Characteristic dermatoglyphic patterns are found on the volar aspect of the skin of the primates including, man, apes, monkeys and some kinds of marsupiaIs. It is the delieate continuous or discontinuous and sometimes interrupted or branched, variable shaped configuration of ridged skin patterns, which is composed of the unit pattern of arch, loop and whorl. It is characteristically unique for any individuals so it has been used popularly as a convenient method of personal ideatification or for use in studies of inheritance epecially i the field of Iegal medicine. Besides that, there are statistieal differences between left and right finger, males and femals and different races. Of particular interest is the fct the distortion of the dermatoglypbic patterns occur in relation to cbromosomal aberrations, for exarnple, in mongolism,Klinefelter's syndrome and Turner'e syndrome. In addition to that, dermatoglyphic features may prove and aid to diagnree in dermatology, such as, in alopecia areata, psoriasis and leprosy. Thus, authors studied on the dermatoglyphic pattern types in the 234 cases of healthy normal males, 44 male psoriatic patients and 58 male alopecia areata patients during the period of 10 months from Novernber, 1977 to August, 1978, The resulta are as follows: A. Psoriasis 1. In the analysis of the total fingertip ridges, there are significant differences (p<0.01) between the alopecia areata (141.66+/-8.36) and the control group (152.93+/-9.50). 2. A significant statistical difference between the psoriasis and the control group does not exist with respect to the pattern intensity. 3. In the incidence of simian lines, the psoriatic patients (15.91%) showed more incidence rate than those of control group (8.98%). 4. With respect to the proportional distance (mm.) between the distal flexion crease of the wrist to the base of the middle finger with the distance (mm.) of the same point of the wrist to the axial triradius, a significant statistical difference (p<0.05) between the left hands of the control gorup (15.24+/-0.37%) and, those of psoriasis (17.35+/-1.01%) was existed. 5. As for the and angle, there is no significant differences between the control and psoriasis group. 6. There is no statistical differences in view point the pattern types between the psoriasis and the control group, however in psoriasis group, double whorls are decreased than those of control gorup (6.8%). B. Alopecia areata 1. In the analysis of the total fingertip ridges, there is significant difference (P<0.01) between the Alopecia areata (138.40+/-5.03) and the control group (152.93+/-9.50). 2. A significant statistical differences (P<0.005) between the alopecia areata (14.193+/-0.487) and the control group (14.728+/-0.182) exist with respect to the pattern intensity. 3. In the incidence of simian lines, the alopecia areata patients (3.44%) showed lower incidence rate than those of control group (8.98%). 4. With respect to the proportional distance (mm.) between the distal flexion crease of the wrist to the base of the middle finger with the distance (mm.) of the same point of the wrist to tbe axial triradius, a significant statistical difference(p<0.05) between the left hands of the control group (15.24+/-0.37%) and those of alopecia areata (16.66+/-0.70%) was existed. 5. As for the and angle, it is increased significantly (P<0.01) in both hands of alopecia areata, especially in the right hands of alopecia areata, it is increased about twice that of control group. 6. There is no statistical differences in the pattern types between alopecia areata and control group, however in alopecia areata patients, whorls in the right index finger are decreased (39.66%) than those of control gorup (50.16%), Whereas loops in the right index finger are more freguently found (50%) than those of control group (37.44%).
Alopecia Areata* ; Alopecia* ; Continental Population Groups ; Dermatoglyphics* ; Dermatology ; Fingers ; Hand ; Haplorhini ; Hominidae ; Humans ; Incidence ; Leprosy ; Male ; Primates ; Psoriasis* ; Skin ; Wills ; Wrist

Stasis eczema is one of the important skin manifestations caused by venous stasia. dueto vascular disturbances. Until now a few casses of stasis eczema accornpanied with inferior vena cava obstruction were reported in the literatures. The patient, 31-year old barber, has been suffered from right upper guadrant abdominal pain and tenderness for 6 years, and had dark brownish mottled scaly eczematoid patches of both lower extremitiea for 6 yrs. Inferiorvenacavogram through the right fernoral vein showed complete obstruction of inferior vena cava above the level of T10, and well developed several collateraI veins. Findings of skin biopsy on the right ankle joint area revealed moderate acanthosis, increased pigrnentation of the basal cell layer in the epidermis, capillary proliferation and hemosiderin granules in the dermis, that is consistent with stasis eczema. Possible etiological factor of inferior vena cava obstruction waa discussed and also reviewed with literatvre.
Abdominal Pain ; Adult ; Ankle Joint ; Biopsy ; Capillaries ; Dermis ; Eczema* ; Epidermis ; Hemosiderin ; Humans ; Skin ; Skin Manifestations ; Veins ; Vena Cava, Inferior

