Statistical observation was made on 117 cases of malignant tumors in the urinary tract who had been admitted to Department of the Urology, St. Mary's Hospital from January 1, 1966 to May 31. 1972. Statistical observation included age, sex, clinical manifestation, annual distribution, organ distribution and methods of operation. The results were as follows; 1. Male patients were more common than female patients, and most of them were over the age of 40 years. Hematuria was the most common symptom, and other symptoms were pain, mass and dysuria. Operations were performed in 79 patients, and remaining patients were treated with radiation, chemotherapy and hormone therapy. 2. The urinary bladder was the most commonly involved organ, and other organs were in order of kidney, prostate and penis. Histologically, transitional cell carcinoma in the bladder was the most common and next in order was of renal cell carcinoma, Wilms' tumor and squamous cell carcinoma of penis.
Carcinoma, Renal Cell ; Carcinoma, Squamous Cell ; Carcinoma, Transitional Cell ; Drug Therapy ; Dysuria ; Female ; Hematuria ; Humans ; Kidney ; Male ; Penis ; Prostate ; Urinary Bladder ; Urinary Tract* ; Urology ; Wilms Tumor

It is generally accepted that erythropoiesis is controlled by the erythropoietic stimulating factor (erythropoietin) which is believed being produced in the kidney. Among the various causes. hypoxia is one of the most potent one for the stimulation of erythropoietin production in the kidney. This experiment was planned to determine the efficiency of the erythropoietin in the hydronephrotic kidney and the intact or disturbed liver function. Materials and Methods: The mongrel dogs weighing between 10 and 13 kg were used. Group A: A1: hydronephrosis due to bilateral ureteral ligation. A2: hydronephrosis due to bilateral ureteral ligation and testosterone injection. A3: hydronephrosis due to bilateral ureteral ligation and CCI4 intoxication. Group B: B1' bilateral nephrectomy. B2: bilateral nephrectomy and CCI4 intoxication. To observe the chemical constituents and erythropoietic activity blood sample were collected on 2, 4, 6. 8. 10th day after operation in the A group and 1, 2, 3. 4th day after operation in the B group. Chemical constituents were BUN, creatinine and electrolytes. Erythropoietic activity was determined by the incorporation of 59Fe into the red cells of mouse (DeGowin method). The results of the experiments were summarized as follows: 1. The hydronephrosis due to bilateral ureteral ligation induced increase of erythropoietic activities. 2. When testosterone was given in the group of the hydronephrosis due to bilateral ureteral ligation, erythropoietic activity was increased more than in the group of the hydronephrosis only. 3. The most prominent elevation of erythropoietic activities among any other group was confirmed when liver function was disturbed by CCl4 intoxication in the hydronephrotic animals. This marked elevation seemed to be due to the disturbance of the liver function which inactivated or destroyed erythropoietin. 4. Erythropoietin activity was decreased in the group of bilateral nephrectomy. 5. Erythropoietin activity was much less in the bilateral nephrectcmized group when liver was damaged by CCI. injection. The erythropoietic stimulation was ineffective in the nephrectomized animals. 6. Testosterone injection decreased the BUN and creatinine level in the uremic animals due to nephrectomy. 7. Pathological findings revealed mild hydronephrotic changes in the group of ureteral ligation by. testosterone injection, and mild degree of necrosis and severe fibrosis in the interstitial tissue of the kidney, and fatty changes and focal central necrosis of the liver due to CCl4 injection.
Animals ; Anoxia ; Creatinine ; Dogs ; Electrolytes ; Erythropoiesis ; Erythropoietin* ; Fibrosis ; Hydronephrosis ; Kidney ; Ligation* ; Liver ; Mice ; Necrosis ; Nephrectomy* ; Testosterone ; Ureter*

A case of intussusception of a ureter due to a ureteral polyp was observed. Ureteral intussusception have been exceedingly rare, and very few reference to this condition can be found in the medical literature. The author have report a 39 years old female of a case of intussusception of the ureter associated with a benign polyp. The author have performed satisfactory conservative treatment. The patient was entirely recovery and has remained in excellent health since.
Adult ; Female ; Humans ; Intussusception* ; Polyps* ; Ureter*

