No abstract available.
Child* ; Estradiol* ; Humans ; Testosterone*

No abstract available.
Endoscopy ; Gastrointestinal Hemorrhage*

No abstract available.
Breast* ; Milk, Human*

During the course of infectious mononucleosis, intake of ampicillin and its analogues such as amoxicillin may cause hypersensitivity skin rashes. We report herein a case of ampicillin induced skin rash in a 41-year-old female patient with infectious mononucleosis. Infectious mononucleosis was confirrned by datetion of IgM antibody against Epstein-Barr(EB) viral capsid antigen(VCA) in her serum. During the icuteillness, she taked ampicillin for 3 days, and 1 week after the intake of ampicillin, a genertliz:d erythernatous and purpuric maculopapualr eruption developed. Physicians should be careful not to use ampicillin and its analogue if batients are suspected to be infected with EB virus as ampicillin induces severe skin rashes in patients with infectious mononucleosis.
Adult ; Amoxicillin ; Ampicillin* ; Capsid ; Exanthema* ; Female ; Humans ; Hypersensitivity ; Immunoglobulin M ; Infectious Mononucleosis* ; Skin*

Characteristic dermatoglyphic patterns are found on the volar aspect of the skin of the primates including, man, apes, monkeys and some kinds of marsupiaIs. It is the delieate continuous or discontinuous and sometimes interrupted or branched, variable shaped configuration of ridged skin patterns, which is composed of the unit pattern of arch, loop and whorl. It is characteristically unique for any individuals so it has been used popularly as a convenient method of personal ideatification or for use in studies of inheritance epecially i the field of Iegal medicine. Besides that, there are statistieal differences between left and right finger, males and femals and different races. Of particular interest is the fct the distortion of the dermatoglypbic patterns occur in relation to cbromosomal aberrations, for exarnple, in mongolism,Klinefelter's syndrome and Turner'e syndrome. In addition to that, dermatoglyphic features may prove and aid to diagnree in dermatology, such as, in alopecia areata, psoriasis and leprosy. Thus, authors studied on the dermatoglyphic pattern types in the 234 cases of healthy normal males, 44 male psoriatic patients and 58 male alopecia areata patients during the period of 10 months from Novernber, 1977 to August, 1978, The resulta are as follows: A. Psoriasis 1. In the analysis of the total fingertip ridges, there are significant differences (p<0.01) between the alopecia areata (141.66+/-8.36) and the control group (152.93+/-9.50). 2. A significant statistical difference between the psoriasis and the control group does not exist with respect to the pattern intensity. 3. In the incidence of simian lines, the psoriatic patients (15.91%) showed more incidence rate than those of control group (8.98%). 4. With respect to the proportional distance (mm.) between the distal flexion crease of the wrist to the base of the middle finger with the distance (mm.) of the same point of the wrist to the axial triradius, a significant statistical difference (p<0.05) between the left hands of the control gorup (15.24+/-0.37%) and, those of psoriasis (17.35+/-1.01%) was existed. 5. As for the and angle, there is no significant differences between the control and psoriasis group. 6. There is no statistical differences in view point the pattern types between the psoriasis and the control group, however in psoriasis group, double whorls are decreased than those of control gorup (6.8%). B. Alopecia areata 1. In the analysis of the total fingertip ridges, there is significant difference (P<0.01) between the Alopecia areata (138.40+/-5.03) and the control group (152.93+/-9.50). 2. A significant statistical differences (P<0.005) between the alopecia areata (14.193+/-0.487) and the control group (14.728+/-0.182) exist with respect to the pattern intensity. 3. In the incidence of simian lines, the alopecia areata patients (3.44%) showed lower incidence rate than those of control group (8.98%). 4. With respect to the proportional distance (mm.) between the distal flexion crease of the wrist to the base of the middle finger with the distance (mm.) of the same point of the wrist to tbe axial triradius, a significant statistical difference(p<0.05) between the left hands of the control group (15.24+/-0.37%) and those of alopecia areata (16.66+/-0.70%) was existed. 5. As for the and angle, it is increased significantly (P<0.01) in both hands of alopecia areata, especially in the right hands of alopecia areata, it is increased about twice that of control group. 6. There is no statistical differences in the pattern types between alopecia areata and control group, however in alopecia areata patients, whorls in the right index finger are decreased (39.66%) than those of control gorup (50.16%), Whereas loops in the right index finger are more freguently found (50%) than those of control group (37.44%).
Alopecia Areata* ; Alopecia* ; Continental Population Groups ; Dermatoglyphics* ; Dermatology ; Fingers ; Hand ; Haplorhini ; Hominidae ; Humans ; Incidence ; Leprosy ; Male ; Primates ; Psoriasis* ; Skin ; Wills ; Wrist