No abstract available.
Humans ; Hyperplasia* ; Prostate* ; Transurethral Resection of Prostate* ; Urinary Bladder Neck Obstruction

Dermatoglyphics has been studied in various diseases including mongolism, ruhella syndrome, congenital heart disease, selected neurologic diseases and other disorders. However, reports of derrnatoglyphic studies in patients with leprosy have not been evcountered a lot. Although Ieprasy is an infectious disease due to the hfycobacterium leprae, the hereditary susceptibility of the host to the organism is proposed as an additional predisposing factor. Thia concept has been proposed to reconcile the low incidence of lisease among large numbers of contacts. Most reports delving into the role of heredity in leprosy have been related ta epidemiological studies. Prasad and Mohamad suggest, on the basis of data related to rnultiple patient families, that the acquisition of leprosy may be determined genetically on the assumption of incomplete dominance of genes; on the other hand, Spickett suggested that if there is any genetic effect, it is but a component af the familial effect. This study of dennatoglyphics in 77 male leprosy patients was undcataken to determine if there might be significance in the analysis of dermal patterns af the hands as related to the hereditary susceptibility of individuals to the disease comparing with those of 234 healthy Korean soldiers. Results are as follows: 1. In the analysis of the total fingertip ridges, there is significant difference (P<0.01) between the leprosy (137.66+4.7) and the control group (152.93+9.50). 2. A aignificant statistical difference between the leprosy and the control group (14.73+2.79) does not exist with respect to the pattern intensity, however that af the borderline group of leprosy (12.00+5.09)is decreased (P<0.025). 3. In the incidence of simian lines, the leprosy group (5.20%) shows lower incidence rate than that of control group (8.98%). 4. As for the a-b ridge count, it is decreased significantly (P<0.05) in the left hand of leprosy group (34.71+0.87) than that of the eontrol group (37.11+0.52), Also there is significant difference(P<0. 05) in the right hands of tuberculoid type of leprosy (34.64+1.38). 5. With respect to the propoetional distance (mm.) between the distal flexion crease of the wrist to the base of the middle finger with the distance (mm.) of the same point of the wrist to the axial triradius, a significant statistical difference between the leprosy and the control group does not exist, but significantly longer distance (mm.) exists in the tuberculoid type of leprosy (P<0.05). 6. No significant fingertip pattern differences are noted between the leprosy and the control group.
Causality ; Communicable Diseases ; Dermatoglyphics* ; Down Syndrome ; Epidemiologic Studies ; Fingers ; Hand ; Heart Defects, Congenital ; Heredity ; Humans ; Incidence ; Korea* ; Leprosy* ; Male ; Military Personnel ; Wrist

BACKGROUND: Familial aggregation of coronary risk factors is well known, which are hypertension, hyperlipidemia, diabetes mellitus, and obesity. However inter-spouse relation of the risk factors has remained controversial. As spouses are not blood-related, any risk factor relation that exist probably may not reflect genetic factors, but the environmental factors to which the couple is exposed. Moreover, the effect of assortative marriage should be considered. This study is designed to identify inter-spouse relation of coronary risk factors and to document the effects of marriage duration to spouse concordance. METHODS: From May 1995 to March. 1999, we enrolled 1,859 couples who had visited the Health Promotion Center at Seoul National University Hospital. We analysed inter-spouse correlation of body mass index, blood pressure, glucose, serum lipid factors, uric acid, smoking, alcohol drinking, and stress known as coronary risk factors. The correlation coefficients were compared according to marriage duration. RESULTS: There was statistically significant spouse concordance for all risk factors with the exception of smoking. The correlation coefficients of blood pressure, total cholesterol, and triglyceride increased with marriage duration but troughed at 30-39 years of marriage. Those of body mass index and glucose peaked at early and late marriage duration. Those of HDL-cholesterol and uric acid was relatively fixed throughout marriage. CONCLUSION: The presence of significant inter-spouse correlation for most of the coronary risk factors reflect the influence of assortative marriage and environmental factors on spouse concordance. If a spouse has many cardiovascular risk factors, partner should be evaluated for risk factors.
Alcohol Drinking ; Blood Pressure ; Body Mass Index ; Cardiovascular Diseases ; Cholesterol ; Diabetes Mellitus ; Family Characteristics ; Glucose ; Health Promotion ; Humans ; Hyperlipidemias ; Hypertension ; Marriage* ; Obesity ; Risk Factors* ; Seoul ; Smoke ; Smoking ; Spouses* ; Triglycerides ; Uric Acid

