; Kyung Hee LEE ; Chang Hae SUH
Journal of the Korean Radiological Society 2000;42(4):643-648
PURPOSE: The purpose of this study was to determine the proton MR spectroscopic features of liver cirrhosis and the different proton MR spectroscopic features between liver cirrhosis and the normal human liver by comparing the two different conditions. MATERIALS AND METHODS: The investigation involved 30 cases of in-vivo proton MR spectra obtained from 15 patients with liver cirrhosis demonstrated on the basis of radiologic and clinical findings, and from 15 normal volunteers without a past or current history of liver disease. MR spectroscopy involved the use of a 1.5T GE Signa Horizon system (GE Medical Systems, Milwaukee, U.S.A.) with body coil. STEAM (STimulated Echo-Aquisition Mode) with 3000/30 msec of TR/TE was used for signal acquisition; patients were in the prone position and respiration was not interrupted. Cases were assigned to either the cirrhosis or normal group, and using the proton MR spectra of cases of in each group, peak changes occurring in lipids (at 1.3ppm), glutamate and glutamine (at 2.4 -2 .5ppm), phosphomonoesters (at 3.0 -3 .1ppm), and glycogen and glucose (at 3.4 -3 .9ppm) were evaluated. Mean and standard deviation of the ratio of glutamate + glutamine/lipids, phospho-monoesters/lipids, glycogen + glucose/lipids were calculated from the area of their peaks. The ratio of various metabolites to lipid content was compared between the normal and cirrhosis group. RESULTS: The main characteristic change in proton MR spectra in cases of liver cirrhosis compared with normal liver was decreased relative intensity of lipid peak. Mean and standard deviation of ratio of glutamate + g-lutamine/ lipids, phosphomonoesters/lipids, glycogen + glucose/lipids calculated from the area of their peaks of normal and cirrhotic liver were 0.0204 +/-0.0067 and 0.0693 +/-0.0371 (p<0.05), 0.0146 +/-0.0090 and 0.0881 +/-0.0276 (p<0.05), 0.0403 +/-0.0267 and 0.2325 +/-0.1071 (p<0.05), respectively. The other character-istic feature of proton MR spectra of liver cirrhosis was the peak detected at 3.9 - 4.1 ppm with unknown nature. Mean and standard deviation of area ratio of the unknown peak to lipid peak in proton MR spectra of liver cirrhosis was 0.1504 +/-0 . 0 3 5 5 . CONCLUSION: Proton MR spectra of liver cirrhosis revealed decreased intensity of lipid with statistical signifi-cance compared with that of normal liver, and peak at 3.9 -4.1 ppm with unknown nature. In conclusion, liver cirrhosis can be diagnosed non-invasively by the analysis of observed proton MR spectroscopic features.
Fibrosis
;
Glucose
;
Glutamic Acid
;
Glutamine
;
Glycogen
;
Healthy Volunteers
;
Humans
;
Liver Cirrhosis*
;
Liver Diseases
;
Liver*
;
Magnetic Resonance Spectroscopy
;
Prone Position
;
Protons*
;
Respiration
;
Steam
7.Effect of Thymol and Linalool Fumigation on Postharvest Diseases of Table Grapes.
Mi Ho SHIN ; Jin Hee KIM ; Hyo Won CHOI ; Yoong Soo KEUM ; Se Chul CHUN
Mycobiology 2014;42(3):262-268
Several postharvest diseases of table grapes (Vitis vinifera) occur during storage, and gray mold rot is a particularly severe disease because the causal agent, Botrytis cinerea, grows at temperatures as low as 0degrees C. Other postharvest diseases, such as those caused by Penicillium spp. and Aspergillus spp., also often lead to deterioration in the quality of table grapes after harvest. The use of plant essential oils such as thymol and linalool, to reduce postharvest diseases in several kinds of fruits, including table grapes and oranges, has received much attention in European countries. However, to the best of our knowledge there has been no report of the use of thymol fumigation to control gray mold in table grapes in Korea. Thymol (30 microg/mL) and linalool (120 microg/mL) significantly inhibited mycelial growth and conidia germination of B. cinerea. The occurrence rate of gray mold rot of B. cinerea and other unknown fungi was significantly reduced by fumigation with 30 microg/mL thymol in several table grape cultivars, such as Campbell early, Muscat Bailey A, Sheridan, and Geobong. In this study, fumigation with 30 microg/mL thymol, had no influence on the sugar content and hardness of grapes, but reduced fungal infection significantly. This suggests that 30 microg/mL thymol could be utilized to reduce deterioration of grapes due to gray mold and other fungal infections during long-term storage.
Aspergillus
;
Botrytis
;
Citrus sinensis
;
Fruit
;
Fumigation*
;
Fungi
;
Germination
;
Hardness
;
Korea
;
Oils, Volatile
;
Oman
;
Penicillium
;
Plants
;
Spores, Fungal
;
Thymol*
;
Vitis*
8.Primary intracranial hemorrhage presenting as acute myocardial ischemic syndrome.