A vesicovaginal fistula is a distressing complication which may follow hysterectomy and other extensive pelvic operation. Maligntncies of the uterin cervix or bladder may predispose to erosion and vesicovaginal fistula or such fistulas may occur as a result of extensive radiation therapy. Childbirth, particularly involving prolonged labor with potential necrosis of the vesico vaginal septum or complicated delivery with trauma may also induce a vesicovaginal fistula. In this experience the most common cause of vesicovaginal fistula resulting from surgery was total abdominal hysterectomy. Diagnosis of vesicovaginal fistula is usually made when appearance of methylene blue in the vagina after instillation of the dye into the bladder and further confirmed the presence and definitive localization of the fistula with cystoscopic examination. The operative procedures, the authors utilized were suprapubic transvesical closure in 8 cases, vaginal closure in two cases, and transabdominal approach in one case. The bladder was opened at the dome and then stay sutures were made at 1.0cm from the fistula margin. Then, the fistulous tract was excised making a lateral margin wide enough to leave viable tissue for subsequent closure. Vaginal wall and bladder wall closure were carried out in whole layer using interrupted 2 zero chromic suture. In one case of large fistula with high opening, the patient was underwent transabdominal method interposing a peritoneal flap between vagina and bladder wall. A urethral catheter was placed for 10 to 12 days postoperatively. In 5 cases of ureterovaginal fistula, one patient required the nephrectomy because of pyonephrosis, 2 patients refused further medication, one had ureteral reimplantation and another patient had psoas hitch and Boari operation. The following conclusions were obtained. 1. The most common cause of vesicovaginal fistula was the complication of total hysterectomy. 2. The diameter of fistulous tract was ranging from 1 to 10 mm. 3. For the repair of vesicovaginal fistula transvesical approach were 8 out of in 13 case, vaginal route in 2 cases, intraabdominal approach using a peritonal flap in one case. 4. Urethral catheter had been placed postoperatively was removed on the 12th postoperative day in most cases. Ureteral splint catheter was also placed for 8 to 10 days postoperatively. 5. 12 out of 14 cases, urinary vaginal fistulas were successfully closed on the first surgical attempt and one case healed on the second attempt. One case failed because of infection at the area of closure.
Catheters ; Cervix Uteri ; Diagnosis ; Female ; Fistula ; Humans ; Hysterectomy ; Methylene Blue ; Necrosis ; Nephrectomy ; Parturition ; Pyonephrosis ; Replantation ; Splints ; Surgical Procedures, Operative ; Sutures ; Ureter ; Urinary Bladder ; Urinary Catheters ; Vagina ; Vaginal Fistula* ; Vesicovaginal Fistula

Protermycin, the first molecular synthetic of tetracycline and chloramphenicol, has been given trial in 28 patients: acute gonococcal urethritis 10, nongonococcal urethritis 7, acute cystitis 6, chancroid 1 and postoperative cases 4. The doses ranged from 300 to 600 me daily. From this study, it was found that Protermycin proved itself to be most effective in nongonococcal urethritis which could not be treated satisfactorily by other antibiotics. Of 28 cases, 25 showed good result. The remaining 3 cases failed to respond.
Anti-Bacterial Agents ; Chancroid ; Chloramphenicol ; Cystitis ; Humans ; Tetracycline ; Urethritis

A clinical case of huge hemangioma of the left kidney is reported. The pathologic findings are described. A considerably greater incidence of left kidney involvement was found in review of the literature, including our case. The present case is the eighty-eight such occurrence recorded.
Hemangioma* ; Incidence ; Kidney*

No abstract available.

The parathyroid cyst is a relatively uncommon disease and usually identified during the operation for a presumed thyroid mass. Thirteen cases of parathyroid cyst (2 males, 11 females) treated from 1981 to 1993 were reviewed. Ages ranged from 17 to 59 years(mean, 41 years). Gross measurement of the tumor size varied from 1.0 to 10.0 cm in diameter with a mean of 4.8cm. All of the 13 patients presented with a chief complaint of painless anterior cervical mass. Only one complained of mild symptom of dyspnea and voice change due to huge cyst in paratracheal space. No functional cyst was identified. Diagnostic studies included ^99mTc thyroid scan (n=11), ultrasonography (n=10), computerized tomography (n=4) and fine needle aspiration(FNA) (preoperative, n=4; intraoperative, n=3). All diagnostic precedures but needle aspiration were nonspecific. Cysts were found in right inferior parathyroid(n=4), left inferior parathyroid (n=7), or anterior superior mediastinum (n=2). The FNA of the cyst contents revealed watery clear fluid with elevated parathyroid hormone level and was diagnostic in each cases. Four patients were treated initially with needle aspiration, of which only one patient was successful, and 3 patients who were unsuccessful to needle aspiration and the remaining 9 were effectively treated with surgical extirpation. Our experience suggested that needle aspiration may be of significant help in diagnosis and treatment of parathyroid cyst, but most of the patient could be treated successfully by surgical extirpation with an excellent chance for curability.
Biopsy, Fine-Needle ; Diagnosis ; Dyspnea ; Humans ; Male ; Mediastinum ; Needles ; Parathyroid Hormone ; Thyroid Gland ; Ultrasonography ; Voice

A clinical evaluation was performed on 7 patients of neurogenic bladder who underwent T.U.R. or T.U.R. with external sphincterotomy. All patients were indwelling Foley catheter from 7 months (minimal) to 2 and 1/2 years(maximal), were unable to self-voiding and their residual urine was over 100cc. The following conclusions were obtained: 1) 3 patients underwent T.U.R. but T,U.R. and external sphincterotomy was performed in 4 patients. 2) Of 7 patients, satisfactory result was obtained in 5 patients, but 2 patients obtained unsatisfactory result.
Catheters ; Humans ; Urinary Bladder, Neurogenic*

Renal angiogram offers valuable information in evaluating the patients with renal tumor, renal tuberculosis, polycystic kidney, hematuria, and renovascular hypertension. The author observed themorphological findings of renal disease, such as renal tumor, renal tbc, and polycystic kidney by selective renal angiography. A clinical evaluation were performed 36 patients of selective renal angiography which were done from 1972 to 1975. The result were as follows: Of 36 patients, comparison in clinical diagnosis with selective renal angiographic diagnosis. 1) Cases of correct clinical diagnosis with I.V.P. were 21 cases. 2) Cases of incorrect clinical diagnosis with I.V.P. were 3 cases. 3) At all, 12 cases were confirmed by renal angiography.
Angiography* ; Diagnosis ; Hematuria ; Humans ; Hypertension, Renovascular ; Polycystic Kidney Diseases ; Tuberculosis, Renal