CT was done 81 times on 63 proven malignant maxillary sinus tumors for 3 years from Feb.1979 to May 1982 atSeoul National University Hospital. Pre-treatment CT were 54 and post-treatment CT were 31 on 28 patient. Theresult were as follows; 1. The most frequent histopathologic diagnosis was 44 cases (69.8%) of squamous cellcarcinoma. Others were 5 cases (7.9%) of adenoid cystic carcinoma, 3 cases (4.8%) of olfactory neuroblastoma, 3cases (4.8%) of malignant lymphoma, 2 cases (3.2%) of melanoma, 2 cases (3.2%) of malignant fibrous histiocytoma,a rhabdomyosarcoma, a basal cell carcioma, a fibrosarcoma and a metastatic carcinoma from thyroid follicular adenocarcinoma. 2. The CT findings in 54 untreated malignant maxillary sinus tumors were sinus opacification, softtissue mass, and bone destruction in all cases. Other findings were fat plane obliteration (70%),osteosclerosis(59%), bone erosion and displacement (46%), low densities within soft tissue mass (27%), and airdensitis wiithin soft soft tissue mass (27%), and air densities within soft tissue mass(13%). 3. The value of pre-treatment CT in malignant maxillary sinus tumors were outlining the disease process especially soft tissuesuch as orbit, infratemporal fossa, pterygopalatine fossa, nasopharynx, pterygoid fossa and intracranialextension, and CT is the choice of diagnostic modality to determine the prognosis and the therapeutic planning insurgery and/or radiotherapy. 4. Post-treatment CT is also helpful to evalute the change in tumor size andpost-treatment complication.
Adenocarcinoma, Follicular ; Carcinoma, Adenoid Cystic ; Diagnosis ; Esthesioneuroblastoma, Olfactory ; Fibrosarcoma ; Humans ; Lymphoma ; Maxillary Sinus ; Melanoma ; Nasopharynx ; Orbit ; Prognosis ; Pterygopalatine Fossa ; Radiotherapy ; Rhabdomyosarcoma ; Thyroid Gland

PURPOSE: To review the short-term result of Raz`s anterior vaginal wall sling as a treatment for intrinsic sphincter deficiency(ISD) and urethral hypermobility. MATERIALS AND METHODS: Twenty-three women who had intrinsic sphincter deficiency and urethral hypermobility were treated by AVL which employed an island of in situ anterior vaginal wall as a sling to support the bladder neck and mid-urethra. RESULTS: After a mean follow-up of 4.7(3-6)months, urinary incontinence was disappeared completely after the AVL. Complications included urinary retention in 6 patients, residual urine sensation in 5 patients which improved after intermittent catheterization. The other complication was low abdominal pain in 5 patients. CONCLUSIONS: It is suggested that AVL was effective treatment of ISD and urethral hypermobility with simple technique, low morbidity and high cure rate.
Abdominal Pain ; Catheterization ; Catheters ; Female* ; Follow-Up Studies ; Humans ; Neck ; Sensation ; Urinary Bladder ; Urinary Incontinence* ; Urinary Retention

