No abstract available.

Lichenoid drug eruption is lichenoid skin eruptions caused by certain drugs and compounds, and can be identical or similiar to lichen planus. A 75-year-old woman who had taken antituberculosis medication(INH, ethambutol, rifampin) for 4 months developed pruritic generalized erythematous papular eruptions on the trunk and extremities, alopecia and nail dystropy. Histopathologic findings were hyperkeratosis, hypergranulosis, hyc rophic degenaration of basal layer, band like lymphohistiocytic infiltration in the upper dermis and perivascular lymphohistiocytic infiltration in the deep dermis. She was treated with systemic corticosteroid, and then skin lesion were slightly improved. After termination of antituberculosis medication, skin lesions were markedly improved with residual hyperpigmentation. Alopecia and nail dystrophy were also improved.
Aged ; Alopecia ; Dermis ; Drug Eruptions* ; Ethambutol ; Extremities ; Female ; Humans ; Hyperpigmentation ; Lichen Planus ; Skin

BACKGROUND: In tinea pedis, the response of treatment and prognosis are different according to clinical types. Positivity in KOH mount and causative agent in culture are also different. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycologic findings of tinea pedis according to the clinical type. METHODS: A clinical and mycological study was conducted with 97 cases of tinea pedis among out patients examined for 7 months from June 1994 to December 1994 at Yeungnam University Hospital and Catholic Skin Clizic, Taegu, Korea. RESULTS: 1. Age distribution showed patients in their fourth decade to be most common. The ratio of male to female was 1.2: 1. The distribution of patients by clinical type was interdigital type, interdigital combined with hyperkeratotic type, interdigital combined with vesicular type, hyperkeratotic type, and hyperkeratotic combined with vesicular type, in descending order. One to five years was the most comrrion duration of tinea pedis. Duration of tinea pedis was the shortest in the vesicular type, otherwis was longer in hyperkeratotic type. Rate of family history of tinea pedis was 54.6%. The larger the size of family was, the higher the positivity in family history. The rate of coexistent dermatiophytosis with tinea pedis was 39.1%, and tinea unguium was the most common one. 2. The isolated dermatophytis were T. rubrum, 90.7%, T. mentagrophytes, 7.2%, and T. rubrum rnixed with T. mentagrophytes, 2.1%. T. rubrum showed an even distribution in all clinical types of tinea pedis whereas T. mentanophytes was isolated only in the interdigital type, vesicular type, and interdigital combined with vesicular type. T. rubrum mixed with T. mentagrophytes was isolated in the interdigital combine with vesicular type. Distribution of dermatophytes was relatively even arnong the age groups. T. rubrum showed a relatively even distribution in duration of tinea pedis, but T. mentagrophytes was isolated in tinea pedis with shorter duration.
Age Distribution ; Arthrodermataceae ; Daegu ; Female ; Humans ; Korea ; Male ; Onychomycosis ; Outpatients ; Prognosis ; Skin ; Tinea Pedis* ; Tinea*

Angiosarcoma is a rare malignant vascular tumor of endothelial cell origin, Cutaneous angiosarcoma usually occurs on the scalp and face of the elderly and most frequently in the sixth and seventh decade. We presented a case of angicisarcoma in a 70 year old woman. The patient had a well-demarcated, 3 x 3cm sized, dark brownish-colored, ulcerative nodule on the vertex with hemorrhagic bulla on the right. temporal scalp. Histopathologic examination of the nodule showed a well differentiated tumor with irregular anastomosing scular channels lined by atypical endothelial cells in the dermis and subcutaneous fat. Immunohistochenlical study for factorVlll-related antigen was partially positive in tumor channels. She was treated by wide surgical excision but she expired 5 months after discharge from the hospital.
Aged ; Dermis ; Endothelial Cells ; Female ; Hemangiosarcoma* ; Humans ; Scalp ; Subcutaneous Fat ; Ulcer

No abstract available.
Antifungal Agents* ; Trichophyton*

KOH examination is a simple, rapid and diagnostic procedure to confirm dermatophytic infections. It is important to select a proper examination site of the lesion. To determinate the proper examination site of the lesion, mycologic studies were done with multiple specimens collected from the center, margin and out of margin of the ring-shaped dermatophytic skin lesion on the 58 patients. The results were as follows. Positive rate of KOH wet smear was 94.8% at the center and 100% at the margin of the lesions, 22.4% at the 1 cm and 5.2% at the 2 cm out of the lesions. The more hyphae were found in the lesion, the more hyphae were found out of the lesion. Culture was done on the Sabouraud's glucose agar from the highest KOH positive area and the positive culture was 48 strains (82.8%) of 58 patients. These findings suggested that the ring-shaped active margin was the best site to examine mycologic studies.
Agar ; Glucose ; Humans ; Hyphae ; Skin*

