Authors experienced five different cases of keratitis such as metaherpetic keratitis, bullous keratitis, chemical keratitis and superficial punctate keratitis have been markedly improved by subconjunctival injection of Tathion (30-50mg), a glutathion prepartion. All cases showed remarkable improvement with better visual acuity following the treatment. Especially it was another choice of treatment in persisting case of metaherpetic keratitis with parenchymal infiltration. No side effects have been observed during this procedure.
Keratitis* ; Visual Acuity

In search of the effect of air pollution on the eye, the authors examined ocular symptoms and diseases in both an urban(Seoul) and two rural populations (Suwon and Changsung). The Prevalence rate of ocular symptoms and diseases between 109 occupational drivers of more than 3 years career in Seoul area which is one of the air polluted urban areas and 150 populations in the two different rural areas as a control group were compared. The prevalence rate of ocular symptoms was 89% in Seoul, 10% in Suwon and 23% in Changsung area, and those of ocular diseases were 35%, 6% and 10% in the same areas, respectively. The prevalence rate of ocular symptoms and diseases is respectively 3 to 4 times more prevalent in occupational drivers than in the control groups. Many other etiologic factors such as occupation, labor condition, environmental stress or different way of living may influence the prevalence rate between the two groups, however, it would be presumed that the main causative factor to cause ocular symptoms and diseases is probably due to air pollution.
Air Pollution ; Gyeonggi-do ; Occupations ; Prevalence* ; Rural Population* ; Seoul

No abstract available.
Hemorrhagic Fever with Renal Syndrome* ; Humans ; Proteinuria*

Hypertrophic cardiomyopathy (HCMP) is characterized myofiber hypertrophy and structural remodeling with changes in the proportion of the muscular, vascular, and interstitial compartments. A study was done to determine the structural remodeling patterns and the role of microvasculature of hearts in HCMP. Forty-two postmortem hearts were analyzed including 14 from patients who died of HCMP (group 1), 8 patients with HCMP but who died from extracardiac causes (group 2), 10 patients with ischemic heart disease (group 3), and 10 normal adult hearts (group 4). Macro- and microscopic examination, immunohistochemical study using CD34 antibody, and morphometric studies using image analyzer were performed. Mean cardiac weight and wall thickness were significantly higher in the HCMP group. Myocardial hypertrophy, and a variety of myocardial disarray and fibrosis involved the whole area of the left ventricles with HCMP. The percentage areas of microvessels were 6.40 0.7 in group 1, 5.90 0.6 in group 2, 4.98 0.3 in group 3, 4.85 0.4 in group 4, respectively, and the numbers of microvessels were 198.0 20.7 in group 1, 230.0 22.3 in group 2, 211.7 11.2 in group 3, and 236.4 11.4 in group 4, respectively (mean SE). The percentage area of microvessels was significantly higher in group 1 than in other groups. However, the number of microvessels in that group was lower than in the other groups, although it was statistically insignificant. Since flow-dependent vasodilation is preserved in HCMP, we considered flow-dependent vasodilation the cause of the discrepancy between the area and the number of microvessels. Ischemic changes observed in chronic HCMP and related heart failure were considesed to be due to the relative deficiency of the coronary flow compared to the increasing cardiac mass.
Adult ; Cardiomyopathy, Hypertrophic* ; Fibrosis ; Heart ; Heart Failure ; Heart Ventricles ; Humans ; Hypertrophy ; Microvessels ; Myocardial Ischemia ; Vasodilation

The authors present a case of interstitial keratitis due to congenital syphilis in a 25-years old Korean army soldier, who had admitted to our Eye clinic at 2nd Feb. 68'. The patient may be present, such as interstitial keratitis, deafness and Hutchinson's teeth. Syphilitic interstitial keratitis is known as a rare case in recent time. A brief review of the related literatures is present.
Adult ; Deafness ; Humans ; Keratitis* ; Military Personnel ; Syphilis, Congenital*

No abstract available.
Breast Neoplasms* ; Breast*

The authors ana lysed statistically seventy-five cases of the eye injuries in childhood under the age of 20 years old during a full year of 1972. 1. Incidence of eye injuries under 20 years old was about 1.1% of total out-patients and 39.9% of total eye injuries. 2. The most common objects to the injury were iron pieces or iron made materials (24%) such as needle, nail, flying iron piece, toy, wire and bar etc. 3. The most common nature of eye injuries was traumatic cataract (14.2%) 4. Seasonally the high peak of injuries was in summer (33.3%) and winter vacation (30.7%) 5. Blindness(under20/200 of corrected VA) was occured finally in 10.8% of total 75 cases.
Cataract ; Diptera ; Eye Injuries* ; Humans ; Incidence ; Iron ; Needles ; Outpatients ; Play and Playthings ; Seasons ; Young Adult