BACKGROUND: Korea is an endemic area of viral hepatitis B with a rate of 5~10% carrier state. Therefore, hepatitis B vaccination is performed nationwide. But 5~15% of healthy individuals fail to respond adequately to the vaccine and an approved guideline for the nonresponders has not been developed yet. This study is designed to identify risk factors for those who lack anti-HBs after hepatitis B vaccination and to document the results of a double-dose revaccination in such nonresponders to the primary vaccination. METHODS: From Feb. 1996 to Aug, 1997, we assessed 51 healthy subjects(HBs Ag negative, anti-HBs negative, anti-HBc negative and a normal LFT). All subjects were vaccinated with Hepavax- B, 1.0ml, 24 by a rapid schedule(0, 1, and 2 months) and 27 by a standard schedule(0, 1, and 6 months). Anti-HBs titers were evaluated 3 months after the third vaccine and assessed the nonre-sponders (anti-HBs titer<2mIu/ml) and the hyporesponders(2~10mK/ml). All 13 nonresponders were revaccinated with 2ml of Hepavax-B 3 months after the primary vaccination. Anti-HBs titers were evaluated 1 month later. RESULTS: The differences in age(p<0.01) and smoking amount(p<0.05) between the responders and the hypo and the nonresponders were statistically significant. There were more males and higher body mass index in the hypo and the nonresponders but not statistically significant. The seroconversion rate after the double-dose vaccination was 92.3%(12/13) with an average titer of 5K08mlU/ ml(1-132.4mIU/ml). CONCLUSIONS: Increase in age and smoking amount were the risk factors of the nonresponders after the primary vaccination. Most of the hypo and the nonresponders to the primary vaccination responded adequately to the double-dose revaccination.
Body Mass Index ; Carrier State ; Hepatitis B* ; Hepatitis* ; Humans ; Immunization, Secondary* ; Korea ; Male ; Risk Factors* ; Smoke ; Smoking ; Vaccination

PURPOSE: We intend to report that a case of total Descemet's membrane detachment, occured after cataract operation which was reattached with non-expansible SF6 gas infusion. METHODS: 77-year-old woman who was undertaken cataract surgey 7days ago showed corneal edema, decreased visual acuity and rolled detached Descemet's membrane which was attached inferior cornea. Nine days after cataract surgery, 0.25 ml of non-expansible SF6 gas 20% was infused into anterior chamber. RESULTS: Three days after intracameral injection of non-expansible SF6 gas 20%, Descemet's membrane was begin to reattach and corneal edema was improved progressively. CONCLUSIONS: When total Descemet's membrane detachment occurs after intraocular surgery, intracameral injection of non-expansible SF6 gas is to be a effective treatment.
Aged ; Anterior Chamber ; Cataract ; Cornea ; Corneal Edema ; Descemet Membrane ; Female ; Humans ; Visual Acuity

PURPOSE: The purpose of this study is to determine the ideal period of brace application for thoracolumbar (T10-L2) osteoporotic vertebral compression fracture (OVCF) based on the progression of the vertebral compression with passage of time and to evaluate the factors associated with progression of thoracolumbar OVCF, when treated conservatively. MATERIALS AND METHODS: This retrospective study included a total of 46 patients who were diagnosed with thoracolumbar OVCF and could be followed-up for at least 6 months. In this study, the increase of compression rate and the mean slope of compression rate per weeks were compared between two periods (from diagnosed date to 8 weeks and from 8 weeks to 6 months), as the standard point. Age, bone mineral density (BMD), osteoporosis treatment after injury, diabetes mellitus (DM) as underlying disease were also compared between two groups (setting up 15% as standard point of increase of compression rate, <15% and > or =15%). Statistical analyses were performed using the paired t-test to assess the increase of compression rate and using the linear mixed model to assess the mean slope change. The relationships between the factors and progression of compression were analyzed using t-test, chi-square test, and logistic regression analysis. RESULTS: The increase of compression rate was 13.03% and 1.97% in each period and the difference between those two periods was 11.06% (p=0.00). At 8 weeks of follow-up, the mean slope was reduced by 1.12 (p=0.00). No statistically significant difference in related factors was observed between two groups. CONCLUSION: Considering the increase of compression rate with passage of time, brace should be applied strictly for an initial 8 weeks. And age, BMD, osteoporosis treatment after injury, and DM as underlying disease are not predictors of progression of compression in vertebral fractures.
Bone Density ; Braces ; Diabetes Mellitus ; Follow-Up Studies ; Fractures, Compression* ; Humans ; Logistic Models ; Osteoporosis ; Retrospective Studies