We report a case of kerion celsi caused by Trichophyton verrucosum in a 4-year-old male. He presented painful, tender, indurated, boggy masses discharing pus on the vertex and occiput. Kerion celsi caued by T. verrucosum was diagnosed by the characteristic gross and microscopic findings of the colony on the Sabourauds glucose. agar. The possible source of infection was searched and wq found that he raised the cattles in his house. They had multiple, scaly, whitish plaques on the skin and T. verrucosum was identified from the hairs of the lesions. He had been treated with griseofulvin and prednisolone, and all lesions were cleared leaving partial alopecia in 2 months.
Agar ; Alopecia ; Child, Preschool ; Glucose ; Griseofulvin ; Hair ; Humans ; Male ; Prednisolone ; Skin ; Suppuration ; Tinea Capitis* ; Trichophyton*

BACKGROUND: Tinea faciale usually has been classified as tinea corgoris. Recently it has often been classified as a seperate disease recently because of its various clinicel pesentations. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycological findings of tinea faciale, METHODS: Clinieal and mycological study was done with 42 eases of tinea faciale among out-patients examined for eight years from January 1985 to December 1992 at Yeungnam University Hospital, Taegu, Korea. RESULTS & CONCLUSION: 1. The average of annual distribution of patients was five and there a as no significant difference according to year. The age distribution of patients was highest under age 10(33.4%). The ratio of male to female patient was 3.1: 1. Monthly or seasonal distribution if patients was not significantly different. 2. Of 42 cases, causative organisms were isolated in 31 cases. They are Trichophyton(T.) rubrum in 19 cases (61.3%), Microsporum(M.) canis in 6 cases (19.4%), T. mentcgrophytes in 5 cases (16.1%) and M. gypseum in 1 case(3.7%) in tbe order of decreasing frequncd M. canis was the main causative organisrn in children under age 10. In the age group after 10, T. rubrum was predominated. T. rubrum infection was most frequently seen in spring, T. mentagrphates infection was seen more in winter and M. canis infectior in autumn. 3. Classic annular types were seen most frequently in the cases caused by T. rubrum and T. mentagrophytes. Papular types were seen most commonly in the case caused by M. canis. Multiple facial lesions were seen in T. rubrum infection (2 cases) and Of canis infection (1 case). Tinea faciale simulated several other dermatoses. These were contact, dermatitis, lupus erythematosus, photosensitive dermatosis, rosacea, granuloma annulare and acne. Of these, tinea faciale simulated contact dermatitis most frequently. Coexisting fungal infections were found in 7 patients and tinea corporis was most frequently present. Topical antifungsl agent was tried alone in 22 cases, and topical and systemic antifungal agent were combined in 20 cases.
Acne Vulgaris ; Age Distribution ; Child ; Daegu ; Dermatitis ; Dermatitis, Contact ; Female ; Granuloma Annulare ; Humans ; Korea ; Male ; Outpatients ; Rosacea ; Seasons ; Skin Diseases ; Tinea*

BACKGROUND: Tinea faciale usually has been classified as tinea corgoris. Recently it has often been classified as a seperate disease recently because of its various clinicel pesentations. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycological findings of tinea faciale, METHODS: Clinieal and mycological study was done with 42 eases of tinea faciale among out-patients examined for eight years from January 1985 to December 1992 at Yeungnam University Hospital, Taegu, Korea. RESULTS & CONCLUSION: 1. The average of annual distribution of patients was five and there a as no significant difference according to year. The age distribution of patients was highest under age 10(33.4%). The ratio of male to female patient was 3.1: 1. Monthly or seasonal distribution if patients was not significantly different. 2. Of 42 cases, causative organisms were isolated in 31 cases. They are Trichophyton(T.) rubrum in 19 cases (61.3%), Microsporum(M.) canis in 6 cases (19.4%), T. mentcgrophytes in 5 cases (16.1%) and M. gypseum in 1 case(3.7%) in tbe order of decreasing frequncd M. canis was the main causative organisrn in children under age 10. In the age group after 10, T. rubrum was predominated. T. rubrum infection was most frequently seen in spring, T. mentagrphates infection was seen more in winter and M. canis infectior in autumn. 3. Classic annular types were seen most frequently in the cases caused by T. rubrum and T. mentagrophytes. Papular types were seen most commonly in the case caused by M. canis. Multiple facial lesions were seen in T. rubrum infection (2 cases) and Of canis infection (1 case). Tinea faciale simulated several other dermatoses. These were contact, dermatitis, lupus erythematosus, photosensitive dermatosis, rosacea, granuloma annulare and acne. Of these, tinea faciale simulated contact dermatitis most frequently. Coexisting fungal infections were found in 7 patients and tinea corporis was most frequently present. Topical antifungsl agent was tried alone in 22 cases, and topical and systemic antifungal agent were combined in 20 cases.
Acne Vulgaris ; Age Distribution ; Child ; Daegu ; Dermatitis ; Dermatitis, Contact ; Female ; Granuloma Annulare ; Humans ; Korea ; Male ; Outpatients ; Rosacea ; Seasons ; Skin Diseases ; Tinea*

No abstract available.
Thyroid Diseases* ; Thyroid Gland*