Eun Sang KUWON ; Sim Mi LAN ; Hyun Joo SHIN ; Eyi Soo HONG ; Jeong Kee SEO ; Seong Wook JO ; June KWAN ; Keum Soo PARK ; Woo Hyung LEE
Korean Journal of Medicine 1998;55(5):951-955
A 44 years old woman was admitted to Inha University hospital in semicomatose state. An electrocardiogram (ECG), taken in the emergency room, showed ST segment elevation in the precordial leads. She underwent a urgent echocardiography. It showed that there was akinesia of anteroseptal segment from the mid left ventricle to the apex and inferior segment from the mid left ventrile to the lower mid left ventricle. With the impression of acute myocardial infarction (AMI), she underwent a urgent coronary angiography. There was no significant luminal narrowing of the right or the left coronary arteries but the left ventriculography revealed akinesia of anterolateral and diaphragmatic segments of the left ventricle. Computerized tomography (CT) of the brain, taken shortly after coronary angiography, showed subarachnoid hemorrhage. The abnormal ECG and echocardiography findings, simulating acute myocardial infarction, were assumed to be caused by coronary vasospasm derived from subarachnoid hemorrhage accompanied by massive adrenergic discharge.
Adult
;
Brain
;
Coronary Angiography
;
Coronary Vasospasm
;
Coronary Vessels
;
Echocardiography
;
Electrocardiography
;
Emergency Service, Hospital
;
Female
;
Heart Ventricles
;
Humans
;
Intracranial Hemorrhages*
;
Myocardial Infarction
;
Phenobarbital
;
Subarachnoid Hemorrhage
9.Bone mineral density and bone turnover markers in patients on long-term suppressive levothyroxine therapy for differentiated thyroid cancer.
Mi Young LEE ; Jae Hyun PARK ; Keum Seok BAE ; Yong Gwan JEE ; An Na KO ; Yong Jea HAN ; Jang Yel SHIN ; Jung Soo LIM ; Choon Hee CHUNG ; Seong Joon KANG
Annals of Surgical Treatment and Research 2014;86(2):55-60
PURPOSE: Current management for patients with differentiated thyroid cancer includes near total thyroidectomy and radioactive iodine therapy followed by administration of supraphysiological doses of levothyroxine (L-T4). Although hyperthyroidism is a well known risk factor for osteoporosis, the effects of L-T4 treatment on bone mineral density (BMD) in patients with thyroid cancer do not appear to be as significant as with endogenous hyperthyroidism. In this study, we evaluated the impact of long-term suppressive therapy with L-T4 on BMD and bone turn over markers in Korean female patients receiving L-T4 suppressive therapy. METHODS: We enrolled 94 female subjects (mean age, 50.84 +/- 11.43 years) receiving L-T4 after total or near total thyroidectomy and radioactive iodine therapy for thyroid cancer (mean follow-up period, 12.17 +/- 4.27 years). The subjects were divided into three groups by thyroid stimulating hormone (TSH) level (group 1 with TSH level < or =0.001 microIU/mL, group 2 with TSH level between 0.001 and 0.17 microIU/mL, group 3 with TSH level >0.17 microIU/mL) and four groups by quartile of free T4 level. L-T4 dosage, BMD (examined by dual-energy x-ray absorptiometry), and bone turnover markers were evaluated according to TSH and free T4 levels. RESULTS: No significant decrease was detected in BMD or bone turnover markers according to TSH level or free T4 level. Also, the prevalence of osteoporosis and osteopenia was not different among groups. CONCLUSION: Long-term L-T4 suppressive therapy after thyroid cancer management did not affect bone density or increase the prevalence of osteoporosis even though TSH levels were supraphysiologically suppressed.
Bone Density*
;
Bone Diseases, Metabolic
;
Female
;
Follow-Up Studies
;
Humans
;
Hyperthyroidism
;
Iodine
;
Osteoporosis
;
Prevalence
;
Risk Factors
;
Thyroid Gland*
;
Thyroid Neoplasms*
;
Thyroidectomy
;
Thyrotropin
;
Thyroxine*
10.A Case of Double Right Coronary Artery with Arteriovenous Fisula.
Young Hwan SEO ; Gi Chang KIM ; Saerown CHOI ; Jung Sik MOON ; Seong Mi PARK ; Chang Keun LEE ; Dae Hyeok KIM ; Jun KWAN ; Keum Soo PARK ; Woo Hyung LEE
Journal of the Korean Society of Echocardiography 2004;12(2):101-103
Double coronary artery with coronary arteriovenous fistula is a very unusual anomaly and has not been reported in Korea. Coronary arteriovenous fistula consists of communication between one of the coronary arteries and a cardiac chamber or vein. It generally drains into the right ventricle, right atrium, coronary sinus, or pulmonary artery. It is being diagnosed with increasing frequency with combined use of coronary angiography and contrast echocardiography. In the present case, coronary angiography showed double right coronary artery with separated ostia. We confirmed that one of them drained into right ventricular chamber by contrast echocardiography performed after intraaortic contrast injection.
Arteriovenous Fistula
;
Coronary Angiography
;
Coronary Sinus
;
Coronary Vessels*
;
Echocardiography
;
Heart Atria
;
Heart Ventricles
;
Korea
;
Pulmonary Artery
;
Veins