Epithelial myoepithelial carcinoma is a rare tumor with slightly less than one percent of salivary gland neoplasm. Histologically, the carcinomas are characterized by a mixture of trabecular structure with outer myoepithelial cells and inner ductal cells, which are confirmed by electron microscopy and immunohistochemistry. Although this neoplasm exhibits high degree of cellular differentiation histologically, it is classified into low grade carcinoma because of its locally infiltrative, destructive growth pattern, and tendency to metastasize. We report a 45-year-old woman with epithelial-myoepithelial carcinoma arising from a submandubular gland, one of the most unusual locations.
Female ; Humans ; Immunohistochemistry ; Microscopy, Electron ; Middle Aged ; Salivary Gland Neoplasms ; Submandibular Gland

PURPOSE: The aim of this study was to detail clinical experiences with a new type of tension-free herniorrhaphy using the Prolene Hernia System (PHS) and analyze the system' usefulness. METHODS: We reviewed 48 cases of herniorrhaphy using PHS and 45 cases of conventional herniorrhaphy retrospectively by reviewing the medical records of patients undergoing either procedure between January 2000 and February 2005. RESULTS: There was no significant difference in the operation time (P=0.054) or the length of hospital stay (P=0.138) between the groups. However, the need for analgesic therapy in the PHS group was less than in the control group (P= 0.008). There were no serious postoperative complications, but wound complications occurred more often in the PHS group (6 seromas and 2 hematomas), and urinary retention occurred more frequently in the control group. The recurrence rate in the control group was 2.2% (1/45), but there were no recurrences in the PHS group for 46 months. CONCLUSION: Herniorrhaphy using the PHS is safe and effective as conventional surgery. It can be carried out under local anesthesia more easily, and it is less painful than the conventional surgery. We suggest that the PHS be widely adopted as a method of tension-free herniorrhaphy.
Anesthesia, Local ; Hernia ; Hernia, Inguinal ; Herniorrhaphy ; Humans ; Hydrogen-Ion Concentration ; Length of Stay ; Medical Records ; Polypropylenes ; Postoperative Complications ; Recurrence ; Retrospective Studies ; Seroma ; Urinary Retention

To delineate the clinicopathological features of diffuse axonal injury in patients with diffuse cerebral injury, we reviewed 19 cases from a series of 726 brain autopsies performed during a recent ten-year period. The criteria for inclusion were loss of consciousness for more than 6 hours in closed head injury patients, and no development of a space-occupying lesion within 7 days of injury. The injury was more prevalent in males(70.6%), and in patients aged between 10 and 50 years(82.4%). The main cause was traffic accident(82.4%), and the patients, Glasgow coma scale score on admission after injury was between 3 and 7. CT or MRI performed within the first 7 days of injury disclosed either one or combined focal lesions in the cerebral white matter, corpus callosum and brain stem in 66.7% of cases, and no identifiable lesion in 33.3%. Axonal swellings are the histologic hallmark of diffuse axonal injury in closed head trauma. In this study, careful brain dissection and neuropathologic studies demonstrated these swellings in all autopsy brains. The immunohistochemical stain for neurofilament proteins(68kD, 160/200kD) is the most sensitive marker of axonal swelling, especially when a patient survives more than 12 hours after injury. However, a neurofilament protein(160/200kD) is also expressed in a few normal pyramidal neurons and axial dendrites. Bielschowsky stain also clearly delineates axonal swellings in patients who have survived more than 2 days after injury. Cerebral edema and the appearance of amyloid body are easily identifiable by Luxol fast blue-PAS stain. In patients who survive for 6 months after injury, axonal swellings are hardly identifiable; about 25% of cases are diagnosed by neuropathologic examination only. The above data indicate that for the diagnosis of diffuse axonal injury, careful gross examination and neuropathologic studies are important.
Amyloid ; Autopsy ; Axons ; Brain ; Brain Edema ; Brain Stem ; Corpus Callosum ; Craniocerebral Trauma* ; Dendrites ; Diagnosis ; Diffuse Axonal Injury* ; Glasgow Coma Scale ; Head Injuries, Closed ; Head* ; Humans ; Magnetic Resonance Imaging ; Neurons ; Unconsciousness