Stasis eczema is one of the important skin manifestations caused by venous stasia. dueto vascular disturbances. Until now a few casses of stasis eczema accornpanied with inferior vena cava obstruction were reported in the literatures. The patient, 31-year old barber, has been suffered from right upper guadrant abdominal pain and tenderness for 6 years, and had dark brownish mottled scaly eczematoid patches of both lower extremitiea for 6 yrs. Inferiorvenacavogram through the right fernoral vein showed complete obstruction of inferior vena cava above the level of T10, and well developed several collateraI veins. Findings of skin biopsy on the right ankle joint area revealed moderate acanthosis, increased pigrnentation of the basal cell layer in the epidermis, capillary proliferation and hemosiderin granules in the dermis, that is consistent with stasis eczema. Possible etiological factor of inferior vena cava obstruction waa discussed and also reviewed with literatvre.
Abdominal Pain ; Adult ; Ankle Joint ; Biopsy ; Capillaries ; Dermis ; Eczema* ; Epidermis ; Hemosiderin ; Humans ; Skin ; Skin Manifestations ; Veins ; Vena Cava, Inferior

Dermatoglyphics has been studied in various diseases including mongolism, ruhella syndrome, congenital heart disease, selected neurologic diseases and other disorders. However, reports of derrnatoglyphic studies in patients with leprosy have not been evcountered a lot. Although Ieprasy is an infectious disease due to the hfycobacterium leprae, the hereditary susceptibility of the host to the organism is proposed as an additional predisposing factor. Thia concept has been proposed to reconcile the low incidence of lisease among large numbers of contacts. Most reports delving into the role of heredity in leprosy have been related ta epidemiological studies. Prasad and Mohamad suggest, on the basis of data related to rnultiple patient families, that the acquisition of leprosy may be determined genetically on the assumption of incomplete dominance of genes; on the other hand, Spickett suggested that if there is any genetic effect, it is but a component af the familial effect. This study of dennatoglyphics in 77 male leprosy patients was undcataken to determine if there might be significance in the analysis of dermal patterns af the hands as related to the hereditary susceptibility of individuals to the disease comparing with those of 234 healthy Korean soldiers. Results are as follows: 1. In the analysis of the total fingertip ridges, there is significant difference (P<0.01) between the leprosy (137.66+4.7) and the control group (152.93+9.50). 2. A aignificant statistical difference between the leprosy and the control group (14.73+2.79) does not exist with respect to the pattern intensity, however that af the borderline group of leprosy (12.00+5.09)is decreased (P<0.025). 3. In the incidence of simian lines, the leprosy group (5.20%) shows lower incidence rate than that of control group (8.98%). 4. As for the a-b ridge count, it is decreased significantly (P<0.05) in the left hand of leprosy group (34.71+0.87) than that of the eontrol group (37.11+0.52), Also there is significant difference(P<0. 05) in the right hands of tuberculoid type of leprosy (34.64+1.38). 5. With respect to the propoetional distance (mm.) between the distal flexion crease of the wrist to the base of the middle finger with the distance (mm.) of the same point of the wrist to the axial triradius, a significant statistical difference between the leprosy and the control group does not exist, but significantly longer distance (mm.) exists in the tuberculoid type of leprosy (P<0.05). 6. No significant fingertip pattern differences are noted between the leprosy and the control group.
Causality ; Communicable Diseases ; Dermatoglyphics* ; Down Syndrome ; Epidemiologic Studies ; Fingers ; Hand ; Heart Defects, Congenital ; Heredity ; Humans ; Incidence ; Korea* ; Leprosy* ; Male ; Military Personnel ; Wrist

