No abstract available.
Fascia* ; Foot* ; Free Tissue Flaps* ; Hand* ; Rabeprazole*

No abstract available.
Blood Glucose* ; Glucose* ; Humans ; Infant, Newborn*

The postnatal development of somatostatin [SOM]- and neuropeptide Y[NPY]- immunoreactive[ir] neurons were examined in rat cerebral cortex considering their coexistence in cortical neurons. Using double immunohistochemical staining for SOM and NPY with diaminobenzidine and benzidine dihydrochloride as chromogens, we subdivided immunoreactive cells into double-labeled SOM/NPY-, SOM only-, and NPY only-ir neurons. Interestingly, SOM/NPY- and SOM only-ir neurons were detectable even at the day of birth, in contrast to NPY only-ir cells which first appeared in most cortices from two weeks of age. The morphological features of double-labeled SOM/NPY neurons were not identical to those SOM only- and NPY only-ir neurons. No apparent changes in the shape and size of single-labeled neurone occurred with age ; throughout their postnatal life they were round and ovoid, had a thin rim of perinuclear cytoplasm, and short processes. In contrast, the features of SOM/NPY-ir neurons were not consistent during postnatal life. By day P7, these neurons showed immature features ; they began to show more advanced neuronal characteristics by week P2, when they had a larger and more intensely-stained cytoplasm. In addition, their processes were longer, thicker and more complex than at earlier ages. At this age, SOM/NPY-ir somata were close to their maximum size. From week P4, they became smaller and were lightly labeled. SOM/NPY-ir somata were larger than SOM only- and NPY only-ir somata at and after two weeks of age. The present results showing different postnatal maturation patterns such as time of appearance and morphological features suggest that double-labeled SOM/NPY and single-labeled neurons might be different populations regulated by different mechanisms in their development, and with different functional properties during development.
Animals ; Cerebral Cortex* ; Cytoplasm ; Neurons* ; Neuropeptide Y* ; Neuropeptides* ; Parturition ; Rats* ; Somatostatin*

Pedicled bone flap raised from the volar aspect of lower end of the radius, pedicled by the pronator quadratus has been used for the treatment of scaphoid nonunion and Kienbock's disease. From July 1991 to Jan. 1992, authors performed this procedures for 3 cases of Kienbock's disease. Patients were 2 cases in the left hand, l case in the right hand. There was no critial trauma history. Age at operation were 25, 37 and 57 years. All patients were in Stage I in 2 cases and stage II-A in 1 case of Lichtman's radiologic classification. Preoperative grip powers were 11%, 38%, 63% and pinch powers were 20%, 41%, 61% of that of normal opposite hand. Follow up periods were 28, 31 and 33 months. At last follow up roentgenographic finding shows no progression of necrosis of lunate, new bone formation, decreased sclerosis, and joint space were preserved in all cases. The fuctional results at the last follow up were as follows. Pain during motion was markedly diminished in all patients. Grip power were 57%, 89% and 96% and pinch powers were 68%, 83% and 100% of that of normal opposite hand with use of calibrated Jamar dynamometer which showes significant increase than preoperative state. The ranges of motion of wrist were as follows. Volar flexion were 40, 45 and 80 degree. Dorsiflexion were 10, 20 and 45 degree. Ulnar deviation were 10, 20 and 30 degree. Radial deviation were 10, 25 and 30 degree. This viable bone graft with blood supply gives very satisfactory clinical results.
Classification ; Follow-Up Studies ; Hand ; Hand Strength ; Humans ; Joints ; Necrosis ; Osteogenesis ; Osteonecrosis ; Radius ; Sclerosis ; Transplants ; Wrist

Finite Element Analysis ; Humans ; Mandible ; Stress, Mechanical

BACKGROUND: Studies on immunization in Korea mainly focus to the coverage rates in recipients. The attitudes of health-care providers regarding immunization are rarely evaluated. Therefore, to assess the pattern of vaccine administration by health-care personnel, the vaccine consumption in a university hospital was investigated. MATERIALS AND METHODS: The vaccine consumption in a university hospital during 2 months (September and October) in 2 years (2002 and 2007) was evaluated. September is representative of months when influenza vaccine is not available, whereas October is representative of months when influenza vaccine is available. These monthly data were summarized by departments and vaccines. RESULTS: Vaccine consumption over the 5-year period increased primarily because of the increased use of the influenza and tetanus-diphtheria (Td) vaccines in adults. In 2007, the most frequently administered vaccine during the influenza season was the influenza vaccine, followed by the Td vaccine. In the same year, the Td vaccine was the most frequently administered vaccine during the non-influenza season. Compared to 2002, there was a marked increase in the use of the hepatitis A virus (7-fold), Japanese encephalitis (6-fold), and pneumococcal polysaccharide (3-fold) vaccines in 2007; the Td, meningococcal, and pneumococcal protein-conjugated vaccines were not available in 2002. In adults, pneumococcal vaccination was increasingly prescribed concomitant with the increased influenza vaccination; a similar trend was not observed in children. The use of vaccines in most departments was confined to the influenza vaccine, and the majority of Td vaccine was consumed in the emergency department. As compared to the internal medicine and family medicine departments, fewer vaccines were prescribed by the neurology, surgical, and minor specialty departments, especially in the non-influenza season. CONCLUSION: Although vaccine consumption increased during the 5-year period, the increase was attributed to the increased consumption of the influenza vaccine. Promotion and education regarding the use of non-influenza vaccines are needed.
Adult ; Child ; Emergencies ; Encephalitis, Japanese ; Health Personnel ; Hepatitis A virus ; Humans ; Immunization ; Influenza Vaccines ; Influenza, Human ; Internal Medicine ; Korea ; Neurology ; Pharmacy Service, Hospital ; Seasons ; Vaccination ; Vaccines