The courses of the progression in the fibrous dysplasia are characterized by asymptomatic progression or spontaneous regression in some cases after the growth has ceased and the aims of treatment for a fibrous dysplasia are prevention of the pathologic fractures and correction of the deformities. The osteogenic potentiality of the cambium layer in the periosteum and the beneficial effect on the osteogenesis of the impregnating bone graft with autologous red marrow are well documented. We experienced an extensive fibrous dysplasia with cortical thinning and pathologic fracture and it was managed with subperiosteal combined xenograft of Kiel bone with autologous red marrow for the induction of cortical thickening and prevention of the pathologic fractures because of the inoperability of curettage due to extensive lesion over the entire femur, limitations in obtaining large amount of autogenous cancellous bone for the graft and lack of the facilities of the bone bank. This subperiosteal composite xenograft with autologous red marrow for a fibrous dysplasia gave an excellent result of a remarkable cortical thickening and we think this can be a type of management for a entensive fibrous dysplasia. So we are reporting this case with bibliographic reviews.
Bone Banks ; Bone Marrow ; Cambium ; Congenital Abnormalities ; Curettage ; Femur ; Fractures, Spontaneous ; Heterografts ; Osteogenesis ; Periosteum ; Transplants

Wide resection is an acceptable alternative to amputation for the management of primary sarcomas of the long bones or pelvis. The resected bone can be debrided of gross tumor tissue, autoclaved, and than replaced to reconstruct the limb anatomically. The procedure can be combined with prosthetic reconstruction of adjacent joints with sufficient strength to allow early unprotected weight-bearing. We had an experience of a large segmental defect in the shaft of the humerus after wide resection due to.a low grade malignant chondrosarcoma without extension to the surrounding soft tissues and this case had been managed by reimplantation after autoclaving the locally resected segment and autogenous iliac bone graft with a sound union and the favorable functional outcomes. So we are reporting this case with bibliographic reviews as a possible method of reconstruction for the management of the segmental defect which was produced by a local resection for a low grade malignancy.
Amputation ; Chondrosarcoma ; Extremities ; Humerus ; Joints ; Methods ; Pelvis ; Replantation ; Sarcoma ; Transplants ; Weight-Bearing

Implant materials, for examples, plaster of Paris, Bone cement and ceramics which are used experimentally to regain shape and function, act as a scaffold for bone growth and contribute to the healing processes at bone defect developed by trauma, infection and other causes. Therefore, the effect of plastei of Paris on the bone defects of adult rabbits may be an interesting subject, particularly in the orthopedic field. The authors carried out an experiment to study the effect of plaster of Paris on the bone defect, using 30 adult rabbits weighing fmm 3000-3500 gm, which were divided into 3 main gmups. (Each group was composed of 10 adult rabbits.). In Group 1, which was the control group, made a defect at the proximal metaphysis of the tibia, 6 mm×6 mm×6 mm in size, using a drill bit and filled by hematoma spontaneously. In Group II and Group IU, a defect was also made by the same method as in Group I and a piece of Gelfoam or plaster of Paris was inserted into the bone defect respectively. Then we studied the healing processes of the bone defect by sacrifying animals of each group at 6th and 12 th week after operation. The results of this experiment were as follows. 1. New bone formarion in the bone defect was poor in group I and Gmup Il, but it was good in Group III. 2. The plaster of Paris, filling into the defect, was absorbed and removed from the site of implantation continuously and stimulated the new bone formation. 3. The Gelfoam in Group II was more rapidly absorbed than plaster of Paris and didn't stimulate the new bone formation.
Adult ; Animals ; Bone Development ; Calcium Sulfate ; Ceramics ; Gelatin Sponge, Absorbable ; Hematoma ; Humans ; Methods ; Orthopedics ; Osteogenesis ; Rabbits ; Tibia