BACKGROUND: Studies on immunization in Korea mainly focus to the coverage rates in recipients. The attitudes of health-care providers regarding immunization are rarely evaluated. Therefore, to assess the pattern of vaccine administration by health-care personnel, the vaccine consumption in a university hospital was investigated. MATERIALS AND METHODS: The vaccine consumption in a university hospital during 2 months (September and October) in 2 years (2002 and 2007) was evaluated. September is representative of months when influenza vaccine is not available, whereas October is representative of months when influenza vaccine is available. These monthly data were summarized by departments and vaccines. RESULTS: Vaccine consumption over the 5-year period increased primarily because of the increased use of the influenza and tetanus-diphtheria (Td) vaccines in adults. In 2007, the most frequently administered vaccine during the influenza season was the influenza vaccine, followed by the Td vaccine. In the same year, the Td vaccine was the most frequently administered vaccine during the non-influenza season. Compared to 2002, there was a marked increase in the use of the hepatitis A virus (7-fold), Japanese encephalitis (6-fold), and pneumococcal polysaccharide (3-fold) vaccines in 2007; the Td, meningococcal, and pneumococcal protein-conjugated vaccines were not available in 2002. In adults, pneumococcal vaccination was increasingly prescribed concomitant with the increased influenza vaccination; a similar trend was not observed in children. The use of vaccines in most departments was confined to the influenza vaccine, and the majority of Td vaccine was consumed in the emergency department. As compared to the internal medicine and family medicine departments, fewer vaccines were prescribed by the neurology, surgical, and minor specialty departments, especially in the non-influenza season. CONCLUSION: Although vaccine consumption increased during the 5-year period, the increase was attributed to the increased consumption of the influenza vaccine. Promotion and education regarding the use of non-influenza vaccines are needed.
Adult ; Child ; Emergencies ; Encephalitis, Japanese ; Health Personnel ; Hepatitis A virus ; Humans ; Immunization ; Influenza Vaccines ; Influenza, Human ; Internal Medicine ; Korea ; Neurology ; Pharmacy Service, Hospital ; Seasons ; Vaccination ; Vaccines

PURPOSE: To evaluate the pressure-lowering effects of selective trabeculoplasty versus these of Argon laser trabeculoplasty. METHODS: Fifteen eyes of 15 patients with primary open-angle glaucoma and ocular hypertension, all with IOPs over 30 mm Hg received SLT and 30 eyes of 30 patients with the same diagnosis were treated with ALT. Patients were evaluated after laser treatments at 1 hour, 1 day, 1 week, 1 month, and 3 months using slit lamp examinations and Goldmann applanation tonometry. RESULTS: At 3 months postoperative, the SLT group had a mean IOP of 16.9+/-4.2 mmHg with a mean reduction of 31.2+/-20.1%, while the ALT group had a mean IOP of 17.9+/-5.4 mmHg with a mean reduction of 26.3+/-23.3%. CONCLUSIONS: Selective trabeculoplasty and Argon laser trabeculoplasty are equally effective statistically in lowering IOP over a 3-month period (p=0.47). SLT has been shown to be safe and effective in lowering IOP.
Argon* ; Diagnosis ; Glaucoma, Open-Angle* ; Humans ; Manometry ; Ocular Hypertension ; Trabeculectomy*

PURPOSE: The aim of this study was to analyze the effects of transconjunctival lower blepharoplasty combined with the pinch skin excision technique. METHODS: This study followed 15 patients over a six-month period who had undergone transconjunctival lower blepharoplasty combined with the pinch skin excision technique. The follow-up period exceeded 6 months. After subconjunctival injection of local anesthetic, incisions of the conjunctiva and lower lid retractors were made. The exposed fat pads were excised by clamping, excising, and cauterizing the base of the pad. The conjunctiva was closed with a continuous 6-0 Vicryl suture. If there was mild skin excess, a pinch skin excision technique was used. RESULTS: There were no complications (i.e., lower eyelid retraction, ectropion, etc.). All 15 patients were satisfied with the final result. CONCLUSIONS: The transconjunctival lower blepharoplasty combined with the pinch skin excision technique in middle-aged patients with prominent lower eyelid fat and skin excess had lower complication rates and higher patient satisfaction than the transcutaneous approach.
Adipose Tissue ; Blepharoplasty* ; Conjunctiva ; Constriction ; Ectropion ; Eyelids ; Follow-Up Studies ; Humans ; Patient Satisfaction ; Polyglactin 910 ; Skin* ; Sutures

The reconstruction of foot remains difficult problem with many surgical modalities because foot has unique structure, insufficient local soft tissue and poor vascularity. The medial plantar island flap is capable of providing sensate and structurally similar tissue with single operative procedure. We reconstructed 5 cases of soft tissue defects on the foot by using medial plantar island flap(3 cases proximally- based, 2 cases distally-based) in diabetics. Successful soft tissue coverage was achieved on medial malleolus, dorsal midfoot, tendo calcaneus, and forefoot. The size of flap ranged from 3.5 x 3.0 cm to 6.0 x 4.0 cm. Follow-up ranged from 8 months to 26 months. All flaps survived without serious complication. All patients had protective sensation in daily activities and were able to ambulate in normal footwear. This paper demonstrates that medial plantar island flap with proximally and distally-based pedicle should be considered as a useful technique for reconstruction of soft tissue defect from ankle to forefoot.
Ankle ; Calcaneus ; Follow-Up Studies ; Foot ; Humans ; Sensation ; Surgical Procedures, Operative